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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T67509 | Cholesteryl Hemisuccinate | Cholesterol hydrogen succinate | Apoptosis , DNA/RNA Synthesis , Topoisomerase |
Cholesteryl Hemisuccinate (Cholesterol hydrogen succinate) is a highly soluble cholesterol analogue often used in polar solutions for its hepatoprotective, anticancer and tumour growth inhibiting properties. Cholesteryl ... | |||
T38057 | Cholesteryl Erucate | ||
Cholesteryl erucate, a cholesterol ester, serves as a standard for the quantification of cholesterol esters in human meibomian gland secretions. | |||
T36731 | Cholesteryl Heptadecanoate | ||
Cholesteryl heptadecanoate is a cholesterol ester (CE) formed by the condensation of cholesterol with heptadecanoic acid, a C-17 saturated fatty acid that does not occur in any natural animal or vegetable fat at high con... | |||
T37853 | Cholesteryl Lignocerate | ||
Cholesteryl lignocerate is a cholesterol ester that has been found in human meibum. Cholesteryl lignocerate can be hydrolyzed by cellular extracts from cultured human skin fibroblasts isolated from healthy individuals bu... | |||
T38056 | Cholesteryl Arachidate | Cholesterol Arachidate | |
Cholesteryl arachidate is a cholesterol ester that has been found in human meibum.[1][2] It has been used as an internal standard for the quantification of fatty acids in B. napus.[3] | |||
TF0106 | Cholesteryl Hemisuccinate Tris Salt | Apoptosis | |
Cholesteryl Hemisuccinate Tris Salt is an acidic cholesteryl ester with hepatoprotective and anticancer activity.Cholesteryl hemisuccinate is a membrane stabilizer in dipalmitoylphosphatidylcholine liposomes containing C... | |||
T38046 | Cholesteryl Homo-γ-Linolenate | ||
Cholesteryl homo-γ-linolenate is a cholesterol ester. It accumulates in the adrenal gland of rabbits fed a diet high in linolenic acid. Levels of cholesteryl homo-γ-linolenate are decreased and positively correlate with ... | |||
T10807 | Cholesteryl Linolenate | Others | |
Cholesteryl Linolenate is a human endogenous metabolite. | |||
T35405 | (±)9-HODE cholesteryl ester | ||
(±)9-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL. Later studies determined that 15-LO from rabbit reticulocytes and human monoc... | |||
T35404 | (±)13-HODE cholesteryl ester | ||
(±)13-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL. Later studies determined that 15-LO from rabbit reticulocytes and human mono... | |||
T35941 | DC-Chol hydrochloride | Cholesteryl 3β-N-(dimethylaminoethyl)carbamate hydrochloride,DC-Chol (hydrochloride),DC-Cholesterol hydrochloride,Cholesteryl 3β-N-(dimethylaminoethyl)carbamate | Beta Amyloid |
DC-Chol hydrochloride(DC-Cholesterol hydrochloride) inhibited the formation of Aβ40 fibrils under appropriate experimental conditions and significantly inhibited amyloid formation from oxidized hCT in a dose-dependent ma... | |||
T35846 | 13(R)-HODE cholesteryl ester | ||
13(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid ... | |||
T35843 | 9(R)-HODE cholesteryl ester | ||
9(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid p... | |||
T35853 | 9(S)-HODE cholesteryl ester | ||
9(S)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid p... | |||
T65074 | Cholesteryl chloride | ||
Cholesteryl chloride is a useful organic compound for research related to life sciences. The catalog number is T65074 and the CAS number is 910-31-6. | |||
T30040 | Amphocil | Amphotericin B cholesteryl sulfate | |
Amphocil is used to treat patients with invasive fungal infection. | |||
T2499 | Torcetrapib | CP-529414 | CETP |
Torcetrapib (CP-529414) is a cholesteryl ester transfer protein (CETP) inhibitor that reduces the heterotypic transfer of cholesteryl ester from HDL to LDL and/or VLDL. Torcetrapib failed in phase III trials due to exces... | |||
T41160 | Lalistat 2 | Lipase | |
Lalistat 2 is a selective inhibitor of lysosomal acid lipase with IC50 of 152 nM and exhibits no inhibition of human pancreatic lipase or bovine milk lipoprotein lipase (up to 10 μM). | |||
T6262 | Evacetrapib | LY2484595 | CETP |
Evacetrapib (LY2484595) (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3. | |||
T1928 | Anacetrapib | MK-0859 | CETP |
Anacetrapib (MK-0859) (MK0859) is an effective, specific, reversible rhCETP and mutant CETP(C13S) inhibitor (IC50: 7.9 nM and 11.8 nM). Anacetrapib reduces the transfer of cholesteryl ester from HDL to LDL and/or VLDL th... | |||
T6048 | Dalcetrapib | JTT-705,RO4607381 | CETP |
Dalcetrapib (RO4607381), a rhCETP inhibitor (IC50=0.2 μM), increases the plasma HDL cholesterol. | |||
T82730 | Cholesterylamine | ||
