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Search Results for " rearrangement "

ターゲット

10

阻害剤

1

天然化合物

22

リコンビナントタンパク質

2

ライブラリー

カタログ番号 製品名 別名 ターゲット
T9760 IC 86621 DNA-PK
IC 86621 is a selective and reversible ATP-competitive inhibitor of DNA-PK with an IC50 of 120 nM. IC 86621 increases DNA double-strand break(DSB)-induced antitumor activity with an EC50 of 68 µM for DNA-PK mediated cell...
T2029 Bohemine ERK , CDK
Bohemine is a cyclin-dependent kinase inhibitor.
T22318 Taletrectinib DS-6051b,AB-106 Trk receptor , ROS , ROS Kinase
Taletrectinib (AB-106) is a new-generation selective inhibitor of ROS1/NTRK including ROS1,NTRK1,NTRK2 and NTRK3 with IC50 of 0.207 nM,0.622 nM,2.28 nM and 0.980 nM, respectively.
T3678 Entrectinib RXDX-101,NMS-E628 Trk receptor , ROS , ALK , Autophagy , ROS Kinase
Entrectinib (RXDX-101) is an inhibitor of TrkA (IC50: 1.7 nM), TrkB (IC50: 0.1 nM), and TrkC (IC50: 0.1 nM), as well as anaplastic lymphoma kinase (ALK; IC50: 1.6 nM) and C-ros oncogene 1 (ROS1; IC50: 0.2 nM). Entrectini...
T63358 RET-IN-15
RET-IN-15 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research.
T63230 RET-IN-8
RET-IN-8 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research.
T37925 7-Biopterin
7-Biopterin is a 7-substituted pterin.1It is formed by non-enzymatic rearrangement of 4a-hydroxy-tetrahydropterin in the absence of pterin-4a-carbinolamine dehydratase (PCD)in vitroand levels are elevated in the urine of...
T68413 CBS1194
CBS1194 is a novel antiviral agent against influenza A virus (IAV), and is more specifically, a group 2 IAV fusion inhibitor. CBS1194 prevents membrane fusion of the virus through the inhibition of the conformational cha...
T35491 3,5-dimethyl PIT-1
PtdIns-(3,4,5)-P3 (PIP3) serves as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains such as phosphatidylinositol 3-kinase (PI3K) or PTEN. Protein binding to PIP3 is impor...
T36939 PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) (ammonium salt) PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) (ammonium salt)
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3, als...
カタログ番号 製品名 別名 ターゲット
T1085 L-Glutathione reduced GSH,Isethion,Glutathione,γ-L-Glutamyl-L-cysteinyl-glycine,Glutathion,Tathion Ferroptosis , Reactive Oxygen Species , Endogenous Metabolite , Glutathione reductase
L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals. L-Glutathione reduced is a cofactor for certain enzymes and is invo...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-04548 CDK4 Protein, Human, Recombinant (GST) Human Baculovirus Insect Cells
CDK4 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cel...
TMPH-00557 DXP reductoisomerase Protein, E. coli, Recombinant (His & Myc) E. coli E. coli
Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
TMPJ-00461 PDIA5 Protein, Human, Recombinant (His) Human HEK293 Cells
Protein disulfide-isomerase A5 is a 519 amino acids protein that belongs to the protein disulfide isomerase family.It contains 3 thioredoxin domains.It can catalyze the rearrangement of -S-S- bonds in proteins.
TMPH-01244 POLM Protein, Human, Recombinant (His) Human E. coli
Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination. POLM Protein, Human, ...
TMPH-01245 POLM Protein, Human, Recombinant (His & Myc) Human Baculovirus Insect Cells
Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination. POLM Protein, Human, ...
TMPH-01226 CRMP1 Protein, Human, Recombinant Human E. coli
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance. During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F...
TMPK-01324 S100A9 Protein, Canine, Recombinant (His) Canine E. coli
S100A8 and S100A9 (also known as MRP8 and MRP14, respectively) are Ca2 binding proteins belonging to the S100 family. They often exist in the form of heterodimer, while homodimer exists very little because of the stabili...
TMPK-01259 S100A9 Protein, Cynomolgus, Recombinant (His) Cynomolgus E. coli
S100A8 and S100A9 (also known as MRP8 and MRP14, respectively) are Ca2 binding proteins belonging to the S100 family. They often exist in the form of heterodimer, while homodimer exists very little because of the stabili...
TMPJ-01069 Serpin A1e Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Alpha-1-antitrypsin 1-5(SERPIN A1) is a secreted protein and belongs to the serpin family. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-...
TMPY-02769 RNASET2 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
RNASET2 (ribonuclease T2) is an enzyme that belongs to the RNase T2 family. It is highly expressed in the temporal lobe and fetal brain. RNASET2 gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular r...
TMPY-01303 Serpin A3 Protein, Human, Recombinant (His) Human HEK293 Cells
SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a plasma alpha globulin glycoprotein, and is a member of serpin superfamily of the serine protease inhibitors consisting of at least 35 members. SerpinA3 has be...
TMPY-02888 MAX Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
