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Search Results for " Cytosine "

ターゲット

40

阻害剤

10

天然化合物

10

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1

ライブラリー

カタログ番号 製品名 別名 ターゲット
T35363 HM-cytosine 5hmC,5-Hydroxymethylcytosine Others
HM-cytosine (5hmC) is a naturally occurring component of mammalian genomic DNA and is thought to be the sixth base of DNA [1]. HM-cytosine is an intermediate metabolite for demethylation of active DNA [2]. HM-cytosine is...
T67797 DDG-39 1-(2,3-dideoxy-2-fluoropentofuranosyl)cytosine Antiviral , HBV , HIV Protease
DDG-39 (1-(2,3-dideoxy-2-fluoropentofuranosyl)cytosine) possesses antiviral activity with potent and selective anti-HIV-1 and HBV activity in cell culture. The average antiviral IC50 is 0.61 μM.
T1272L Cytarabine hydrochloride Ara-C hydrochloride,Cytosine Arabinoside hydrochloride DNA/RNA Synthesis
Cytarabine hydrochloride (Ara-C hydrochloride) is a nucleoside analog that causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC 50 of 16 nM. Cytarabine hydrochloride ...
T15009 Elacytarabine 5'-Oleoyl cytosine arabinoside,5'-O-(Elaidoyl) 1-beta-D-arabinofuranosylcytosine,5'-Oleoyl cytarabine,CP 4055 Others
Elacytarabine (M7594 0037), a lipid-conjugated derivative of the nucleoside analog cytarabine, is an antineoplastic drug. It has cytotoxicity in solid tumors.
T83937 Tricyclic cytosine tC
Tricyclic cytosine (tC) is a fluorescent analog of cytosine designed for RNA imaging within live cells, facilitating the study of RNA synthesis, degradation, and trafficking with single-cell precision through confocal im...
TNU1345 1-(alpha-L-Threofuranosyl)cytosine
1-(alpha-L-Threofuranosyl)cytosine is a Nucleoside Derivative - L-nucleoside.
TNU1587 N4-Benzoyl-7’-OH-N-DMTr morpholino cytosine
N4-Benzoyl-7'-OH-N-DMTr morpholino cytosine is a Nucleoside Derivative - Morpholino nucleoside.
TNU0597 1-(2,3-Dideoxy-β-D-erythro-hexo pyranosyl)cytosine
1-(2,3-Dideoxy-β-D-erythro-hexo pyranosyl)cytosine is a useful organic compound for research related to life sciences. The catalog number is TNU0597 and the CAS number is 136020-18-3.
TNU1598 N-DMTr-N4-benzoyl-morpholino-cytosine-5’-O-phosphoramidite
N-DMTr-N4-benzoyl-morpholino-cytosine-5'-O-phosphoramidite is a Nucleoside Phosphoramidite.
TNU1506 1-[[2-Hydroxy-1-(hydroxy   methyl)ethoxy]methyl]cytosine
1-[[2-Hydroxy-1-(hydroxy methyl)ethoxy]methyl]cytosine is a Nucleoside Derivative - Acyclic nucleoside.
TNU1658 N4-Benzoyl-7’-OH-N-DMTr morpholino 5-methyl cytosine
N4-Benzoyl-7’-OH-N-DMTr morpholino 5-methyl cytosine is a useful organic compound for research related to life sciences and the catalog number is TNU1658.
TNU1461 N4-Benzoyl-7’-OH-N-trityl morpholino 5-methyl cytosine
N4-Benzoyl-7’-OH-N-trityl morpholino 5-methyl cytosine is a useful organic compound for research related to life sciences and the catalog number is TNU1461.
TNU1622 1-(2,3-Dideoxy-2,3-didehydro-a-D-erythro-hexo pyranosyl) cytosine
1-(2,3-Dideoxy-2,3-didehydro-a-D-erythro-hexo pyranosyl) cytosine is a useful organic compound for research related to life sciences. The catalog number is TNU1622 and the CAS number is 199599-71-8.
TNU1591 5-Aza-9-(b-D-xylofuranosyl) cytosine; 5-Aza-xylo-cytidine
5-Aza-9-(b-D-xylofuranosyl) cytosine; 5-Aza-xylo-cytidine is a useful organic compound for research related to life sciences and the catalog number is TNU1591.
T5198 Bobcat339 Bobcat339 hydrochloride DNA Methyltransferase
Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.
TNU1623 N4-Benzoyl-1-(6-O-DMTr-2,3-dideoxy-beta-D-erythro-hexopyranosyl)cytosine
N4-Benzoyl-1-(6-O-DMTr-2,3-dideoxy-beta-D-erythro-hexopyranosyl)cytosine is a useful organic compound for research related to life sciences. The catalog number is TNU1623 and the CAS number is 145594-00-9.
TNU1624 Beta-D-homoDNA-C(Bz)-phosphorami dite; N4-Benzoyl-1-[6-O-DMTr-2,3-dideoxy-4-(O-CED-phosphoramitidyl)-beta-D-erythro-hexopyranosyl)cytosine
Beta-D-homoDNA-C(Bz)-phosphorami dite; N4-Benzoyl-1-[6-O-DMTr-2,3-dideoxy-4-(O-CED-phosphoramitidyl)-beta-D-erythro-hexopyranosyl)cytosine is a useful organic compound for research related to life sciences and the catalo...
T7518 Deoxycytidine triphosphate trisodium salt 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite , Antibiotic
Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) contributes to antibiotic lethality in stationary-phase mycobacteria.
T10019 1-Methylcytosine 1-methylcytosin,4-amino-1-methylpyrimidin-2(1H)-one,N-Methylcytosine Nucleoside Antimetabolite/Analog
1-Methylcytosine (4-amino-1-methylpyrimidin-2(1H)-one) is a methylated form of the cytosine and can be used as the nucleobase of hachimoji DNA paired with isoguanine.
