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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T7740 | Protease-Activated Receptor-4 diTFA | Protease-Activated Receptor-4 diTFA(245443-52-1(free base)) | Protease-activated Receptor |
Protease-Activated Receptor-4 diTFA,2454 is the proteinase-activated receptor-4 (PAR4)agonist | |||
T38836L | Protease-Activated Receptor-1, PAR-1 Agonist acetate | Protease-activated Receptor | |
Protease-Activated Receptor-1, PAR-1 Agonist acetate is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist acetate corresponds to PAR1 tethered ligand and whi... | |||
T7513 | Protease-Activated Receptor-2, amide | SLIGKV-NH2 | Protease-activated Receptor |
Protease-Activated Receptor-2, amide (SLIGKV-NH2) is an agonist of PAR2 (IC50 : 10.4 M) | |||
T38836 | Protease-Activated Receptor-1, PAR-1 Agonist | ||
Protease-Activated Receptor-1 (PAR-1) Agonist, a selective peptide, activates the PAR-1 receptor by mimicking the specific actions of thrombin. It corresponds to the PAR1 tethered ligand, facilitating selective activatio... | |||
T36288 | Protease-Activated Receptor-1, PAR-1 Agonist TFA | ||
Protease-Activated Receptor-1 (PAR-1) Agonist TFA is a selective peptide that acts as an agonist for the proteinase-activated receptor-1 (PAR-1). Corresponding to the tethered ligand of PAR-1, this compound mimics the ac... | |||
T7380 | Protease-Activated Receptor-4 | Protease-activated Receptor | |
Protease-Activated Receptor-4 is the proteinase-activated receptor-4 (PAR4) agonist, with Antiplatelet Therapy | |||
T36289 | Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA | ||
Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA is a peptide that acts as an agonist for the proteinase-activated receptor (PAR-3)[1]. | |||
TP1046 | SLIGRL-NH2 | Protease-Activated Receptor-2 Activating Peptide | Protease-activated Receptor |
SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is a protease-activated receptor-2 (PAR-2) agonist that induces non-histaminergic pruritus. | |||
T36286 | Protease-Activated Receptor-3 (PAR-3) (1-6), human | ||
TFRGAP-amide, human PAR-3-derived tethered ligand sequence which does not activate PAR-3 but rather activates PAR-1 and PAR-2, either in Jurkat or in other PAR-expressing cells. | |||
T1986L | Atopaxar Hydrobromide | Protease-activated Receptor | |
Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome. | |||
T1893 | Parmodulin 2 | ML 161 | Protease-activated Receptor |
Parmodulin 2 (ML 161) is the inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50: 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). It also inhibits thromb... | |||
TQ0012 | AZ3451 | Protease-activated Receptor | |
AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM). | |||
T7137 | I-191 | Protease-activated Receptor | |
I-191 is a potent antagonist of protease-activated receptor 2 (PAR2), inhibits multiple signaling functions in human cancer cells. | |||
T1986 | Atopaxar | E5555,ER-172594-00 | Protease-activated Receptor |
Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome. | |||
T64285 | Protease-Activated Receptor-1 antagonist 2 | ||
Protease-Activated Receptor-1 antagonist 2 is a selective, orally active protease-activated receptor-1 (PAR-1) antagonist (IC50: 7 nM). It has shown good pharmacokinetic properties and can be used for studies related to ... | |||
T62507 | Protease-Activated Receptor-1 antagonist 1 | ||
Protease-Activated Receptor-1 antagonist 1 (Compound 13) is a protease-activated receptor 1 (PAR-1) antagonist with an IC50 of 3 nM obtained by the FLIPR technique. antagonist 1 can be used to study thrombotic cardiovasc... | |||
T63382 | Protease-Activated Receptor-1 antagonist 3 | ||
Protease-Activated Receptor-1 antagonist 3 is a potent antagonist (IC50: 7 nM) of Protease-Activated Receptor 1protease-activated receptor-1. antagonist 3 exhibits binding affinity to hERG K+ channels (IC50: 9 μM). | |||
T74266 | Protease-Activated Receptor-1 antagonist 2 | ||
Protease-Activated Receptor-1 Antagonist 2 is an orally active antagonist of protease-activated receptor-1 (PAR-1), demonstrating significant potency with an IC 50 of 7 nM. It exhibits favorable pharmacokinetic character... | |||
TP1046L | PAR-2 Activating Peptide acetate | SLIGRL-NH2 acetate,PAR-2 Activating Peptide acetate(171436-38-7 free base),Protease-Activated Receptor-2 Activating Peptide acetate | Protease-activated Receptor |
PAR-2 Activating Peptide acetate (SLIGRL-NH2 acetate) is an agonist of Protease-Activated Receptor-2 (PAR-2). | |||
T2370 | AC-55541 | AOB2796 | Proteasome , Protease-activated Receptor |
AC-55541 (AOB2796) is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM. | |||
T7013 | Vorapaxar | SCH 530348,MK-5348 | Protease-activated Receptor |
Vorapaxar (MK-5348) (SCH 530348) is an effective and orally active thrombin receptor (PAR-1) antagonist (Ki: 8.1 nM). | |||
