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天然化合物

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カタログ番号	製品名	別名	ターゲット
T8221	Insulin (human)	INSULIN,Insulin(human)	IGF-1R
	Insulin (human) is a peptide hormone that promotes glycogen synthesis and regulates glucose levels in the blood. Insulin (human) has hypoglycemic activity and is used clinically to treat hyperglycemia in diabetic patient...		IGF-1R
T6793	BRD7552		Others
	BRD7552 is an inducer of transcription factor PDX1, which increases insulin expression. BRD7552 increases PDX1 expression in mouse αTC cells but not βTC cells.		Others
T9266	Fatostatin		Lipid , Fatty Acid Synthase
	Fatostatin is a specific inhibitor of SREBP activation, it impairs the activation of SREBP-1 and SREBP-2. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs.		Lipid , Fatty Acid Synthase
T8233	BRD3308		Apoptosis , HIV Protease , HDAC
	BRD3308 is a highly selective inhibitor of HDAC3(IC50 of 54 nM), attenuating PE-mediated phosphorylation of ERK but not JNK.		Apoptosis , HIV Protease , HDAC
T7714	Temocapil		Tyrosinase
	Temocapril is an inhibitor of tyrosine kinase.		Tyrosinase
T6832	Fatostatin hydrobromide	Fatostatin HBr,Fatostatin A,Fatostatin A HBr,Fatostatin	NPC1L1 , Fatty Acid Synthase
	Fatostatin hydrobromide (Fatostatin A HBr) ia an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2.		NPC1L1 , Fatty Acid Synthase
T6698	Temocapril hydrochloride	CS-622 HCl,Acecol,Temocapril HCl,CS-622	RAAS
	Temocapril hydrochloride (CS-622 HCl), the hydrochloride of Temocapril, is a long-acting ACE inhibitor used for the therapy of hypertension.		RAAS
T21761	HNMPA		IGF-1R
	HNMPA is a membrane impermeable inhibitor of insulin receptor tyrosine kinase. HNMPA inhibits tyrosine and serine autophosphorylation by the human insulin receptor. HNMPA exhibits no effect on cyclic AMP-dependent prote...		IGF-1R
T76664	Adropin (34-76) (human, mouse, rat)
	Adropin (34-76) (human, mouse, rat) is a peptide that attenuates liver fibrosis and insulin resistance independent of obesity or food intake.
TP1863L	Glucagon (19-29), human acetate		Glucagon Receptor
	Glucagon (19-29), human acetate a COOH-terminal fragment processed from glucagon, is a potent and efficient inhibitor of insulin secretion.		Glucagon Receptor
TP2018L	GIP (human) acetate	GIP (human) acetate(100040-31-1 Free base)	IGF-1R
	GIP (human) acetate is a stimulator of glucose-dependent insulin secretion and a weak inhibitor of gastric acid secretion. GIP (human) acetate plays a vital role in lipid metabolism and the development of obesity.		IGF-1R
T62656	GPR81 agonist 1		GPR
	GPR81 agonist 1 is a potent and selective GPR81 agonist with high affinity for human and mouse GPR81.GPR81 agonist 1 inhibits lipolysis of differentiated 3T3-L1 adipocytes, improves insulin sensitivity and glycaemic cont...		GPR
T72947	JBSNF-000028	JBSNF-000028 free base	Others
	JBSNF-000028 is an orally active and potent nicotinamide N-methyltransferase (NNMT) inhibitor with inhibitory effects on human NNMT (hNNMT), monkey NNMT (mkNNMT), and mouse NNMT (mNNMT) with IC50s of 0.033 μM, 0.19 μM, a...		Others
TP2312	MOTS-c(Human) Acetate（1627580-64-6 free）		Others , AMPK
	MOTS-c(Human) Acetate is a mitochondrial-derived peptide. MOTS-c(human) acetate induces the accumulation of AMP analog AICAR, increases activation of AMPK and expression of its downstream GLUT4. MOTS-c(human) acetate ind...		Others , AMPK
T15810	LY2922470		GPR
	LY2922470 reduces glucose levels along with significant enhancements in insulin and GLP-1, which is the potential for the treatment of type 2 diabetes mellitus (T2DM). LY2922470 is an effective, selective, and orally ava...		GPR
T12853	SBI-477		Others
	SBI-477 is a chemical probe stimulated insulin signaling by deactivating the transcription factor MondoA. SBI-477 coordinately inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal...		Others
T68405	KW-2450 free base		IGF-1R
	KW-2450 free base is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity. IGF-1R/IR inhibitor KW-2450 free ...		IGF-1R
