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Search Results for " osteogenesis "

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7

阻害剤

4

天然化合物

35

リコンビナントタンパク質

2

ライブラリー

カタログ番号 製品名 別名 ターゲット
T7469 Alendronic Acid alendronate Others
Alendronic Acid (alendronate) is a nonhormonal medication used for osteoporosis, osteogenesis imperfecta, and several other bone diseases.
T40498L Dentonin acetate Dentonin acetate (400090-20-2 Free base) Others
Dentonin acetate enhances osteogenesis and facilitates immature adherent cell survival. Dentonin acetate, a synthetic fragment derived from MEPE, can be used in phosphate homeostasis and bone metabolism studies.
T37603L Osteogenic Growth Peptide (10-14) acetate Osteogenic Growth Peptide (10-14) acetate(105250-85-9 Free base) Src
Osteogenic Growth Peptide (10-14) acetate (Osteogenic Growth Peptide) is a Src inhibitor and an effective mitogen and stimulator of osteogenesis and hematopoiesis. Osteogenic Growth Peptide (10-14) acetate is responsible...
T13794 Neridronate Others
Neridronate is an aminobisphosphonate,for the treatment of osteogenesis imperfecta (OI) and Paget’s disease of bone (PDB).
T40498 Dentonin AC-100
Dentonin (AC-100) is a synthetic fragment derived from MEPE that enhances osteogenesis by promoting osteoprogenitor adhesion and facilitating the survival of immature adherent cells. It does not have a significant effect...
T81173 Setrusumab BPS 804
Setrusumab (BPS 804) is a fully humanized monoclonal antibody targeting sclerostin, effectively enhancing bone strength. It is utilized in research on Osteogenesis Imperfecta (OI) and cancer [1].
T83848 VnP-16 TFA
VnP-16, a synthetic peptide fragment mirroring amino acids 270-281 of vitronectin (a multifunctional glycoprotein involved in cell attachment, migration, and spreading), promotes attachment and spreading of isolated huma...
カタログ番号 製品名 別名 ターゲット
TN2081 Maohuoside A MAPK
Maohuoside A promotes osteogenesis of rat mesenchymal stem cells via BMP and MAPK signaling pathways.
T6S1966 Curculigoside Curculigoside A Antioxidant , NF-κB , JAK , STAT
1. Curculigoside (Curculigoside A) can prevent bone loss , improve osteogenesis and inhibit osteoclastogenesis of hAFSCs, suggesting its potential use to regulate hAFSC osteogenic differentiation for treating bone disord...
TN5447 Apigenin 7-O-methylglucuronide Apigenin-7-O-β-D-glucuronide methyl ester
Apigenin 7-O-methylglucuronide did not affect GAG level or secretion, may potentially be used in osteogenesis imperfecta (OI) type I pharmacotherapy in patients with normal GAG content. Apigenin 7-O-methylglucuronide whi...
TN1778 Isoformononetin IL Receptor , Antifection
Isoformononetin shows fungitoxic activity against Cladosporium sphaerospermum; it also has immunomodulatory activity, it inhibits the differentiation of Th17 cells and B-cell lymphopoesis to promote osteogenesis in estro...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-02626 FGF-18 Protein, Human, Recombinant (His) Human HEK293
Fibroblast growth factor 18 (FGF18) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes...
TMPY-00423 FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc) Human HEK293
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-03357 FGFR2 Protein, Mouse, Recombinant (hFc) Mouse HEK293
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-00972 FGFR2 Protein, Human, Recombinant (His & hFc) Human HEK293
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-00875 Leptin Protein, Human, Recombinant Human E. coli
Leptin is one of the most important hormones secreted by adipocytes, as an adipokine that modulates multiple functions including energy homeostasis, thermoregulation, bone metabolism, endocrine, and pro-inflammatory immu...
TMPH-01016 GDF-10 Protein, Human, Recombinant (His) Human E. coli
Growth factor involved in osteogenesis and adipogenesis. Plays an inhibitory role in the process of osteoblast differentiation via SMAD2/3 pathway. Plays an inhibitory role in the process of adipogenesis.
TMPY-01930 Fetuin B Protein, Human, Recombinant (His) Human HEK293
Fetuin-B, also known as Fetuin-like protein IRL685 and FETUB, is a secreted protein which belongs to thefetuin family. Fetuin-B / FETUB contains twocystatin domains. Fetuin-B is a member of the fetuin family, part of ...
