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T11420 |
GLUT4 activator 1
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Others
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GLUT4 activator 1 is a potent glucose transporter type 4 (GLUT4) translocation activator (EC50: 0.14 μM). |
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T61695 |
GLUT4-IN-2
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GLUT4-IN-2, a selective inhibitor specifically targeting GLUT4, demonstrates potent antitumor activity with IC50 values of 6.8 μM for GLUT4 and 11.4 μM for GLUT1. It effectively induces cell apoptosis and arrests the cel... |
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T9558 |
KL-11743
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transporter
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KL-11743 specifically blocks glucose metabolism, triggering an acute collapse in NADH pools and a striking accumulation of aspartate, indicating a dramatic shift toward oxidative phosphorylation in the mitochondria. |
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TP1993L |
M617 acetate
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Neuropeptide Y Receptor
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M617 acetate is a selective agonist of galanin receptor 1 (GAL1). M617 acetate acts through central GAL1, promotes GLUT4 expression, and enhances GLUT4 content in the cardiac muscle of type 2 diabetic rats. The Ki values... |
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T33412 |
MitoPQ
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MitoParaquat |
Glucokinase
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transporter
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MitoPQ (MitoParaquat) is a mitochondria-targeted small molecule compound that selectively enhances mitochondrial superoxide and hydrogen peroxide levels and inhibits insulin-stimulated glucose uptake and translocation of... |
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T3713 |
BAY-876
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transporter
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BAY-876 is an orally active and selective inhibitor of glucose transporter 1 (GLUT1, IC50= 2 nM). BAY-876 exhibits >130-fold more selective for GLUT1 than GLUT2, GLUT3, and GLUT4. BAY-876 also inhibits glycolytic metabol... |
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T8616 |
Fasentin
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N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide |
transporter
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Fasentin (N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide) is an inhibitor of GluT1. |
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TP2312 |
MOTS-c(Human) Acetate（1627580-64-6 free）
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Others
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AMPK
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MOTS-c(Human) Acetate is a mitochondrial-derived peptide. MOTS-c(human) acetate induces the accumulation of AMP analog AICAR, increases activation of AMPK and expression of its downstream GLUT4. MOTS-c(human) acetate ind... |
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T8732 |
CTPI-2
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Others
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Mitochondrial Metabolism
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CTPI-2 is an inhibitor of mitochondrial citrate carrier SLC25A1 with(KD : 3.5 μM). CTPI-2 inhibits glycolysis, PPARγ, and its downstream target the glucose transporter GLUT4. CTPI-2 exhibits anti-tumor activity.CTPI-2 ha... |
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T75817 |
M617 TFA
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M617 TFA, a selective galanin receptor 1 (GAL1) agonist, exhibits dissociation constants (Kis) of 0.23 nM for GAL1 and 5.71 nM for GAL2. Through activation of GAL1, M617 TFA enhances GLUT4 expression and content in the c... |
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T76039 |
MOTS-c(human) acetate
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MOTS-c(human) acetate, a mitochondrial-derived peptide, induces the accumulation of AMP analog AICAR, enhances AMPK activation, and upregulates its downstream target, GLUT4. This compound promotes glucose uptake and enha... |
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T82252 |
GTPγS tetralithium
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GTPγS (tetralithium) is a G-protein activator known for its role in preventing proteolytic degradation of proteins, facilitating tyrosine kinase-dependent GLUT4 translocation, stimulating phospholipases, and promoting ac... |
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T36142 |
10-PAHSA
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10-PAHSA is a newly identified endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs). It is a FAHFA in which palmitic acid is esterified to 10-hydroxy stearic acid. A... |
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T71981 |
Gliclazide-d4
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Gliclazide-d4 is intended for use as an internal standard for the quantification of gliclazide by GC- or LC-MS. Gliclazide is a sulfonylurea and an inhibitor of pancreatic β-cell ATP-sensitive potassium (KATP) channels. ... |
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T36590 |
9-PAHSA
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Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity. Structurally, these esters are comprise... |
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T35800 |
MD001
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MD001 is a dual agonist of peroxisome proliferator-activated receptor α (PPARα) and PPARγ.1 It binds to PPARα and PPARγ (Kds = 9.55 and 0.14 μM, respectively) but does not bind to PPARβ/δ at concentrations up to 500 μM. ... |
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T36586 |
12-PAHSA
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Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity. Structurally, these esters are comprise... |
