Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Taletrectinib (AB-106) is a new-generation selective inhibitor of ROS1/NTRK including ROS1,NTRK1,NTRK2 and NTRK3 with IC50 of 0.207 nM,0.622 nM,2.28 nM and 0.980 nM, respectively.
説明 | Taletrectinib (AB-106) is a new-generation selective inhibitor of ROS1/NTRK including ROS1,NTRK1,NTRK2 and NTRK3 with IC50 of 0.207 nM,0.622 nM,2.28 nM and 0.980 nM, respectively. |
ターゲット&IC50 | TrkA:0.622 nM, TrkB:2.28 nM, ROS1:0.207 nM, TrkC:0.980 nM |
別名 | DS-6051b, AB-106 |
分子量 | 551.61 |
分子式 | C29H34FN5O5 |
CAS No. | 1505515-69-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (81.58 mM)
You can also refer to dose conversion for different animals. 詳細
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Taletrectinib 1505515-69-4 Immunology/Inflammation Tyrosine Kinase/Adaptors ROS Trk receptor ROS Kinase mutations DS-6051b AB 106 inhibit antitumor AB106 glioblastoma Inhibitor colorectal AB-106 cancer NSCLC rearrangement inhibitor