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Search Results for " immune-modulating "

9

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7

天然化合物

13

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2

ライブラリー

カタログ番号 製品名 別名 ターゲット
T26582 AIM-102
AIM-102, a nonsteroidal, immune modulating, anti-inflammatory drug, is used potentially for the treatment of allergic asthma.
T82593 Debotansine
"Debotansine, an immunomodulator and antineoplastic [1], is a chemical compound with therapeutic applications in modulating the immune system and combating cancer."
T81114 Spns2-IN-1 LPL Receptor
Spns2-IN-1 is a potent Spns2 inhibitor, effectively impeding Spns2-dependent S1P transport with an IC50 value of 1.4±0.3 μM, crucial for modulating the immune response [1].
T74651 L-Inosine
L-Inosine, the L-configuration of Inosine, is an endogenous purine nucleoside derived from adenosine catabolism. It exhibits anti-inflammatory, antinociceptive (pain-relieving), immunomodulatory (immune system-modulating...
T80089 HCV-1 e2 Protein (554-569) (TFA)
HCV-1 e2 Protein (554-569) TFA, an antigenic segment of the hepatitis C virus envelope 2 (e2) protein, encompasses a potential N-glycosylation site implicated in modulating immune recognition of e2 [1].
T76748 Foralumab
Foralumab (NI-0401) is a powerful, orally administered humanized monoclonal antibody that specifically targets the CD3 receptor. By modulating immune responses in NSG mice reconstituted with human hematopoietic stem cell...
T74910 ODN 24888
ODN 24888, a guanine-modified inhibitory oligonucleotide (INH-ODN), effectively inhibits TLR7/TLR9-mediated signaling, reducing IFN-α levels and NF-κB activation, and suppressing IL-6 release. This compound plays a role ...
T76022 Chemerin-9 (149-157) (TFA)
Chemerin-9 (149-157) TFA is a potent CMKLR1 (chemokine-like receptor 1) agonist with anti-inflammatory properties. It activates phosphorylation of Akt and ERK and induces ROS production, beneficially modulating immune re...
T37644 Bengamide B
Potent inhibitor of NF-κB activation (IC50 = 85 nM); decreases IκBα phosphorylation. Attenuates LPS-induced nitric oxide production and expression of TNF-α, IL-6 and MCP. Suppresses proliferation of HeLa and HCT116 cell...
カタログ番号 製品名 別名 ターゲット
T8689 Chloroquine CQ SARS-CoV , TLR , HIV Protease , Antibiotic , Parasite , Autophagy
Chloroquine is a Toll-like receptor inhibitor that inhibits autophagy. Chloroquine has anti-malarial and anti-inflammatory activity and is widely used in the treatment of malaria and rheumatoid arthritis. Chloroquine als...
T0194 Chloroquine phosphate Chloroquine diphosphate,Aralen phosphate,Chingamin phosphate SARS-CoV , TLR , HIV Protease , Antibiotic , Parasite , Autophagy
Chloroquine phosphate (Aralen phosphate) is an aminoquinoline antimalarial and also is widely used as an autophagy inhibitor. Chloroquine also is an inhibitor of toll-like receptors (TLRs).
T7544 Fucoidan Others
Fucoidan is found in various species of brown seaweed and algae,with anticancer, antiviral, neuroprotective, immune-modulating.
T15705 Laminaran β-1,3-Glucan
Laminaran is a β-1,3-glucan isolated from brown algae, often serving as a typical ligand for Dectin-1. It possesses anti-cancer, immune-modulating, and radiation-protective properties. Laminaran can be catalyzed by gluca...
T4S1469 Cucurbitacin IIb Apoptosis , Others
1. Cucurbitacin IIb is one of the major active compounds in Hemsleyadine tablets which have been used for clinical treatment of bacillary dysentery, enteritis and acute tonsilitis. 2. Cucurbitacin IIb exhibits its anti-i...
T7009 Soyacerebroside II IL Receptor , Calcium Channel
Soyacerebroside II exhibits ionophoretic activity for Ca2+ ion. Soyacerebrosides I and II have modulating the cellular immune response effects, they show obvious inhibitory activity on IL-18 secretion in human peripheral...
TN3741 Cyclocurcumin TNF , ROS
