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阻害剤

天然化合物

カタログ番号	製品名	別名	ターゲット
T82222	H-D-MeAla-EtVaI-VaI-MeLeu-AIa-D-AIa-MeLeu-MeLeu-MeVaI-MeBmt(OAc)-Abu-O-CH2-CH2-NHMe
	H-D-MeAla-EtVal-Val-MeLeu-Ala-D-Ala-MeLeu-MeLeu-MeVal-MeBmt(OAc)-Abu-O-CH2-CH2-NHMe is a derivative of cyclosporin A lacking immunosuppressive properties with potential application in congenital muscular dystrophy resear...
T9622	MF-766		Prostaglandin Receptor
	MF-766 is a highly potent, selective and orally active EP4 antagonist with a Ki of 0.23 nM. It behaves as a full antagonist with an IC50 of 1.4 nM (shifted to 1.8 nM in the presence of 10% HS) in the functional assay. It...		Prostaglandin Receptor
T2125	Trametinib	GSK1120212,JTP-74057	Apoptosis , MEK , Autophagy
	Trametinib (GSK1120212) is a MEK inhibitor that inhibits MEK1 and MEK2 (IC50=0.7/0.9 nM) with ATP non-competitive and oral activity. Trametinib activates autophagy and induces apoptosis.		Apoptosis , MEK , Autophagy
T5857	Trametinib (DMSO solvate)	Trametinib DMSO solvate,GSK-1120212 (DMSO solvate),Trametinib dimethyl sulfoxide,JTP-74057 (DMSO solvate)	Apoptosis , MEK
	Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is a Highly Potent and Selective MEK Inhibitor that specifically inhibits MEK1/2(IC50 :2 nM)		Apoptosis , MEK
T11506	Guaiapate	Mg 5454,Klamar	Others
	Guaiapate has an antitussive and sedative effect.		Others
T0284	Sulfogaiacol	guaiacolsulfonate	Others , Antibacterial
	Sulfogaiacol (guaiacolsulfonate) is an antitussive agent, used for acute respiratory tract infections and cough.		Others , Antibacterial
T3267	Potassium guaiacolsulfonate hemihydrate	Potassium guaiacolsulfonate,Potassium 4-guaiacolsulfonate hemihydrate	Antibacterial , Antibiotic
	Potassium guaiacolsulfonate hemihydrate (Potassium guaiacolsulfonate) is an aromatic sulfonic acid used in medicine as an expectorant.		Antibacterial , Antibiotic
T40125	4,5-Dichloroguaiacol
	4,5-Dichloroguaiacol is the major component of chlorinated phenol.
T124764	Guaiaretic acid
	Guaiaretic acid is a useful organic compound for research related to life sciences. The catalog number is T124764 and the CAS number is 500-40-3.
T124473	Threo-Guaiacylglycerol-beta-coniferyl aldehyde ether
	threo-Guaiacylglycerol-beta-coniferyl aldehyde ether is a useful organic compound for research related to life sciences and the catalog number is T124473.
T21072	4-Aminoguaiacol
	4-Aminoguaiacol is a bioactive chemical.
T60493	Guaiacol Carbonate
	Guaiacol Carbonate is an expectorant that acts via virtue of a reflex from the stomach by way of the afferent gastric nerves to the medullary centers, then via peripherally again to the respiratory tract[1].
T36594	4-Chloroguaiacol
	4-Chloroguaiaco (4-Chloro-2-methoxyphenol), a derivative of phenol, demonstrates antimicrobial efficacy, inhibiting Staphylococcus aureus and Escherichia coli with minimum inhibitory concentrations (MICs) of 110 μg/mL fo...
T39145	4,6-Dichloroguaiacol
	4,6-Dichloroguaiacol elicits biochemical and morphological alterations in human peripheral blood lymphocytes in vitro.
T125992	Threo-Guaiacylglycerol β-dihydroconiferyl ether
	threo-Guaiacylglycerol β-dihydroconiferyl ether is a useful organic compound for research related to life sciences and the catalog number is T125992.
T124616	Furoguaiaoxidin
	Furoguaiaoxidin is a useful organic compound for research related to life sciences. The catalog number is T124616 and the CAS number is 58096-91-6.
T124284	Erythro-Guaiacylglycerol-beta-coniferyl aldehyde ether
	Erythro-Guaiacylglycerol-beta-coniferyl aldehyde ether is a useful organic compound for research related to life sciences and the catalog number is T124284.
T40299	4,5,6-Trichloroguaiacol
	4,5,6-Trichloroguaiacol is a phenolic compound that is commonly found in the effluents generated by bleached kraft pulp mills.
T40655	3,4,5-Trichloroguaiacol
	3,4,5-Trichloroguaiacol is a phenolic compound that is commonly found in the effluents originating from bleached kraft pulp mills.
T125621	Erythro-Guaiacylglycerol β-coniferyl ether
	erythro-Guaiacylglycerol β-coniferyl ether is a useful organic compound for research related to life sciences and the catalog number is T125621.
T126154	(-)-Dihydroguaiaretic acid
	(-)-Dihydroguaiaretic acid is a useful organic compound for research related to life sciences and the catalog number is T126154.
T32015	Guaiacyl acetate	NSC-3831,NSC 3831,NSC3831
	Guaiacyl acetate is a biochemical.
T40180	Tetrachloroguaiacol
	Tetrachloroguaiacol, the predominant chlorinated phenol, is generated through the chlorine bleaching process of wood pulp.
T126147	Di-O-demethylisoguaiacin
	Di-O-demethylisoguaiacin is a useful organic compound for research related to life sciences. The catalog number is T126147 and the CAS number is 125074-14-8.
T126216	1α,7α,10αH-Guaia-4,11-dien-3-one
	1α,7α,10αH-Guaia-4,11-dien-3-one is a useful organic compound for research related to life sciences and the catalog number is T126216.
T31215	DB-766	DB766
	DB-766 is a potential chemotherapeutic candidate for Chagas' disease treatment. DB-766 exhibits strong trypanocidal activity and excellent selectivity for bloodstream trypomastigotes and intracellular amastigotes (Y stra...

