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カタログ番号 | 製品名 | 別名 | ターゲット |
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T9760 | IC 86621 | DNA-PK | |
IC 86621 is a selective and reversible ATP-competitive inhibitor of DNA-PK with an IC50 of 120 nM. IC 86621 increases DNA double-strand break(DSB)-induced antitumor activity with an EC50 of 68 µM for DNA-PK mediated cell... | |||
T2029 | Bohemine | ERK , CDK | |
Bohemine is a cyclin-dependent kinase inhibitor. | |||
T22318 | Taletrectinib | DS-6051b,AB-106 | Trk receptor , ROS , ROS Kinase |
Taletrectinib (AB-106) is a new-generation selective inhibitor of ROS1/NTRK including ROS1,NTRK1,NTRK2 and NTRK3 with IC50 of 0.207 nM,0.622 nM,2.28 nM and 0.980 nM, respectively. | |||
T3678 | Entrectinib | RXDX-101,NMS-E628 | Trk receptor , ROS , ALK , Autophagy , ROS Kinase |
Entrectinib (RXDX-101) is an inhibitor of TrkA (IC50: 1.7 nM), TrkB (IC50: 0.1 nM), and TrkC (IC50: 0.1 nM), as well as anaplastic lymphoma kinase (ALK; IC50: 1.6 nM) and C-ros oncogene 1 (ROS1; IC50: 0.2 nM). Entrectini... | |||
T63358 | RET-IN-15 | ||
RET-IN-15 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research. | |||
T63230 | RET-IN-8 | ||
RET-IN-8 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research. | |||
T37925 | 7-Biopterin | ||
7-Biopterin is a 7-substituted pterin.1It is formed by non-enzymatic rearrangement of 4a-hydroxy-tetrahydropterin in the absence of pterin-4a-carbinolamine dehydratase (PCD)in vitroand levels are elevated in the urine of... | |||
T68413 | CBS1194 | ||
CBS1194 is a novel antiviral agent against influenza A virus (IAV), and is more specifically, a group 2 IAV fusion inhibitor. CBS1194 prevents membrane fusion of the virus through the inhibition of the conformational cha... | |||
T35491 | 3,5-dimethyl PIT-1 | ||
PtdIns-(3,4,5)-P3 (PIP3) serves as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains such as phosphatidylinositol 3-kinase (PI3K) or PTEN. Protein binding to PIP3 is impor... | |||
T36939 | PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) (ammonium salt) | PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) (ammonium salt) | |
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3, als... |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T1085 | L-Glutathione reduced | GSH,Isethion,Glutathione,γ-L-Glutamyl-L-cysteinyl-glycine,Glutathion,Tathion | Ferroptosis , Reactive Oxygen Species , Endogenous Metabolite , Glutathione reductase |
L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals. L-Glutathione reduced is a cofactor for certain enzymes and is invo... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-04548 | CDK4 Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
CDK4 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cel... | |||
TMPH-00557 | DXP reductoisomerase Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). | |||
TMPJ-00461 | PDIA5 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Protein disulfide-isomerase A5 is a 519 amino acids protein that belongs to the protein disulfide isomerase family.It contains 3 thioredoxin domains.It can catalyze the rearrangement of -S-S- bonds in proteins. | |||
TMPH-01244 | POLM Protein, Human, Recombinant (His) | Human | E. coli |
Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination. POLM Protein, Human, ... | |||
TMPH-01245 | POLM Protein, Human, Recombinant (His & Myc) | Human | Baculovirus Insect Cells |
Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination. POLM Protein, Human, ... | |||
TMPH-01226 | CRMP1 Protein, Human, Recombinant | Human | E. coli |
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance. During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F... | |||
TMPK-01324 | S100A9 Protein, Canine, Recombinant (His) | Canine | E. coli |
S100A8 and S100A9 (also known as MRP8 and MRP14, respectively) are Ca2 binding proteins belonging to the S100 family. They often exist in the form of heterodimer, while homodimer exists very little because of the stabili... | |||
TMPK-01259 | S100A9 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | E. coli |
S100A8 and S100A9 (also known as MRP8 and MRP14, respectively) are Ca2 binding proteins belonging to the S100 family. They often exist in the form of heterodimer, while homodimer exists very little because of the stabili... | |||
TMPJ-01069 | Serpin A1e Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Alpha-1-antitrypsin 1-5(SERPIN A1) is a secreted protein and belongs to the serpin family. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-... | |||
TMPY-02769 | RNASET2 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
RNASET2 (ribonuclease T2) is an enzyme that belongs to the RNase T2 family. It is highly expressed in the temporal lobe and fetal brain. RNASET2 gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular r... | |||
TMPY-01303 | Serpin A3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a plasma alpha globulin glycoprotein, and is a member of serpin superfamily of the serine protease inhibitors consisting of at least 35 members. SerpinA3 has be... | |||
TMPY-02888 | MAX Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
MYC associated factor X contains 1 basic helix-loop-helix (bHLH) domain and belongs to the MAX family. It is highly expressed in the brain, heart, and lung while lower levels are seen in the liver, kidney, and skeletal m... | |||
TMPH-02168 | TRAC Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Constant region of T cell receptor (TR) alpha chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize p... | |||
TMPJ-00748 | Ig kappa Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Immunoglobulin Kappa is constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humor... | |||
TMPY-02135 | S100A16 Protein, Human, Recombinant | Human | E. coli |
S100A16 is a member of S100 protein superfamily that carries calcium-binding EF-hand motifs. S100 proteins are cell- and tissue-specific and are involved in many intra- and extracellular processes through interacting wit... | |||
TMPY-03504 | CBFB Protein, Human, Recombinant (His) | Human | E. coli |
CBFB is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and os... | |||
TMPY-02131 | Acid Phosphatase/ACP1 Protein, Human, Recombinant (GST) | Human | E. coli |
The low molecular weight phosphotyrosine phosphatase (LMW-PTP), also known as Acid phosphatase 1 (ACP1), belongs to the low molecular weight phosphotyrosine protein phosphatase family are involved in the regulation of im... | |||
TMPH-02173 | TRBC2 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe... | |||
TMPY-04566 | CAMKV Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
CaM kinase-like vesicle-associated protein, also known as CAMKV, is a peripheral membrane protein and Cytoplasmic vesicle membrane protein which belongs to theprotein kinase superfamily and CAMK Ser/Thr protein kinase... | |||
TMPY-03046 | APCDD1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Osteosarcoma (OS) is the most common type of bone tumor in children and adults. The expression of APCDD1, a Wnt antagonist, was reduced in OS tissues and cells compared to adjacent normal tissue and osteoblast cells, res... | |||
TMPH-02169 | TRBC1 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe... | |||
TMPH-03741 | BoNT/F Protein, Clostridium botulinum, Recombinant (His) | Clostridium botulinum | E. coli |
Botulinum toxin causes flaccid paralysis by inhibiting neurotransmitter (acetylcholine) release from the presynaptic membranes of nerve terminals of the eukaryotic host skeletal and autonomic nervous system, with frequen... |
カタログ番号 | 製品名 | ||
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L8300 | Chromatin Modification Compound Library | 250 compounds | |
A unique collection of 250 compounds targeting chromatin remodeling pathway for high throughput screening (HTS) and high content screening (HCS); | |||
L6000 | Natural Product Library for HTS | 4533 compounds | |
A unique collection of 4533 pure natural products and their derivatives with known biological activity for drug discovery, pharmacological study, stem cell differentiation, fingerprint study and quality research, and can... |