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T61762 |
Zika virus-IN-3
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Zika virus-IN-3 (Compd 7) is a Zika virus inhibitor, with an EC 50 of 3.4 μM [1]. |
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T61953 |
Zika virus-IN-2
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Zika virus-IN-2 (Compd 3) is a Zika virus inhibitor (EC 50= 7.4 μM). |
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T63586 |
Zika virus-IN-1
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Zika virus-IN-1 is an inhibitor of Zika virus (EC50: 1.56 μM). |
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T23004 |
ML-SA1
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Mucolipin synthetic agonist 1 |
Others
,
TRP/TRPV Channel
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ML-SA1 (Mucolipin synthetic agonist 1) is a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. The IC50 value of ML-SA1 against DENV... |
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T72051 |
LabMol-319
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Virus Protease
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LabMol-319 is a potent Zika virus (ZIKV) NS5 RdRp inhibitor with antiviral activity for the study of ZIKV virus. |
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T6826 |
Emricasan
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PF 03491390,IDN-6556 |
Influenza Virus
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Caspase
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Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties. Emricasan has anti-inflammatory and anti-apoptotic activity and can be used in the treatment of infections and liver failure, etc. Emricasan a... |
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T16325 |
NITD008
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7-Deaza-2'-C-acetylene-adenosine |
Others
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NITD008 (7-Deaza-2'-C-acetylene-adenosine) is a potent and selective adenosine nucleoside inhibitor.NITD008 is an adenosine nucleoside analog with broad-spectrum antiviral activity that inhibits dengue, animal cupripoxvi... |
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T25130 |
Azaribine
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2',3',5'-Tri-O-acetyl-6-azauridine,NSC 67239 |
Antiviral
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Azaribine (2;,3;,5;-Tri-O-acetyl-6-azauridine) is an orotate monophosphate decarboxylase (OMPD) inhibitor with broad-spectrum antiviral activity, inhibiting viral genome replication and gene transcription.Azaribine has b... |
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TNU0007 |
3'-Deoxy-3'-fluoroadenosine
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Nucleoside Antimetabolite/Analog
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3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue with a wide range of anti-tumor and anti-viral activity, and has inhibitory effects on tick-borne encephalitis virus (TBEV), Zika virus and West Nile virus (WNV... |
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T0265 |
Merbromin
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Mercury dibromofluorescein disodium salt |
Others
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Antibacterial
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Merbromin (Mercury dibromofluorescein disodium salt) is an organomercuric disodium salt compound and a fluorescein, used as a topical antiseptic for minor cuts and scrapes. |
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T69942 |
CN-716 HCl
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cn-716 is a novel Zika virus (ZIKV) NS2B-NS3pro protease inhibitor. |
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T81642 |
NS2B-NS3pro-IN-1
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Virus Protease
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NS2B-NS3pro-IN-1, a potent Zika Virus NS2B-NS3 protease inhibitor, exhibits an EC50 of 50 μM and is significant in the ZIKV replication cycle [1]. |
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T69416 |
JMX0207
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JMX0207 is a novel inhibitor of viral protease function, suppressing Zika virus Infection both In vitro and In vivo. |
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T69186 |
CP26
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CP26 is a novel inhibitor of ER-to-cytosol protein dislocation, exhibiting anti-dengue and anti-Zika virus activity. |
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T63125 |
Antiviral agent 19
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Antiviral agent 19 (Compound 3) is a selective inhibitor of Zika virus (EC50: 1.3 μM) with low cytotoxicity. |
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T64166 |
Antiviral agent 20
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Antiviral agent 20 (Compound 17b) is a selective inhibitor of Zika virus (EC50: 4.5 μM) and exhibits low cytotoxicity. |
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T14658 |
Bis-propargyl-PEG5
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Others
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Bis-propargyl-PEG5 serves as a PEG-based PROTAC linker, facilitating the synthesis of PROTACs. This chemical compound is particularly employed in the synthesis of carbohydrate receptors (SCRs) with anti-Zika activity[1]. |
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T72887 |
NS2B/NS3-IN-7
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NS2B/NS3-IN-7 is a highly potent inhibitor of the Zika virus NS2B-NS3 protease, possessing a Ki value of 2.33 nM. It effectively reduces the number of ZIKV-infected cells. |