Compounds

H-D-MeAla-EtVaI-VaI-MeLeu-AIa-D-AIa-MeLeu-MeLeu-MeVaI-MeBmt(OAc)-Abu-O-CH2-CH2-NHMe

Target: Prostaglandin Receptor

Trametinib

T2125

Synonym: GSK1120212,JTP-74057

Target: Apoptosis, MEK, Autophagy

Trametinib (DMSO solvate)

T5857

Synonym: Trametinib DMSO solvate,GSK-1120212 (DMSO solvate),Trametinib dimethyl sulfoxide,JTP-74057 (DMSO solvate)

Target: Apoptosis, MEK

Guaiapate

T11506

Synonym: Mg 5454,Klamar

Target: Others

Sulfogaiacol

T0284

Synonym: guaiacolsulfonate

Target: Others, Antibacterial

Potassium guaiacolsulfonate hemihydrate

T3267

Synonym: Potassium guaiacolsulfonate,Potassium 4-guaiacolsulfonate hemihydrate

Target: Antibacterial, Antibiotic

threo-Guaiacylglycerol-beta-coniferyl aldehyde ether

threo-Guaiacylglycerol β-dihydroconiferyl ether

Erythro-Guaiacylglycerol-beta-coniferyl aldehyde ether

T124284

Synonym:

Target:

4,5,6-Trichloroguaiacol

T40299

Synonym:

Target:

3,4,5-Trichloroguaiacol

T40655

Synonym:

Target:

erythro-Guaiacylglycerol β-coniferyl ether

T125621

Synonym:

Target:

(-)-Dihydroguaiaretic acid

Synonym: NSC-3831,NSC 3831,NSC3831

Di-O-demethylisoguaiacin

T126147

Synonym:

Target:

