Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SR0987 is a RORγt agonist,
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 15,000 | |||
10 mg | 在庫あり | ¥ 26,000 | |||
25 mg | 在庫あり | ¥ 52,500 | |||
50 mg | 在庫あり | ¥ 91,500 | |||
100 mg | 在庫あり | ¥ 135,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 16,000 |
説明 | SR0987 is a RORγt agonist, |
ターゲット&IC50 | RORγt:800 nM (EC50) |
In vitro | Treatment with SR0987 leads to a significant decrease in the surface expression of PD-1, while desmosterol shows no impact on this parameter. Co-treatment with SR0987 and desmosterol suggests a potential increase in IL17 production. Additionally, SR0987 exhibits a concentration-dependent stimulation of reporter gene expression, achieving an effective concentration (EC50) of approximately 800nM. |
分子量 | 397.7 |
分子式 | C16H10ClF6NO2 |
CAS No. | 303126-97-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (113.15 mM)
You can also refer to dose conversion for different animals. 詳細
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SR0987 303126-97-8 Metabolism ROR SR 0987 Inhibitor SR-0987 inhibit RAR-related orphan receptor inhibitor