T6017	Linsitinib	OSI-906	IGF-1R
	OSI-906 (Linsitinib (OSI-906)) is an orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. Linsitinib selectively inhibits IGF-1R, whic...		IGF-1R
TP1664	Proinsulin C-Peptide (55-89), human
	Human proinsulin, the single-chain peptide precursor of insulin, consists of the insulin A and B chains connected by the 31 amino acid C-peptide. Cleavage of proinsulin by proteolytic enzymes produces insulin and free C-...
TP1584	GIP (1-30) amide,human	GIP (1-30) amide (Human)
	GIP (1-30) amide (Human) is an insulin-dependent glucose-dependent polypeptide.The sugar-dependent insulin polypeptide (GIP) is an insulin secreting hormone, which can stimulate the secretion of insulin and reduce the oc...
T80149	GRPP (human)
	GRPP (human), a 30-amino-acid peptide derived from Gcg, modestly elevates plasma insulin levels while reducing plasma glucagon concentrations. However, GRPP (human) has no impact on insulin secretion within rat islets [1...
T30261	AZD6482 (S-isomer)	AZD-6482,AZD 6482,AZD6482 (S),AZD6482
	AZD6482 (S-isomer) is a potent, selective, ATP-competitive PI3Kβ inhibitor (IC(50) 0.01 μm), which can inhibit insulin-induced in vitro glucose uptake by human adipocytes (IC(50) is 4.4 μm).
TP1361	S961 TFA (1083433-49-1 free base)	S961 TFA
	S961 TFA is A high affinity insulin receptor (IR) antagonist with IC50 for hir-a, hir-b and human insulin-like growth factor I receptor (higf-ir) at 0.048, 0.027 and 630 nM, respectively.
TP1621	Insulin alpha-chain (1-13)	Insulin alpha-chain 1-13
	This peptide is a fragment of the alpha-chain of insulin amino acids 1 to 13. The insulin a-chain epitope recognized by human T cells is posttranslationally modified.
T73706	Insulin glulisine
	Insulin glulisine (HMR 1964) is a rapid-acting analog that closely resembles the pharmacokinetic and pharmacodynamic characteristics of physiological human insulin. It is applicable in diabetes research [1].
T76043	S961 TFA
	S961 TFA is a highly selective and high-affinity antagonist of the insulin receptor (IR), demonstrating IC50 values of 0.048 nM for HIR-A, 0.027 nM for HIR-B, and 630 nM for the human insulin-like growth factor I recepto...
T71020	PF-04671536
	PF-04671536 is a highly potent and selective inhibitor of phosphodiesterase 8B (PDE8B) phosphodiesterase 8A (PDE8A). In primary human pancreatic islets, PF-04671536 increases insulin secretion in a glucose-dependent mann...
T38764	Amylin (8-37), human
	Amylin (8-37), human, derived from human Amylin, possesses direct vasodilator effects in isolated mesenteric resistance arteries of rats. Human Amylin is a small pancreatic β-cell hormone that forms aggregates in the abs...
T80605	Dusigitumab	MEDI 573	IGF-1R
	Dusigitumab (MEDI 573) is a human IgG2λ monoclonal antibody targeting the insulin-like growth factors IGF2 and IGF1, offering therapeutic potential for conditions related to these proteins [1].		IGF-1R
TP1566	GIP (1-30) amide (Human) (TFA)
	GIP (1-30) amide (Human) TFA is a glucose-dependent insulinotropic polypeptide fragment. Glucose-dependent insulinotropic polypeptide (GIP) is an incretin hormone that stimulates insulin secretion and reduces postprandia...
T81554	Pancreastatin (37-52), human
	Pancreastatin (37-52), human, is a biologically active fragment of CgA-derived peptide (residues 250–301) that inhibits insulin release from islet beta cells [1][2].
T76041	GIP (1-30) amide,human acetate
	GIP (1-30) amide, human acetate is a fragment of glucose-dependent insulinotropic polypeptide (GIP), an incretin hormone that plays a crucial role in stimulating insulin secretion and mitigating postprandial glycemic exc...
T76043L	S961 acetate
	S961 acetate is a selective and high-affinity antagonist of the insulin receptor (IR), demonstrating IC50 values of 0.048 nM for HIR-A, 0.027 nM for HIR-B, and 630 nM for the human insulin-like growth factor I receptor (...
T77037	Insulin efsitora alfa