T7466 5-Bromocytosine Others
5-Bromocytosine can be used in the synthesis of cross-link products under anaerobic and aerobic conditions.
TNU0521 1-(b-D-Xylofuranosyl)-5-methylcytosine
Nucleoside Derivatives –5-Modified pyrimidine nucleosides;Xylo-nucleosides
TNU1448 NovelN4-Benzoyl-7’-O-(4,4’-dimethoxytrityl oxy)morpholinocytosine
novelN4-Benzoyl-7'-O-(4,4'-dimethoxytrityl oxy)morpholinocytosine is a Nucleoside Derivative - Morpholino nucleoside.
TNU1659 N4-Benzoyl-N-DMTr- morpholino-5-methylcytosine-5’-O-phosphoramidite
N4-Benzoyl-N-DMTr- morpholino-5-methylcytosine-5’-O-phosphoramidite is a useful organic compound for research related to life sciences and the catalog number is TNU1659.
T30117 Ara-fluorocytosine NSC529180,NSC 529180,NSC-529180
Ara-fluorocytosine is a biochemical.
TNU1628 1-[3’-O-[(4,4’-dimethoxytriphenyl)methyl]-a-L-threofuranosyl]-N4-benzoylcytosine
1-[3’-O-[(4,4’-dimethoxytriphenyl)methyl]-a-L-threofuranosyl]-N4-benzoylcytosine is a useful organic compound for research related to life sciences. The catalog number is TNU1628 and the CAS number is 325683-91-8.
T29453 5-Formylcytosine
5-formylcytosine (5FC) is a rare base found in mammalian DNA. It participates in active DNA demethylation, changes DNA double helix structure, and reduces the transcription rate and substrate specificity of RNA polymeras...
TNU0629 5-Iodocytosine
5-Iodocytosine is a Heterocyclic compound-pyrimidine, intermediate and building block, halo-.
TNU0642 N4-Benzoyl-7’-OH-N-trityl morpholinocytosine
N4-Benzoyl-7'-OH-N-trityl morpholinocytosine is a Morpholino-nucleoside.
T34399 Rovatirelin KPS-0373,S0373,S-0373,S 0373 AChE
Rovatirelin (S-0373) is a newly synthesized thyrotropin-releasing hormone (TRH) analog that ameliorates cytosine arabinoside-induced motor dysfunction in a rat model of spinal cerebellar degeneration via acetylcholine an...
T14578 Biotin Hydrazide Others
Biotin Hydrazide is a carbonyl-reactive biotinylation reagent, which is a carbonyl probe. Biotin Hydrazide is a great choice for labeling mouse monoclonal antibodies, lectins, sugars, unpaired cytosine residues in nuclei...
T0251 Gemcitabine NSC 613327,LY188011 Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Autophagy
Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor and antimetabolic activities. Gemcitabine induces autophagy and apoptosis.
TNU0425 2’-Deoxy-2’-fluoro-β-D-arabinocytidine hydrochloride DNA Methyltransferase
2’-Deoxy-2’-fluoro-β-D-arabinocytidine hydrochloride is a cytosine nucleoside analog with inhibitory effects on DNA methyltransferase , with potential antimetabolic and antitumor activity.
T6069 Gemcitabine hydrochloride Gemcitabine HCl,Gemzar,LY188011,LY 188011 hydrochloride Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Autophagy
Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor and antimetabolic activities. Gemcitabine induces autophagy a...
T25286 DANP
DANP is a bulge base recognition probe. It is a potent and specific ligand of the single cytosine and thymine bulges with exclusively 1:1 stoichiometry.
T40560 Benzyl selenocyanate
Benzyl selenocyanate is a chemopreventive agent that effectively inhibits chemically induced tumors at both initiation and postinitiation stages in animal models. It acts as a potent inhibitor of DNA (cytosine-5)-methylt...
T68207 Elsamitrucin
Elsamitrucin is a heterocyclic antineoplastic antibiotic isolated from the bacterium Actinomycete strain J907-21. Elsamitrucin intercalates into DNA at guanine-cytosine (G-C)-rich sequences and inhibits topoisomerase I a...
T40345 AV-153
AV-153 is a 1,4-dihydropyridine derivative with antimutagenic properties. It intercalates into DNA at single strand breaks, resulting in reduced DNA damage and stimulation of DNA repair in human cells in vitro. AV-153 al...
T37031 Quinacrine mustard hydrochloride Quinacrine mustard HCl Autophagy
Quinacrine mustard hydrochloride is a fluorescent dye and polycyclic aromatic agent that acts as a mutagen to induce mutants in bacteria.Quinacrine mustard hydrochloride selectively binds to adenine-thymine (AT) base pai...
T61012 Bobcat339 hydrochloride
Bobcat339 hydrochloride can be used in the field of epigenetics and as a starting point for new therapeutics targeting DNA methylation and gene transcription. Bobcat339 hydrochloride is a potent and selective cytosine-ba...
T60649 AV-153 free base
AV-153 free base is a 1,4-dihydropyridine (1,4-DHP) derivative. AV-153 free base is an antimutagenic with anti-cancer activity. AV-153 free base interacts with cytosine and thymine and has an influence on poly(ADP)ribosy...

