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カタログ番号	製品名	別名	ターゲット
T11315	Fosmidomycin sodium salt	FR-31564 sodium salt	Antibiotic , Parasite
	Fosmidomycin sodium salt (FR-31564 sodium salt) is an anti-infective antibiotic with anti-malarial activity that inhibits both Gram-negative and Gram-positive bacteria.		Antibiotic , Parasite
T13083L	Tafenoquine Succinate	WR 238605 (Succinate)	Others
	Tafenoquine Succinate (WR 238605 (Succinate)) is an 8-aminoquinoline. and is an agent of anti-malarial prophylactic.		Others
T79535	Antimalarial agent 30		Parasite
	Antimalarial agent 30 has anti-Plasmodium berghei liver stage parasite activity and antimalarial activity for the study of malarial infections.		Parasite
T69567	UCB7362	GLXC-26743	Parasite
	UCB7362 (GLXC-26743) is an orally available and potent plasmepsin X (PMX) inhibitor with anti-malarial activity.UCB7362 inhibits parasite reproduction.		Parasite
T5493	Pyronaridine		Others
	Pyronaridine is an orally active, mannitol-containing anti-malarial compound that acts by interfering with the replication of the malaria parasite (Plasmodium) within red blood cells. Pyronaridine is often used in combin...		Others
T8826	3-AMINO-1,2,4-TRIAZINE		Others
	3-AMINO-1,2,4-TRIAZINE is an aromatic bioactive compound. It has been used to synthesize a variety of drugs, including the antifungal drug fluconazole, the anti-inflammatory drug ibuprofen and the anticancer drug paclita...		Others
T13083	Tafenoquine	WR 238605	Others
	Tafenoquine is an 8-aminoquinoline,and is an agent of anti-malarial prophylactic.		Others
T78967	Anti-inflammatory agent 40		Parasite
	Anti-inflammatory agent 40 is a promising, orally-active compound with anti-malarial and anti-inflammatory properties. It effectively inhibits carrageenan-induced paw swelling in vivo.		Parasite
T60411	Primaquine
	Primaquine is the generally available anti-malarial that prevents relapse in vivax and ovale malaria, and the potent gametocytocide in falciparum malaria [1] [2].
T73328	DHFR-IN-5
	DHFR-IN-5, an orally active and potent inhibitor of dihydrofolate reductase (DHFR), exhibits a K_i value of 0.54 nM against the quadruple mutant Plasmodium falciparum DHFR, demonstrating anti-malarial activity.
T83019	Antiproliferative agent-38
	Antiproliferative Agent-38 (COM 18), a tetracyclic compound, features a reactive ring nitrogen (likely the quinoline moiety) that resists N-alkylation. Despite its classification, it neither exhibits anti-malarial proper...
T61047	JMI-346
	JMI-346 can be used as an anti-malarial agent that inhibits the P. falciparum strains CQS (3D7) and CQR (RKL-9) growth with IC50 values of 13 μM and 33 μM. JMI-346 is a potent inhibitor of Plasmodium falciparum falcipain...
T78184	MMV009085
	MMV009085 is a potent inhibitor of the Plasmodium falciparum hexose transporter (Pf HT1), with potential as an anti-malarial agent. It also inhibits the human glucose transporter, demonstrating high potency with an IC50 ...
T62123	FNDR-20123
	FNDR-20123 is the first safe and effective anti-malarial HDAC inhibitor, acting on both Plasmodium falciparum HDAC (IC50: 31 nM) and human HDAC (IC50: 3 nM). FNDR-20123 inhibited HDAC1 (IC50: 25 nM), HDAC2 (IC50: 29 nM),...
T61572	FNDR-20123 free base
	FNDR-20123 free base, a pioneering and orally administered anti-malarial agent, acts as a Histone Deacetylase (HDAC) inhibitor, displaying potent efficacy with IC50 values of 31 nM for Plasmodium and 3 nM for human HDAC,...

