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カタログ番号 | 製品名 | 別名 | ターゲット |
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T64338 | AKI603 | AKI 603,AKI-603 | Aurora Kinase |
AKI603 is a novel small molecule inhibitor of Aurora kinase A (AurA)(IC50 = 12.3 nM). AKI603 is developed to overcome resistance mediated by BCR-ABL-T315I mutation. AKI603 exhibits strong anti-proliferative activity in l... | |||
T68332 | AKI-001 | ||
AKI-001 is a potent Aurora kinase inhibitor, which exhibits low nanomolar potency against both Aurora A and Aurora B enzymes, excellent cellular potency (IC50 < 100 nM), and good oral bioavailability. Phenotypic cellular... | |||
T37596 | Terevalefim | c-Met/HGFR | |
Terevalefim (ANG-3777) is an hepatocyte growth factor (HGF) mimetic. Terevalefim selectively activates the c-Met receptor. | |||
T1439 | Lacidipine | SN-305,GX-1048,GR-43659X | Apoptosis , Calcium Channel , Reactive Oxygen Species |
Lacidipine (SN-305) is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex tachycardia. It displays specifi... | |||
T28950 | Terlakiren | CP 80794,CP-80,794 | RAAS |
Terlakiren (CP-80,794) is an orally active and potent renin inhibitor that inhibits the potency of human renin for the study of neurological disorders of the hypertension class. | |||
T76784 | Tildrakizumab | MK 3222,SCH 900222 | IL Receptor |
Tildrakizumab (SCH 900222) is a potent humanized monoclonal antibody against IL-23 (p19 subunit). Tildrakizumab targets single-stranded IL-23 with a Kd value of 136 pM. Tildrakizumab can be used to study psoriasis and ps... | |||
T73695 | Canakinumab | ACZ 885,Ilaris | IL Receptor |
Canakinumab (ACZ885) is a recombinant human IL-1β-targeting monoclonal antibody.Canakinumab has been shown to inhibit human and chorioallantoic monkey IL-1β, with IC50 values of 43.6 and 40.8 pM, respectively.Canakinumab... | |||
T8813 | Tetrakis (4-carboxyphenyl) porphyrin | TCPP,Tetracarboxyphenylporphine | Others |
Tetrakis (4-carboxyphenyl) porphyrin (TCPP) plays the role of a metal remover.Tetrakis (4-carboxyphenyl) porphyrin is a fabricated three dimensional Ru polymer complex. It can be grafted on SiO2/Nb2O5 substrate and subse... | |||
T4264 | Takinib | EDHS-206 | Apoptosis , MAPK |
Takinib (EDHS-206) is a specific and effective TAK1 inhibitor(IC50= 9.5 nM). | |||
TP2075L | Bombinakinin M acetate | Bombinakinin M acetate(509151-65-9 free base) | Bradykinin Receptor |
Bombinakinin M acetate is a potent bradykinin receptor agonist with high selectivity for mammalian arterial smooth muscle bradykinin receptors and is approximately 50 times more potent than bradykinin. | |||
T76775 | Fezakinumab | ILV 094 | Interleukin |
Fezakinumab is a potent monoclonal antibody to interleukin-22 (IL-22). Fezakinumab can be used to study immune system diseases and inflammation-related conditions such as psoriasis, rheumatoid arthritis and atopic dermat... | |||
T66574 | Sodium tetrakis (pentafluorophenyl)-borate | ||
sodium tetrakis (pentafluorophenyl)-borate is a useful organic compound for research related to life sciences and the catalog number is T66574. | |||
TP2225 | Bombinakinin-GAP | Others | |
Bioactive bradykinin-related peptide | |||
T75711 | Contulakin G | ||
Contulakin G, an O-glycosylated invertebrate neurotensin, serves as a weaker agonist for the neurotensin receptor. Additionally, it is recognized as a potent antinociceptive agent [1] [2]. | |||
T67239 | Tetrakis[(S)-(+)-(1-adamantyl)-(N-phthalimido)acetato]dirhodium(II) | ||
Tetrakis[(S)-(+)-(1-adamantyl)-(N-phthalimido)acetato]dirhodium(II) is a useful organic compound for research related to life sciences. The catalog number is T67239 and the CAS number is 909389-99-7. | |||
