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T16566 |
Propyl pyrazole triol
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PPT |
Estrogen Receptor/ERR
,
Estrogen/progestogen Receptor
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Propyl pyrazole triol (PPT) is a selective agonist of estrogen receptor alpha. The relative binding affinity of Propyl pyrazole triol for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: ... |
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T21981 |
Phthalazinone pyrazole
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Aurora Kinase
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Phthalazinone pyrazole is potent, selective, and orally bioavailable inhibitor of Aurora-A kinase. Aurora-A is overexpressed in a variety of tumor types and displays oncogenic activity. |
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T7842 |
1H-Pyrazole-3-carboxylic acid
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Others
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1H-Pyrazole-3-carboxylic acid is an important intermediate in the synthesis of various pharmaceuticals and agricultural chemicals and is also used in the synthesis of compounds such as pyrazolones, pyrazole amides, and p... |
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T9324 |
1,5-diphenylpyrazole-3-carboxylic acid
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1H-PYRAZOLE-3-CARBOXYLIC ACID, 1,5-DIPHENYL- |
Others
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1,5-diphenylpyrazole-3-carboxylic acid (1H-PYRAZOLE-3-CARBOXYLIC ACID, 1,5-DIPHENYL-) is a plant-physiologically tolerable salt radical or any desired ester radical. |
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T2602 |
Barasertib-HQPA
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1H-Pyrazole-3-acetamide,Barasertib,AZD1152-HQPA,AZD2811,AZD1152-HQPA|AZD2811 |
Apoptosis
,
Aurora Kinase
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Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A. |
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T21897 |
Methylpiperidino pyrazole
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Estrogen/progestogen Receptor
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Methylpiperidino pyrazole is an ERα inhibitor and can prevent the BPS-induced Rb phosphorylation and cell cycle progression. |
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T9281 |
(S)-2-((R)-3-(4-chlorophenyl)-N’-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboximidamido)-3-methylbutanamide
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Others
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(S)-2-((R)-3-(4-chlorophenyl)-N’-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboximidamido)-3-methylbutanamide is a cannabinoid receptor antagonist/inverse agonist. |
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T29302 |
1H-Pyrazole, 4,5-dihydro-1,3,5-triphenyl-
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1H-Pyrazole, 4,5-dihydro-1,3,5-triphenyl- is a bioactive chemical. |
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T50071 |
Xanthine dehydrogenase Inhibitor 1
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Others
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5-amino-1-[4-(trifluoromethyl)phenyl]-1H-pyrazole-4-carbonitrile is a compound used as a molecular structural unit and is considered to be an inhibitor of enzymes such as COX-2, 5-LOX, etc., and possesses a wide range of... |
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T50107 |
Neuroprotective agent 1
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Others
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ethyl 2-[3,5-bis(trifluoromethyl)phenyl]-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate is a synthetic compound belonging to the curcumin family. It is involved in the regulation of immune response and inflammation through ... |
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T50023 |
PDE4-IN-20
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Others
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ethyl 1-(4-aminophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate, also known as EAPT, is a potent and selective PDE4 inhibitor that regulates intracellular cyclic adenosine monophosphate (cAMP) levels. It has been u... |
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T14557 |
BI-1935
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Epoxide Hydrolase
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BI-1935 is an inhibitor of soluble epoxide hydrolase (sEH). For diseases related to cardiovascular disease. |
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T8703 |
YGsy2p-IN-1
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Others
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yGsy2p-IN-1 is a potent yeast glycogen synthase 2 (yGsy2p) and human glycogen synthase 1 (hGYS1) inhibitor. yGsy2p-IN-H23 a pyrazole inhibitor,and is used for glycogen storage diseases (GSDs) |
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T16686 |
Pyr10
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TRP/TRPV Channel
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Pyr10 is a pyrazole derivative and a selective TRP cation 3 inhibitor. Pyr10 has the ability to distinguish between receptor-operated TRPC3 and native stromal interaction molecule 1 (STIM1)/Orai1 channels. Pyr10 inhibits... |
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T61619 |
XN methyl pyrazole
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XN methyl pyrazole exhibits beneficial effects on diet-induced obesity and enhances energy expenditure in mice fed with a high-fat diet [1]. |
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T67474 |