Compounds

Fosmidomycin sodium salt

T11315

Synonym: FR-31564 sodium salt

Target: Antibiotic, Parasite

Tafenoquine Succinate

T13083L

Synonym: WR 238605 (Succinate)

Target: Others

Antimalarial agent 30

3-AMINO-1,2,4-TRIAZINE

Anti-inflammatory agent 40

Antiproliferative agent-38

カタログ番号	製品名	別名	ターゲット
TN6512	Tectol		Transferase , Parasite
	Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 3.44±0.20μM. It exhibited significant activity against human leukemia cell lines HL60 and CEM. Tectol may cause itchy dermatiti...		Transferase , Parasite
T4333	Quinine dihydrochloride	Quinine bimuriate	Others
	Quinine dihydrochloride (Quinine bimuriate) is a primary alkaloid of various species of Cinchona (Rubiaceae). It is also an antimalarial and muscle relaxant (skeletal).		Others
T2481	Ascomycin	FK520,Immunomycin,FR-900520	Phosphatase , Others , Antibiotic , Parasite , Antifungal
	Ascomycin (Immunomycin)(Immunomycin, FR-900520, FK520) is an ethyl analog of tacrolimus (FK506) with strong immunosuppressant properties.
T2895	Lupeol	Fagarasterol,Monogynol B,Clerodol,(3β,13ξ)-Lup-20(29)-en-3-ol,Farganasterol	Apoptosis , Androgen Receptor , Akt
	Lupeol (Monogynol B) is a novel androgen receptor inhibitor with anti-inflammatory and antioxidant activity.		Apoptosis , Androgen Receptor , Akt
T6631	Quinine hydrochloride dihydrate	Quinine HCl Dihydrate	Potassium Channel , Parasite
	Quinine hydrochloride dihydrate (Quinine HCl Dihydrate) is a white crystalline K+ channel blocker, used to treat malaria.		Potassium Channel , Parasite
T3006	Cinnamylideneacetic acid	Beta-Styrylacrylic acid,5-Phenyl-2,4-pentadienoic acid,5-Phenylpenta-2,4-dienoic acid	Others , Antibacterial
	Cinnamylideneacetic acid (Beta-Styrylacrylic acid) is used as Synthetic building block, anti-malarial agent.		Others , Antibacterial
T8229	5,7,3',4'-Tetramethoxyflavone		Antibacterial , Parasite , Antifungal
	5,7,3',4'-Tetramethoxyflavone (TMF), a prominent polymethoxyflavone (PMF) derived from M. exotica, displays a range of notable bioactivities. These include anti-malarial, anti-fungal, anti-mycobacterial, and anti-inflamm...		Antibacterial , Parasite , Antifungal
T1151	Roxithromycin	Roxl-150,RU-28965	ribosome , Antibacterial , Antibiotic
	Roxithromycin (RU-28965) is a semi-synthetic derivative of the macrolide antibiotic erythromycin with antibacterial and anti-malarial activities.		ribosome , Antibacterial , Antibiotic
T7962	Coumalic acid	Cumalic Acid	Others
	Coumalic acid (Cumalic Acid) can be prepared from malic acid. It can be used in the industrial production of spices, flavorings, and cosmetics. It serves as a polymer component as well as an active molecular scaffold wit...		Others
T20712	Conessine	Conessinum,Wrightine,Roquessine,Neriine,Konessin	Histamine Receptor
	Conessine (Conessinum), a steroidal alkaloid isolated from Holarrhena floribunda, interacts with the histamine H3 receptor and has anti-malarial activity.		Histamine Receptor
T8689	Chloroquine	CQ	SARS-CoV , TLR , HIV Protease , Antibiotic , Parasite , Autophagy
	Chloroquine is a Toll-like receptor inhibitor that inhibits autophagy. Chloroquine has anti-malarial and anti-inflammatory activity and is widely used in the treatment of malaria and rheumatoid arthritis. Chloroquine als...
TN3033	4'-Hydroxy-2,4-dimethoxychalcone		Antibacterial , Parasite , Antifungal
	4'-Hydroxy-2,4-dimethoxychalcone is a naturally occurring chalcone derivative from the herbal resin of the red geranium Dragon's Blood.4'-Hydroxy-2,4-dimethoxychalcone possesses a wide range of biological activities incl...		Antibacterial , Parasite , Antifungal
TN4462	Lupeol caffeate		Antifection
	Lupeol caffeate has anti-malarial activity.		Antifection
TQ0072	Warangalone	Scandenolone	PKA
	Warangalone is an anti-malarial compound that can inhibit the growth of both strains of parasite 3D7 (chloroquine-sensitive) and K1 (chloroquine-resistant) with IC50s of 4.8 μg/mL and 3.7 μg/mL, respectively.		PKA
T75447	Asperaculane B
	Asperaculane B, a fungal metabolite, exhibits anti-malarial activity by inhibiting Plasmodium falciparum transmission and its asexual development, with IC50 values of 7.89 µM and 3 µM, respectively. Additionally, it is n...
TN3507	Beta-Yohimbine		Adrenergic Receptor , Antifection
	Beta-Yohimbine has approximately twice as toxic as yohimbine and corynanthine about one fifth as toxic. Beta-yohimbine has alpha-1 and alpha-2 adrenoceptor blocking activities, it has cardiovascular effects. Beta-Yohimbi...		Adrenergic Receptor , Antifection
T75333	Quinine hemisulfate hydrate
	Quinine hemisulfate hydrate, an alkaloid extracted from the cinchona tree bark, serves as an anti-malarial agent and potassium channel inhibitor. It specifically targets and inhibits WT mouse Slo3 (K Ca 5.1) channel curr...