T32358 | Karakin | Carakin,NSC279515,Karakine,NSC-279515,NSC 279515 | |
Karakin is a group of plant growth regulators. | |||
T32840 | Locustakinin | Ala-phe-ser-ser-trp-gly-NH2,Lomk peptide,Locustakinn | |
Locustakinin is a myotropic peptide. | |||
T77034 | Inbakicept | N-803 | |
Inbakicept (ALT-803) is an IL-15 superagonist complex, consisting of IL-15 mutant and IL-15Rα-Fc fusion. Inbakicept magnifies anti-CD20 mAb-mediated NK-cell responses and antibody-dependent cellular cytotoxicity (ADCC). ... | |||
T82882 | Binetrakin | ||
Binetrakin (Interleukin 4 (human)) is a pleiotropic cytokine derived from T lymphocytes that influences multiple cell types, such as B cells and T cells, and promotes the differentiation of naive helper T cells (Th0 cell... | |||
T80607 | Eblasakimab | CSL-334,ASLAN004 | |
Eblasakimab (also known as ASLAN004 or CSL-334) is a human IgG4 monoclonal antibody that selectively binds to IL13RA1, and is predominantly produced in CHO-K1 cells [1]. | |||
T64631 | 2,4,5,6-Tetrakis(diphenylamino)isophthalonitrile | ||
2,4,5,6-Tetrakis(diphenylamino)isophthalonitrile is a useful organic compound for research related to life sciences and the catalog number is T64631. | |||
T65464 | 4,4′,4″,4″′-(Porphine-5,10,15,20-tetrayl)tetrakis(benzenesulfonic acid) | ||
4,4′,4″,4″′-(Porphine-5,10,15,20-tetrayl)tetrakis(benzenesulfonic acid) is a useful organic compound for research related to life sciences and the catalog number is T65464. | |||
T33396 | Misakimycin | ||
Misakimycin is a mammalian cell growth stimulating substance produced by Streptomyces misakiensis BP-3621. | |||
T76823 | Perakizumab | ||
Perakizumab (RG4934), a humanized IgG1κ monoclonal antibody targeting IL-17A (Interleukin Related), is utilized in the study of autoimmune conditions, including psoriatic arthritis [1]. | |||
T76840 | Vunakizumab | ||
Vunakizumab (Anti-Human IL17A Recombinant Antibody), a recombinant human IgGκ monoclonal antibody, specifically targets and inhibits IL-17A's interaction with its receptor, making it useful for researching autoimmune con... | |||
T73743 | 1,1′,1′′,1′′′-[1,4-Piperazinediylbis(2,1-ethanediylnitrilo)]tetrakis[2-dodecanol] | ||
1,1′,1′′,1′′′-[1,4-Piperazinediylbis(2,1-ethanediylnitrilo)]tetrakis[2-dodecanol], a lipid/lipidoid, is utilized in the synthesis of lipid-based or lipidoid nanoparticles [1]. | |||
T76972 | Tozorakimab | ||
Tozorakimab (MEDI-3506), a human immunoglobulin G1 monoclonal antibody, targets interleukin-33 and is utilized in researching chronic obstructive pulmonary disease (COPD) [1]. | |||
T76935 | Briakinumab | ||
Briakinumab (ABT-874), a fully human anti-IL-12/23p40 monoclonal antibody, selectively targets and neutralizes IL-12 and IL-23. This compound is utilized in the research of various autoimmune disorders, including rheumat... | |||
T76942 | Cendakimab | ||
Cendakimab (RPC4046; ABT 308; CC-93538) is a selective humanized recombinant monoclonal antibody targeting the IL-13 molecule with high specificity. It demonstrates potent affinity for both the wild-type and variant form... | |||
T76914 | Avizakimab | ||
Avizakimab (BOS161721), a humanized IgG1 monoclonal antibody, specifically targets interleukin-21 [1]. | |||
T77171 | Efineptakin alfa | ||
Efineptakin alfa (NT-17), a long-acting recombinant human interleukin-7 (IL-7), promotes the proliferation and survival of CD4+ and CD8+ cells in both humans and mice. It has applications in glioblastoma research [1]. | |||
T126551 | Kakisaponin A | ||
Kakisaponin A is a useful organic compound for research related to life sciences. The catalog number is T126551 and the CAS number is 1003864-78-5. | |||
TNU1667 | 3,5-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl] cytidine | ||