MYC associated factor X contains 1 basic helix-loop-helix (bHLH) domain and belongs to the MAX family. It is highly expressed in the brain, heart, and lung while lower levels are seen in the liver, kidney, and skeletal m...
TMPH-02168 TRAC Protein, Human, Recombinant (E. coli, His) Human E. coli
Constant region of T cell receptor (TR) alpha chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize p...
TMPJ-00748 Ig kappa Protein, Human, Recombinant (His) Human HEK293 Cells
Immunoglobulin Kappa is constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humor...
TMPY-02135 S100A16 Protein, Human, Recombinant Human E. coli
S100A16 is a member of S100 protein superfamily that carries calcium-binding EF-hand motifs. S100 proteins are cell- and tissue-specific and are involved in many intra- and extracellular processes through interacting wit...
TMPY-03504 CBFB Protein, Human, Recombinant (His) Human E. coli
CBFB is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and os...
TMPY-02131 Acid Phosphatase/ACP1 Protein, Human, Recombinant (GST) Human E. coli
The low molecular weight phosphotyrosine phosphatase (LMW-PTP), also known as Acid phosphatase 1 (ACP1), belongs to the low molecular weight phosphotyrosine protein phosphatase family are involved in the regulation of im...
TMPH-02173 TRBC2 Protein, Human, Recombinant (His & Myc) Human E. coli
Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPY-04566 CAMKV Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
CaM kinase-like vesicle-associated protein, also known as CAMKV, is a peripheral membrane protein and Cytoplasmic vesicle membrane protein which belongs to theprotein kinase superfamily and CAMK Ser/Thr protein kinase...
TMPY-03046 APCDD1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Osteosarcoma (OS) is the most common type of bone tumor in children and adults. The expression of APCDD1, a Wnt antagonist, was reduced in OS tissues and cells compared to adjacent normal tissue and osteoblast cells, res...
TMPH-02169 TRBC1 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPH-03741 BoNT/F Protein, Clostridium botulinum, Recombinant (His) Clostridium botulinum E. coli
Botulinum toxin causes flaccid paralysis by inhibiting neurotransmitter (acetylcholine) release from the presynaptic membranes of nerve terminals of the eukaryotic host skeletal and autonomic nervous system, with frequen...
CDK4 Protein, Human, Recombinant (GST)
TMPY-04548
Species: Human
Expression System: Baculovirus Insect Cells
DXP reductoisomerase Protein, E. coli, Recombinant (His & Myc)
TMPH-00557
Species: E. coli
Expression System: E. coli
PDIA5 Protein, Human, Recombinant (His)
TMPJ-00461
Species: Human
Expression System: HEK293 Cells
POLM Protein, Human, Recombinant (His)
TMPH-01244
Species: Human
Expression System: E. coli
POLM Protein, Human, Recombinant (His & Myc)
TMPH-01245
Species: Human
Expression System: Baculovirus Insect Cells
CRMP1 Protein, Human, Recombinant
TMPH-01226
Species: Human
Expression System: E. coli
S100A9 Protein, Canine, Recombinant (His)
TMPK-01324
Species: Canine
Expression System: E. coli
S100A9 Protein, Cynomolgus, Recombinant (His)
TMPK-01259
Species: Cynomolgus
Expression System: E. coli
Serpin A1e Protein, Mouse, Recombinant (His)
TMPJ-01069
Species: Mouse
Expression System: HEK293 Cells
RNASET2 Protein, Human, Recombinant (His)
TMPY-02769
Species: Human
Expression System: Baculovirus Insect Cells
Serpin A3 Protein, Human, Recombinant (His)
TMPY-01303
Species: Human
Expression System: HEK293 Cells
MAX Protein, Human, Recombinant (His & GST)
TMPY-02888
Species: Human
Expression System: Baculovirus Insect Cells
TRAC Protein, Human, Recombinant (E. coli, His)
TMPH-02168
Species: Human
Expression System: E. coli
Ig kappa Protein, Human, Recombinant (His)
TMPJ-00748
Species: Human
Expression System: HEK293 Cells
S100A16 Protein, Human, Recombinant
TMPY-02135
Species: Human
Expression System: E. coli
CBFB Protein, Human, Recombinant (His)
TMPY-03504
Species: Human
Expression System: E. coli
Acid Phosphatase/ACP1 Protein, Human, Recombinant (GST)
TMPY-02131
Species: Human
Expression System: E. coli
TRBC2 Protein, Human, Recombinant (His & Myc)
TMPH-02173
Species: Human
Expression System: E. coli
CAMKV Protein, Human, Recombinant (His & GST)
TMPY-04566
Species: Human
Expression System: Baculovirus Insect Cells
APCDD1 Protein, Human, Recombinant (hFc)
TMPY-03046
Species: Human
Expression System: HEK293 Cells
TRBC1 Protein, Human, Recombinant (His)
TMPH-02169
Species: Human
Expression System: P. pastoris (Yeast)
BoNT/F Protein, Clostridium botulinum, Recombinant (His)
TMPH-03741
Species: Clostridium botulinum
Expression System: E. coli
カタログ番号 製品名
L8300 Chromatin Modification Compound Library

250 compounds
A unique collection of 250 compounds targeting chromatin remodeling pathway for high throughput screening (HTS) and high content screening (HCS);
L6000 Natural Product Library for HTS

4533 compounds
A unique collection of 4533 pure natural products and their derivatives with known biological activity for drug discovery, pharmacological study, stem cell differentiation, fingerprint study and quality research, and can...