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T67509 |
Cholesteryl Hemisuccinate
|
Cholesterol hydrogen succinate |
Apoptosis
,
DNA/RNA Synthesis
,
Topoisomerase
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Cholesteryl Hemisuccinate (Cholesterol hydrogen succinate) is a highly soluble cholesterol analogue often used in polar solutions for its hepatoprotective, anticancer and tumour growth inhibiting properties. Cholesteryl ... |
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T37853 |
Cholesteryl Lignocerate
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Others
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Cholesteryl lignocerate is a cholesterol ester that has been found in human meibum. Cholesteryl lignocerate can be hydrolyzed by cellular extracts from cultured human skin fibroblasts isolated from healthy individuals bu... |
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TF0106 |
Cholesteryl Hemisuccinate Tris Salt
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Apoptosis
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Cholesteryl Hemisuccinate Tris Salt is an acidic cholesteryl ester with hepatoprotective and anticancer activity.Cholesteryl hemisuccinate is a membrane stabilizer in dipalmitoylphosphatidylcholine liposomes containing C... |
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T38057 |
Cholesteryl Erucate
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Others
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Cholesteryl erucate, a cholesterol ester, serves as a standard for the quantification of cholesterol esters in human meibomian gland secretions. |
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T36731 |
Cholesteryl Heptadecanoate
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Others
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Cholesteryl heptadecanoate is a cholesterol ester (CE) formed by the condensation of cholesterol with heptadecanoic acid, a C-17 saturated fatty acid that does not occur in any natural animal or vegetable fat at high con... |
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T38056 |
Cholesteryl Arachidate
|
Cholesterol Arachidate |
Others
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Cholesteryl arachidate is a cholesterol ester that has been found in human meibum.[1][2] It has been used as an internal standard for the quantification of fatty acids in B. napus.[3] |
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T38046 |
Cholesteryl Homo-γ-Linolenate
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Others
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Cholesteryl homo-γ-linolenate is a cholesterol ester. It accumulates in the adrenal gland of rabbits fed a diet high in linolenic acid. Levels of cholesteryl homo-γ-linolenate are decreased and positively correlate with ... |
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T10807 |
Cholesteryl Linolenate
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Others
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Cholesteryl Linolenate is a human endogenous metabolite. |
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T35941 |
DC-Chol hydrochloride
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Cholesteryl 3β-N-(dimethylaminoethyl)carbamate hydrochloride,DC-Chol (hydrochloride),DC-Cholesterol hydrochloride,Cholesteryl 3β-N-(dimethylaminoethyl)carbamate |
Beta Amyloid
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DC-Chol hydrochloride(DC-Cholesterol hydrochloride) inhibited the formation of Aβ40 fibrils under appropriate experimental conditions and significantly inhibited amyloid formation from oxidized hCT in a dose-dependent ma... |
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T35405 |
(±)9-HODE cholesteryl ester
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Others
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(±)9-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL. Later studies determined that 15-LO from rabbit reticulocytes and human monoc... |
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T35404 |
(±)13-HODE cholesteryl ester
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Others
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(±)13-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL. Later studies determined that 15-LO from rabbit reticulocytes and human mono... |
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T35846 |
13(R)-HODE cholesteryl ester
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Others
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13(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid ... |
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T35853 |
9(S)-HODE cholesteryl ester
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Others
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9(S)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid p... |
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T35843 |
9(R)-HODE cholesteryl ester
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Others
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9(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid p... |
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T65074 |
Cholesteryl chloride
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Others
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Cholesteryl chloride is a useful organic compound for research related to life sciences. The catalog number is T65074 and the CAS number is 910-31-6. |
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T85217 |
Cholesteryl Palmitoleate
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Cholesterol Palmitoleate,16:1(9Z) Cholesterol ester,CE(16:1),16:1(9Z) CE |
Others
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Cholesteryl palmitoleate, a cholesterol ester, exhibits elevated plasma levels in ApoE-/- mice following exposure to cigarette smoke and in pediatric patients diagnosed with biliary atresia. It serves as a standard for i... |
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T85198 |
Cholesteryl Docosapentaenoate
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Others
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Cholesteryl docosapentaenoate, a cholesterol ester, exhibits increased levels in the liver, plasma, and skeletal muscle of acyl-CoA binding protein (ACBP) knockout mice relative to homozygous controls. |
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T85244 |
Cholesteryl 11,14-Eicosadienoate
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20:2 (11,14) Cholesterol ester,20:2 (11,14) CE |
Others
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Cholesteryl 11,14-eicosadienoate, a cholesterol ester, serves as a synthetic intermediate in the production of cholesterol (methyl) esters. |
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T84758 |
GL67
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N4-Spermine cholesteryl carbamate |
Others
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GL67 (N4-Spermine cholesteryl carbamate), a cationic lipid, facilitates the delivery of nucleic acid agents and vaccines, and is effective in gene transfection [1]. |
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T30040 |
Amphocil
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Amphotericin B cholesteryl sulfate |
Others
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Amphocil is used to treat patients with invasive fungal infection. |
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T84673 |
Glucosamine Cholesterol
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N-Cholesteryl succinyl glucosamine |
Others
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Glucosamine Cholesterol, also known as N-Cholesteryl succinyl glucosamine, is a lipid conjugate derived from glucosamine. It plays a crucial role in the development of lipid nanoparticles (LNPs) [1]. |
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T2499 |
Torcetrapib
|
CP-529414 |
CETP
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Torcetrapib (CP-529414) is a cholesteryl ester transfer protein (CETP) inhibitor that reduces the heterotypic transfer of cholesteryl ester from HDL to LDL and/or VLDL. Torcetrapib failed in phase III trials due to exces... |
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T41160 |
Lalistat 2
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Lipase
