129
24
10
2
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T36422 | L-Lysine lactam (hydrochloride) | ||
L-lysine lactam is a building block.1,2It has been used in the synthesis of lysine sulfonamide HIV protease inhibitors, as well as bengamide derivatives within vitroanticancer activity. | |||
T36053 | D-Lysine lactam | ||
D-Lysine lactam is a chiral building block.1,2It has been used in the synthesis of a chiral antibiotic synthetic intermediate, as well as in the stereoselective synthesis of neurokinin (NK) receptor antagonists. 1.Kumar,... | |||
T37704 | Olanzapine Lactam Impurity | ||
Olanzapine lactam impurity is a potential impurity found in commercial preparations of olanzapine.1It is a degradation product formed by exposure to thermal or oxidative stress. 1.Baertschi, S.W., Brunner, H., Bunnell, C... | |||
T68462 | D-Ornithine lactam | ||
D-Ornithine lactam is a building block. It has been used in the synthesis of hepatitis C virus non-structural protein 5B inhibitors, as well as αVβ3 integrin receptor antagonists. | |||
T34138 | Prolyldiketopiperazine B | Homoleucyl-D-proline lactam, L-,L-Homoleucyl-D-proline lactam | |
Prolyldiketopiperazine B is a proline-based diketopiperazine. | |||
T71831 | L-Ornithine lactam hydrochloride | ||
L-Ornithine lactam is a synthetic intermediate. It has been used in the synthesis of dipeptidyl peptidase 4 (DPP-4) inhibitors, as well as signaling peptides. | |||
T8866 | GW779439X | Apoptosis , Antibacterial , CDK , Aurora Kinase | |
GW779439X is an inhibitor of CDK. | |||
T8507 | MAC-545496 | Antibacterial | |
MAC-545496 is a glycopeptide-resistance-associated protein R (GraR) inhibitor, is an antivirulence agent. | |||
T60050 | ANT3310 | Antibacterial | |
ANT3310 is an inhibitor of broad-spectrum covalent Serine β-Lactamase with IC50s ranging from 1 nM to 175 nM for AmpC, CTX-M-15, TEM-1, OXA-48, OXA-23, and KPC-2. ANT3310 can be used in studies about bacterial infection. | |||
T14979 | Clavulanate lithium | Clavulanic acid lithium | Antibacterial |
Clavulanate lithium (Clavulanic acid lithium) is an inhibitor of β-lactamase. | |||
T0234 | Methicillin sodium salt | Methicillin sodium,Meticillin sodium | Antibacterial , Antibiotic |
Methicillin sodium salt is the sodium salt form of methicillin, a semisynthetic beta-lactam penicillin antibiotic with beta-lactamase resistant activity. | |||
T4405 | Ceftibuten dihydrate | Sch-39720 dihydrate | Antibacterial , Antibiotic |
Ceftibuten dihydrate (Sch-39720 dihydrate) is the dihydrate form of ceftibuten, and is a third-generation cephalosporin with antibacterial activity. | |||
T6438 | Cefoselis Sulfate | FK 037 Sulfate,FK-037 | Antibacterial , Antibiotic |
Cefoselis Sulfate is a widely used beta-lactam antibiotic. | |||
T6471 | Dicloxacillin Sodium | Veracillin,BRL1702 Sodium,BRL1702,Sodium dicloxacillin | Others , Antibacterial , Antibiotic |
Dicloxacillin Sodium (BRL1702 Sodium) is a β-lactamase resistant penicillin similar to oxacillin and it has activity against gram-positive/negative aerobic and anaerobic bacteria. | |||
T20386 | Caprolactam | Others | |
Caprolactam is a natural product used in the manufacture of synthetic fibers of the polyamide type. | |||
T35427 | β-Lactamase-IN-2 | Antibacterial | |
β-Lactamase-IN-2 is an inhibitor of β-Lactamase with anti-microbial and anti-bacterial effects. | |||
T6179 | Moxalactam sodium salt | Latamoxef sodium,6059 S,Moxalactam Disodium,LY-127935,Antibiotic 6059S,Shiomarin,FestamoxinLy | Antibacterial , Antibiotic |
Moxalactam sodium salt (LY-127935) is an antibiotic compound more effective against Escherichia coli and Pseudomonas aeruginosathan cephalosporins. | |||
