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T38238 |
2'-Deoxy-2'-fluorocytidine
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|
Nucleoside Antimetabolite/Analog
,
Influenza Virus
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|
2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine can act synergistically with T705 to increase the potency o... |
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T7596 |
Firocoxib
|
ML 1785713 |
COX
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|
Firocoxib (ML 1785713) is a selective non-steroidal inhibitor of cycooxygenase-2 (COX-2) (IC50 of 0.13 μM), with anti-inflammatory for use in dogs and horses. |
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T38236 |
2′-Deoxy-2′-fluoroguanosine
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|
Nucleoside Antimetabolite/Analog
,
Influenza Virus
|
|
2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM). 2'-Deoxy-2'-fluoroguanosine is an inhibitor of influenza virus replication in the upper respirator... |
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T1531 |
Mometasone furoate
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Sch32088 |
Glucocorticoid Receptor
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|
Mometasone furoate (Sch32088) is a pregnadienediol derivative ANTI-ALLERGIC AGENT and ANTI-INFLAMMATORY AGENT that is used in the management of ASTHMA and ALLERGIC RHINITIS. It is also used as a topical treatment for ski... |
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T0059 |
Diphenylpyraline hydrochloride
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4-Diphenylmethoxy-1-methylpiperidine hydrochloride |
Histamine Receptor
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Diphenylpyraline hydrochloride (4-Diphenylmethoxy-1-methylpiperidine hydrochloride) is used in the treatment of Parkinsonism.It is a first-generation antihistamine with anticholinergic effects, functions as a dopamine re... |
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T21419 |
Diphenhydramine
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Debendrin,PM 255,PM255,Dabylen,Syntedril,PM-255 |
Histamine Receptor
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|
Diphenhydramine (Syntedril), a first-generation antihistamine possessing antiemetic, antitussive, anticholinergic, and sedative properties, is mainly used in the treatment of allergies. Diphenhydramine is also used in th... |
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T11281L |
FGI-106 tetrahydrochloride
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|
Virus Protease
,
HCV Protease
,
Influenza Virus
,
HIV Protease
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|
|
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T0005 |
Aspirin
|
Acetylsalicylate,Acetylsalicylic Acid,ASA |
Mitophagy
,
Virus Protease
,
COX
,
Autophagy
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|
Aspirin (Acetylsalicylic Acid) is a potent and selective inhibitor of COX with various pharmacological activities, such as anti-inflammation and pain relief. Aspirin is a histone deacetylase inhibitors to up-regulate cel... |
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T69324 |
Clofeverine hydrochloride
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|
|
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Clofeverine hydrochloride is the salt form of Clofeverine (free base), a highly selective relaxant for gastrointestinal smooth muscles with a beta-receptor stimulative nature. On isolated ileum, the inhibitory effect of ... |
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T69126 |
Clofeverine (free base)
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|
|
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Clofeverine (free base) is a highly selective relaxant for gastrointestinal smooth muscles with a beta-receptor stimulative nature. On isolated ileum, the inhibitory effect of clofeverine for spontaneous motility was com... |
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T9957 |
LASV inhibitor 3.3
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|
Virus Protease
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LASV inhibitor 3.3 is an inhibitor of Lassa fever virus (LASV) targeting lysosome-associated membrane protein 1 (LAMP1), a host factor that binds to the LASV glycoprotein (GP) during infection. |
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T1553 |
Chlorpheniramine maleate
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NCI-C55265,Chlorphenamine maleate |
Histamine Receptor
|
|
Chlorpheniramine maleate (NCI-C55265) is a histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. |
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T83975 |
Fenclozine Maleate
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S 1429 |
Histamine Receptor
|
|
Fenclozine Maleate (S 1429) is a potential histamine H1 receptor antagonist , which can be used to study fever, inflammation and pain. |
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T0118 |
Mizolastine
|
SL 850324 |
Histamine Receptor