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T73292 |
ZIKV-IN-3
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ZIKV-IN-3, a derivative of andrographolide, serves as a potent inhibitor of the Zika virus (ZIKV) NS5 methyl transferase (MTase), showcasing an IC50 of 18.34 μM. It effectively curtails ZIKV replication and infection, ma... |
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T80760 |
XSJ2-46
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Influenza Virus
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XSJ2-46, a 5'-amino NI analog, is an antiviral agent possessing anti-Zika virus properties and demonstrates reasonable inhibition of RNA-dependent RNA polymerases (RdRp), with an IC50 of 8.78 μM [1]. |
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T63131 |
ZIKV-IN-1
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ZIKV-IN-1 is a potent inhibitor of zika virus (EC50: 2.8 μM, EC90: 6.8 μM). zIKV-IN-1 has anti-ZIKV effects and low cytotoxicity. zIKV-IN-1 shows high affinity for the RdRp domain of ZIKV. |
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T67784 |
6-fluorinated-aristeromycin2c
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6-fluorinated inated-aristeromycin2c showed antiviral activity against heat virus, Zika virus and Sars coronavirus. |
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T82957 |
ASN 07115873
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ASN 07115873 is an anti-Zika virus (ZIKV) compound with an inhibitory concentration (IC50) of 189.2 picomolar (pM), suitable for antiviral research [1]. |
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T63495 |
CYP2C1/CYP2C19-IN-2
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CYP2C1/CYP2C19-IN-2 is a potent inhibitor of CYP2C9/CYP2C19 without liver toxicity or genotoxicity and can be used to study Zika virus (ZIKV) infection. |
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T81641 |
NS2B-NS3pro-IN-2
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Virus Protease
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Compound 11, also known as NS2B-NS3pro-IN-2, functions as an inhibitor of the Zika Virus NS2B-NS3 protease and exhibits antiviral properties at a concentration of 50 μM [1]. |
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T63496 |
CYP2C9/CYP2C19-IN-1
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CYP2C9/CYP2C19-IN-1 is a potent inhibitor of CYP2C9/CYP2C19 without liver toxicity or genotoxicity and can be used to study Zika virus (ZIKV) infection. |
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T73156 |
LabMol-301
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LabMol-301, a chemical compound, effectively inhibits NS5 RdRp and NS2B-NS3pro activity with IC50 values of 0.8 μM and 7.4 μM, respectively. Additionally, it exhibits cytoprotective effects, safeguarding against Zika vir... |
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T78618 |
NSC 288387
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Virus Protease
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NSC 288387, a pan-flavivirus MTase inhibitor, binds to the SAM-binding pocket and effectively inhibits Zika virus (ZIKV) with an IC50 of 0.2 μM, also preventing viral replication in cell culture [1]. |
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T70941 |
CLR01 sodium
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CLR01 is a molecular tweezer. CLR01 reduces aggregated, pathologic, and seeding-competent α-synuclein in experimental multiple system atrophy. CLR01 inhibits aberrant superoxide dismutase 1 (SOD1) self-assembly in vitro ... |
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T64067 |
ZIKV-IN-2
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ZIKV-IN-2 is a potent inhibitor of ZIKV NS5 methyltransferase (MTase) (IC50: 38.86 μM) and inhibits the replication and infection of ZIKV, which can be used to study Zika virus (ZIKV). |
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T21978 |
P-nitro-Pifithrin-α
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p-nitro-Pifithrin-α is a cell-permeable analog of pifithrin-α, a potent p53 inhibitor. It suppresses p53-mediated TGF-β1 expression in HK-2 cells and inhibits the activation of caspase-3 by Zika virus (ZIKV) strains. Mor... |
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T63337 |
CYP2C19-IN-1
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CYP2C19-IN-1 is a potent, non-genotoxic, non-hepatotoxic inhibitor of CYP2C19. CYP2C19-IN-1 inhibits RNA-dependent RNA polymerase (RdRP) (Ki: 6.16 μM) and can be used to study Zika virus (ZIKV) infection. |
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T82592 |
DEC-RVRK-CMK
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Decanoyl-Arg-Val-Arg-Lys-chloromethylketone |
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Decanoyl-Arg-Val-Arg-Lys-chloromethylketone (DEC-RVRK-CMK) is a small, synthetic, irreversible cell-permeable competitive inhibitor of furin that exhibits strong antiviral activity against Zika virus (ZIKV) and Japanese ... |
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T79334 |
Antiviral agent 36
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DNA/RNA Synthesis
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Antiviral agent 36 (compound 27), a potent inhibitor of both dengue (DENV) and Zika (ZIKV) viruses, demonstrates replication inhibition with EC50 values of 100 nM for ZIKV-FLR, 90 nM for ZIKV-HN16, 210 nM for DENV-2, and... |
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T80729 |
ZIKV-IN-6
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ZIKV-IN-6 (compound 22) acts as a direct inhibitor of the Zika virus (ZIKV) by binding to its RNA-dependent RNA polymerase (RdRp) and obstructing viral RNA synthesis mediated by the ZIKV NS5 protein. This compound also d... |
