|
T40997 |
GLP-1R modulator C16
|
GLP-1R modulator C16 |
Glucagon Receptor
|
|
GLP-1R modulator C16 is a variable modulator that significantly increases the binding affinity of GLP-4. |
|
T37562 |
C16 Ceramide
|
N-acylsphingosine,C16 Ceramide (d18:1/16:0),Palmitoyl Ceramide,N-Palmitoylsphingosine |
p53
|
|
C16 Ceramide (Palmitoyl Ceramide) is a naturally occurring small molecule that activates p53 by directly and selectively binding to it. |
|
T9783 |
Boc-C16-COOH
|
|
PROTAC Linker
|
|
Boc-C16-COOH is a alkyl-chain-based PROTAC linker. Boc-C16-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
|
T16550 |
PKR-IN-C16
|
|
Others
|
|
PKR-IN-C16 is a specific protein kinase (PKR) inhibitor. PKR-IN-C16 is able to inhibit the autophosphorylation of PKR and unlock the translation blockade induced by PKR in primary neuronal cultures.PKR-IN-C16 binds the A... |
|
T35805 |
C16 Sphingomyelin (d18:1/16:0)
|
Sphingomyelin 16:0,N-Palmitoyl-D-sphingomyelin |
Endogenous Metabolite
|
|
C16 Sphingomyelin (d18:1/16:0) (N-Palmitoyl-D-sphingomyelin) is a phospholipid analog of phospholipid bilayer membranes, which can be used to study biofilm activity. |
|
T21547 |
PAF (C16)
|
C16-PAF |
ERK
,
MEK
,
MAPK
,
Endogenous Metabolite
|
|
PAF (C16) is a potent MAPK and MEK/ERK activator that induces increased vascular permeability. PAF (C16) (PAF (C16)) is a platelet-activating factor, a phospholipid-derived mediator and a ligand for PAF G protein-coupled... |
|
T37872 |
C16 Galactosylceramide (d18:1/16:0)
|
C16 Galactosylceramide (d18:1/16:0) |
|
|
C16 Galactosylceramide is a glycosphingolipid that contains a galactose moiety attached to a ceramide acylated with palmitic acid . |
|
T36859 |
C16 Globotriaosylceramide (d18:1/16:0)
|
C16 Globotriaosylceramide (d18:1/16:0) |
|
|
C16 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from C16 lactosylceramide . C16 globotriaosylceramide acts as a receptor for Shiga toxin in B cell-derived Raj... |
|
T69361 |
C16-Urea-Ceramide
|
|
|
|
C16-Urea-Ceramide s a neutral ceramidase (nCDase) inhibitor. It is a bioactive ceramide. |
|
T38180 |
C16 Phytoceramide (t18:0/16:0)
|
|
|
|
C16 Phytoceramide (t18:0/16:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. C16 Phytoceramide (t18:0/1... |
|
T17648 |
Boc-C16-NHS ester
|
|
Others
|
|
Boc-C16-NHS ester, an alkyl/ether-based PROTAC linker, enables the synthesis of PROTACs[1]. |
|
T35804 |
C16 Lactosylceramide (d18:1/16:0)
|
|
|
|
C16 Lactosylceramide is an endogenous bioactive sphingolipid. It forms membrane microdomains with Lyn kinase and the αi subunits of inhibitory G protein-coupled receptors (GPCRs), suggesting a role in cell signaling. Pla... |
|
T36149 |
13C C16 Sphingomyelin (d18:1/16:0)
|
|
|
|
13C C16 Sphingomyelin is an isotopically enriched form of C16 sphingomyelin with carbon-13 occurring on the fatty acid portion. It is intended for use as an internal standard for the quantification of C16 sphingomyelin b... |
|
T17470 |
Azide-PEG6-amido-C16-Boc
|
17-(Azide-PEG6-ethylcarbamoyl)heptadecanoic t-butyl ester |
Others
|
|
Azide-PEG6-amido-C16-Boc is an alkyl/ether-based PROTAC linker utilized in PROTAC synthesis[1]. |
|
T17437 |
Amino-PEG6-amido-C16-Boc
|
17-(Amino-PEG6-ethylcarbamoyl)heptadecanoic t-butyl ester |
Others
|
|
Amino-PEG6-amido-C16-Boc is a PEG-based PROTAC linker employed for the synthesis of PROTACs[1]. |