TMPY-01780 Fetuin B Protein, Mouse, Recombinant (His) Mouse HEK293
Fetuin-B, also known as Fetuin-like protein IRL685 and FETUB, is a secreted protein which belongs to thefetuin family. Fetuin-B / FETUB contains twocystatin domains. Fetuin-B is a member of the fetuin family, part of ...
TMPY-01380 Cyclophilin B Protein, Human, Recombinant (His) Human HEK293
PPIB is identified as a candidate gene for OI-IX. Osteogenesis imperfecta (OI) is an inherited disorder of connective tissue typically caused by defects in either COL1A1 or COL1A2. A number of other genes causative of th...
TMPH-02471 14-3-3 beta/alpha Protein, Mouse, Recombinant (E. coli, His) Mouse E. coli
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine moti...
TMPH-02472 14-3-3 beta/alpha Protein, Mouse, Recombinant (His) Mouse Yeast
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine moti...
TMPK-00386 FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region con...
TMPK-00390 FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region con...
TMPK-00387 FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region con...
TMPK-00385 FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi) Human HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region con...
TMPK-00389 FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi) Human HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region con...
TMPK-00384 FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi) Human HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region con...
TMPK-00388 FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi) Human HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region con...
TMPK-00686 FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His) Mouse HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region con...
TMPH-01017 BMP-4 Protein, Human, Recombinant (His) Human E. coli
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. Acts in concert with PTHLH/PTHRP to stimu...
TMPY-01415 FGF-18 Protein, Mouse, Recombinant (His) Mouse HEK293
Fibroblast growth factor 18 (FGF18) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes...
TMPH-00228 BMP-4 Protein, Bovine, Recombinant (GST) Bovine E. coli
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. Acts in concert with PTHLH/PTHRP to stimu...
TMPH-01700 SMAD3 Protein, Human, Recombinant (His) Human Baculovirus
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in t...
TMPH-01014 BMP-2 Protein, Human, Recombinant (His) Human E. coli
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including cardiogenesis, neurogenesis, and osteogenesis. Induces cartilage and bone formation. Initiates the canonical...
TMPJ-01294 SOST Protein, Mouse, Recombinant (His) Mouse Human Cells
Sclerostin (SOST) is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. Cerberus/DAN family members are putative BMP antagonists, and include Dan, Cerberus, Gre...
TMPY-03389 FGFR2 Protein, Mouse, Recombinant (His) Mouse HEK293
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-01228 FGFR2 Protein, Human, Recombinant (aa 1-377, His) Human HEK293
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-03504 CBFB Protein, Human, Recombinant (His) Human E. coli
CBFB is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and os...
TMPY-04390 FGFR2 Protein, Human, Recombinant (aa 400-821, His & GST) Human Baculovirus-Insect Cells
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-06321 FGFR2 Protein, Human, Recombinant (alpha(IIIb), His & Avi), Biotinylated Human HEK293
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-04273 FGFR2 Protein, Human, Recombinant (aa 1-378, His) Human HEK293
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-00351 FGFR2 Protein, Human, Recombinant (beta IIIc, His) Human HEK293
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-00802 Fetuin A Protein, Mouse, Recombinant (His) Mouse HEK293
Fetuin-A, also known as Alpha-2-HS-Glycoprotein (AHSG), belongs to the Fetuin family, is a plasma binding protein, and is more abundant in fetal than adult blood. It is involved in several functions, such as endocytosis,...
TMPY-00801 Fetuin A Protein, Human, Recombinant (His) Human HEK293