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Lalistat 2 is a selective inhibitor of lysosomal acid lipase with IC50 of 152 nM and exhibits no inhibition of human pancreatic lipase or bovine milk lipoprotein lipase (up to 10 μM). |
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T6262 |
Evacetrapib
|
LY2484595 |
CETP
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Evacetrapib (LY2484595) (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3. |
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T1928 |
Anacetrapib
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MK-0859 |
CETP
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Anacetrapib (MK-0859) (MK0859) is an effective, specific, reversible rhCETP and mutant CETP(C13S) inhibitor (IC50: 7.9 nM and 11.8 nM). Anacetrapib reduces the transfer of cholesteryl ester from HDL to LDL and/or VLDL th... |
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T6048 |
Dalcetrapib
|
JTT-705,RO4607381 |
CETP
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Dalcetrapib (RO4607381), a rhCETP inhibitor (IC50=0.2 μM), increases the plasma HDL cholesterol. |
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T82730 |
Cholesterylamine
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Others
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Cholesterylamine, a cationic lipid, can be incorporated into PLGA to create particles with a charged surface, facilitating its use in drug delivery systems and in the research of autoimmune diseases and allergies [1]. |
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T124183 |
7-Oxocholesteryl acetate
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Others
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7-Oxocholesteryl acetate is a useful organic compound for research related to life sciences and the catalog number is T124183. |
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T28225 |
Obicetrapib
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TA8995,AMG899,Obicetrapib (free base),AMG 899,AMG-899,Obicetrapib,TA-8995 |
CETP
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Obicetrapib (AMG-899) is an inhibitor of cholesteryl ester transfer protein. |
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T23550 |
YM-750
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YM 750 |
Acyltransferase
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YM-750 is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), with an IC50 value of 0.18 μM. ACAT is an enzyme that catalyzes the conversion of cholesterol and long-chain fatty-acyl-coenzyme A into cholest... |
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T68416 |
DRL-17822
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Others
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DRL-17822 is a Cholesteryl Ester Transfer Protein (CETP) inhibitor. |
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T14976 |
CKD-519
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Others
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CKD-519 is a selective inhibitor of cholesteryl ester transfer protein (CETP). It inhibits CETP-mediated transfer of cholesteryl ester in human serum (IC50: 2.3 nM). |
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T68265 |
PF-04445597
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Others
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PF-04445597 is a potent, orally bioavailable inhibitor of cholesteryl ester transfer protein (CETP). |
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T39137 |
CETP-IN-4
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Others
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CETP-IN-4 is a cholesteryl ester transfer protein (CETP) inhibitor. |
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T69672 |
MK-825
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Others
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MK-825 is a cholesteryl ester transfer protein (CETP) inhibitor. |
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T36139 |
BMS-795311
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Others
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Potent cholesteryl ester transfer protein (CETP) inhibitor (IC50 = 4 nM in an enzyme-based scintillation proximity assay). Inhibits cholesteryl ester transfer and increases HDL-C levels in vivo. Orally bioavailable.
Qiao... |
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T26548 |
Acaterin
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Others
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Acaterin, an inhibitor of acyl-CoA: cholesterol acyltransferase (ACAT), inhibits synthesis of cholesteryl ester in macrophage J774. |
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T68504 |
Obicetrapib calcium
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Others
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Obicetrapib calcium is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors substantially increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may have a possible beneficial... |
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T68505 |
Obicetrapib sodium
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Others
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Obicetrapib sodium is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors substantially increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may have a possible beneficial ... |
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T13079 |
TAP311
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CETP
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TAP311 is an inhibitor of cholesteryl ester transfer protein (CETP)(IC50 of 62 nM). |
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T38908 |
MK-8262
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Others
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MK-8262, an orally active and potent cholesteryl ester transfer protein (CETP) inhibitor (IC 50 = 53 nM, log D = 5.3), is a bistrifluoromethyl analogue that shows promise in research related to high-density lipoprotein (... |
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T68503 |
Obicetrapib potassium
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Others
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Obicetrapib potassium is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors substantially increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may have a possible benefici... |
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T84566 |
13(S)-HOTrE
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Others
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13(S)-HOTrE, the 15-lipoxygenase (15-LO) metabolite of linolenic acid, is present in cell membranes and as a cholesteryl ester in atherosclerotic lesions, as well as in the biomembranes of soybeans subjected to 15-LO. |
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T35603 |
Oleic Acid-2,6-diisopropylanilide
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Others
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AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol. Oleic acid-2,6-diisopropylanilide is an inhibitor of acylCoA:cholesterol ac... |
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T36567 |
DPPP
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DPPP is a probe that reacts stoichiometrically with hydroperoxides to yield the fluorescent molecule diphenyl-1-pyrenylphosphine oxide (DPPP-O). Plasma levels of lipid hydroperoxides of phosphatidylcholine, phosphatidyle... |
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T37554 |
Oleyl Anilide
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Others
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AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol. Oleyl analide (OA) is a weak inhibitor of acylCoA:cholesterol acyltransfera... |
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T36830 |
9-Nitrooleate
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Others
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Nitrated unsaturated fatty acids, such as 10- and 12-nitrolinoleate , cholesteryl nitrolinoleate, and nitrohydroxylinoleate, represent a new class of endogenous lipid-derived signalling molecules. LNO2 isomers serve as p... |
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T28290 |
Pactimibe
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CS 505,CS-505,CS505,Pactimibe free base |
Others
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Pactimibe is a ACAT inhibitor. It has anti-atherosclerotic activity. |