|
T17442 |
Amino-PEG9-amido-C16-Boc
|
17-(Amino-PEG9-ethylcarbamoyl)heptadecanoic t-butyl ester |
Others
|
|
Amino-PEG9-amido-C16-Boc is a polyethylene glycol (PEG)-based linker utilized for the synthesis of proteolysis-targeting chimeras (PROTACs)[1]. |
|
T17438 |
Amino-PEG6-amido-C16-COOH
|
17-(Amino-PEG6-ethylcarbamoyl)heptadecanoic acid |
Others
|
|
Amino-PEG6-amido-C16-COOH, a PEG-based PROTAC linker, facilitates the synthesis of PROTACs[1]. |
|
T17472 |
Azide-PEG9-amido-C16-Boc
|
17-(Azide-PEG9-ethylcarbamoyl)heptadecanoic t-butyl ester |
Others
|
|
Azide-PEG9-amido-C16-Boc is an alkyl/ether-based PROTAC linker with utility in PROTAC synthesis [1]. |
|
TF0041 |
PMAL-C16
|
|
|
|
PMAL-C16 has a wide range of applications in life science related research. |
|
T37454 |
C16 dihydro Ceramide (d18:0/16:0)
|
Ceramide (d18:0/16:0),Cer(d18:0/16:0),N-hexadecanoyl-D-erythro-Dihydrosphingosine,N-Palmitoyl Sphinganine |
|
|
C16 dihydro Ceramide is a bioactive sphingolipid and precursor in the de novo synthesis of C16 ceramide (d18:0/16:0) that lacks the 4,5-trans double bond.[1] C16 dihydro Ceramide (0-46 nM) inhibits C16 ceramide-induced m... |
|
T74304 |
C16 PEG-Ceramide
|
|
|
|
C16 PEG-Ceramide, a polyethylene glycolylated ceramide, serves as a lipid carrier for delivery and induces autophagy. It is utilized in cancer research [1] [2]. |
|
T73127 |
C16-K-cBB1
|
|
|
|
C16-K-cBB1 is a potent, selective antimicrobial agent effective against Methicillin-resistant Staphylococcus aureus (MRSA), demonstrated by its minimal inhibitory concentration (MIC) of 1 µg/mL. This compound exhibits ex... |
|
T14185 |
Alkynyl Palmitic Acid
|
|
Others
,
PROTAC Linker
|
|
Alkynyl Palmitic Acid is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis. |
|
T37741 |
N-hexadecanoyl-L-Homoserine lactone
|
C16-HSL,N-palmitoyl-L-Homoserine,N-hexadecanoyl-L-Homoserine lactone |
|
|
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.[1] This regulatory process manifests itself with a variety of phenotypes including biofilm fo... |
|
T29350 |
2-Hexyldecanoic acid
|
Pentadecane-7-carboxylic Acid,Isopalmitic Acid,7-Pentadecanecarboxylic acid,C16 Guerbet fatty acid,2-Hexyldecansaeure |
|
|
2-Hexyldecanoic acid is a biochemical. |
|
T36205 |
Methylcarbamyl PAF C-16
|
|
|
|
Methylcarbamyl PAF C-16 is a stable analog of PAF C-16 with a half-life greater than 100 minutes in platelet poor plasma due to its resistance to degradation by PAF-AH. It is nearly equipotent with PAF C-16 in its abilit... |
|
T37268 |
PAF C-16 Carboxylic Acid
|
|
|
|
PAF C-16 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the remodeling" and 'de novo' pathways. It is a potent mediator of neutrophil migration and the production o... |
|
T8929 |
BC1618
|
2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]- |
Mitophagy
,
Others
,
E1/E2/E3 Enzyme
,
AMPK
|
|
BC1618 (2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-) is an orally active Fbxo48 inhibitor that stimulates Ampk-dependent signaling. It promotes mitochondrial fission, promotes autophagy and imp... |
|
T40141 |
Palmitic acid-13C16 sodium
|
Palmitic acid-13C16 sodium |
|
|
Palmitic acid-13C16 sodium, a 13C-labeled form of the naturally occurring saturated fatty acid Palmitic acid sodium, is prevalent in animals and plants. This compound can trigger the expression of glucose-regulated prote... |
