Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Seralutinib (GB002) is an inhibitor of inhaled PDGFRα and PDGFRβ. It is used in the study for pulmonary arterial hypertension.
説明 | Seralutinib (GB002) is an inhibitor of inhaled PDGFRα and PDGFRβ. It is used in the study for pulmonary arterial hypertension. |
In vivo | GB002 dose- and time-dependently induces lung BMPR2 protein expression.GB002-mediated inhibition of lung PDGFRα/β phosphorylation in healthy Sprague Dawley rats immediately post inhalation[1]. |
別名 | GB002 |
分子量 | 469.54 |
分子式 | C27H27N5O3 |
CAS No. | 1619931-27-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (212.98 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Seralutinib 1619931-27-9 Angiogenesis Tyrosine Kinase/Adaptors PDGFR PK 10571 GB-002 inhibit arterial PK10571 GB 002 PK-10571 PAH Pulmonary hypertension Inhibitor GB002 Platelet-derived growth factor receptor inhibitor