Compounds

HM-cytosine
T35363
Synonym: 5hmC,5-Hydroxymethylcytosine
Target: Others
DDG-39
T67797
Synonym: 1-(2,3-dideoxy-2-fluoropentofuranosyl)cytosine
Target: Antiviral, HBV, HIV Protease
Cytarabine hydrochloride
T1272L
Synonym: Ara-C hydrochloride,Cytosine Arabinoside hydrochloride
Target: DNA/RNA Synthesis
Elacytarabine
T15009
Synonym: 5'-Oleoyl cytosine arabinoside,5'-O-(Elaidoyl) 1-beta-D-arabinofuranosylcytosine,5'-Oleoyl cytarabine,CP 4055
Target: Others
Tricyclic cytosine tC
T83937
Synonym:
Target:
1-(alpha-L-Threofuranosyl)cytosine
TNU1345
Synonym:
Target:
N4-Benzoyl-7’-OH-N-DMTr morpholino cytosine
TNU1587
Synonym:
Target:
1-(2,3-Dideoxy-β-D-erythro-hexo pyranosyl)cytosine
TNU0597
Synonym:
Target:
N-DMTr-N4-benzoyl-morpholino-cytosine-5’-O-phosphoramidite
TNU1598
Synonym:
Target:
1-[[2-Hydroxy-1-(hydroxy   methyl)ethoxy]methyl]cytosine
TNU1506
Synonym:
Target:
N4-Benzoyl-7’-OH-N-DMTr morpholino 5-methyl cytosine
TNU1658
Synonym:
Target:
N4-Benzoyl-7’-OH-N-trityl morpholino 5-methyl cytosine
TNU1461
Synonym:
Target:
1-(2,3-Dideoxy-2,3-didehydro-a-D-erythro-hexo pyranosyl) cytosine
TNU1622
Synonym:
Target:
5-Aza-9-(b-D-xylofuranosyl) cytosine; 5-Aza-xylo-cytidine
TNU1591
Synonym:
Target:
Bobcat339
T5198
Synonym: Bobcat339 hydrochloride
Target: DNA Methyltransferase
N4-Benzoyl-1-(6-O-DMTr-2,3-dideoxy-beta-D-erythro-hexopyranosyl)cytosine
TNU1623
Synonym:
Target:
Beta-D-homoDNA-C(Bz)-phosphorami dite; N4-Benzoyl-1-[6-O-DMTr-2,3-dideoxy-4-(O-CED-phosphoramitidyl)-beta-D-erythro-hexopyranosyl)cytosine
TNU1624
Synonym:
Target:
Deoxycytidine triphosphate trisodium salt
T7518
Synonym: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI
Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Endogenous Metabolite, Antibiotic
1-Methylcytosine
T10019
Synonym: 1-methylcytosin,4-amino-1-methylpyrimidin-2(1H)-one,N-Methylcytosine
Target: Nucleoside Antimetabolite/Analog
5-Bromocytosine
T7466
Synonym:
Target: Others
1-(b-D-Xylofuranosyl)-5-methylcytosine
TNU0521
Synonym:
Target:
novelN4-Benzoyl-7’-O-(4,4’-dimethoxytrityl oxy)morpholinocytosine
TNU1448
Synonym:
Target:
N4-Benzoyl-N-DMTr- morpholino-5-methylcytosine-5’-O-phosphoramidite
TNU1659
Synonym:
Target:
Ara-fluorocytosine
T30117
Synonym: NSC529180,NSC 529180,NSC-529180
Target:
1-[3’-O-[(4,4’-dimethoxytriphenyl)methyl]-a-L-threofuranosyl]-N4-benzoylcytosine
TNU1628
Synonym:
Target:
5-Formylcytosine
T29453
Synonym:
Target:
5-Iodocytosine
TNU0629
Synonym:
Target:
N4-Benzoyl-7’-OH-N-trityl morpholinocytosine
TNU0642
Synonym:
Target:
Rovatirelin
T34399
Synonym: KPS-0373,S0373,S-0373,S 0373
Target: AChE
Biotin Hydrazide
T14578
Synonym:
Target: Others
Gemcitabine
T0251
Synonym: NSC 613327,LY188011
Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Autophagy
2’-Deoxy-2’-fluoro-β-D-arabinocytidine hydrochloride
TNU0425
Synonym:
Target: DNA Methyltransferase
Gemcitabine hydrochloride
T6069
Synonym: Gemcitabine HCl,Gemzar,LY188011,LY 188011 hydrochloride
Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Autophagy
DANP
T25286
Synonym:
Target:
Benzyl selenocyanate
T40560
Synonym:
Target:
Elsamitrucin
T68207
Synonym:
Target:
AV-153
T40345
Synonym:
Target:
Quinacrine mustard hydrochloride
T37031
Synonym: Quinacrine mustard HCl
Target: Autophagy
Bobcat339 hydrochloride
T61012
Synonym:
Target:
AV-153 free base
T60649
Synonym:
Target:
カタログ番号 製品名 別名 ターゲット
T4832 Cytosine 6-Aminopyrimidin-2(1H)-one,4-Amino-2-hydroxypyrimidine,Cytosinimine Endogenous Metabolite
Cytosine (6-Aminopyrimidin-2(1H)-one) is a pyrimidine base that is a fundamental unit of nucleic acids. The deamination of cytosine alone is apparent and the nucleotide of cytosine is the prime mutagenic nucleotide in le...
T1272 Cytarabine Ara-C,Cytosine Arabinoside,Cytosine β-D-arabinofuranoside,Arabinocytidine Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite , Autophagy , HSV
Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM). Cytarabine inhibits DNA polymerase and induces cell cycle arrest, autophagy, and apoptosis. Cytarabine has antitumor activity.
T1591L Cytidine Cytosine-1-β-D-ribofuranoside,Cytosine β-D-riboside Nucleoside Antimetabolite/Analog , Endogenous Metabolite
Cytidine (Cytosine-1-β-D-ribofuranoside) is a pyrimidine nucleoside comprised of a cytosine bound to ribose via a beta-N1-glycosidic bond. Cytidine is a precursor for uridine. Both cytidine and uridine are utilized in RN...
T4758 2'-Deoxycytidine Cytosine deoxyribonucleoside,2'-Deoxycytidine monohydrate,2(1H)-Pyrimidinone,Cytosine deoxyriboside,Deoxyribose cytidine,Deoxycytidine Endogenous Metabolite
2'-Deoxycytidine (Deoxyribose cytidine) is one of the principal nucleosides of DNA composed of cytosine and deoxyribose. A nucleoside consists of only a pentose sugar linked to a purine or pyrimidine base, without a phos...
T7520 Deoxycytidine triphosphate Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite
Deoxycytidine triphosphate is a nucleoside triphosphate.It is a raw material in DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
T0986 Flucytosine 5-Fluorocytosine,Ro 2-9915,Fluorocytosine,NSC 103805 DNA/RNA Synthesis , Antibiotic , Antifungal
Flucytosine (NSC 103805) is a pyrimidine compound and a fluorinated cytosine analog exhibiting antifungal activity.
T5270 5-Methylcytosine Others , DNA/RNA Synthesis , Endogenous Metabolite
5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA. In animals, the DNA methylation of cytosine to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In plants, the methylated...
T64878 2-O-Methylcytosine
2-O-Methylcytosine is a natural product for research related to life sciences. The catalog number is T64878 and the CAS number is 3289-47-2.
T4809 Pyrimidine Metadiazine Others , Endogenous Metabolite
Pyrimidine (Metadiazine)s are heterocyclic, six-membered, nitrogen-containing carbon ring structures, with uracil, cytosine and thymine being the basal structures of ribose-containing nucleosides (uridine, cytidine, and ...
TMO2752 Cytidine 5'-monophosphate 5'-Cytidylic acid,5'-CMP,Cytidylic Acid Others , Endogenous Metabolite
Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide, one of the basic units that make up RNA. It consists of nucleobase cytosine, pentose ribose and phosphate groups.

