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カタログ番号 | 製品名 | 別名 | ターゲット |
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T9753 | LEI110 | Phospholipase | |
LEI110 is a potent Phospholipase A2, group XVI (PLA2G16) inhibitor with an Ki value of 20 nM. LEI110 is a selective pan-inhibitor of the HRASLS family of thiol hydrolases (i.e., PLA2G16, HRASLS2, RARRES3 and iNAT). | |||
T31976 | Glymidine sodium | Others | |
Glymidine sodium is a sulfonamide hypoglycemic agent which stimulates insulin secretion. | |||
T1162 | Acipimox | Olbemox,K-9321 | Others |
Acipimox (K-9321) is a niacin derivative and nicotinic acid analog with activity as a hypolipidemic agent. Acipimox has special application for the treatment of hyperlipidemia in non-insulin-dependent diabetic patients. | |||
T77621 | Z16078526 | p38 MAPK , Mitochondrial Metabolism | |
Z16078526 enhances thermogenesis in mice by inducing endogenous Ucp1 expression, promoting p38 MAPK phosphorylation, and stimulating lipolysis in primary mouse brown adipocytes. Additionally, it activates thermogenic gen... | |||
T1875 | Atglistatin | Lipase | |
Atglistatin is a highly effective, specific and competitive ATGL inhibitor with an IC50 of ~0.7 μM for inhibition of lipolysis in vitro, and no toxicity when the concentration up to 50 μM. | |||
T15432 | GSK256073 | GPR , Others | |
GSK256073 is an orally active GPR109A agonist. GSK256073 also is a long-lasting and non-flushing HCA2 (hydroxy-carboxylic acid receptor 2) full agonist (pEC50: 7.5). GSK256073 acutely improves glucose homeostasis via inh... | |||
T10830 | CL 316243 | Adrenergic Receptor | |
CL316243 is a highly potent selective agonist of β3-adrenoceptor, with a EC50 of 3 nM. CL316243 is an effective stimulant of adipocyte lipolysis and increases brown adipose tissue thermogenesis and metabolic rate. CL3162... | |||
T62656 | GPR81 agonist 1 | GPR | |
GPR81 agonist 1 is a potent and selective GPR81 agonist with high affinity for human and mouse GPR81.GPR81 agonist 1 inhibits lipolysis of differentiated 3T3-L1 adipocytes, improves insulin sensitivity and glycaemic cont... | |||
T73499 | NG-497 | NG497 | Lipase |
NG-497 is a selective, small molecule inhibitor of human adipose triglyceride lipase (ATGL) that targets the enzymatically active patatin-like structural domain of human ATGL.NG-497 binds ATGL in a hydrophobic lumen adja... | |||
TP1219 | Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate | ANP (1-28), human, porcineANP(1-28) | |
TP2267 | Lys-γ3-MSH(human) | Lys-γ3-MSH | Others |
Pro-opiomelanocortin (POMC) derived peptide that stimulates lipolysis | |||
T19338 | Gelucire 44/14 | Gelucire 14/44 | Others |
Gelucire 44/14 (Gelucire 14/44) acts as a nonionic surface-active excipient and improves fat absorption in rats with impaired lipolysis. | |||
T26935 | C108297 | C-108297,C 108297 | |
C108297 is a glucocorticoid receptor modulator. C108297 prevents both diet-induced obesity and inflammation. C108297 decreased food and fructose intake and increased lipolysis in white adipose tissue (WAT) and free fatty... | |||
T82732 | Cholecystokinin (1-21) | CCK-1-21 | |
Cholecystokinin (1-21) (CCK-1-21), a fragment of cholecystokinin (CCK), induces lipolysis in human adipose tissue [1]. | |||
T61464 | TRβ agonist 2 | ||
TRβ agonist 2 (Compound 1) is a highly potent agonist of TRβ. Moreover, it effectively reduces lipid accumulation in HepG2 cells and promotes lipolysis, offering comparable effects. With its promising attributes, TRβ ago... | |||
T75849 | Lys-γ3-MSH(human) TFA | ||
Lys-γ3-MSH(human) TFA, a melanocortin peptide originating from the C-terminal fragment of pro-opiomelanocortin (POMC), enhances the steroidogenic response of rat adrenal glands to adrenocorticotrophin (ACTH). It is a pot... | |||
T60925 | TRβ agonist 3 | ||
TRβ agonist 3 (Compound 3) is a potent TRβ agonist that is a new potential TRβ-selective thyromimetics. In vitro investigation, TRβ agonist 3 reduces lipid accumulation in HepG2 and promote lipolysis [1]. | |||
T72745 | Acipimox sodium | K-9321 sodium | |
Acipimox (K-9321) sodium, a nicotinic acid analogue, functions as an antilipolytic agent by stimulating leptin release, inhibiting lipolysis, and reducing systemic free fatty acids (FFAs) levels, thereby enhancing insuli... | |||
