Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Terevalefim (ANG-3777) is an hepatocyte growth factor (HGF) mimetic. Terevalefim selectively activates the c-Met receptor.
説明 | Terevalefim (ANG-3777) is an hepatocyte growth factor (HGF) mimetic. Terevalefim selectively activates the c-Met receptor. |
In vitro | Terevalefim (ANG-3777) (0-10 μM) significantly inhibited cancer cells proliferation in HUVECs[2]. |
In vivo | Terevalefim (ANG-3777) decreases apoptosis, increases proliferation, and promotes organ repair and function in animal models[1].Terevalefim (ANG-3777, 40 mg/kg, IP) phosphorylates the c-Met receptor in rats[2]. |
分子量 | 176.24 |
分子式 | C9H8N2S |
CAS No. | 1070881-42-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (567.41 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Terevalefim 1070881-42-3 Tyrosine Kinase/Adaptors c-Met/HGFR ANG-3777 injury acute inhibit ANG 3777 AKI kidney ANG3777 transplantation HGF Inhibitor inhibitor