	Insulin efsitora alfa (LY-3209590) is a selective insulin receptor (IR) agonist, comprising a fusion protein that integrates human IR agonists with the crystallizable (Fc) domain of human immunoglobulin G2 (IgG2), and ha...
T35588	Ganglioside GM3 Mixture (sodium salt)
	Ganglioside GM3 is a monosialoganglioside that demonstrates antiproliferative and proapoptotic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation. It suppresses angiogenesis and reduce...
T37589L	GIP (3-42), human acetate	GIP (3-42), human acetate(1802086-25-4 Free base)	IGF-1R
	GIP (3-42), human acetate is an antagonist of a glucose-dependent insulinotropic polypeptide (GIP) receptor and regulates insulin secretion and GIP metabolism in vivo.		IGF-1R
TP1795	S961
	S961 is an high-affinity and selective insulin receptor (IR) antagonist with IC50s of 0.048,0.027, and 630 nM for HIR-A, HIR-B, and human insulin-like growth factor I receptor (HIGF-IR) in scintillation proximity assay, ...
TP1954	PHM-27 (human)
	Endogenous peptide product of human prepro-VIP and analog of porcine PHI-27; potent agonist for the human calcitonin receptor (EC50 = 11 nM). Transgenic mice expressing the human VIP/PHM 27 gene in pancreatic β-islets di...
T76539	Insulin-like growth factor II
	Insulin-like Growth Factor II (IGF-2), the primary somatomedin in human serum, exerts both permissive and direct influences on neurite outgrowth and significantly improves the survival of sympathetic and sensory neurons ...
T37799	PF 04671536 hydrochloride
	Potent and selective PDE8B/8A inhibitor ( IC50 values are 1.3 and 1.9 nM, respectively). Exhibits selectivity for PDE8A/B over other PDEs (IC50 values are >10 μM) and a range of other targets. Increases glucose-dependen...
T77790	Phenylarsine oxide	Oxophenylarsine
	Phenylarsine Oxide (Oxophenylarsine) is a membrane-permeable tyrosine phosphatase inhibitor with an IC50 value of 18 µM that stimulates 2-deoxyglucose transport in insulin-resistant human skeletal muscle.
T73702	Mecasermin
	Mecasermin (Human IGF-I; FK 780), a recombinant form of human insulin-like growth factor I (IGF-I), holds promise for investigating growth failure attributed to growth hormone (GH) insensitivity, which may be due to defe...
T15043	D5D-IN-326		Others
			Others
T76330	Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide
	Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide, a biotin-labeled variant of glucagon-like peptide-1-(7-36), is a gastrointestinal peptide recognized for its antidiabetogenic properties, including the ability to e...
T70876	KW-2450 Tosylate
	KW-2450 Tosylate is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity. IGF-1R/IR inhibitor KW-2450 Tosyla...
T61506	NBI-31772 hydrate
	NBI-31772 hydrate is a powerful inhibitor of the interaction between insulin-like growth factor (IGF) and IGF-binding proteins (IGFBPs). It acts as a nonpeptide ligand, effectively releasing bioactive IGF-I from the IGF-...
T37589	GIP (3-42), human	Gastric Inhibitory Polypeptide (3-42) (human)	IGF-1R
	GIP (3-42), human (Gastric Inhibitory Polypeptide (3-42) (human)) is a peptide that acts as a glucose-dependent proinsulinotropic polypeptide (GIP) receptor antagonist and regulates insulin secretion and the metabolic ef...		IGF-1R
T76964	Valanafusp alfa
	Valanafusp alfa (AGT-181) is a recombinant fusion protein that combines a chimeric monoclonal antibody targeting the human insulin receptor (HIR) with human iduronidase (IDUA), facilitating brain penetration. It is utili...
T76307	[Tyr0] Gastric Inhibitory Peptide (23-42), human
	[Tyr0] Gastric Inhibitory Peptide (23-42), human, functions as a glucose-dependent insulinotropic polypeptide (GIP) and exhibits dual activity: it modestly inhibits gastric acid secretion while simultaneously enhancing i...
T76759	Robatumumab
	Robatumumab (Sch 717454), an anti-human insulin-like growth factor receptor-1 (IGF-1R) antibody, exhibits anti-tumor and anti-proliferative effects on cancer cells. It is applicable in research concerning osteosarcoma an...