1α,7α,10αH-Guaia-4,11-dien-3-one

カタログ番号	製品名	別名	ターゲット
TN6034	Aristolactam AIa
	Aristolactam AIa is a natural product for research related to life sciences. The catalog number is TN6034 and the CAS number is 97399-90-1.
TJS2190	Nordihydroguaiaretic acid	NDGA,Dihydronorguaiaretic Acid	Antioxidant , Ferroptosis , Lipoxygenase , Autophagy
	Nordihydroguaiaretic acid (NDGA) (NDGA) is a phenolic antioxidant found in the leaves and twigs of the evergreen desert shrub, Larrea tridentata (Sesse and Moc. ex DC) Coville (creosote bush). It is a recognized inhibito...		Antioxidant , Ferroptosis , Lipoxygenase , Autophagy
T3159	Guaiazulene	azulon,Vetivazulen,Eucazulen	Others , Endogenous Metabolite
	Guaiazulene (azulon) belongs to the class of organic compounds known as guaianes.		Others , Endogenous Metabolite
T1301	Guaiacol	O-methylcatechol,2-hydroxyanisole,o-methoxyphenol,2-Methoxyphenol	NF-κB , COX , Endogenous Metabolite
	Guaiacol (2-Methoxyphenol) is a precursor to various flavorants, such as eugenol and vanillin. Its derivatives are used medicinally as an expectorant, antiseptic, and local anesthetic. It also can be used as an indicator...		NF-κB , COX , Endogenous Metabolite
T13716	(+)-Guaiacin		Others
	(+)-Guaiacin is a compound isolated from the bark of Machilus wangchiana Chun. It shows potent in vitro activities against the release of β-glucuronidase in rat polymorphonuclear leukocytes (PMNs) induced by platelet-act...		Others
T5525	Shiraiachrome A
	Shiraiachrome A is a natural product for research related to life sciences. The catalog number is T5525 and the CAS number is 124709-39-3.
TN6585	2-Methoxyfuranoguaia-9-ene-8-one
	2-Methoxyfuranoguaia-9-ene-8-one is a natural product for research related to life sciences. The catalog number is TN6585 and the CAS number is 88010-62-2.
T81701	Nardoguaianone K	10-epi-Nardoguaianone J
	Nardoguaianone K, a guaiane-type sesquiterpenoid isolated from the roots of Nardostachys chinensis, has potential applications in pancreatic cancer research [1] [2].
T82441	Erythro-guaiacylglycerol-β-ferulic acid ether
	Erythro-guaiacylglycerol-β-ferulic acid ether, a natural product, is isolated from Gueldenstaedtia verna [1].
TN4004	Erythro-Guaiacylglycerol β-dihydroconiferyl ether
	Erythro-Guaiacylglycerol β-dihydroconiferyl ether is extracted from Canadian maple syrup with potential antioxidant activity that can be used in the study of nutraceuticals.
TN3794	Dehydroaglaiastatin		Others
	Dehydroaglaiastatin is a natural product of Aglaia, Meliaceae. The catalog number is TN3794 and the CAS number is 155595-93-0. Dehydroaglaiastatin can be used as a reference standard.		Others
TN2948	3'-Hydroxydehydroaglaiastatin		Others
	3'-Hydroxydehydroaglaiastatin is a natural product for research related to life sciences. The catalog number is TN2948 and the CAS number is 259143-58-3.		Others
TN5416	Threo-7-O-Methylguaiacylglycerol β-coniferyl ether
	threo-7-O-Methylguaiacylglycerol β-coniferyl ether is a natural product for research related to life sciences. The catalog number is TN5416 and the CAS number is 150333-85-0.
T28021	Meso-Dihydroguaiaretic acid
	meso-Dihydroguaiaretic acid is an LXR-α antagonist, it inhibits hepatic lipid accumulation by activating AMP-activated protein kinase in human HepG2 cells.
TN4008	Erythro-Guaiacylglycerol		Others
	erythro-Guaiacylglycerol is a natural product of Eucommia, Eucommiaceae. The catalog number is TN4008 and the CAS number is 38916-91-5. erythro-Guaiacylglycerol can be used as a reference standard.		Others