T75902 | SLIGRL-NH2 TFA | Protease-Activated Receptor-2 Activating Peptide TFA | |
SLIGRL-NH2 TFA, also known as Protease-Activated Receptor-2 Activating Peptide TFA, is a Protease-Activated Receptor-2 (PAR-2) agonist [1]. | |||
T12870 | SCH79797 dihydrochloride | Apoptosis , Others , Protease-activated Receptor | |
SCH79797 dihydrochloride is a selective antagonist of nonpeptide protease activated receptor 1 (PAR1). | |||
T8917 | PAR-2-IN-1 | IUN76750 | Protease-activated Receptor |
PAR-2-IN-1 (IUN76750) is a PAR- 2 signaling pathway inhibitor with anti-inflammatory and anticancer effects. | |||
T3098 | Vorapaxar sulfate | SCH 530348 sulfate,Zontivity,vorapaxar monosulfate | Protease-activated Receptor |
Vorapaxar sulfate (Zontivity) is a potent and orally active thrombin receptor (PAR-1) antagonist. | |||
T7625 | TRAP-6 | PAR-1 agonist peptide,Thrombin Receptor Activator Peptide 6,TRAP-6(2TFA) | Protease-activated Receptor |
TRAP-6 (Thrombin Receptor Activator Peptide 6)(2TFA) is an agonist of protease-activated receptor 1 (PAR1). | |||
TP1065 | PAR-4 Agonist Peptide, amide TFA | PAR-4-AP (TFA),AY-NH2 (TFA) | Protease-activated Receptor |
PAR-4 Agonist Peptide, amide TFA (PAR-4-AP (TFA)), is a selective activator of the proteinase-activated receptor-4 (PAR-4), demonstrating specificity by not influencing PAR-1 or PAR-2, and its activity can be inhibited b... | |||
T4186 | AC-264613 | AC264613 | Protease-activated Receptor |
AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2). AC-264613(AC264613) suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macropha... | |||
T7623 | PAR-4 Agonist Peptide, amide | AY-NH2,PAR-4 Agonist Peptide, amide(2TFA),PAR-4-AP | Protease-activated Receptor |
PAR-4 Agonist Peptide, amide (AY-NH2) is an agonist of proteinase-activated receptor-4 (PAR-4). | |||
T7573 | TFLLR-NH2 | TFLLR-NH2(2TFA) | Protease-activated Receptor |
TFLLR-NH2(2TFA) is an agonist of PAR1 (EC50 :1.9 μM). | |||
T7496 | Thrombin Receptor Activator for Peptide 5 (TRAP-5) | Thrombin Receptor Activator for Peptide | Protease-activated Receptor |
Thrombin Receptor Activator for Peptide 5 (TRAP-5), also known as Coagulation Factor II Receptor (1-5) or Proteinase Activated Receptor 1 (1-5), is employed in coronary heart disease (CHD) research. | |||
TP1378 | 2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base) | 2-Furoyl-LIGRLO-amide | Protease-activated Receptor |
2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base) is a potent and selective protease-activated receptor 2 (PAR2) agonist. | |||
T63966 | BMS-986141 | UDM-003183 | Protease-activated Receptor |
BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614 exhibits significant antithrombotic effects. | |||
T21699L | VKGILS-NH2 Acetate | VKGILS-NH2 Acetate (942413-05-0 Free base) | Protease-activated Receptor |
VKGILS-NH2 Acetate is a reversed amino acid sequence control peptide for SLIGKV-NH2, a protease-activated receptor 2 (PAR2) agonist. | |||
TP1904L | FSLLRY-NH2 TFA(245329-02-6 free base) | Protease-activated Receptor | |
FSLLRY-NH2 TFA is a is a protease-activated receptor 2 (PAR2) inhibitor. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in iso... | |||
T22792 | FR-171113 | Others | |
Protease-activated receptor 1 antagonist | |||
T23282 | RWJ-56110 | Others | |
protease-activated receptor-1 (PAR1) antagonist | |||
T27406 | GB83 | GB-83,GB 83 | |
GB83 is a selective human protease activated receptor 2 (PAR2) antagonist. | |||
T68583 | Nco 700 | ||
Nco 700 is a synthetic inhibitor of calcium-activated protease. | |||
T75871 | FSLLRY-NH2 TFA | ||
FSLLRY-NH2 TFA is a protease-activated receptor 2 (PAR2) inhibitor [1] . | |||
TP1628 | Activated Protein C (390-404), human | ||
Activated Protein C (390-404), human, a peptide derived from the vitamin K-dependent serine protease, effectively suppresses the anticoagulant activity of APC[1]. | |||
T17200 | UDM-001651 | Others | |
UDM-001651 is an effective and orally bioavailable protease-activated receptor 4 antagonists (IC50=4 nM; Kd=1.4 nM). UDM-001651 displays antiplatelet potency (IC50=25 nM) in a γ-thrombin-induced platelet-rich plasma aggr... | |||
T11369 | GB-110 | Others | |
GB-110 selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM. GB-110 is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist. | |||
T80111 | TRAP-5 amide | ||
TRAP-5 amide is a peptide agonist for protease-activated receptor 1 (PAR 1) [1]. | |||
T73854 | GB-110 hydrochloride | ||
GB-110 hydrochloride, a potent and orally active nonpeptidic agonist of the protease-activated receptor 2 (PAR2), selectively triggers PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM [1]. | |||
T22933 | LRGILS-NH2 | Others | |
LRGILS-NH2 is a reversed amino acid sequence control peptide for SLIGRL-NH2, a protease-activated receptor-2 (PAR2) agonist that facilitates gastrointestinal transit in vivo. | |||