天然物製品

Tectol

TN6512

Synonym:

Target: Transferase, Parasite

Quinine dihydrochloride

T4333

Synonym: Quinine bimuriate

Target: Others

Ascomycin

T2481

Synonym: FK520,Immunomycin,FR-900520

Target: Phosphatase, Others, Antibiotic, Parasite, Antifungal

Lupeol

T2895

Synonym: Fagarasterol,Monogynol B,Clerodol,(3β,13ξ)-Lup-20(29)-en-3-ol,Farganasterol

Target: Apoptosis, Androgen Receptor, Akt

Quinine hydrochloride dihydrate

T6631

Synonym: Quinine HCl Dihydrate

Target: Potassium Channel, Parasite

Cinnamylideneacetic acid

T3006

Synonym: Beta-Styrylacrylic acid,5-Phenyl-2,4-pentadienoic acid,5-Phenylpenta-2,4-dienoic acid

Target: Others, Antibacterial

5,7,3',4'-Tetramethoxyflavone

T8229

Synonym:

Target: Antibacterial, Parasite, Antifungal

Roxithromycin

T1151

Synonym: Roxl-150,RU-28965

Target: ribosome, Antibacterial, Antibiotic

Coumalic acid

T7962

Synonym: Cumalic Acid

Target: Others

Conessine

T20712

Synonym: Conessinum,Wrightine,Roquessine,Neriine,Konessin

Target: Histamine Receptor

Chloroquine

T8689

Synonym: CQ

Target: SARS-CoV, TLR, HIV Protease, Antibiotic, Parasite, Autophagy

4'-Hydroxy-2,4-dimethoxychalcone

TN3033

Synonym:

Target: Antibacterial, Parasite, Antifungal

Lupeol caffeate

TN4462

Synonym:

Target: Antifection

Warangalone

TQ0072

Synonym: Scandenolone

Target: Adrenergic Receptor, Antifection

Quinine hemisulfate hydrate

T75333

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-04180	PfLDH Protein, P. falciparum, Recombinant (His)	P. falciparum	E. coli
	Plasmodium falciparum lactate dehydrogenase (PfLDH) is a key enzyme for energy generation of malarial parasites and is considered to be a potential antimalarial target. The ability of PfLDH- or PfIDEh-based immuno-PCR as...

PfLDH Protein, P. falciparum, Recombinant (His)

TMPY-04180

Species: P. falciparum

Expression System: E. coli

カタログ番号	製品名
L6620	Antiparasitic Natural Product Library		253 compounds
	A unique collection of 253 natural products with antiparasitic activity, a powerful tool for high throughput screening (HTS) and high content screening (HCS);

ライブラリー

Antiparasitic Natural Product Library

L6620

Compounds: 253