3,5-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl] cytidine is a useful organic compound for research related to life sciences and the catalog number is TNU1667. | |||
T66647 | Octakis-(6-bromo-6-deoxy)-γ-cyclodextrin | ||
Octakis-(6-bromo-6-deoxy)-γ-cyclodextrin is a useful organic compound for research related to life sciences and the catalog number is T66647. | |||
T70781 | Ranakinin | ||
Ranakinin is a novel tachykinin receptor agonist; from the brain of frog, Rana ridibunda. | |||
T76675 | Clazakizumab | ||
Clazakizumab, a monoclonal antibody, demonstrates high affinity and specificity towards the interleukin-6 (IL-6) cytokine, potentially inhibiting the cytokine response in COVID-19 caused by SARS-CoV-2. It is also under r... | |||
T77098 | Netakimab | ||
Netakimab, an anti-IL-17 monoclonal antibody, is utilized in the research of ankylosing spondylitis, psoriatic arthritis, and moderate-to-severe plaque psoriasis [1] [2]. | |||
TP2075 | Bombinakinin M | ||
Potent bradykinin receptor agonist. Highly selective for mammalian arterial smooth muscle bradykinin receptors, displaying ~ 50-fold greater potency than bradykinin. Elicits dose-dependent contractile effects in smooth m... | |||
T80730 | Zigakibart | BION-1301 | |
Zigakibart (BION-1301) is a humanized monoclonal antibody of the IgG4-kappa subtype, targeting TNFSF13 (tumor necrosis factor (TNF) superfamily member 13, APRIL, CD256), and exhibits anti-inflammatory activity [1]. | |||
T80559 | Duvakitug | ||
Duvakitug, a humanized IgG1-λ2 monoclonal antibody, targets TNFSF15/TL1A and is primarily expressed in CHOK1SV cells with endogenous glutamine synthetase (GS) activity. It has applications in the research of Crohn's Dise... | |||
TNU0901 | 4-Amino-1-[3,5-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-beta-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one | ||
4-Amino-1-[3,5-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-beta-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one is a Nucleoside Derivative - Protected nucleoside with NH2/OH group. | |||
T81509 | Perisulfakinin | ||
Perisulfakinin, a satiety-signaling neuropeptide, suppresses the activity of neurons that stimulate general activity [1]. | |||
T76251L | Ac-FEID-CMK TFA | Pyroptosis | |
Ac-FEID-CMK TFA is a selective zebrafish GSDMEb-derived peptide inhibitor that reduces mortality and renal injury in infectious shock.Ac-FEID-CMK TFA inhibits pyroptosis in vivo, attenuates septic AKI (acute kidney injur... | |||
T76251 | Ac-FEID-CMK | ||
Ac-FEID-CMK, a potent peptide inhibitor derived from zebrafish-specific GSDMEb, effectively reduces mortality and kidney injury during septic shock by inhibiting pyroptosis and mitigating acute kidney injury (AKI) in viv... | |||
T33678 | NIR-O2˙– | NIR O2˙–,NIRO2˙– | |
NIR-O2˙– is a NIR NIR O2˙– probe which displays superior sensitivity to NIR O2˙– and has the capability to monitor trace amounts of intracellular NIR O2˙– in AKI in vivo. | |||
T78802 | SIRT5 inhibitor 6 | Sirtuin | |
SIRT5 Inhibitor 6 is a potent, selective, and substrate-competitive inhibitor of SIRT5, exhibiting an IC50 of 3.0 μM, and demonstrates therapeutic potential for treating septic acute kidney injury (AKI) in vivo [1]. | |||
T81177 | Ser@TPP@CUR | ||
Ser nM TPP nM CUR, a derivative of Curcumin, notably mitigates damage in renal tubular epithelial cells and enhances renal function in mice with acute kidney injury (AKI). This compound holds potential for AKI research a... | |||
T38616 | Teprasiran | QPI-1002 | |
Teprasiran (QPI-1002) is an RNA-based compound that transiently suppresses p53-dependent apoptosis, a process involved in the development of acute kidney injury (AKI). | |||
T75268 | 84-B10 | ||