3-(p-Tolyl)-1H-pyrazole
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3-(p-Tolyl)-1H-pyrazole is a useful organic compound for research related to life sciences. The catalog number is T67474 and the CAS number is 59843-75-3. |
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T66472 |
1H-Pyrazole-3,5-dicarboxylic acid
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1H-Pyrazole-3,5-dicarboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66472 and the CAS number is 3112-31-0. |
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T67682 |
4-Methyl-1H-pyrazole hydrochloride
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4-Methyl-1H-pyrazole hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T67682. |
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T67134 |
1H-Pyrazole-1-carboximidamide hydrochloride
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1H-Pyrazole-1-carboximidamide hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T67134 and the CAS number is 4023-02-3. |
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T67598 |
3-Methyl-5-phenyl-1H-pyrazole
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3-Methyl-5-phenyl-1H-pyrazole is a useful organic compound for research related to life sciences. The catalog number is T67598 and the CAS number is 3347-62-4. |
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T67506 |
3-Amino-1H-pyrazole-4-carboxamide
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3-Amino-1H-pyrazole-4-carboxamide is a useful organic compound for research related to life sciences. The catalog number is T67506 and the CAS number is 5334-31-6. |
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T66363 |
3-Amino-1H-pyrazole-4-carbonitrile
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3-Amino-1H-pyrazole-4-carbonitrile is a useful organic compound for research related to life sciences. The catalog number is T66363 and the CAS number is 16617-46-2. |
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T67140 |
1-methyl-1H-pyrazole-4-carboxylic acid
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1-methyl-1H-pyrazole-4-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T67140 and the CAS number is 113100-53-1. |
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T60162 |
1H-Pyrazole-5-carboxamide, 4-(5-chloro-2-furanyl)-1,3-bis(2,4-difluorophenyl)-4,5-dihydro-5-methyl-N-[(4-methyl-2-morpholinyl)methyl]
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Others
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1H-Pyrazole-5-carboxamide, 4-(5-chloro-2-furanyl)-1,3-bis(2,4-difluorophenyl)-4,5-dihydro-5-methyl-N-[(4-methyl-2-morpholinyl)methyl] is an antifibrotic agent. |
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T65741 |
1-Methyl-3-propyl-1H-pyrazole-5-carboxylic acid
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1-Methyl-3-propyl-1H-pyrazole-5-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T65741 and the CAS number is 139755-99-0. |
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T66374 |
Tert-Butyl 4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate
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tert-Butyl 4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T66374 and the CAS number is 1280210-79-8. |
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T65742 |
1-Methyl-4-nitro-3-propyl-(1H)-pyrazole-5-carboxamide
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1-Methyl-4-nitro-3-propyl-(1H)-pyrazole-5-carboxamide is a useful organic compound for research related to life sciences. The catalog number is T65742 and the CAS number is 139756-01-7. |
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T64521 |
4-Amino-1-methyl-3-(2-methylpropyl)-1H-pyrazole-5-carboxamide
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4-Amino-1-methyl-3-(2-methylpropyl)-1H-pyrazole-5-carboxamide is a useful organic compound for research related to life sciences. The catalog number is T64521 and the CAS number is 268204-00-8. |
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T67141 |
1-Methyl-4-nitro-3-propyl-1H-pyrazole-5-carboxylic acid
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1-Methyl-4-nitro-3-propyl-1H-pyrazole-5-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T67141 and the CAS number is 139756-00-6. |
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T67079 |
4-Amino-1-methyl-3-N-propyl-1H-pyrazole-5-carboxamide
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4-Amino-1-methyl-3-N-propyl-1H-pyrazole-5-carboxamide is a useful organic compound for research related to life sciences. The catalog number is T67079 and the CAS number is 139756-02-8. |
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T65014 |
3-Amino-4-pyrazolecarboxamide hemisulfate
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3-Amino-4-pyrazolecarboxamide hemisulfate is a useful organic compound for research related to life sciences. The catalog number is T65014 and the CAS number is 27511-79-1. |
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T35548 |
Dynapyrazole A
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Dynamin
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Dynapyrazole A is a specific inhibitor of microtubule dynamin with IC50s of 2.3 and 2.6 μM for dynein 1 and dynein 2-dependent microtubule gliding. Dynapyrazole A inhibits Hedgehog signaling with an IC50 of 1.9 μM. |
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T66268 |
Ethyl 5-Propylpyrazole-3-carboxylate
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Ethyl 5-Propylpyrazole-3-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T66268 and the CAS number is 92945-27-2. |
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T35316 |
Zometapine
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CI 716,Zolazepamum,CI-716,CI716,Flupyrazapon |
