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カタログ番号 | 製品名 | 別名 | ターゲット |
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T79314 | PD-L1-IN-3 | PD-1/PD-L1 | |
PD-L1-IN-3 (Compound 4a) functions as an inhibitor targeting the PD-1/PD-L1 axis, with an IC50 value of 4.97nM for PD-L1 inhibition and an EC50 value of 2.70 μM for Jurkat T cell modulation. It antagonizes the PD-1/PD-L1... | |||
TP1463 | PD-1/PD-L1-IN 3 TFA (1629654-95-0 free base) | PD-1/PD-L1-IN 3 TFA | |
PD-1/PD-L1-IN 3 TFA inhibits the binding of human PD-1 to PD-Ll with an IC50 of 9 nM. | |||
T73642 | PD-1/PD-L1-IN 3 TFA | ||
PD-1/PD-L1-IN 3 TFA, a macrocyclic peptide, serves as a potent and selective inhibitor of PD-1/PD-L1 interaction. This compound disrupts PD-L1's binding with PD-1 and CD80 by directly binding to PD-L1, exhibiting IC50 va... | |||
T79740 | CYP51/PD-L1-IN-3 | ||
CYP51/PD-L1-IN-3 (compound L21), a quinazoline with antifungal properties, serves as a dual inhibitor targeting CYP51 (IC50: 0.205 μM) and PD-L1 (IC50: 0.039 μM). This compound promotes early fungal apoptosis within the ... | |||
T37535 | Camrelizumab | SHR-1210 | |
Camrelizumab (SHR-1210) is a human IgG4-κ monoclonal antibody with high affinity and directed against PD-1.Camrelizumab binds PD-1 with a binding affinity of up to 3 nM and is inhibitory to PD-1/PD-L1 with an IC50 of 0.7... | |||
T79634 | LYP-IN-3 | Phosphatase | |
LYP-IN-3 (compound D34) is a selective Lymphoid-tyrosine phosphatase (LYP) inhibitor (Ki=0.93 μM) that modulates the T-cell receptor (TCR) signaling pathway during tumor progression. It promotes T-cell activation, hinder... | |||
T72691 | PD-1/PD-L1-IN-28 | ||
PD-1/PD-L1-IN-28, an inhibitor of the PD-1/PD-L1 signaling pathway (IC 50 = 0.744 µM), demonstrates promising research potential in tumor immunity. This immune checkpoint inhibitor effectively blocks the interaction with... | |||
T36047 | LH1307 | ||
LH1307 is an inhibitor of the interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 that has an IC50 value of 3 nM in a homologous time-resolved fluorescence (HTRF) assay.1 It increases the activation o... | |||
T82414 | Favezelimab | MK-4280 | |
Favezelimab (MK-4280) is a humanized anti-LAG-3 monoclonal antibody that inhibits the LAG-3/MHC class II interaction and shows potential for use in colorectal cancer (CRC) research, particularly when combined with the PD... | |||
T76997 | Socazolimab | ||
Socazolimab (ZKAB001), an anti-PD-L1 monoclonal antibody, demonstrates enduring safety and efficacy in treating recurrent or metastatic cervical cancer. Additionally, it shows promise for treating small cell lung cancer,... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T6S0071 | Fraxinellone | HIF/HIF Prolyl-Hydroxylase , STAT , PD-1/PD-L1 | |
1. Fraxinellone significantly reduced weight loss and diarrhea in mice and alleviated the macroscopic and microscopic signs of the disease. 2. Fraxinellone exhibited a variety of insecticidal activities including feeding... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-00892 | Neuropilin-2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Neuropilin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 95 kDa and the accession number is O60462-3. | |||
TMPY-01897 | PRSS3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains on... | |||
TMPY-05191 | CD47 Protein, Human, Recombinant, Biotinylated | Human | HEK293 Cells |
CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3. | |||
TMPY-01020 | Periostin/OSF-2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Periostin/OSF-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is Q15063-3. | |||
TMPY-04683 | CD47 Protein, Human, Recombinant | Human | HEK293 Cells |
CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3. | |||
TMPY-03763 | Neuropilin-2 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Neuropilin-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 120.7 kDa and the accession number is O60462-3. | |||
TMPY-00357 | HNT/NTM Protein, Human, Recombinant (His) | Human | HEK293 Cells |
HNT/NTM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the accession number is Q9P121-3. | |||
TMPY-06986 | FGF-8b Protein, Human, Recombinant | Human | E. coli |
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment... | |||
TMPY-04142 | RANK/TNFRSF11A Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
RANK/TNFRSF11A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.8 kDa and the accession number is Q9Y6Q6-3. | |||
TMPY-00132 | Mesothelin Protein, Human, Recombinant | Human | HEK293 Cells |
Mesothelin Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 32.4 kDa and the accession number is Q13421-3. | |||
TMPY-05748 | CD45 Protein, Human, Recombinant (aa 26-577, His) | Human | HEK293 Cells |
CD45 Protein, Human, Recombinant (aa 26-577, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.2 kDa and the accession number is P08575-3. | |||
TMPY-04298 | CDCP1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CDCP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.4 kDa and the accession number is Q9H5V8-3. | |||
TMPY-04935 | CD47 Protein, Human, Recombinant (aa 1-139, His) | Human | HEK293 Cells |
CD47 Protein, Human, Recombinant (aa 1-139, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is Q08722-3. | |||
TMPY-01180 | CD86 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CD86 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P42081-3. | |||
TMPY-00480 | NCAM1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
NCAM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.1 kDa and the accession number is P13591-3. | |||
TMPY-00072 | GITR/TNFRSF18 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
GITR/TNFRSF18 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is Q9Y5U5-3. | |||
TMPJ-01099 | IL-15RA Protein, Human, Recombinant (hFc, Human Cells) | Human | HEK293 Cells |
Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bi... | |||
TMPY-05246 | CD86 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
CD86 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P42081-3. | |||
TMPY-03621 | EphB2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
