Ilex | TargetMol

カタログ番号	製品名	別名	ターゲット
T2400	Candesartan Cilexetil	TCV-116	Apoptosis , RAAS
	Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist (IC50: 0.26 nM). After hydrolysis of candesartan cilexetil to candesartan during gastrointestinal absorption, candesartan selectively competes with...		Apoptosis , RAAS
T21591	1H-1-ethyl Candesartan Cilexetil		Others
	1H-1-ethyl Candesartan Cilexetil is a process-related impurity in the bulk synthesis of candesartan cilexetil, which is a potent, long-acting and selective angiotensin II type 1 receptor (AT1) antagonist.		Others
T25174	Brassilexin	Brassilexine
	Brassilexin is a cyclobrassinin hydrolase inhibitor, a unique enzyme from the fungal pathogen Alternaria brassicicola.
T124123	Ilexside I
	Ilexside I is a useful organic compound for research related to life sciences and the catalog number is T124123.
T35705	20-hydroxy Arachidic Acid
	20-hydroxy Arachidic acid is a hydroxylated fatty acid that has been found in the suberin component of silver birch (B. pendula) outer bark as well as the leaves, roots, and wood of Q. ilex from Cala Violina and Colognol...
T36174	Methyl 3,4-Dihydroxyphenylacetate
	Methyl 3,4-dihydroxyphenylacetate is a polyphenol that has been found inI. aquifoliumseeds and has antioxidant and antiviral activities.1,2It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50= 0...

Compounds

Candesartan Cilexetil

T2400

Synonym: TCV-116

Target: Apoptosis, RAAS

1H-1-ethyl Candesartan Cilexetil

Synonym: Brassilexine

20-hydroxy Arachidic Acid

T35705

Synonym:

Target:

Methyl 3,4-Dihydroxyphenylacetate

T36174

Synonym:

Target:

カタログ番号	製品名	別名	ターゲット
T2S0501	Ilexgenin A		IL Receptor , TNF
	Ilexgenin A is a novel pentacyclic triterpenoid, is a compound extracted from leaves of Ilex hainanensis Merr		IL Receptor , TNF
T2S0504	Ilexoside D		Others
	Ilexoside D has ant-allergic, and anti-coagulant activities, it shows anti-tissue factor activity as well as the antithrombotic activity.		Others
T2S0500	Ilexsaponin A	Ilexsaponin A1	Others
	1. Ilexsaponin A (Ilexsaponin A1) shows protective effects on ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway.		Others
TJS0502	Ilexsaponin B2
	Ilexsaponin B2 is a natural product for research related to life sciences. The catalog number is TJS0502 and the CAS number is 108906-69-0.
TN1474	Caulilexin C		Others , Antifungal
	Caulilexin C shows inhibitory activity on human Acyl CoA: cholesterol transferase I (hACATI) and on human Acyl CoA: cholesterol transferase 2 (hACAT2) at 100 mug/ml.		Others , Antifungal
TN1763	Ilexsaponin B3	Ilexoside K	Others
	Ilexoside K is a natural product from Ilex pubescens.		Others
TN2421	Ilexgenin B		Others
	Ilexgenin B is a natural product from Ilex chinensis Sims		Others
T38777	Ilexoside O
	Ilexoside O, a triterpene saponin derived from Ilex pubescens roots, demonstrates modest inhibition of xanthine oxidase (XOD) activity with an IC50 value of 53.05 μM.
T75696	Ilexoside XLVIII
	Ilexoside XLVIII, a triterpene saponin isolated from the aqueous extract of Ilex kudincha leaves [1], functions as an acyl CoA cholesteryl acyl transferase (ACAT) inhibitor.
TN1762	Ilexhainanoside D		Others
	Ilexhainanoside D is a natural product from Periploca sepiumBge.		Others
T2824	Pedunculoside		Others , Fatty Acid Synthase
	Pedunculoside is extracted from Ilex rotunda Thunb.		Others , Fatty Acid Synthase
T3S0208	Hederagenin 28-O-beta-D-glucopyranosyl ester	Hederagenin-28-beta-D-glucopyranoside	Others
	Hederagenin-28-beta-D-glucopyranoside, a triterpene saponin isolated from Ilex cornuta, protects cardiac myocytes against H2O2-induced damage.		Others
TN1836	Kudinoside D		LDL , AMPK , PPAR
	Kudinoside D exerts anti-adipogenic effects through modulation of adipogenic transcription factors via AMPK signaling pathway.		LDL , AMPK , PPAR
TN4081	Fraxiresinol 1-O-glucoside		Others
	Fraxiresinol 1-O-glucoside is a natural product from Ilex pubescens.		Others
TN5962	Rotundanonic acid
	Rotundanonic acid is a natural product from Ilex Rotunda.
T39107	5-O-(3'-O-Glucosylcaffeoyl)quinic acid
	5-O-(3'-O-Glucosylcaffeoyl)quinic acid (compound 19) is a phenolic compound primarily located in the leaves of Ilex glabra L. Gray (Aquifoliaceae).
TN2985	30-Oxolupeol		Others
	30-Oxolupeol is a natural product of Ilex, Aquifoliaceae. The catalog number is TN2985 and the CAS number is 64181-07-3. 30-Oxolupeol can be used as a reference standard.		Others
TN4943	Sanguisorbigenin	Tomentosolic acid,3β-Hydroxyurs-12,19-dien-28-oic acid,19-Dehydroursolic acid,Ursa-12,19-dien-28-oic acid	Antibacterial
	Sanguisorbigenin (Tomentosolic acid) is a natural antimicrobial agent that inhibits methicillin-resistant Staphylococcus aureus (MRSA).		Antibacterial
T3S0507	Homovanillic acid	Homovaniuic acid,Vanilacetic acid,Vanillacetic acid	Others , Endogenous Metabolite
	Homovanillic acid (Vanillacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, growth hormone deficiency, celiac disease, and sepiapterin reductase deficiency.		Others , Endogenous Metabolite
T3819	Ursolic acid acetate	Acetylursolic acid,3-Acetylursolic Acid	AChE
	Ursolic acid acetate (Acetylursolic acid) has cytotoxic activity, antimalarial activity, antitumor and anticancer activities. Acetylursolic acid has NO production inhibitory activities. Acetylursolic acid has inhibition ...		AChE
T5S0506	Rotundic acid	Rutundic acid	Apoptosis , Others , p38 MAPK , Akt , mTOR
	Rotundic acid (Rutundic acid), a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), and colon cancer (HT-29) c...		Apoptosis , Others , p38 MAPK , Akt , mTOR