T38476 | Metallo β-lactamase ligand 1 | Antibacterial | |
Metallo β-lactamase ligand 1 is an inhibitor of class B β-lactamase exhibiting antibacterial activities. | |||
T19206 | β-Lactamase-IN-1 | 4-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one,beta-lactamase-IN-1 | Antibacterial |
β-Lactamase-IN-1 (4-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one) is a β-Lactamase inhibitor and targets the infection of Neisseria gonorrhoeae. | |||
T60282 | Metallo-β-lactamase-IN-3 | ||
Metallo-β-lactamase-IN-3 (compound 35) is a potent metallo-β-lactamases (MBL) inhibitor that has the potential to restore the activity of current β-lactam antibiotics and to offer an orthogonal strategy to the discovery ... | |||
T60694 | Metallo-β-lactamase-IN-4 | ||
Metallo-β-lactamase-IN-4 (compound 40) is a potent inhibitor of metallo-β-lactamases (MBL) with IC 50 values of 0.5 μM, 2.1 μM, and 3.3 μM for VIM-1, NDM-1 and IMP-7, respectively [1]. | |||
T60387 | β-Lactamase-IN-8 | ||
β-Lactamase-IN-8 (compound 20) is a potent and oral bioavailable broad-spectrum cyclic boronate β-lactamase inhibitor that can be used for researching antibacteria [1]. | |||
T72261 | Metallo-β-lactamase-IN-9 | ||
Metallo-β-lactamase-IN-9 (Compound 23) serves as a broad-spectrum inhibitor of metallo-beta-lactamases (MBL), exhibiting inhibition constants (IC50) of 35 nM for NDM-1, 269 nM for VIM-1, and 369 nM for IMP-1 [1]. | |||
T60239 | Metallo-β-lactamase-IN-6 | ||
Metallo-β-lactamase-IN-6 is a highly effective inhibitor of VIM-Type metallo-β-lactamase, demonstrating IC 50 values of 0.56 μM, 29.50 μM, and 5.78 μM for VIM-2, VIM-1, and VIM-5, respectively. In addition, Metallo-β-lac... | |||
T17299 | (-)-Indolactam V | Indolactam V | PKC |
(-)-Indolactam V is a PKC activator (Kis: 3.36 nM, 1.03 μM for η-CRD2 , γ-CRD2). (-)-Indolactam V also has the Kds are 5.5 nM (η-C1B), 7.7 nM (ε-C1B), 8.3 nM (δ-C1B), 18.9 nM (β-C1A-long), 20.8 nM (α-C1A-long), 137 nM (β... | |||
T60797 | β-Lactamase-IN-7 | ||
β-Lactamase-IN-7 (compound 14) effectively inhibit Klebsiella pneumoniae that is a potent inhibitor of VIM-Type metallo-β-lactamase with Ki values of 1.26 μM and 0.54 μM for VIM-1 and VIM-4, respectively [1]. | |||
T38956 | β-Lactamase-IN-5 | ||
β-Lactamase-IN-5, a β-lactamase inhibitor isolated from compound 720, holds significant potential for studying bacterial infections. | |||
T38955 | β-Lactamase-IN-4 | ||
β-Lactamase-IN-4 (WO2013149121A1, compound 708) is a potent β-lactamase inhibitor. It serves as a valuable tool in the investigation of bacterial infections. | |||
T60914 | Metallo-β-lactamase-IN-8 | ||
Metallo-β-lactamase-IN-8 (compound 17) is a potent, reversible and competitive broad-spectrum metallo-β-lactamases (MβLs) inhibitor with antibacterial activity. The IC50 values of Metallo-β-lactamase-IN-8 against L1, Imi... | |||
T60370 | Metallo-β-lactamase-IN-2 | ||
Metallo-β-lactamase-IN-4 (compound 40) is a potent metallo-β-lactamases (MBL) inhibitor with IC 50 values of 0.1 μM for VIM-1, 1.3 μM for NDM-1 and 5.0 μM for IMP-7, respectively [1]. | |||
T79435 | Metallo-β-lactamase-IN-11 | ||
Metallo-β-lactamase-IN-11 (compound 5f), a potent inhibitor of Metallo-β-lactamases (MBLs), demonstrates efficacy against the bacterial metallophyllactamase CphA with an IC50 value of 45 µM. At a concentration of 10 µM, ... | |||
T60494 | Metallo-β-lactamase-IN-7 | ||
Metallo-β-lactamase-IN-7 is a potent inhibitor of VIM -Type metallo-β-lactamase with IC 50 s of 0.019 μM, 13.64 μM, 0.38 μM for VIM-2, VIM-1 and VIM-5, respectively. Metallo-β-lactamase-IN-7 also enhances the antibacter... | |||