EphB2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.6 kDa and the accession number is P54763-3. | |||
TMPY-00276 | PLGF/PGF Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
PLGF/PGF Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 43.7 kDa and the accession number is P49763-3. | |||
TMPY-05514 | RANK/TNFRSF11A Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
RANK/TNFRSF11A Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 46.5 kDa and the accession number is Q9Y6Q6-3. | |||
TMPY-03960 | COL9A1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
COL9A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.2 kDa and the accession number is P20849-3. | |||
TMPY-04386 | EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) | Human | Baculovirus Insect Cells |
EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.2 kDa and the accession number is P29323-3. | |||
TMPY-02691 | IL-17RC Protein, Human, Recombinant(aa 1-454, hFc) | Human | HEK293 Cells |
IL-17RC Protein, Human, Recombinant(aa 1-454, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 75.3 kDa and the accession number is Q8NAC3-3. | |||
TMPY-03435 | NCKIPSD Protein, Human, Recombinant (GST) | Human | E. coli |
NCKIPSD is localized exclusively in the cell nucleus. It plays a role in signal transduction and may function in the maintenance of sarcomeres and the assembly of myofibrils into sarcomeres. NCKIPSD also plays an importa... | |||
TMPJ-00054 | PLGF-2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Placental growth factor is a protein that in humans is encoded by the PGF gene. It is a secreted protein and belongs to the PDGF/VEGF growth factor family. Alternate splicing results in at least three human mature PlGF f... | |||
TMPJ-00391 | FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) | Human | HEK293 Cells |
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession number is P21802-3. | |||
TMPK-00398 | FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) | Human | HEK293 Cells |
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3. | |||
TMPJ-01288 | KLF6 Protein, Human, Recombinant | Human | E. coli |
Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by ... | |||
TMPY-03883 | CD47 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
CD47 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.7 kDa and the accession number is Q08722-3. | |||
TMPY-06411 | GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17.79 kDa and the accession number is Q9Y5U5-3. | |||
TMPY-01656 | VEGF183 Protein, Human, Recombinant | Human | Baculovirus Insect Cells |
VEGF183 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 21 kDa and the accession number is P15692-3. | |||
TMPY-05383 | NKp30/NCR3 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
NKp30/NCR3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.6 kDa and the accession number is O14931-3. | |||
TMPY-01268 | SMYD3 Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger... | |||
TMPY-04273 | FGFR2 Protein, Human, Recombinant (aa 1-378, His) | Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (aa 1-378, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 41.1 kDa and the accession number is P21802-3. | |||
TMPY-05590 | NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 67.9 kDa and the accession number is P13591-3. | |||
TMPY-04157 | RANK/TNFRSF11A Protein, Human, Recombinant (His) | Human | HEK293 Cells |
RANK/TNFRSF11A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.5 kDa and the accession number is Q9Y6Q6-3. | |||
TMPY-03969 | SUSD4 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
SUSD4, also known as sushi domain-containing protein 4, is a hypothetical cell surface protein whose tissue distribution and function are completely unknown. SUSD4 is detectable in murine brains, eyes, spinal cords, and ... | |||
TMPK-00399 | FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated | Human | HEK293 Cells |
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3. | |||
TMPJ-00899 | HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc) | Human | HEK293 Cells |
HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 65 KDa and the accession number is P21860-3. | |||
TMPK-00447 | CD45 Protein, Human, Recombinant (aa 26-577, hFc) | Human | HEK293 Cells |
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com... | |||
TMPJ-00390 | FGFR2IIIb Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
FGFR2IIIb Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-90 KDa and the accession number is P21802-3. | |||
TMPY-04216 | EphB2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
EphB2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.3 kDa and the accession number is P54763-3. | |||
TMPY-05602 | GITR/TNFRSF18 Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 Cells |
GITR/TNFRSF18 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 43.1 kDa and the accession number is Q9Y5U5-3. | |||
TMPY-04015 | COL9A1 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
COL9A1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 59.2 kDa and the accession number is P20849-3. | |||
TMPY-01692 | NETO1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Neuropilin tolloid-like 1 (NETO1), a complement C1r/C1s, Uegf, Bmp1 (CUB) domain-containing transmembrane protein, is a novel component of the NMDAR complex critical for maintaining the abundance of NR2A-containing NMDAR... | |||
TMPY-00715 | CD84 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CD84 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9UIB8-3. | |||
TMPY-05233 | GITR/TNFRSF18 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
GITR/TNFRSF18 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is Q9Y5U5-3. | |||
TMPY-03961 | Siglec-6 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Siglec-6 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 60.7 kDa and the accession number is O43699-3. | |||
TMPY-04408 | CAMKII beta/CAMK2B Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
Calcium/calmodulin-dependent protein kinase II beta (CAMK2B) is a member of the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. CaMKII is an important player in pro... | |||
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