TN1581	Dihydroguaiaretic acid		COX , DNA/RNA Synthesis
	Dihydroguaiaretic acid has antioxidative activity, can significantly protect primary cultured neuronal cells against glutamate-induced oxidative stress.		COX , DNA/RNA Synthesis
T75530	Nardoguaianone J
	Nardoguaianone J, a guaiane-type compound isolated from the roots of Nardostachys chinensis, has been shown to enhance SERT activity [1][2].
TN4005	Erythro-Guaiacylglycerol-beta-O-4'-dehydrodisinapyl ether		Serine Protease
	erythro-Guaiacylglycerol-beta-O-4'-dehydrodisinapyl ether is a compound extracted from Brazilian rubber seed hulls and is an inhibitory activity against human leukocyte elastase (IC50 : 171 umol/L).		Serine Protease
TN1284	4β,12-Dihydroxyguaian-6,10-diene	4beta,12-dihydroxyguaian-6,10-diene	Others
	4beta,12-dihydroxyguaian-6,10-diene is a natural product from Alisma orientale.		Others
TN4246	Ifflaiamine		Others
	Ifflaiamine is a natural product from Flindersia ifflaiana F. Muell.		Others
TN5406	Threo-Guaiacylglycerol β-coniferyl ether
	Threo-Guaiacylglycerol beta-coniferyl ether displays significant inhibitory effects on NO production.
TN5145	Threo-Guaiacylglycerol		Others
	threo-Guaiacylglycerol is a natural product for research related to life sciences. The catalog number is TN5145 and the CAS number is 27391-16-8.		Others
TN5421	Threo-Guaiacylglycerol-β-O-4'-dehydrodisinapyl ether
	threo-Guaiacylglycerol-β-O-4'-dehydrodisinapyl ether is a natural product for research related to life sciences. The catalog number is TN5421 and the CAS number is 844637-85-0.
TN4007	Erythro-Guaiacylglycerol beta-sinapyl ether		Others
	erythro-Guaiacylglycerol beta-sinapyl ether is a natural product of Sambucus, Caprifoliaceae. The catalog number is TN4007 and the CAS number is 877875-96-2. erythro-Guaiacylglycerol beta-sinapyl ether can be used as a r...		Others
TN4006	Erythro-Guaiacylglycerol beta-sinapyl ether 7-O-glucoside		Others
	erythro-Guaiacylglycerol beta-sinapyl ether 7-O-glucoside is a natural product for research related to life sciences. The catalog number is TN4006 and the CAS number is 412029-03-9.		Others
T82031	Isoguaiacin
	Isoguaiacin, a natural product [1], exhibits (hass) the potential to be (to exist as) an (a) effective pharmacological agent due to its (its) ability to inhibit (the inhibition of) mushroom tyrosinase. This (The) inhibit...
TN4003	Erythro-Guaiacylglycerol beta-coniferyl ether		Glucosidase
	Erythro-Guaiacylglycerol beta-coniferyl ether is a compound that can be extracted from the stems and leaves of mung beans and has inhibitory effects on alpha-glucosidase with an EC50 value of 18.71 μM.		Glucosidase
TN6817	1αH,5αH-guaia-6-ene-4β,10β-diol
	1αH,5αH-guaia-6-ene-4β,10β-diol is a natural product.
TN2665	1alpha,4beta,10beta-Trihydroxyguaia-2,11(13)-dien-12,6alpha-olide		Others
	1alpha,4beta,10beta-Trihydroxyguaia-2,11(13)-dien-12,6alpha-olide is a natural product of Alisma, Alismataceae. The catalog number is TN2665 and the CAS number is 221148-94-3. 1alpha,4beta,10beta-Trihydroxyguaia-2,11(13)...		Others
T3888	Scopolin	Murrayin,Scopoloside	Sirtuin
	Scopolin (Scopoloside) formation is increased by the enhanced activity of PAL. Scopolin can reduce the clinical symptoms of rat AIA by inhibiting inflammation and angiogenesis, and this compound may be a potent agent for...		Sirtuin
T78492	D-Mannuronic acid sodium
	Sodium D-mannuronate, derived from the seaweed Macrocystis pyrifera, shows promise as a therapeutic agent in studies of autoimmune encephalomyelitis (EAE), adjuvant-induced arthritis (AIA), nephrotic syndrome, and acute ...