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|
Mizolastine (SL 850324) (IC50= 47 nM) is a histamine H1-receptor antagonist.It is used in the treatment of allergic reactions such as hay fever (seasonal allergic rhinitis), hives. |
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T0785 |
Dexchlorpheniramine Maleate
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S-(+)-Chlorpheniramine maleate salt |
Dopamine Receptor
,
5-HT Receptor
,
Norepinephrine
,
Histamine Receptor
|
|
Dexchlorpheniramine Maleate (S-(+)-Chlorpheniramine maleate salt) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria. It is the pharmacologically active d... |
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T4563 |
Thonzylamine
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neohetramine |
Histamine Receptor
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|
Thonzylamine (neohetramine) is an antihistamine and anticholinergic drug. It is available as combination products with Clofedanol or Phenylephrine for temporary relief of symptoms of common cold, hay fever (allergic rhin... |
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T21369 |
Mecillinam
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Amdinocillin,Mecillinamum,Hexacillin,Coactin,Penicillin HX |
Antibacterial
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Mecillinam (Hexacillin), an extended-spectrum penicillin antibiotic, is considered to be active against Gram-negative bacteria by binding specifically to penicillin-binding protein 2 (PBP2). It is used primarily to treat... |
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T21390 |
Fexofenadine
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Carboxyterfenadine,Telfast,MDL 16.455,Allegra |
Histamine Receptor
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|
Fexofenadine (Carboxyterfenadine), an antihistamine pharmaceutical drug, is used to treat allergy symptoms, such as nasal congestion, hay fever, and urticaria. Compared to first-generation antihistamines, Fexofenadine is... |
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T1002 |
Etodolac
|
Ultradol,AY-24236,Etodolic acid,Lodine |
Retinoid Receptor
,
COX
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Etodolac (AY-24236) inhibits the activity of cyclooxygenase I and II, thereby preventing the formation of prostaglandin which is involved in the induction of pain, fever, and inflammation. Etodolac is a pyranocarboxylic ... |
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T0322 |
Fipexide
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Dopamine Receptor
,
AChR
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Fipexide (Attentil, Vigilor), a psychoactive drug of the piperazine chemical class, was developed in Italy in 1983. It was served as a nootropic drug in France and Italy, mainly for the therapy of senile dementia, but is... |
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T24077 |
G202-0362
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|
|
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G202-0362 is an antiviral agent against Rift Valley fever virus. It acts by blocking virus budding from the trans Golgi. |
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T11281 |
FGI-106
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Others
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FGI-106 is a potent, broad-spectrum inhibitor demonstrating activity against various viruses, including Ebola, Rift Valley Fever, and Dengue Fever, exhibiting EC50 values of 100 nM, 800 nM, and 400-900 nM, respectively. ... |
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T21247 |
Carbinoxamine
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Allergefon,(+-)-Carbinoxamine,Paracarbinoxamine |
|
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Carbinoxamine, an anticholinergic and antihistamine agent, is used for hay fever, angioedema, vasomotor rhinitis, mild urticaria, dermatographism and allergic conjunctivitis. It is a histamine antagonist, specifically an... |
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T27590 |
IHVR-11029
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IHVR 11029 |
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IHVR-11029 is a potent inhibitor of ER α-glucosidase. IHVR-11029 is active against multiple hemorrhagic fever viruses and efficiently disrupts the morphogenesis of a broad spectrum of enveloped viruses. |
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T15554 |
IHVR-19029
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|
Others
|
|
IHVR-19029 is an effective endoplasmic reticulum (ER) α-glucosidases I and II inhibitor (IC50: 0.48 μM for ER a-glucosidase I). IHVR-19029 efficiently blocks the replication of several hemorrhagic fever viruses, such as ... |
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T38957 |
2'-Deoxy-5'-O-DMT-2'-fluorouridine
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|
|
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2'-Deoxy-5'-O-DMT-2'-fluorouridine is a nucleoside analogue compound derived from 5'-O-DMTr-5-FUDR. This compound exhibits strong anti-yellow fever (YFV) activity. |