Cholesterylamine, a cationic lipid, can be incorporated into PLGA to create particles with a charged surface, facilitating its use in drug delivery systems and in the research of autoimmune diseases and allergies [1]. | |||
T124183 | 7-Oxocholesteryl acetate | ||
7-Oxocholesteryl acetate is a useful organic compound for research related to life sciences and the catalog number is T124183. | |||
T28225 | Obicetrapib | TA8995,AMG899,Obicetrapib (free base),AMG 899,AMG-899,Obicetrapib,TA-8995 | CETP |
Obicetrapib (AMG-899) is an inhibitor of cholesteryl ester transfer protein. | |||
T23550 | YM-750 | YM 750 | Acyltransferase |
YM-750 is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), with an IC50 value of 0.18 μM. ACAT is an enzyme that catalyzes the conversion of cholesterol and long-chain fatty-acyl-coenzyme A into cholest... | |||
T14976 | CKD-519 | Others | |
CKD-519 is a selective inhibitor of cholesteryl ester transfer protein (CETP). It inhibits CETP-mediated transfer of cholesteryl ester in human serum (IC50: 2.3 nM). | |||
T68416 | DRL-17822 | ||
DRL-17822 is a Cholesteryl Ester Transfer Protein (CETP) inhibitor. | |||
T39137 | CETP-IN-4 | ||
CETP-IN-4 is a cholesteryl ester transfer protein (CETP) inhibitor. | |||
T68265 | PF-04445597 | ||
PF-04445597 is a potent, orally bioavailable inhibitor of cholesteryl ester transfer protein (CETP). | |||
T69672 | MK-825 | ||
MK-825 is a cholesteryl ester transfer protein (CETP) inhibitor. | |||
T36139 | BMS-795311 | ||
Potent cholesteryl ester transfer protein (CETP) inhibitor (IC50 = 4 nM in an enzyme-based scintillation proximity assay). Inhibits cholesteryl ester transfer and increases HDL-C levels in vivo. Orally bioavailable. Qiao... | |||
T26548 | Acaterin | ||
Acaterin, an inhibitor of acyl-CoA: cholesterol acyltransferase (ACAT), inhibits synthesis of cholesteryl ester in macrophage J774. | |||
T13079 | TAP311 | CETP | |
TAP311 is an inhibitor of cholesteryl ester transfer protein (CETP)(IC50 of 62 nM). | |||
T68505 | Obicetrapib sodium | ||
Obicetrapib sodium is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors substantially increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may have a possible beneficial ... | |||
T68504 | Obicetrapib calcium | ||
Obicetrapib calcium is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors substantially increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may have a possible beneficial... | |||
T68503 | Obicetrapib potassium | ||
Obicetrapib potassium is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors substantially increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may have a possible benefici... | |||
T38908 | MK-8262 | ||
MK-8262, an orally active and potent cholesteryl ester transfer protein (CETP) inhibitor (IC 50 = 53 nM, log D = 5.3), is a bistrifluoromethyl analogue that shows promise in research related to high-density lipoprotein (... | |||
T35603 | Oleic Acid-2,6-diisopropylanilide | ||
AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol. Oleic acid-2,6-diisopropylanilide is an inhibitor of acylCoA:cholesterol ac... | |||
T36567 | DPPP | ||
DPPP is a probe that reacts stoichiometrically with hydroperoxides to yield the fluorescent molecule diphenyl-1-pyrenylphosphine oxide (DPPP-O). Plasma levels of lipid hydroperoxides of phosphatidylcholine, phosphatidyle... | |||
T37554 | Oleyl Anilide | ||
AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol. Oleyl analide (OA) is a weak inhibitor of acylCoA:cholesterol acyltransfera... | |||
T36830 | 9-Nitrooleate | ||
Nitrated unsaturated fatty acids, such as 10- and 12-nitrolinoleate , cholesteryl nitrolinoleate, and nitrohydroxylinoleate, represent a new class of endogenous lipid-derived signalling molecules. LNO2 isomers serve as p... | |||
T28290 | Pactimibe | CS 505,CS-505,CS505,Pactimibe free base | |
Pactimibe is a ACAT inhibitor. It has anti-atherosclerotic activity. |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T19237 | Cholesteryl oleate | Oleoylcholesterol,Cholesterol Oleate,Cholesteryl cis-9-octadecenoate | Endogenous Metabolite |
Cholesteryl oleate (Cholesteryl cis-9-octadecenoate) is a cholesteryl ester. Cholesteryl oleate can be used to synthesize solid lipid nanoparticles which is a nanoparticle-based gene therapy approach. | |||
T5214 | Cholesteryl linoleate | CE(18:2(9Z,12Z)),Cholesterol Linoleate,Linoleic Acid cholesteryl ester | Others , Endogenous Metabolite |
Cholesteryl linoleate (Linoleic Acid cholesteryl ester) is a cholesterol ester found in LDL. Cholesteryl linoleate is transferred to the plasma membrane of macrophages and CHO cells expressing 15-lipoxygenase (15-LO) via... | |||
T5239 | Cholesteryl sulfate sodium | Cholesterol 3-Sulfate Sodium Salt,Sodium Cholesteryl Sulfate | Endogenous Metabolite , PKC |