84-B10, a derivative of 3-phenylglutaric acid, inhibits cisplatin-induced tubular ferroptosis, attenuates mitochondrial damage and oxidative stress, and ameliorates acute kidney injury (AKI) resulting from cisplatin admi... | |||
T62298 | PHD2/HDACs-IN-1 | ||
PHD2/HDACs-IN-1 is a potent mixed inhibitor of PHD2/HDACs, acting on PHD2 (IC50: 1.15 μM), HDAC1 (IC50: 19.75 μM), HDAC2 (IC50: 26.60 μM), HDAC16 (IC50: 15.98 μM). HDACs-IN-1 is a low toxicity nephroprotective agent that... |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T2870 | Matrine | Vegard,Matridin-15-one,Matrinium,α-Matrine,(+)-Matrine | Mitophagy , Ferroptosis , Opioid Receptor , Autophagy |
Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist. | |||
TQ0264 | Nigakinone | Others | |
Nigakinone, isolated from Kumu, is an alkaloid with the pharmacological activity. | |||
TN2051 | Perakine | Others | |
Perakine is a natural product of Rauvolfia, Apocynaceae. The catalog number is TN2051 and the CAS number is 4382-56-3. Perakine can be used as a reference standard. | |||
T79944 | 2-O-Sinapoyl makisterone A | COX | |
Compound 2, formally known as 2-O-Sinapoyl makisterone A, is a sinapinic acid-ecdysterone hybrid that acts as a selective inhibitor of COX-2, effectively suppressing the expression of COX-2 protein [1]. | |||
TN5298 | Makisterone A 20,22-monoacetonide | ||
Makisterone A 20,22-monoacetonide is a natural product for research related to life sciences. The catalog number is TN5298 and the CAS number is 245323-24-4. | |||
T37471 | Makisterone A | ||
Makisterone A is an ecdysteroid that drives molting in insects. It binds the heterodimeric ecdysone receptor with nanomolar affinity. | |||
T11712 | Jasplakinolide | Jaspamide,NSC-613009 | Microtubule Associated , Antifungal |
Jasplakinolide(Jaspamide), a naturally occurring cyclic peptide from marine sponges, is a potent inducer of actin polymerization.Jasplakinolide exhibits antifungal and antitumor activity and stabilizes pre-existing actin... | |||
T81153 | Sitakisogenin | ||
Sure, please provide the description of the chemical compound you'd like to be rewritten. | |||
T8181 | Poricoic acid A | Poricoic acid A(F) | Others |
Poricoic acid A (Poricoic acid A(F)) is a natural product with antitumor activity. It also enhances melatonin inhibition of AKI-to-CKD transition by regulating the Gas6/AxlNFκB/Nrf2 axis. |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-05898 | Influenza A H3N2 (A/swine/Miyazaki/2/2013) Hemagglutinin/HA Protein (His) | H3N2 | HEK293 Cells |
Influenza A H3N2 (A/swine/Miyazaki/2/2013) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is A0A077KEB1. | |||
TMPH-03076 | Astakine Protein, Pacifastacus leniusculus, Recombinant (His & Myc) | Pacifastacus leniusculus | E. coli |
Cytokine directly involved in hematopoiesis. Astakine Protein, Pacifastacus leniusculus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 16... | |||
TMPH-03701 | Vespakinin-M Protein, Vespa mandarinia, Recombinant (His & KSI) | Vespa mandarinia | E. coli |
Bradykinins are a potent but short-lived agent of arteriolar dilation and increased capillary permeability. May target bradykinin receptors (BDKRB). May cause hypotension. Vespakinin-M Protein, Vespa mandarinia, Recombin... | |||
TMPH-00059 | Major allergen Ani s 1 Protein, Anisakis simplex, Recombinant (His & Myc) | Anisakis simplex | E. coli |
Major allergen Ani s 1 Protein, Anisakis simplex, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 26.3 kDa and the accession number is Q7Z1... | |||
TMPY-05878 | Influenza A H1N2 (A/swine/Miyazaki/1/2006) Hemagglutinin/HA Protein (His) | H1N2 | HEK293 Cells |
Influenza A H1N2 (A/swine/Miyazaki/1/2006) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.4 kDa and the accession number is B3IYD3. |