40
10
10
1
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T35363 | HM-cytosine | 5hmC,5-Hydroxymethylcytosine | Others |
HM-cytosine (5hmC) is a naturally occurring component of mammalian genomic DNA and is thought to be the sixth base of DNA [1]. HM-cytosine is an intermediate metabolite for demethylation of active DNA [2]. HM-cytosine is... | |||
T67797 | DDG-39 | 1-(2,3-dideoxy-2-fluoropentofuranosyl)cytosine | Antiviral , HBV , HIV Protease |
DDG-39 (1-(2,3-dideoxy-2-fluoropentofuranosyl)cytosine) possesses antiviral activity with potent and selective anti-HIV-1 and HBV activity in cell culture. The average antiviral IC50 is 0.61 μM. | |||
T1272L | Cytarabine hydrochloride | Ara-C hydrochloride,Cytosine Arabinoside hydrochloride | DNA/RNA Synthesis |
Cytarabine hydrochloride (Ara-C hydrochloride) is a nucleoside analog that causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC 50 of 16 nM. Cytarabine hydrochloride ... | |||
T15009 | Elacytarabine | 5'-Oleoyl cytosine arabinoside,5'-O-(Elaidoyl) 1-beta-D-arabinofuranosylcytosine,5'-Oleoyl cytarabine,CP 4055 | Others |
Elacytarabine (M7594 0037), a lipid-conjugated derivative of the nucleoside analog cytarabine, is an antineoplastic drug. It has cytotoxicity in solid tumors. | |||
T83937 | Tricyclic cytosine tC | ||
Tricyclic cytosine (tC) is a fluorescent analog of cytosine designed for RNA imaging within live cells, facilitating the study of RNA synthesis, degradation, and trafficking with single-cell precision through confocal im... | |||
TNU1345 | 1-(alpha-L-Threofuranosyl)cytosine | ||
1-(alpha-L-Threofuranosyl)cytosine is a Nucleoside Derivative - L-nucleoside. | |||
TNU1587 | N4-Benzoyl-7’-OH-N-DMTr morpholino cytosine | ||
N4-Benzoyl-7'-OH-N-DMTr morpholino cytosine is a Nucleoside Derivative - Morpholino nucleoside. | |||
TNU0597 | 1-(2,3-Dideoxy-β-D-erythro-hexo pyranosyl)cytosine | ||
1-(2,3-Dideoxy-β-D-erythro-hexo pyranosyl)cytosine is a useful organic compound for research related to life sciences. The catalog number is TNU0597 and the CAS number is 136020-18-3. | |||
TNU1598 | N-DMTr-N4-benzoyl-morpholino-cytosine-5’-O-phosphoramidite | ||
N-DMTr-N4-benzoyl-morpholino-cytosine-5'-O-phosphoramidite is a Nucleoside Phosphoramidite. | |||
TNU1506 | 1-[[2-Hydroxy-1-(hydroxy methyl)ethoxy]methyl]cytosine | ||
1-[[2-Hydroxy-1-(hydroxy methyl)ethoxy]methyl]cytosine is a Nucleoside Derivative - Acyclic nucleoside. | |||
TNU1658 | N4-Benzoyl-7’-OH-N-DMTr morpholino 5-methyl cytosine | ||
N4-Benzoyl-7’-OH-N-DMTr morpholino 5-methyl cytosine is a useful organic compound for research related to life sciences and the catalog number is TNU1658. | |||
TNU1461 | N4-Benzoyl-7’-OH-N-trityl morpholino 5-methyl cytosine | ||
N4-Benzoyl-7’-OH-N-trityl morpholino 5-methyl cytosine is a useful organic compound for research related to life sciences and the catalog number is TNU1461. | |||
TNU1622 | 1-(2,3-Dideoxy-2,3-didehydro-a-D-erythro-hexo pyranosyl) cytosine | ||
1-(2,3-Dideoxy-2,3-didehydro-a-D-erythro-hexo pyranosyl) cytosine is a useful organic compound for research related to life sciences. The catalog number is TNU1622 and the CAS number is 199599-71-8. | |||
TNU1591 | 5-Aza-9-(b-D-xylofuranosyl) cytosine; 5-Aza-xylo-cytidine | ||
5-Aza-9-(b-D-xylofuranosyl) cytosine; 5-Aza-xylo-cytidine is a useful organic compound for research related to life sciences and the catalog number is TNU1591. | |||
T5198 | Bobcat339 | Bobcat339 hydrochloride | DNA Methyltransferase |
Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a. | |||
TNU1623 | N4-Benzoyl-1-(6-O-DMTr-2,3-dideoxy-beta-D-erythro-hexopyranosyl)cytosine | ||
N4-Benzoyl-1-(6-O-DMTr-2,3-dideoxy-beta-D-erythro-hexopyranosyl)cytosine is a useful organic compound for research related to life sciences. The catalog number is TNU1623 and the CAS number is 145594-00-9. | |||