T27228 | E-3030 free acid | E-3030,E3030,E 3030 | |
E-3030 free acid is a peroxisome proliferator-activated receptor (PPAR) agonist. E-3030 decreased blood glucose, triglyceride, non-esterified fatty acids, and insulin levels and increased blood adiponectin levels. Trigly... |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T4S0227 | Sinensetin | Pedalitin permethyl ether | TNF , PGE Synthase |
Sinensetin (Pedalitin permethyl ether) is a methylated flavone found in certain citrus fruits. pocess potent antiangiogenesis and anti-inflammatory, sinensetin enhances adipogenesis and lipolysis. | |||
T19924 | Rhododendrol | Betuligenol,Frambinol | Others |
Rhododendrol (Frambinol) is a melanin synthesis and acts by preventing high-fat diet-induced elevation in body weight and increasing lipolysis in white adipocytes in male mice. Rhododendrol can be used as the lightening/... | |||
T8209 | Saikosaponin b3 | Others | |
Saikosaponin B3 shows some analgesic effect. | |||
T3S0964 | Thermopsoside | Chrysoeriol-7-O-glucoside | Others |
Chrysoeriol-7-O-glucoside can strongly inhibit the classical pathway of the complement system.Chrysoeriol-7-O-d-glucoside and luteolin-7-O-d-glucoside can inhibit palmitic acid uptake into small intestinal brush border m... | |||
T81013 | Tert-OMe-byakangelicin | ||
Tert-OMe-byakangelicin is a coumarin known to potentiate adrenaline-induced lipolysis and impede insulin-mediated triglyceride synthesis from glucose in adipocytes [1]. | |||
T79949 | Foenumoside B | PPAR | |
Foenumoside B, a triterpene saponin extracted from Lysimachia foenum-graecum, stimulates AMPK signaling, suppresses PPARγ-induced adipogenesis, and promotes lipolysis, shifting lipid metabolism. This compound is utilized... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPJ-01010 | PLA2G16 Protein, Human, Recombinant (His) | Human | E. coli |
Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in the regulation of differenti... | |||
TMPH-02420 | APOC3 Protein, Cynomolgus, Recombinant (His & SUMOstar) | Cynomolgus | Yeast |
Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density... | |||
TMPH-02516 | APOC3 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density... | |||
TMPY-03117 | Zinc Alpha 2 Glycoprotein/AZGP1 Protein, Human, Recombinant (His) | Human | HEK293 |
Alpha-2-glycoprotein, also known as AZGP1, belongs to the MHC class I family. It can be detected in body fluids such as serum, sweat, and seminal and breast cyst fluids. It has been shown that alpha-2-glycoprotein can st... | |||
TMPH-01768 | VGF Protein, Human, Recombinant (GST & His & Myc) | Human | E. coli |
Secreted polyprotein that is packaged and proteolytically processed by prohormone convertases PCSK1 and PCSK2 in a cell-type-specific manner. VGF and peptides derived from its processing play many roles in neurogenesis a... | |||
TMPY-02081 | PDE2A Protein, Human, Recombinant (aa 215-900, His) | Human | Baculovirus-Insect Cells |
cGMP-dependent 3',5'-cyclic phosphodiesterase, also known as cyclic GMP-stimulated phosphodiesterase and PDE2A, is a peripheral membrane protein that belongs to the cyclic nucleotide phosphodiesterase family and PDE2 sub... | |||
TMPY-02167 | Complement Factor D/CFD Protein, Mouse, Recombinant (His,HEK293) | Mouse | HEK293 |
Complement factor D, also known as Adipsin, C3 convertase activator, Properdin factor D and CFD is a secreted protein which belongs to thepeptidase S1 family. CFD / Adipsin contains onepeptidase S1 domain. Complement ... | |||
TMPY-02183 | Complement Factor D/CFD Protein, Human, Recombinant (His) | Human | HEK293 |
Complement factor D, also known as Adipsin, C3 convertase activator, Properdin factor D and CFD is a secreted protein which belongs to thepeptidase S1 family. CFD / Adipsin contains onepeptidase S1 domain. Complement ... | |||
TMPH-03500 | IL-6 Protein, Sheep, Recombinant (GST) | Sheep | E. coli |
Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-sign... | |||
TMPH-03208 | IL-6 Protein, Rabbit, Recombinant (His) | Rabbit | Yeast |
Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-sign... |