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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T7469 | Alendronic Acid | alendronate | Others |
Alendronic Acid (alendronate) is a nonhormonal medication used for osteoporosis, osteogenesis imperfecta, and several other bone diseases. | |||
T40498L | Dentonin acetate | Dentonin acetate (400090-20-2 Free base) | Others |
Dentonin acetate enhances osteogenesis and facilitates immature adherent cell survival. Dentonin acetate, a synthetic fragment derived from MEPE, can be used in phosphate homeostasis and bone metabolism studies. | |||
T37603L | Osteogenic Growth Peptide (10-14) acetate | Osteogenic Growth Peptide (10-14) acetate(105250-85-9 Free base) | Src |
Osteogenic Growth Peptide (10-14) acetate (Osteogenic Growth Peptide) is a Src inhibitor and an effective mitogen and stimulator of osteogenesis and hematopoiesis. Osteogenic Growth Peptide (10-14) acetate is responsible... | |||
T13794 | Neridronate | Others | |
Neridronate is an aminobisphosphonate,for the treatment of osteogenesis imperfecta (OI) and Paget’s disease of bone (PDB). | |||
T40498 | Dentonin | AC-100 | |
Dentonin (AC-100) is a synthetic fragment derived from MEPE that enhances osteogenesis by promoting osteoprogenitor adhesion and facilitating the survival of immature adherent cells. It does not have a significant effect... | |||
T81173 | Setrusumab | BPS 804 | |
Setrusumab (BPS 804) is a fully humanized monoclonal antibody targeting sclerostin, effectively enhancing bone strength. It is utilized in research on Osteogenesis Imperfecta (OI) and cancer [1]. | |||
T83848 | VnP-16 TFA | ||
VnP-16, a synthetic peptide fragment mirroring amino acids 270-281 of vitronectin (a multifunctional glycoprotein involved in cell attachment, migration, and spreading), promotes attachment and spreading of isolated huma... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TN2081 | Maohuoside A | MAPK | |
Maohuoside A promotes osteogenesis of rat mesenchymal stem cells via BMP and MAPK signaling pathways. | |||
T6S1966 | Curculigoside | Curculigoside A | Antioxidant , NF-κB , JAK , STAT |
1. Curculigoside (Curculigoside A) can prevent bone loss , improve osteogenesis and inhibit osteoclastogenesis of hAFSCs, suggesting its potential use to regulate hAFSC osteogenic differentiation for treating bone disord... | |||
TN5447 | Apigenin 7-O-methylglucuronide | Apigenin-7-O-β-D-glucuronide methyl ester | |
Apigenin 7-O-methylglucuronide did not affect GAG level or secretion, may potentially be used in osteogenesis imperfecta (OI) type I pharmacotherapy in patients with normal GAG content. Apigenin 7-O-methylglucuronide whi... | |||
TN1778 | Isoformononetin | IL Receptor , Antifection | |
Isoformononetin shows fungitoxic activity against Cladosporium sphaerospermum; it also has immunomodulatory activity, it inhibits the differentiation of Th17 cells and B-cell lymphopoesis to promote osteogenesis in estro... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-02626 | FGF-18 Protein, Human, Recombinant (His) | Human | HEK293 |
Fibroblast growth factor 18 (FGF18) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes... | |||
TMPY-00423 | FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc) | Human | HEK293 |
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro... | |||
TMPY-03357 | FGFR2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro... | |||
TMPY-00972 | FGFR2 Protein, Human, Recombinant (His & hFc) | Human | HEK293 |
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro... | |||
TMPY-00875 | Leptin Protein, Human, Recombinant | Human | E. coli |
Leptin is one of the most important hormones secreted by adipocytes, as an adipokine that modulates multiple functions including energy homeostasis, thermoregulation, bone metabolism, endocrine, and pro-inflammatory immu... | |||
TMPH-01016 | GDF-10 Protein, Human, Recombinant (His) | Human | E. coli |
Growth factor involved in osteogenesis and adipogenesis. Plays an inhibitory role in the process of osteoblast differentiation via SMAD2/3 pathway. Plays an inhibitory role in the process of adipogenesis. | |||
TMPY-01930 | Fetuin B Protein, Human, Recombinant (His) | Human | HEK293 |
Fetuin-B, also known as Fetuin-like protein IRL685 and FETUB, is a secreted protein which belongs to thefetuin family. Fetuin-B / FETUB contains twocystatin domains. Fetuin-B is a member of the fetuin family, part of ... | |||
TMPY-01780 | Fetuin B Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Fetuin-B, also known as Fetuin-like protein IRL685 and FETUB, is a secreted protein which belongs to thefetuin family. Fetuin-B / FETUB contains twocystatin domains. Fetuin-B is a member of the fetuin family, part of ... | |||