TNU1624 | Beta-D-homoDNA-C(Bz)-phosphorami dite; N4-Benzoyl-1-[6-O-DMTr-2,3-dideoxy-4-(O-CED-phosphoramitidyl)-beta-D-erythro-hexopyranosyl)cytosine | ||
Beta-D-homoDNA-C(Bz)-phosphorami dite; N4-Benzoyl-1-[6-O-DMTr-2,3-dideoxy-4-(O-CED-phosphoramitidyl)-beta-D-erythro-hexopyranosyl)cytosine is a useful organic compound for research related to life sciences and the catalo... | |||
T7518 | Deoxycytidine triphosphate trisodium salt | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI | Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite , Antibiotic |
Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) contributes to antibiotic lethality in stationary-phase mycobacteria. | |||
T10019 | 1-Methylcytosine | 1-methylcytosin,4-amino-1-methylpyrimidin-2(1H)-one,N-Methylcytosine | Nucleoside Antimetabolite/Analog |
1-Methylcytosine (4-amino-1-methylpyrimidin-2(1H)-one) is a methylated form of the cytosine and can be used as the nucleobase of hachimoji DNA paired with isoguanine. | |||
T7466 | 5-Bromocytosine | Others | |
5-Bromocytosine can be used in the synthesis of cross-link products under anaerobic and aerobic conditions. | |||
TNU0521 | 1-(b-D-Xylofuranosyl)-5-methylcytosine | ||
Nucleoside Derivatives –5-Modified pyrimidine nucleosides;Xylo-nucleosides | |||
TNU1448 | NovelN4-Benzoyl-7’-O-(4,4’-dimethoxytrityl oxy)morpholinocytosine | ||
novelN4-Benzoyl-7'-O-(4,4'-dimethoxytrityl oxy)morpholinocytosine is a Nucleoside Derivative - Morpholino nucleoside. | |||
TNU1659 | N4-Benzoyl-N-DMTr- morpholino-5-methylcytosine-5’-O-phosphoramidite | ||
N4-Benzoyl-N-DMTr- morpholino-5-methylcytosine-5’-O-phosphoramidite is a useful organic compound for research related to life sciences and the catalog number is TNU1659. | |||
T30117 | Ara-fluorocytosine | NSC529180,NSC 529180,NSC-529180 | |
Ara-fluorocytosine is a biochemical. | |||
TNU1628 | 1-[3’-O-[(4,4’-dimethoxytriphenyl)methyl]-a-L-threofuranosyl]-N4-benzoylcytosine | ||
1-[3’-O-[(4,4’-dimethoxytriphenyl)methyl]-a-L-threofuranosyl]-N4-benzoylcytosine is a useful organic compound for research related to life sciences. The catalog number is TNU1628 and the CAS number is 325683-91-8. | |||
T29453 | 5-Formylcytosine | ||
5-formylcytosine (5FC) is a rare base found in mammalian DNA. It participates in active DNA demethylation, changes DNA double helix structure, and reduces the transcription rate and substrate specificity of RNA polymeras... | |||
TNU0629 | 5-Iodocytosine | ||
5-Iodocytosine is a Heterocyclic compound-pyrimidine, intermediate and building block, halo-. | |||
TNU0642 | N4-Benzoyl-7’-OH-N-trityl morpholinocytosine | ||
N4-Benzoyl-7'-OH-N-trityl morpholinocytosine is a Morpholino-nucleoside. | |||
T34399 | Rovatirelin | KPS-0373,S0373,S-0373,S 0373 | AChE |
Rovatirelin (S-0373) is a newly synthesized thyrotropin-releasing hormone (TRH) analog that ameliorates cytosine arabinoside-induced motor dysfunction in a rat model of spinal cerebellar degeneration via acetylcholine an... | |||
T14578 | Biotin Hydrazide | Others | |
Biotin Hydrazide is a carbonyl-reactive biotinylation reagent, which is a carbonyl probe. Biotin Hydrazide is a great choice for labeling mouse monoclonal antibodies, lectins, sugars, unpaired cytosine residues in nuclei... | |||
T0251 | Gemcitabine | NSC 613327,LY188011 | Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Autophagy |
Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor and antimetabolic activities. Gemcitabine induces autophagy and apoptosis. | |||
TNU0425 | 2’-Deoxy-2’-fluoro-β-D-arabinocytidine hydrochloride | DNA Methyltransferase | |
2’-Deoxy-2’-fluoro-β-D-arabinocytidine hydrochloride is a cytosine nucleoside analog with inhibitory effects on DNA methyltransferase , with potential antimetabolic and antitumor activity. | |||