|
T38693 |
TRC160334
|
TRC160334 |
|
|
TRC160334 is a hydroxylase inhibitor of hypoxia-inducible factor (HIF). It is employed in research about ischemia/reperfusion injury. |
|
T16351 |
NSC16168
|
|
Estrogen/progestogen Receptor
|
|
NSC16168 inhibits DNA repair and potentiates CDDP efficacy in cancer. NSC16168 is a specific ERCC1-XPF inhibitor (IC50: 0.42 μM). |
|
T70687 |
UNC1666
|
|
|
|
UNC1666 is a dual ATP-competitive small molecule tyrosine kinase inhibitor, which potently diminishes Mer and Flt3 phosphorylation in AML. |
|
T71044 |
TRC160334 sodium
|
|
|
|
TRC160334 is a HIF hydroxylases inhibitor. |
|
T24150 |
HR22C16
|
HR-22-C-16,HR 22 C 16 |
|
|
HR22C16 is an effective, selective, and cell-permeable mitotic kinesin Eg5 inhibitor. |
|
T83842 |
LHC165 hydrate
|
|
|
|
LHC165, a toll-like receptor 7 (TLR7) agonist, stimulates the immune system's response by activating TLR7. |
|
T37563 |
C22 Ceramide (d18:1/22:0)
|
Cer(d18:1/22:0),C22 Ceramide,Ceramide (d18:1/22:0) |
|
|
C22 Ceramide (d18:1/22:0) (C22 Ceramide), a long-chain ceramide containing behenic acid, is an endogenous bioactive sphingolipid.C22-Ceramide specifically inhibits MCSR and reduces C16 ceramide channel formation in isola... |
|
T37955 |
Sphingosine-1-phosphate (d16:1)
|
Sphingosine-1-phosphate (d16:1) |
|
|
C16 Sphingosine-1-phosphate (C16 S1P) is a derivative of sphingosine-1-phosphate that binds to S1P1/EDG-1, S1P3/EDG-3, and S1P2/EDG-5 receptors with affinities of 115%, 83%, and 103%, respectively, relative to S1P in CHO... |
|
T36468 |
ARN14988
|
|
|
|
ARN14988 is a potent inhibitor of acid ceramidase (IC50 = 12.8 nM for the human enzyme). It inhibits acid ceramidase activity and increases levels of C16 dihydro ceramide and C16 ceramide in A375, G361, M14, MeWo, MNT-1,... |
|
T36860 |
C22 Sphingomyelin (d18:1/22:0)
|
C22 Sphingomyelin (d18:1/22:0) |
|
|
C22 Sphingomyelin is a naturally occurring form of sphingomyelin . Plasma levels of C22 sphingomyelin positively correlate with hepatic steatosis severity in patients with chronic hepatitis C virus (HCV). C22 Sphingomyel... |
|
T37337 |
N-3-oxo-hexadecanoyl-L-Homoserine lactone
|
|
|
|
N-3-oxo-hexadecanoyl-L-Homoserine lactone is an unusual, substituted, long-chain N-acyl-homoserine lactone (AHL) produced by some bacteria, including strains of Agrobacterium vitis and Pseudomonas. Like other AHLs, this ... |
|
T36321 |
C6 Urea Ceramide
|
|
|
|
C6 urea ceramide is an inhibitor of neutral ceramidase.1 It increases total ceramide levels in wild-type mouse embryonic fibroblasts (MEFs) and in HT-29 colon cancer cells but not in MEFs lacking neutral ceramidase. It i... |
|
T37336 |
N-3-oxo-hexadec-11(Z)-enoyl-L-Homoserine lactone
|
|
|
|
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm forma... |
|
T37736 |
N-cis-hexadec-9Z-enoyl-L-Homoserine lactone
|
N-(2-oxotetrahydrofuran-3S-yl) Palmitoleyl Amide,N-cis-hexadec-9Z-enoyl-L-Homoserine lactone |
|
|
Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density.[1] This regulatory process manifests itself with a variety of phenotypes including biofilm f... |
|
T36929 |
Pal-KTTKS (acetate)
|
|
|
|
Pal-KTTKS is a lipidated pentapeptide consisting of a fragment of the type I collagen C-terminal propeptide conjugated to palmitic acid .1 It increases collagen production in human corneal and dermal fibroblasts when use... |