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T37870 |
Bz-Nle-Lys-Arg-Arg-AMC
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|
|
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Substrate for dengue virus NS2B-NS3 and yellow fever virus NS3 protease. The kcat/Km value of Bz-NleKRR-AMC for the dengue virus type 4 (DEN4) enzyme is > 800 fold higher than that of Boc-Gly-Arg-Arg-AMC, a widely used N... |
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T22983 |
Mizolastine dihydrochloride
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|
Others
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Mizolastine dihydrochloride is a histamine H1-receptor antagonist (IC50: 47 nM). It also used in the treatment of hay fever, hives, and other allergic reactions. |
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T69474 |
Naproxen ethyl ester
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|
|
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Naproxen ethyl ester is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same class as ibuprofen) that relieves pain, fever, swelling, and stiffness. It is a non-selective COX inhibitor. |
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T69267 |
Naproxen glucuronide
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|
|
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Naproxen glucuronide is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same class as ibuprofen) that relieves pain, fever, swelling, and stiffness. It is a nonselective COX inhibitor. |
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T27050 |
CM-10-18
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CM-1018 |
|
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CM-10-18 is a potent inhibitor of ER α-glucosidase. CM-10-18 demonstrated superior in vitro antiviral activity against representative viruses from four viral families causing hemorrhagic fever. CM-10-18 efficiently prote... |
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T70855 |
Favipiravir sodium
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|
|
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Favipiravir sodium is a selective inhibitor of viral RNA-dependent RNA polymerase with activity against many RNA viruses, influenza viruses, West Nile virus, yellow fever virus, foot-and-mouth disease virus as well as o... |
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T31396 |
Dexbrompheniramine maleate
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D-Brompheniramine,Brompheniramine d-,Dexbrompheniraminum,Disophrol,Drixoral |
|
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Dexbrompheniramine is an antihistamine with anticholinergic properties. It is used to treat allergic diseases such as hay fever or urticaria. It can compete with histamine for H1 receptor sites on effector cells of the g... |
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T69491 |
(E/Z)-Ensifentrine
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|
|
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(E/Z)-Ensifentrine is a potent and selective PDE3/4 inhibitor. (E/Z)-Ensifentrine acts as a long-acting inhibitor of the phosphodiesterase enzymes PDE-3 and PDE-4, producing both bronchodilator and antiinflammatory effec... |
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T70954 |
SP-187 HCl
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|
|
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SP-187, also known as N-9-DNJ and UV-4B, is an alpha-Glucosidase inhibitor potentially for the treatment of dengue fever and influenza infection. Proline-producing strains of Serratia marcescens were more osmotolerant t... |
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T75276 |
Dexbrompheniramine
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|
|
|
Dexbrompheniramine, an orally active H1 receptor antagonist (antihistamine), mitigates the impacts of the natural chemical histamine in the body. It is utilized in the study of hay fever and urticaria [1]. |
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T81309 |
RCB16007
|
|
|
|
RCB16007 is a Yellow Fever Virus (YFV) inhibitor that also demonstrates inhibitory action against the West Nile virus with an effective concentration (EC50) of 7.9 μM and a cytotoxic concentration (CC50) of 17 μM [1]. |
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T83121 |
Anatumomab mafenatox
|
ABR-214936 |
|
|
Anatumomab mafenatox (ABR-214936), a 73 KDa recombinant protein, targets the tumor-associated antigen 5T4 commonly expressed in malignancies. It is a conjugate comprising a modified form of SEA linked to a murine Fab. Th... |
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T36829 |
9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2
|
9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 |
|
|
9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (Meteneprost) is a potent analog of prostaglandin E2 with an extended half-life in vivo. In combination with various other prostaglandin derivatives, it results in the ... |