Compounds

Insulin (human)

T8221

Synonym: INSULIN,Insulin(human)

Target: Lipid, Fatty Acid Synthase

BRD3308

T8233

Synonym:

Target: Apoptosis, HIV Protease, HDAC

Fatostatin hydrobromide

T6832

Synonym: Fatostatin HBr,Fatostatin A,Fatostatin A HBr,Fatostatin

Target: NPC1L1, Fatty Acid Synthase

Temocapril hydrochloride

T6698

Synonym: CS-622 HCl,Acecol,Temocapril HCl,CS-622

Adropin (34-76) (human, mouse, rat)

T76664

Synonym:

Target:

Glucagon (19-29), human acetate

TP1863L

Synonym:

Target: Glucagon Receptor

GIP (human) acetate

TP2018L

Synonym: GIP (human) acetate(100040-31-1 Free base)

Synonym: JBSNF-000028 free base

Target: Others

MOTS-c(Human) Acetate（1627580-64-6 free）

Proinsulin C-Peptide (55-89), human

TP1664

Synonym:

Target:

GIP (1-30) amide,human

TP1584

Synonym: GIP (1-30) amide (Human)

Synonym: AZD-6482,AZD 6482,AZD6482 (S),AZD6482

Target:

S961 TFA (1083433-49-1 free base)

TP1361

Synonym: S961 TFA

Target:

Insulin alpha-chain (1-13)

TP1621

Synonym: Insulin alpha-chain 1-13

Amylin (8-37), human

GIP (1-30) amide (Human) (TFA)

TP1566

Synonym:

Target:

Pancreastatin (37-52), human

T81554

Synonym:

Target:

GIP (1-30) amide,human acetate

Insulin efsitora alfa

T77037

Synonym:

Target:

Ganglioside GM3 Mixture (sodium salt)

T35588

Synonym:

Target:

GIP (3-42), human acetate

T37589L

Synonym: GIP (3-42), human acetate(1802086-25-4 Free base)

Insulin-like growth factor II

T76539

Synonym:

Target:

PF 04671536 hydrochloride

Synonym: Oxophenylarsine

Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide

Synonym: Gastric Inhibitory Polypeptide (3-42) (human)

[Tyr0] Gastric Inhibitory Peptide (23-42), human

カタログ番号	製品名	別名	ターゲット
T3S0027	Picropodophyllotoxin	AXL 1717,Picropodophyllin	IGF-1R
	Picropodophyllotoxin (AXL 1717) is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum), and a small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF1R) with potential anti...		IGF-1R