TMPY-01380 | Cyclophilin B Protein, Human, Recombinant (His) | Human | HEK293 |
PPIB is identified as a candidate gene for OI-IX. Osteogenesis imperfecta (OI) is an inherited disorder of connective tissue typically caused by defects in either COL1A1 or COL1A2. A number of other genes causative of th... | |||
TMPH-02471 | 14-3-3 beta/alpha Protein, Mouse, Recombinant (E. coli, His) | Mouse | E. coli |
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine moti... | |||
TMPH-02472 | 14-3-3 beta/alpha Protein, Mouse, Recombinant (His) | Mouse | Yeast |
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine moti... | |||
TMPK-00386 | FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region con... | |||
TMPK-00390 | FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region con... | |||
TMPK-00387 | FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region con... | |||
TMPK-00385 | FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region con... | |||
TMPK-00389 | FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region con... | |||
TMPK-00384 | FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region con... | |||
TMPK-00388 | FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region con... | |||
TMPK-00686 | FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region con... | |||
TMPH-01017 | BMP-4 Protein, Human, Recombinant (His) | Human | E. coli |
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. Acts in concert with PTHLH/PTHRP to stimu... | |||
TMPY-01415 | FGF-18 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Fibroblast growth factor 18 (FGF18) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes... | |||
TMPH-00228 | BMP-4 Protein, Bovine, Recombinant (GST) | Bovine | E. coli |
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. Acts in concert with PTHLH/PTHRP to stimu... | |||
TMPH-01700 | SMAD3 Protein, Human, Recombinant (His) | Human | Baculovirus |
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in t... | |||
TMPH-01014 | BMP-2 Protein, Human, Recombinant (His) | Human | E. coli |
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including cardiogenesis, neurogenesis, and osteogenesis. Induces cartilage and bone formation. Initiates the canonical... | |||
TMPJ-01294 | SOST Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Sclerostin (SOST) is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. Cerberus/DAN family members are putative BMP antagonists, and include Dan, Cerberus, Gre... | |||
TMPY-03389 | FGFR2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro... | |||
TMPY-01228 | FGFR2 Protein, Human, Recombinant (aa 1-377, His) | Human | HEK293 |
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro... | |||
TMPY-03504 | CBFB Protein, Human, Recombinant (His) | Human | E. coli |
CBFB is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and os... | |||
TMPY-04390 | FGFR2 Protein, Human, Recombinant (aa 400-821, His & GST) | Human | Baculovirus-Insect Cells |
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro... | |||
TMPY-06321 | FGFR2 Protein, Human, Recombinant (alpha(IIIb), His & Avi), Biotinylated | Human | HEK293 |
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro... | |||
TMPY-04273 | FGFR2 Protein, Human, Recombinant (aa 1-378, His) | Human | HEK293 |
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro... | |||
TMPY-00351 | FGFR2 Protein, Human, Recombinant (beta IIIc, His) | Human | HEK293 |
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro... | |||
TMPY-00802 | Fetuin A Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Fetuin-A, also known as Alpha-2-HS-Glycoprotein (AHSG), belongs to the Fetuin family, is a plasma binding protein, and is more abundant in fetal than adult blood. It is involved in several functions, such as endocytosis,... | |||
TMPY-00801 | Fetuin A Protein, Human, Recombinant (His) | Human | HEK293 |
Fetuin-A, also known as Alpha-2-HS-Glycoprotein (AHSG), belongs to the Fetuin family, is a plasma binding protein, and is more abundant in fetal than adult blood. It is involved in several functions, such as endocytosis,... | |||
TMPY-06375 | Leptin Protein, Mouse, Recombinant (mFc) | Mouse | HEK293 |
Leptin is one of the most important hormones secreted by adipocytes, as an adipokine that modulates multiple functions including energy homeostasis, thermoregulation, bone metabolism, endocrine, and pro-inflammatory immu... |
カタログ番号 | 製品名 | ||
---|---|---|---|
L7900 | Osteogenesis Compound Library | 317 compounds | |
A unique collection of 317 osteogenesis related compounds for high throughput and high content screening; | |||
L2140 | Cancer Cell Differentiation Compound Library | 406 compounds | |
A unique collection of 406 cancer cell differentiation inducing compounds for high throughput and high content screening; |