Others
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Zometapine (CI 716) is an antidepressant compound that is a derivative of pyrazole and diazepine. |
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T0569 |
Pyrazinoic acid
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Pyrazinecarboxylic acid |
Others
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Pyrazinoic acid (Pyrazinecarboxylic acid) is the intermediate of pyrazole thiamethoxam sulfur. |
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T0980 |
Nifenazone
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Niapyrin,Nicodone,Nicazane |
COX
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Nifenazone (Nicodone) is a pyrazole drug, used in the in the treatment of rheumatic disorders. |
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T11829 |
LDH-IN-1
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Dehydrogenase
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LDH-IN-1 is a pyrazole-based human lactate dehydrogenase (LDH) inhibitor(IC50s of 32 and 27 nM for LDHA and LDHB, respectively). |
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T3295 |
1-Methyl-1H-pyrazol-3-amine
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Others
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1-Methyl-1H-pyrazol-3-amine is a pyrazole compound. It has been used in the synthesis of various compounds such as drugs, dyes and polymers. It is also an important intermediate in the synthesis of certain drugs. It has ... |
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T4425 |
JK-P3
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VEGFR
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JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube format... |
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T39646 |
Atinvicitinib
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Atinvicitinib, a pyrazole compound, exhibits promise for investigating atopic dermatitis. |
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T14836 |
Bucloxic acid
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804CB,Bucloxonic acid,Esfar |
Others
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Bucloxic acid is an anti-inflammatory pyrazole derivative used in the treatment of chronic glomerular nephropathies. |
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T33918 |
Pentanochlor
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Hortox,Niagara 4512,Solane,Dutom,FMC 4512 |
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Pentanochlor can be used in agricultural use and biological study of herbicide composition containing a pyrazolyl pyrazole derivative. The impairment of mobility and development in freshwater snails (Physa fontinalis and... |
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T33534 |
Muzolimine
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Edrul,Muzolimina,Muzoliminum |
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Muzolimine is pyrazole diuretic with long duration and high capacity of action. It was proposed for kidney failure and hypertension but was withdrawn worldwide because of severe neurological effects. |
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T35313 |
Zolazepam
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CI716,CI 716,CI-716,Flupyrazapon |
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Zolazepam(CI 716) is a derivative of pyrazole and diazazone that is structurally related to benzodiazepines and is used in veterinary medicine as an anesthetic for a variety of animals. |
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T71058 |
Doramapimod HCl
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Doramapimod HCl is the salt form of Doramapimod, a member of the N-pyrazole-N'-naphthly urea class of p38MAPK inhibitors, which binds to the kinase with both slow association and dissociation rates. BIRB -796 has entere... |
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T68117 |
Nortopixantrone
|
BBR 3438 |
Others
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Nortopixantrone（BBR 3438） is a novel 9-azacyclophenanthracene pyrazole that shows antitumor activity in a human prostate cancer model. |
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T23832 |
Bucloxic acid calcium salt
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Bucloxic acid calcium,CB 804 calcium,Calcium esfar |
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Bucloxic acid calcium salt is a pyrazole derivative, the calcium salt of Bucloxic acid. It is an anti-inflammatory drug with analgesic and antipyretic properties. It is also used in the study of chronic glomerulonephropa... |
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T63507 |
Feniralstat
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Feniralstat is a pyrazole derivative, a potent inhibitor of kallikrein, which inhibits human plasma kinase (pKal) (IC50: 6.7 nM).Feniralstat does not inhibit human KLK1, human FXIa and human factor Xlla (IC50 >40 μM). |
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T78378 |
PK7088
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Others
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PK7088, a pyrazole-based peptide, selectively reactivates mutant p53 to a conformation with wild-type characteristics, demonstrating anticancer activity in oncological studies [1]. |
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T61674 |
COX-2/5-LOX-IN-1
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COX-2/5-LOX-IN-1 (compound 3a), a benzothiophen-2-yl pyrazole carboxylic acid derivative, is a potent and dual inhibitor of COX-2 / 5-LOX. It exhibits superior analgesic and anti-inflammatory properties compared to Celec... |