T124662 | Aristololactam II | ||
Aristololactam II is a useful organic compound for research related to life sciences and the catalog number is T124662. | |||
T126315 | Piperolactam D | ||
Piperolactam D is a useful organic compound for research related to life sciences. The catalog number is T126315 and the CAS number is 116084-93-6. | |||
T125605 | Aburatubolactam A | ||
Aburatubolactam A is a useful organic compound for research related to life sciences and the catalog number is T125605. | |||
T125112 | Stigmalactam | ||
Stigmalactam is a useful organic compound for research related to life sciences and the catalog number is T125112. | |||
T25117 | Atrolactamide | ||
Atrolactamide is an anticonvulsant. | |||
T67386 | Olanzapine Thiolactam Impurity | ||
(Z)-1-(4-(4-Methylpiperazin-1-yl)-2-thioxo-1H-benzo[b][1,4]diazepin-3(2H)-ylidene)propan-2-one is a useful organic compound for research related to life sciences and the catalog number is T67386. | |||
T61173 | Metallo-β-lactamase-IN-5 | ||
Metallo-β-lactamase-IN-5 (compound 5c) is a powerful inhibitor of metallo-β-lactamases (MBLs). Its inhibitory activity against MBLs NDM-1 and VIM-1 has been demonstrated. With an IC50 value of 45 μg/mL, Metallo-β-lactama... | |||
T125587 | Spirodihydrobenzofuranlactam IV | ||
Spirodihydrobenzofuranlactam IV is a useful organic compound for research related to life sciences. The catalog number is T125587 and the CAS number is 173220-03-6. | |||
T39865 | β-Lactamase-IN-6 | ||
β-Lactamase-IN-6 is a β-Lactamase inhibitor that shows high antibacetrial activity. | |||
T0827 | Cefsulodin sodium | Cefsulodine sodium,Sulcephalosporin | Antibacterial , Antibiotic |
Cefsulodin sodium (Sulcephalosporin) hydrate is a β lactam antibiotic. | |||
T6622 | Oxacillin sodium monohydrate | Stapenor monohydrate,Sodium oxacillin monohydrate,Methicillin,Bactocill monohydrate | Others , Antibacterial , Antibiotic |
Oxacillin sodium monohydrate (Stapenor monohydrate) is an antibacterial agent and is a narrow spectrum beta-lactam antibiotic of the penicillin class. | |||
T1495 | Cefaclor monohydrate | Cefaclor,Cefaclorum,Cefachlor | Antibacterial , Antibiotic |
Cefaclor monohydrate (Cefaclorum) is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. | |||
T5570 | Cephalothin | Cephalotin acid | Antibacterial , Antibiotic |
Cephalothin is a beta-lactam antibiotic, inhibits class C β-lactamase AmpC (Ki: 0.32 μM). | |||
T6385 | Amoxicillin Sodium | Clavulanate | Antibacterial , Antibiotic |
Amoxicillin Sodium (Clavulanate) is a moderate- spectrum, bacteriolytic, β-lactam antibiotic. | |||
T5024 | Cefotiam Hexetil Hydrochloride | Antibacterial , Antibiotic | |
Cefotiam Hexetil Hydrochloride is a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. | |||
T1631 | Sulbactam | CP45899 | Antibacterial , Antibiotic |
Sulbactam (CP45899) is a semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabol... | |||
T1001 | Dicloxacillin Sodium hydrate | Dicloxacillin sodium salt monohydrate,Dicloxacillin sodium monohydrate | Antibacterial , Antibiotic |
Dicloxacillin Sodium hydrate is a narrow-spectrum β-Lactam antibiotic of the penicillin class, used to treat infections caused by susceptible Gram-positive bacteria. | |||
T6582 | Mezlocillin Sodium | Baycipen | Antibacterial , Antibiotic |
Mezlocillin Sodium (Baycipen) is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T3S1227 | Aristolactam I | Aristolactam,Aristololactam I,Aristololactum | Apoptosis , Caspase |