Cyclocurcumin, a curcumin derivative, exhibits anticancer, anti-inflammatory, and immune-modulating abilities and is a potential compound for the treatment of rheumatoid arthritis as predicted by the MM-PBSA method. It m...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-04989 Galectin-9 Protein, Human, Recombinant (hFc) Human HEK293 Cells
LGALS9 (Galectin 9) is a Protein Coding gene. 6 alternatively spliced human isoforms have been reported. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix ...
TMPK-00829 Galectin-1 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Galectin 1(Gal-1), a β-galactoside binding mammalian lectin of 14KDa, is implicated in many signalling pathways, immune responses associated with cancer progression and immune disorders. Inhibition of human Gal-1 has bee...
TMPK-00022 Galectin-1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Galectin 1 (Gal-1), a β-galactoside binding mammalian lectin of 14KDa, is implicated in many signalling pathways, immune responses associated with cancer progression and immune disorders. Inhibition of human Gal-1 has be...
TMPH-03237 Orm1 Protein, Rat, Recombinant (His) Rat E. coli
Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Appears to function in modulating the activity of the immune system during the acute-phase reaction. Or...
TMPH-02989 ESAT-6 Protein, Mycobacterium bovis, Recombinant (His & Myc) Mycobacterium bovis E. coli
A secreted protein. Acts as a strong host T-cell antigen. Plays a number of roles in modulating the host's immune response to infection as well as being responsible for bacterial escape into the host cytoplasm. ESAT-6 Pr...
TMPH-03574 SdrE Protein, S. aureus, Recombinant (His) Staphylococcus aureus E. coli
Cell surface-associated calcium-binding protein which plays an important role in adhesion and pathogenesis. Contributes to the resistance to killing by innate immune components in blood and thus attenuates bacterial clea...
TMPH-00540 Epstein-Barr virus (strain GD1) LMP1 Protein (His) EBV P. pastoris (Yeast)
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several s...
TMPH-00542 Epstein-Barr virus (strain Raji) LMP1 Protein (His) EBV P. pastoris (Yeast)
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several s...
TMPY-03118 ORM2 Protein, Human, Recombinant (His) Human HEK293 Cells
ORM2 belongs to the calycin superfamily, lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic molecules such as steroids, ...
TMPH-00541 Epstein-Barr virus (strain AG876) LMP1 Protein (His & Myc) EBV E. coli
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several s...
TMPJ-00527 SP-D Protein, Human, Recombinant (His) Human HEK293 Cells
Surfactant Pulmonary-Associated Protein D (SP-D) is a 43 kDa member of the collectin family of innate immune modulators. Its principal components consist of a collagen-like region and a C-terminal carbohydrate recognitio...
TMPH-03733 Zaire ebolavirus (strain Kikwit-95) VP35 Protein (His & Myc) ZEBOV HEK293 Cells
Plays an essential role in viral RNA synthesis and also a role in suppressing innate immune signaling. Acts as a polymerase cofactor in the RNA polymerase transcription and replication complexes. Serves as nucleoprotein/...
TMPH-03732 Zaire ebolavirus (strain Kikwit-95) VP35 Protein (E. col, His & Myc) ZEBOV E. coli
Plays an essential role in viral RNA synthesis and also a role in suppressing innate immune signaling. Acts as a polymerase cofactor in the RNA polymerase transcription and replication complexes. Serves as nucleoprotein/...
カタログ番号 製品名
L2170 Immuno-Oncology Compound Library

449 compounds
A unique collection of 449 compounds acting on immune-oncology therapeutic targets can be used for high throughput and high content screening;
L6600 Anti-Gastroenteritis Natural Product Library

219 compounds
A unique collection of 219 natural products related to gastroenteritis for high throughput screening (HTS) and high content screening (HCS);