| T6S0052 |
Chelerythrine
|
Toddalin,Broussonpapyrine,Cheleritrine |
Apoptosis
,
BCL
,
PKC
,
Autophagy
|
|
1. Chelerythrine (Broussonpapyrine) may have antimanic effect . 2. Chelerythrine can inhibit telomerase activity. 3. Chelerythrine is a well-known protein kinase C inhibitor . 4. Chelerythrine has potential antiprolifera... |
| T3419 |
Chelerythrine chloride
|
|
Apoptosis
,
BCL
,
PKC
,
Autophagy
|
|
Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect to ATP. |
| T3S0057 |
Dihydrochelerythrine
|
12,13-Dihydrochelerythrine |
Antifungal
|
|
1. Dihydrochelerythrine (12,13-Dihydrochelerythrine) is nontoxic up to 5μM concentration. 2. Dihydrochelerythrine has antifungal activity against pathogenic plant fungi. 3. Dihydrochelerythrine has potential application ... |
| T2S0058 |
6-Ethoxychelerythrine
|
Ethoxychelerythrin |
Antibacterial
|
|
6-Ethoxychelerythrine (Ethoxychelerythrin) has anti-bacterial activity, it exhibited strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus (MRSA). |
| TN1991 |
Norchelerythrine
|
|
Antifection
|
|
Norchelerythrine shows significant inhibitory activity against Staphylococcus aureus ATCC 6538 with MIC values ranging from 12.5 to 50 ug/mL. It exhibits strong antifeeding activity in a concentration-dependant manner wi... |
| TN3152 |
6-Acetonyldihydrochelerythrine
|
|
ERK
,
BCL
,
Akt
,
HIV Protease
,
PPAR
,
p53
|
|
6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities, it exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therapeutic Index) values of 1.77 microg/mL and 14.6, respectively... |
| T83281 |
6-(1-Hydroxyethyl)-5,6-dihydrochelerythrine
|
|
|
|
6-(1-Hydroxyethyl)-5,6-dihydrochelerythrine, an alkaloid, markedly alters the characteristics of cellular organelles—specifically, early endosomes, mitochondria, and autophagosomes—in Parkinson’s Disease patient-derived ... |
| TN4725 |
Oxychelerythrine
|
|
Antifection
|
|
Oxychelerythrine shows high modulatory activity enhancing the susceptibility of the S. aureus ATCC 6538 to all the tested antibiotics from two to four-fold. It also shows antifeeding activities against Tribolium castaneu... |
