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T72104 |
AKT Kinase Inhibitor hydrochloride
|
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AKT Kinase Inhibitor hydrochloride is an Akt kinase inhibitor with anti-tumor activity . |
|
T7885 |
Afuresertib hydrochloride
|
|
ROCK
,
Akt
,
PKC
|
|
Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively) |
|
T12412L |
PDK4-IN-1 hydrochloride
|
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Apoptosis
,
PDK
|
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|
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TQ0138 |
K145 hydrochloride
|
|
Apoptosis
,
S1P Receptor
|
|
|
|
T3198L |
PRE-084 hydrochloride
|
|
Sigma receptor
|
|
PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay). |
|
T6303L |
CCT128930 hydrochloride
|
CCT128930 hydrochloride(885499-61-6 Free base) |
Apoptosis
,
Akt
,
PKA
,
mTOR
,
Autophagy
|
|
CCT128930 hydrochloride (CCT128930 hydrochloride) is a potent and selective inhibitor of AKT with IC50 of 6 nM. CCT128930 hydrochloride induces cell cycle arrest, DNA damage, and autophagy. CCT128930 hydrochloride has 28... |
|
T2170 |
SKF-96365 hydrochloride
|
SKF96365 |
Apoptosis
,
Potassium Channel
,
Calcium Channel
,
TRP/TRPV Channel
,
Autophagy
|
|
SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y cells. SKF-96365 hydrochloride can induce cytoprotective autopha... |
|
T72214 |
CTX-0294885 hydrochloride
|
|
|
|
CTX-0294885 hydrochloride is a broad-spectrum kinase inhibitor capable of capturing 235 kinases from MDA-MB-231 cells, including all members of the AKT family. This compound serves as a potent tool for analyzing kinome s... |
|
T72237 |
JBJ-09-063 hydrochloride
|
|
|
|
JBJ-09-063 hydrochloride is an EGFR inhibitor selective for mutants, demonstrating IC50 values of 0.147 nM, 0.063 nM, 0.083 nM, and 0.396 nM against EGFR L858R, EGFR L858R/T790M, EGFR L858R/T790M/C797S, and EGFR L747S, r... |