天然物製品

Picropodophyllotoxin

T3S0027

Synonym: AXL 1717,Picropodophyllin

Target: IGF-1R

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-00395	Insulin Protein, Human, Recombinant	Human	P. pastoris (Yeast)
	INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsul...
TMPY-01146	Insulin Receptor Protein, Human, Recombinant (long isoform, His)	Human	HEK293 Cells
	Insulin Receptor Protein, Human, Recombinant (long isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1.
TMPY-04395	Insulin Receptor Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Insulin Receptor Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 72.3 kDa and the accession number is P06213-1.
TMPY-01149	Insulin Receptor Protein, Human, Recombinant (short isoform, His)	Human	HEK293 Cells
	Insulin Receptor Protein, Human, Recombinant (short isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 106 kDa and the accession number is P06213-2.
TMPY-05283	Insulin Receptor Protein, Human, Recombinant (long isoform, His), Biotinylated	Human	HEK293 Cells
	Insulin Receptor Protein, Human, Recombinant (long isoform, His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1.
TMPY-00545	Dermcidin Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Hepatocellular carcinoma (HCC) is a major contributor to cancer-related deaths due to its often late stage diagnosis, and dermcidin (DCD) may have the potential to be used as a serum biomarker for HCC for more timely dia...
TMPY-00566	CCL18 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its...
TMPH-01094	CELA2A Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and i...
TMPH-01093	CELA2A Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and i...
TMPH-02323	SLC30A8 Protein, Human, Recombinant (His)	Human	E. coli
	Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-...
TMPK-00751	FSTL3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Follistatin-like 3 (FSTL3) is a novel cytokine that regulates insulin sensitivity and counteracts activin/myostatin signalling. In the present study, regulation of FSTL3 in renal dysfunction was investigated in both huma...
TMPH-01562	IAPP Protein, Human, Recombinant (GST)	Human	E. coli
	Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. IAPP Protein, Human, Recombinant (GST) is expressed in E. coli expression s...
TMPY-06479	Cathepsin H Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Proinflammatory cytokines decreased the expression of CTSH in human islets and primary rat beta-cells, and overexpression of CTSH protected insulin-secreting cells against cytokine-induced apoptosis. Cathepsin H Protein,...
TMPH-02197	TXNDC5 Protein, Human, Recombinant	Human	E. coli
	Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast. TXNDC5 Protein, Human, Recombinant is expressed in E. coli expression sy...
TMPH-02196	TXNDC5 Protein, Human, Recombinant (GST)	Human	E. coli
	Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast. TXNDC5 Protein, Human, Recombinant (GST) is expressed in E. coli express...
TMPK-00863	LTK Potein, Human, Recombinant (His)	Human	HEK293 Cells
	Leukocyte tyrosine kinase (LTK) is a receptor tyrosine kinase that belongs to the insulin receptor family. LTK is mainly expressed in pre B cells and brain. LTK Potein, Human, Recombinant (His) is expressed in HEK293 mam...
TMPY-04081	Cathepsin H Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Proinflammatory cytokines decreased the expression of CTSH in human islets and primary rat beta-cells, and overexpression of CTSH protected insulin-secreting cells against cytokine-induced apoptosis. Cathepsin H Protein,...
TMPY-05014	INSL6 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	INSL6 (Insulin-Like 6) is a Protein Coding gene. An important paralog of this gene is RLN1. The protein encoded by this gene contains a classical signature of the insulin superfamily and is significantly similar to relax...
TMPK-01361	IGF2R Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Pro...
TMPJ-01166	IGFBP-7 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Insulin-like growth factor-binding protein 7(IGFBP-7) is a secreted glycosylated protein that contains three protein domain modules. IGFBP7 contains an N-terminal IGFBP domain, followed by a Kazal-type serine proteinase ...
TMPK-01354	IGF2R Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Pro...
TMPY-05029	INHBE Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	INHBE (Inhibin Subunit Beta E) is a Protein Coding gene. This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to gen...