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPH-00607 Cytosine deaminase Protein, E. coli, Recombinant (His & SUMO) E. coli E. coli
Catalyzes the hydrolytic deamination of cytosine to uracil. Is involved in the pyrimidine salvage pathway, which allows the cell to utilize cytosine for pyrimidine nucleotide synthesis. Is also able to catalyze deaminati...
TMPH-02908 AICDA Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation (SHM), gene conversion, and class-switch recombination (CSR) in B-lymphocytes by deaminating C to U during transcription of Ig-variable (...
TMPH-01677 MBD2 Protein, Human, Recombinant (His & KSI) Human E. coli
Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcrip...
TMPY-01306 DNMT2 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
DNMT2, also known as tRNA (cytosine-5-)-methyltransferase, DNA methyltransferase homolog HsaIIP, and TRDMT1, is a member of the DNA methyltransferase family of enzymes. DNMT2 enzymes have been widely conserved during evo...
TMPH-01235 APOBEC3A Protein, Human, Recombinant (His & SUMO) Human E. coli
DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus...
TMPH-02112 SMUG1 Protein, Human, Recombinant (His & SUMO) Human E. coli
Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The act...
TMPH-01801 NME2 Protein, Human, Recombinant (His & Myc) Human E. coli
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Negativ...
TMPY-01285 METTL11A Protein, Human, Recombinant Human E. coli
Methyltransferase-like protein 11A, also known as METTL11A, is a member of the methyltransferase superfamily and METTL11 family. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a don...
TMPY-01284 METTL11A Protein, Human, Recombinant (GST) Human E. coli
Methyltransferase-like protein 11A, also known as METTL11A, is a member of the methyltransferase superfamily and METTL11 family. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a don...
TMPY-02000 UNG Protein, Human, Recombinant (GST) Human E. coli
Isoform 1 is widely expressed with the highest expression in skeletal muscle, heart and testicles. Isoform 2 has the highest expression levels in tissues containing proliferating cells. Uracil-DNA glycosylase exists in t...
カタログ番号 製品名
L3510 Methylation Compound Library

128 compounds
128 methylation-related compounds that can be used for high-throughput and high-content screening.