1.Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristololactam I may be mediated by different mechanisms except TGF... | |||
TN4797 | Piperolactam C | PAFR , Antifection | |
Piperolactam C possesses anti-platelet aggregation activity in vitro. It can inhibit the growth of the fungi Cladosporium sphaerospermum and C. cladosporioides. | |||
T82970 | Aristolactam A III | Aristololactam A III | |
Aristolactam A III (Aristololactam A III) is an alkaloid that exhibits potential cytotoxic properties. It can be extracted from the herb Houttuyniae herba [1]. | |||
TJS1226 | 7-(deoxyadenosin-N(6)-yl)aristolactam I | Others | |
A natural compound from the herbs of Aristolochia debilis Sieb. et Zucc | |||
TN3443 | Aristolactam AII | PAFR | |
Aristolactam AII has cytotoxic activity, it also shows platelet aggregation inhibitory activity. | |||
TN4855 | Pterolactam | Others | |
Pterolactam is a natural product of Cibotium, Dicksoniaceae. The catalog number is TN4855 and the CAS number is 38072-88-7. Pterolactam can be used as a reference standard. | |||
T16846 | Sauristolactam | Saurolactam | Others |
Sauristolactam inhibits the receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclastogenesis and has the potential to inhibit osteoclast differentiation. Sauristolactam, a natural aristolactam isolated f... | |||
T81456 | Piperlactam S | ||
Piperlactam S, an active compound isolated from Piper kadsura, serves as a research agent for chronic inflammation [1]. | |||
T83229 | 9-Methoxyaristolactam I | ||
9-Methoxyaristolactam I, a natural product, is isolatable from the roots of Asarum sieboldii Miq. var. seoulense Nakai [1]. | |||
TN5251 | Walsuralactam A | Others | |
Walsuralactam A in the formula I, which is used as an active ingredient, and is used for treating and preventing the tumour. | |||
TN5059 | Stachybotrylactam | Others | |
Stachybotrylactam has toxicity. | |||
TN3445 | Aristolactam BIII | PAFR | |
Aristolactam BIII possesses anti-platelet aggregation activity in vitro, it also shows significant cytotoxic activity (IC50 values < 4 microg/mL) against P-388, HT-29 and A549 cell lines in vitro. | |||
TN3630 | Chartarlactam A | Others | |
Chartarlactam A shows antihyperlipidemic effects in HepG2 cells. | |||
TN3446 | Aristolactam FI | Others | |
Aristolactam FI shows platelet aggregation inhibitory activity.It is a potential cancer chemotherapeutic and chemopreventive agent. | |||
T75619 | Aristololactam IIIa | ||
Aristololactam IIIa demonstrates substantial inhibition of superoxide anion generation and elastase release, exhibiting IC50 values of 0.12 and 0.20 μg/mL, respectively [1]. | |||
TN6118 | Aristolactam IIIa N-β-glucoside | ||
Aristolactam IIIa N-β-glucoside is a natural product for research related to life sciences. The catalog number is TN6118 and the CAS number is 80311-26-8. | |||
TN3444 | Aristolactam BII | HIV Protease | |
Aristolactam BII exhibits antimicrobial and antiinflammatory activity, it shows significant activity towards DPPH radical scavenging and potent inhibitory effects against tyrosinase mushroom. Aristolactam BII also exerts... | |||
TN6034 | Aristolactam AIa | ||
Aristolactam AIa is a natural product for research related to life sciences. The catalog number is TN6034 and the CAS number is 97399-90-1. | |||
TL0017 | Aristolactam AIIIa | MAPK , CDK | |
Aristolactam AIIIa is a new type of Plk1 inhibitors, targeting the Polo Box domain (PBD), it has anti-tumor activity. Aristolactam IIIa shows inhibition of platelet aggregation induced by collagen or arachidonic acid. | |||
T1029 | Aztreonam | SQ-26,776 | Antibacterial , Antibiotic |