TMPH-01385	GLP1R Protein, Human, Recombinant (His)	Human	HEK293 Cells
	G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a ...
TMPJ-00781	LR3-IGF-1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mouse IGF-I is synthesized as two precursor isoforms with alternate N- and C-termin...
TMPH-02022	RXFP2 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3). RXFP2 Pro...
TMPK-01355	IGF2R Domain 1-7 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Dom...
TMPK-01353	IGF2R Domain 1-3 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Dom...
TMPY-04387	AKT2 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	AKT (AK mouse plus Transforming or Thymoma) is a frequent oncogene expressed in most tissues which includes three isoforms AKT1, AKT2, and AKT3. Hyperactivation of AKT signaling is a central key in many human cancer prog...
TMPH-01384	GLP1R Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a ...
TMPH-01540	Intelectin-1/ITLN1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner. Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-G...
TMPY-02519	BLVRB Protein, Human, Recombinant (His)	Human	E. coli
	Biliverdin reductase (hBVR) is a serine/threonine kinase that catalyzes reduction of the heme oxygenase (HO) activity product, biliverdin, to bilirubin. BVR consists of an N-terminal dinucleotide-binding domain (Rossmann...
TMPH-01462	HNRNPH1 Protein, Human, Recombinant (GST)	Human	E. coli
	This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in ...
TMPY-01960	Munc18c/STXBP3 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Syntaxin-binding protein 3, also known as Platelet Sec1 protein, Protein unc-18 homolog 3, Protein unc-18 homolog C, Unc-18C, Unc18-3 and STXBP3, is a cytoplasm protein which belongs to the STXBP/unc-18/SEC1 family. STXB...
TMPJ-00014	Resistin Protein, Human, Recombinant (His)	Human	E. coli
	Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seems to suppress insulin ability to stimulate glucose uptake into ...
TMPJ-01082	IGFBP-5 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Mouse Insulin-like growth factor-binding protein 5(IGFBP-5) belongs to the superfamily of insulin-like growth factor (IGF) binding proteins. It contains 1 IGFBP N-terminal domain and 1 thyroglobulin type-1 domain. Mouse ...
TMPY-03962	AFM Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Afamin is an 87 kDa glycoprotein with five predicted N-glycosylation sites. Afamin's glycan abundance contributes to conformational and chemical inhomogeneity presenting great challenges for molecular structure determina...
TMPJ-00286	ANGPTL3 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Angiopoietin-like 3 (ANGPTL3) is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain. ANGPTL3 ...
TMPY-00150	IGF2/IGF-II Protein, Human, Recombinant	Human	P. pastoris (Yeast)
	Insulin-like growth factor 2 (IGF-2/IGF-II) is a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele,...
TMPY-02135	S100A16 Protein, Human, Recombinant	Human	E. coli
	S100A16 is a member of S100 protein superfamily that carries calcium-binding EF-hand motifs. S100 proteins are cell- and tissue-specific and are involved in many intra- and extracellular processes through interacting wit...
TMPY-04813	ACAT2 Protein, Rat, Recombinant (His)	Rat	E. coli
	Acyl-coenzyme A: cholesterol acyltransferase (ACAT) is an intracellular enzyme that produces cholesteryl esters in various tissues. In mammals, two ACAT genes (ACAT1 and ACAT2) have been identified. Together, these two e...
TMPJ-01177	NOV/CCN3 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	NOV, also called CCN3, is a secreted protein of CCN family members. CCN family members are highly conserved cysteine rich proteins sharing a common modular structure having 4 conserved domains, insulin-like growth factor...
TMPK-01534	Chimeric HLA-A02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human*&Mouse, MHC (His & Avi)	Human & Mouse	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel...
TMPK-01535	Chimeric HLA-A02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human*&Mouse, MHC (His & Avi)	Human & Mouse	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel...
TMPK-01522	Chimeric HLA-A02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human*&Mouse, MHC (His & Avi)	Human & Mouse	HEK293 Cells
	The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en...
TMPK-01523	Chimeric HLA-A02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human*&Mouse, MHC (His & Avi)	Human & Mouse	HEK293 Cells
	The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en...