T6069 | Gemcitabine hydrochloride | Gemcitabine HCl,Gemzar,LY188011,LY 188011 hydrochloride | Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Autophagy |
Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor and antimetabolic activities. Gemcitabine induces autophagy a... | |||
T25286 | DANP | ||
DANP is a bulge base recognition probe. It is a potent and specific ligand of the single cytosine and thymine bulges with exclusively 1:1 stoichiometry. | |||
T40560 | Benzyl selenocyanate | ||
Benzyl selenocyanate is a chemopreventive agent that effectively inhibits chemically induced tumors at both initiation and postinitiation stages in animal models. It acts as a potent inhibitor of DNA (cytosine-5)-methylt... | |||
T68207 | Elsamitrucin | ||
Elsamitrucin is a heterocyclic antineoplastic antibiotic isolated from the bacterium Actinomycete strain J907-21. Elsamitrucin intercalates into DNA at guanine-cytosine (G-C)-rich sequences and inhibits topoisomerase I a... | |||
T40345 | AV-153 | ||
AV-153 is a 1,4-dihydropyridine derivative with antimutagenic properties. It intercalates into DNA at single strand breaks, resulting in reduced DNA damage and stimulation of DNA repair in human cells in vitro. AV-153 al... | |||
T37031 | Quinacrine mustard hydrochloride | Quinacrine mustard HCl | Autophagy |
Quinacrine mustard hydrochloride is a fluorescent dye and polycyclic aromatic agent that acts as a mutagen to induce mutants in bacteria.Quinacrine mustard hydrochloride selectively binds to adenine-thymine (AT) base pai... | |||
T61012 | Bobcat339 hydrochloride | ||
Bobcat339 hydrochloride can be used in the field of epigenetics and as a starting point for new therapeutics targeting DNA methylation and gene transcription. Bobcat339 hydrochloride is a potent and selective cytosine-ba... | |||
T60649 | AV-153 free base | ||
AV-153 free base is a 1,4-dihydropyridine (1,4-DHP) derivative. AV-153 free base is an antimutagenic with anti-cancer activity. AV-153 free base interacts with cytosine and thymine and has an influence on poly(ADP)ribosy... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T4832 | Cytosine | 6-Aminopyrimidin-2(1H)-one,4-Amino-2-hydroxypyrimidine,Cytosinimine | Endogenous Metabolite |
Cytosine (6-Aminopyrimidin-2(1H)-one) is a pyrimidine base that is a fundamental unit of nucleic acids. The deamination of cytosine alone is apparent and the nucleotide of cytosine is the prime mutagenic nucleotide in le... | |||
T1272 | Cytarabine | Ara-C,Cytosine Arabinoside,Cytosine β-D-arabinofuranoside,Arabinocytidine | Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite , Autophagy , HSV |
Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM). Cytarabine inhibits DNA polymerase and induces cell cycle arrest, autophagy, and apoptosis. Cytarabine has antitumor activity. | |||
T1591L | Cytidine | Cytosine-1-β-D-ribofuranoside,Cytosine β-D-riboside | Nucleoside Antimetabolite/Analog , Endogenous Metabolite |
Cytidine (Cytosine-1-β-D-ribofuranoside) is a pyrimidine nucleoside comprised of a cytosine bound to ribose via a beta-N1-glycosidic bond. Cytidine is a precursor for uridine. Both cytidine and uridine are utilized in RN... | |||
T4758 | 2'-Deoxycytidine | Cytosine deoxyribonucleoside,2'-Deoxycytidine monohydrate,2(1H)-Pyrimidinone,Cytosine deoxyriboside,Deoxyribose cytidine,Deoxycytidine | Endogenous Metabolite |
2'-Deoxycytidine (Deoxyribose cytidine) is one of the principal nucleosides of DNA composed of cytosine and deoxyribose. A nucleoside consists of only a pentose sugar linked to a purine or pyrimidine base, without a phos... | |||
T7520 | Deoxycytidine triphosphate | Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite | |
Deoxycytidine triphosphate is a nucleoside triphosphate.It is a raw material in DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing. | |||
T0986 | Flucytosine | 5-Fluorocytosine,Ro 2-9915,Fluorocytosine,NSC 103805 | DNA/RNA Synthesis , Antibiotic , Antifungal |
Flucytosine (NSC 103805) is a pyrimidine compound and a fluorinated cytosine analog exhibiting antifungal activity. | |||
T5270 | 5-Methylcytosine | Others , DNA/RNA Synthesis , Endogenous Metabolite | |
5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA. In animals, the DNA methylation of cytosine to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In plants, the methylated... | |||
T64878 | 2-O-Methylcytosine | ||
2-O-Methylcytosine is a natural product for research related to life sciences. The catalog number is T64878 and the CAS number is 3289-47-2. | |||
T4809 | Pyrimidine | Metadiazine | Others , Endogenous Metabolite |
Pyrimidine (Metadiazine)s are heterocyclic, six-membered, nitrogen-containing carbon ring structures, with uracil, cytosine and thymine being the basal structures of ribose-containing nucleosides (uridine, cytidine, and ... | |||
TMO2752 | Cytidine 5'-monophosphate | 5'-Cytidylic acid,5'-CMP,Cytidylic Acid | Others , Endogenous Metabolite |
Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide, one of the basic units that make up RNA. It consists of nucleobase cytosine, pentose ribose and phosphate groups. |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPH-00607 | Cytosine deaminase Protein, E. coli, Recombinant (His & SUMO) | E. coli | E. coli |
Catalyzes the hydrolytic deamination of cytosine to uracil. Is involved in the pyrimidine salvage pathway, which allows the cell to utilize cytosine for pyrimidine nucleotide synthesis. Is also able to catalyze deaminati... | |||
TMPH-02908 | AICDA Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation (SHM), gene conversion, and class-switch recombination (CSR) in B-lymphocytes by deaminating C to U during transcription of Ig-variable (... | |||
TMPH-01677 | MBD2 Protein, Human, Recombinant (His & KSI) | Human | E. coli |
Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcrip... | |||
TMPY-01306 | DNMT2 Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
DNMT2, also known as tRNA (cytosine-5-)-methyltransferase, DNA methyltransferase homolog HsaIIP, and TRDMT1, is a member of the DNA methyltransferase family of enzymes. DNMT2 enzymes have been widely conserved during evo... | |||
TMPH-01235 | APOBEC3A Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus... | |||
TMPH-02112 | SMUG1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The act... | |||
TMPH-01801 | NME2 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Negativ... | |||
TMPY-01285 | METTL11A Protein, Human, Recombinant | Human | E. coli |
Methyltransferase-like protein 11A, also known as METTL11A, is a member of the methyltransferase superfamily and METTL11 family. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a don... | |||
TMPY-01284 | METTL11A Protein, Human, Recombinant (GST) | Human | E. coli |
Methyltransferase-like protein 11A, also known as METTL11A, is a member of the methyltransferase superfamily and METTL11 family. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a don... | |||
TMPY-02000 | UNG Protein, Human, Recombinant (GST) | Human | E. coli |
Isoform 1 is widely expressed with the highest expression in skeletal muscle, heart and testicles. Isoform 2 has the highest expression levels in tissues containing proliferating cells. Uracil-DNA glycosylase exists in t... |
カタログ番号 | 製品名 | ||
---|---|---|---|
L3510 | Methylation Compound Library | 128 compounds | |
128 methylation-related compounds that can be used for high-throughput and high-content screening. |