Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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5 mg | 在庫あり | ¥ 10,000 | |||
10 mg | 在庫あり | ¥ 14,000 | |||
25 mg | 在庫あり | ¥ 20,500 | |||
50 mg | 在庫あり | ¥ 27,000 | |||
100 mg | 在庫あり | ¥ 37,500 | |||
500 mg | 在庫あり | ¥ 91,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 16,500 |
説明 | Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention. |
ターゲット&IC50 | FXa:0.561 nM(Ki) |
In vitro | In thrombosis models involving rats and rabbits, Edoxaban demonstrates a dose-dependent inhibition of thrombus formation. Edoxaban (p.o.) elicits effective anti-Xa activity and achieves high plasma drug concentrations in both rats and monkeys. |
In vivo | Edoxaban (0.256 and 0.508 μM) doubles the prothrombin time in human plasma and partially activates the thromboplastin time. |
別名 | DU-176b, DU-176b tosylate Monohydrate, Lixiana, Edoxaban |
分子量 | 738.27 |
分子式 | C31H40ClN7O8S2 |
CAS No. | 1229194-11-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 93 mg/mL (126 mM)
You can also refer to dose conversion for different animals. 詳細
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Edoxaban Tosylate Monohydrate 1229194-11-9 Metabolism Proteases/Proteasome Factor Xa Thrombin DU-176b DU-176b tosylate Monohydrate Fxa inhibit stroke Lixiana Edoxaban DU-176b Tosylate antithrombotic thromboembolic anticoagulant Inhibitor Edoxaban tosylate Edoxaban Tosylate inhibitor