Fetuin-A, also known as Alpha-2-HS-Glycoprotein (AHSG), belongs to the Fetuin family, is a plasma binding protein, and is more abundant in fetal than adult blood. It is involved in several functions, such as endocytosis,...
TMPY-06375 Leptin Protein, Mouse, Recombinant (mFc) Mouse HEK293
Leptin is one of the most important hormones secreted by adipocytes, as an adipokine that modulates multiple functions including energy homeostasis, thermoregulation, bone metabolism, endocrine, and pro-inflammatory immu...
FGF-18 Protein, Human, Recombinant (His)
TMPY-02626
Species: Human
Expression System: HEK293
FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc)
TMPY-00423
Species: Human
Expression System: HEK293
FGFR2 Protein, Mouse, Recombinant (hFc)
TMPY-03357
Species: Mouse
Expression System: HEK293
FGFR2 Protein, Human, Recombinant (His & hFc)
TMPY-00972
Species: Human
Expression System: HEK293
Leptin Protein, Human, Recombinant
TMPY-00875
Species: Human
Expression System: E. coli
GDF-10 Protein, Human, Recombinant (His)
TMPH-01016
Species: Human
Expression System: E. coli
Fetuin B Protein, Human, Recombinant (His)
TMPY-01930
Species: Human
Expression System: HEK293
Fetuin B Protein, Mouse, Recombinant (His)
TMPY-01780
Species: Mouse
Expression System: HEK293
Cyclophilin B Protein, Human, Recombinant (His)
TMPY-01380
Species: Human
Expression System: HEK293
14-3-3 beta/alpha Protein, Mouse, Recombinant (E. coli, His)
TMPH-02471
Species: Mouse
Expression System: E. coli
14-3-3 beta/alpha Protein, Mouse, Recombinant (His)
TMPH-02472
Species: Mouse
Expression System: Yeast
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00386
Species: Human
Expression System: HEK293
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00390
Species: Human
Expression System: HEK293
FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00387
Species: Human
Expression System: HEK293
FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi)
TMPK-00385
Species: Human
Expression System: HEK293
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi)
TMPK-00389
Species: Human
Expression System: HEK293
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
TMPK-00384
Species: Human
Expression System: HEK293
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi)
TMPK-00388
Species: Human
Expression System: HEK293
FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His)
TMPK-00686
Species: Mouse
Expression System: HEK293
BMP-4 Protein, Human, Recombinant (His)
TMPH-01017
Species: Human
Expression System: E. coli
FGF-18 Protein, Mouse, Recombinant (His)
TMPY-01415
Species: Mouse
Expression System: HEK293
BMP-4 Protein, Bovine, Recombinant (GST)
TMPH-00228
Species: Bovine
Expression System: E. coli
SMAD3 Protein, Human, Recombinant (His)
TMPH-01700
Species: Human
Expression System: Baculovirus
BMP-2 Protein, Human, Recombinant (His)
TMPH-01014
Species: Human
Expression System: E. coli
SOST Protein, Mouse, Recombinant (His)
TMPJ-01294
Species: Mouse
Expression System: Human Cells
FGFR2 Protein, Mouse, Recombinant (His)
TMPY-03389
Species: Mouse
Expression System: HEK293
FGFR2 Protein, Human, Recombinant (aa 1-377, His)
TMPY-01228
Species: Human
Expression System: HEK293
CBFB Protein, Human, Recombinant (His)
TMPY-03504
Species: Human
Expression System: E. coli
FGFR2 Protein, Human, Recombinant (aa 400-821, His & GST)
TMPY-04390
Species: Human
Expression System: Baculovirus-Insect Cells
FGFR2 Protein, Human, Recombinant (alpha(IIIb), His & Avi), Biotinylated
TMPY-06321
Species: Human
Expression System: HEK293
FGFR2 Protein, Human, Recombinant (aa 1-378, His)
TMPY-04273
Species: Human
Expression System: HEK293
FGFR2 Protein, Human, Recombinant (beta IIIc, His)
TMPY-00351
Species: Human
Expression System: HEK293
Fetuin A Protein, Mouse, Recombinant (His)
TMPY-00802
Species: Mouse
Expression System: HEK293
Fetuin A Protein, Human, Recombinant (His)
TMPY-00801
Species: Human
Expression System: HEK293
Leptin Protein, Mouse, Recombinant (mFc)
TMPY-06375
Species: Mouse
Expression System: HEK293
カタログ番号 製品名
L7900 Osteogenesis Compound Library

317 compounds
A unique collection of 317 osteogenesis related compounds for high throughput and high content screening;
L2140 Cancer Cell Differentiation Compound Library

406 compounds
A unique collection of 406 cancer cell differentiation inducing compounds for high throughput and high content screening;