Aztreonam (SQ-26,776) is a monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum with bactericidal activity. | |||
T0814 | Ampicillin Trihydrate | NCI-C56086 | Antibacterial , Antibiotic |
Ampicillin Trihydrate (NCI-C56086), a broad-spectrum semisynthetic derivative of aminopenicillin, is a β-lactam antibiotic. | |||
T1505 | Imipenem monohydrate | N-Formimidoyl thienamycin monohydrate,Imipenem | Antibacterial , Antibiotic |
Imipenem monohydrate (Imipenem) is a broad-spectrum, semi-synthetic beta-lactam carbapenem derived from thienamycin, produced by Streptomyces cattleya. | |||
T0814L | Ampicillin | Amcill,D-(-)-α-Aminobenzylpenicillin,Aminobenzylpenicillin,Ampicillin acid | Antibacterial , Antibiotic |
Ampicillin (Aminobenzylpenicillin) is a semi-synthetic penicillin belonging to the β-lactam group of antibiotics. Ampicillin has bactericidal activity against a wide range of Gram-positive and Gram-negative bacteria. | |||
T8261 | Ceftazidime Pentahydrate | Antibacterial , Antibiotic | |
Ceftazidime is a β-lactam antibacterial agent which has demonstrated a broad spectrum of activity against Gram-positive and Gram-negative aerobic bacteria. |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPH-03488 | Metallo-beta-lactamase type 2 Protein, Serratia marcescens, Recombinant (His & Myc) | Serratia marcescens | E. coli |
Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring. | |||
TMPH-00587 | Beta-lactamase TEM Protein, E. coli, Recombinant (His & SUMO) | E. coli | E. coli |
TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins. TEM-3 and TEM-4... | |||
TMPH-00586 | Beta-lactamase TEM Protein, E. coli, Recombinant (His) | E. coli | Yeast |
TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins. TEM-3 and TEM-4... | |||
TMPH-02373 | Metallo-beta-lactamase type 2 Protein, Klebsiella pneumoniae, Recombinant (His) | Klebsiella pneumoniae | E. coli |
Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring. Does not confer resistance to the polymixin colistin or the fluoroquinol... | |||
TMPH-00584 | Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Broad spectrum beta-lactamase which confers resistance to penicillins, as well as first, second and third-generation cephalosporins. | |||
TMPH-03474 | Beta-lactamase CTX-M-2 Protein, Salmonella typhimurium, Recombinant | Salmonella typhimurium | E. coli |
Has cefotaxime-hydrolyzing activity. | |||
TMPH-03164 | Beta-lactamase OXA-10 Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) | Pseudomonas aeruginosa | E. coli |
Hydrolyzes both carbenicillin and oxacillin. | |||
TMPH-00585 | Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (Yeast, His) | E. coli | Yeast |
Broad spectrum beta-lactamase which confers resistance to penicillins, as well as first, second and third-generation cephalosporins. | |||
TMPH-00588 | Beta-lactamase Protein, E. coli, Recombinant (His & SUMO) | E. coli | E. coli |
This protein is a serine beta-lactamase with a substrate specificity for cephalosporins. | |||
TMPH-03165 | Beta-lactamase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) | Pseudomonas aeruginosa | E. coli |
Beta-lactamase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli with N-terminal 6xHis-SUMO tag. The predicted molecular weight is 56.7 kDa. Accession number: P24735 |
カタログ番号 | 製品名 | ||
---|---|---|---|
L9820 | Beta-Lactam Compound Library | 97 compounds | |
A unique collection of 97 beta-lactam compounds, can be used in HTS and HCS; | |||
L6500 | Microbial Natural Product Library | 550 compounds | |
A unique collection of 550 microbial natural products for high throughput screening (HTS) and high content screening (HCS); |