T14684 | BMS-986120 | Others | |
T11369L | GB-110 hydrochloride (1252806-70-4 free base) | GB-110 hydrochloride | Others |
GB-110 hydrochloride selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM. GB-110 hydrochloride is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR... | |||
TP2234 | Coagulation factor II (thrombin) B chain fragment [Homo sapiens] | Others | |
Thrombin is a "trypsin-like" serine protease that is encoded by the F2 gene in humans. Thrombin is produced by the enzymatic cleavage of two sites on prothrombin by activated Factor X (Xa). Thrombin in turn acts as a ser... | |||
T75903 | VKGILS-NH2 TFA | ||
VKGILS-NH2 TFA is a reversed-sequence control peptide for SLIGKV-NH2, a protease-activated receptor 2 (PAR2) agonist. It demonstrates no impact on cellular DNA synthesis [1] [2]. |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T0800 | Danthron | Dantron,1,8-Dihydroxyanthraquinone,Chrysazin,Antrapurol | Virus Protease , Antibacterial , AMPK , Autophagy |
Danthron (Antrapurol) is a natural product, regulates glucose, and lipid metabolism by activating AMPK. | |||
TMA1012 | Ganoderiol F | Androgen Receptor , HIV Protease , Autophagy | |
Ganoderiol F has anti-inflammatory, cytotoxic and anti-HIV activity, it inhibits activity of topoisomerases in vitro, and it inhibits human immunodeficiency virus-1 protease with IC(50) values of 20-40 microM. It induced... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPH-00134 | AcMNPV Viral cathepsin Protein (His & SUMO) | AcMNPV | E. coli |
Cysteine protease that plays an essential role in host liquefaction to facilitate horizontal transmission of the virus. Accumulates within infected cells as an inactive proenzyme (proV-CATH), which is activated by proteo... | |||
TMPY-03653 | CTRL Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CTRL-1, also known as chymotrypsin-like protease, belongs to thepeptidase S1 family. CTRL-1 contains 1peptidase S1 domain. Its expression is increased in preeclampsia (PE). Placental-derived chymotrypsin-like protease is... | |||
TMPJ-00542 | TPSB2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites faci... | |||
TMPH-02237 | TMPRSS2 Protein, Human, Recombinant (His & Myc) | Human | HEK293 Cells |
Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-... | |||
TMPJ-01116 | HABP2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Hyaluronan-binding protein 2(HABP2) is an extracellular serine protease which binds hyaluronic acid. It secreted as an inactive single-chain precursor and is then activated to a heterodimeric form, which consists of a 50... | |||
TMPH-02236 | TMPRSS2 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-... | |||
TMPH-02832 | Serpin A5 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
Heparin-dependent serine protease inhibitor acting in body fluids and secretions. Inactivates serine proteases by binding irreversibly to their serine activation site. Involved in the regulation of intravascular and extr... | |||
TMPJ-00845 | CTSE Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Cathepsin E (CTSE) is a gastric aspartyl protease that functions as a disulfide-linked homodimer. It is a member of the Peptidase C1 family, and has a specificity similar to that of Pepsin A and Cathepsin D. CTSE is loca... | |||
TMPY-02014 | Coagulation factor VII/F7 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Coagulation factor VII, also known as Serum prothrombin conversion accelerator, Factor VII, F7 and FVII, is a member of the peptidase S1 family. Factor VII is one of the central proteins in the coagulation cascade. It is... | |||
TMPY-02831 | Caspase-7 Protein, Human, Recombinant (His) | Human | E. coli |
Caspase 7, also known as caspase-7 and MCH3, belongs to the cysteine-aspartic acid protease (caspase) family. Caspases play a role in the signal transduction pathways of apoptosis, necrosis and inflammation. There are tw... | |||
TMPJ-00490 | Serpin A5 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent i... | |||
TMPY-01711 | Serpin B2 Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, infl... | |||
TMPY-00818 | Granzyme H/GZMH Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Granzymes are key components of the immune response that play important roles in eliminating host cells infected by intracellular pathogens. Several granzymes are potent inducers of cell death. A total of eight granzymes... | |||
TMPJ-00837 | LAMP1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Lysosomal associated membrane protein 1 (LAMP1) is an approximately 120 kDa transmembrane glycoprotein that is a major protein component of lysosomal membranes. Mature mouse LAMP1 consists of a 346 amino acid (aa) intral... | |||
TMPH-01664 | OMA1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Activated in response to various mitochondrial stress, leading to the proteolytic cleavage of target proteins, such as OPA... |