Cholesteryl sulfate sodium (Sodium Cholesteryl Sulfate) is a sterol sulfate in human plasma. Cholesteryl sulfate sodium is a component of cell membrane and has a regulatory function. Cholesteryl sulfate sodium also activ... | |||
T5074 | Cholesteryl palmitate | Others , Endogenous Metabolite | |
Cholesteryl palmitic acid is a cholesteryl ester. A cholesteryl ester is an ester of cholesterol. Fatty acid esters of cholesterol constitute about two-thirds of the cholesterol in the plasma. Cholesterol is a sterol (a ... | |||
T2918 | Cholesteryl Acetate | Cholesterin acetate,Cholesterol acetate,Acebrochol | Others |
Cholesteryl Acetate is a cholesterol ester obtained from the esterification of the hydroxyl group of cholesterol with acetic acid. It functions as a metabolite in the human body and is both a cholesterol ester and an ace... | |||
TN6902 | Cholesteryl formate | 3beta-Acetoxy-cholest-5-ene | |
Cholesteryl formate (3beta-Acetoxy-cholest-5-ene), the first compounds to be isolated from red algae, is a cholesteryl ester. | |||
T8040 | Cholesterol myristate | Cholesteryl myristate,Cholesteryl tetradecanoate | Others , Potassium Channel , GABA Receptor , Endogenous Metabolite , AChR |
Cholesterol Myristate (Cholesteryl Myristate) is a natural steroid found in traditional Chinese medicine that interacts with various ion channels, including the GABAA receptor, nicotinic acetylcholine receptor, and the i... | |||
T19236 | Cholesteryl behenate | Cholesteryl docosanoate,Cholesterol behenate | Others |
Cholesteryl behenate is a standard in electrospray ionization tandem mass spectrometry for the analysis of cholesteryl esters and cholesterol. | |||
T0760 | Cholesterol | Cholesterin,Cholesteryl alcohol | Estrogen Receptor/ERR , MRP , Endogenous Metabolite , ROR |
Cholesterol (cholesteryl alcohol) is a natural product that is the major sterol in mammals and an agonist of estrogen-related receptor α (ERRα). Cholesterol is widely found in the cell membranes of animals and is also us... | |||
T10806 | Cholesteryl arachidonate | Others | |
Cholesteryl arachidonate is a human endogenous metabolite. | |||
TN5057 | Stachybotramide | LDL | |
Stachybotramide preferentially stimulate the plasma cholesteryl ester transfer protein (CETP)-mediated transfer of cholesteryl esters (CE) from high density lipoprotein (HDL) to both very low density lipoprotein (VLDL) a... | |||
TN2834 | 27-p-Coumaroyloxyursolic acid | Others | |
27-trans-p-Coumaroyloxyursolic acid and 27-cis-p-coumaroyloxyursolic acid show potent inhibitory activity in the acyl CoA cholesteryl acyl transferase (ACAT) assay. | |||
T75696 | Ilexoside XLVIII | ||
Ilexoside XLVIII, a triterpene saponin isolated from the aqueous extract of Ilex kudincha leaves [1], functions as an acyl CoA cholesteryl acyl transferase (ACAT) inhibitor. |
カタログ番号 | 製品名 | Species | Expression System |
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TMPH-03323 | LIPA Protein, Rat, Recombinant (His) | Rat | E. coli |
Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol. LIPA Protein, Rat, Recombinant (His) is expressed in E.... | |||
TMPH-01625 | LIPA Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol. LIPA Protein, Human, Recombinant (His) is expressed in ... | |||
TMPY-04813 | ACAT2 Protein, Rat, Recombinant (His) | Rat | E. coli |
Acyl-coenzyme A: cholesterol acyltransferase (ACAT) is an intracellular enzyme that produces cholesteryl esters in various tissues. In mammals, two ACAT genes (ACAT1 and ACAT2) have been identified. Together, these two e... | |||
TMPH-01626 | LIPA Protein, Human, Recombinant (GST) | Human | E. coli |
Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol. LIPA Protein, Human, Recombinant (GST) is expressed in ... | |||
TMPH-01623 | GBA Protein, Human, Recombinant (His & Myc & SUMO) | Human | E. coli |
Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the tu... | |||
TMPJ-01302 | ACAT2 Protein, Human, Recombinant (His) | Human | E. coli |
ACAT2 is a cytoplasmic enzyme which belongs to the thiolase family. ACAT2 takes part in lipid metabolism, lipoprotein assembly, catalyzing cholesterol esterification in mammalian cells. It is responsible for the synthesi... | |||
TMPH-01624 | GBA Protein, Human, Recombinant | Human | E. coli |
Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the tu... | |||
TMPY-03353 | CEL Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
CEL-maturity onset diabetes of the young (MODY), diabetes with pancreatic lipomatosis and exocrine dysfunction, is due to dominant frameshift mutations in the acinar cell carboxyl ester lipase gene (CEL). Bile-salt activ... |
カタログ番号 | 製品名 | ||
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L2510 | Lipid Metabolism Compound Library | 492 compounds | |
A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS). |