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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T5315 | TCA1 | TCA-1,TCA 1 | Antibacterial , Antibiotic |
TCA1 (TCA 1) is a small molecule with activity against drug-resistant and persistent tuberculosis. | |||
T0653 | Tris(2-chloroethyl) phosphate | Disflamoll TCA,Fyrol CEF,Celluflex | Others |
Tris(2-chloroethyl) phosphate (Fyrol CEF) is served as flame retardants. | |||
T23426 | TC-A 2317 hydrochloride | Others , Aurora Kinase | |
TC-A 2317 hydrochloride is an Aurora kinase A inhibitor (Ki = 1.2 nM compared to 101 nM for inhibition of Aurora kinase B). It's selective over 60 other kinases (IC50: > 1000 nM). TC-A 2317 hydrochloride is also shown go... | |||
T38437 | NMTCA | N-Nitroso-2-methylthiazolidine4-carboxylicacid,NMTPRO,N-nitrosomethylthioproline | |
NMTCA (NMTPRO) is a sulfur-containing N-nitrosamino acid utilized as an endogenous nitrosation indicator in gas chromatography-thermal energy analysis. | |||
T22240 | Amitriptyline | Sigma receptor , 5-HT Receptor , Norepinephrine , Histamine Receptor | |
Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties. Amitriptyline is widely used to treat depression and neuropathic pain. | |||
T12232 | Nitroxazepine | CIBA 2330Go | Serotonin Transporter |
Nitroxazepine (CIBA 2330Go) is a serotonin-norepinephrine reuptake inhibitor, and treatment depression. Nitroxazepine is a tricyclic antidepressant (TCA) for the research of depression | |||
T21013 | Clomipramine | Chlorimipramine,Anafranil,Clomicalm,Anafranil (free base),Clomipramina | 5-HT Receptor |
Clomipramine (Clomicalm) is a tricyclic antidepressant (TCA). It is used for the treatment of the panic disorder, obsessive-compulsive disorder, major depressive disorder, and chronic pain. It may decrease the risk of su... | |||
T0991 | Desipramine hydrochloride | NSC-114901,Desmethylimipramine,JB-8181,EX-4355,Norimipramine,G-35020 | Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Adrenergic Receptor |
Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), Desipramine hydrochloride blocks the re-upt... | |||
T0943 | Carbamazepine | NSC 169864 | Mitophagy , Sodium Channel , Autophagy |
Carbamazepine (NSC-169864) is a tricyclic compound chemically related to tricyclic antidepressants (TCA) with anticonvulsant and analgesic properties. Carbamazepine exerts its anticonvulsant activity by reducing polysyna... | |||
T15132L | Dimetacrine tartrate | Linostil,Istonil,Istonyl,Miroistonil,MO 709 | |
Dimetacrine tartrate is a tricyclic antidepressant (TCA) used for the therapy of depression in Europe and formerly in Japan. | |||
T71773 | Levomepromazine Maleate | ||
Levomepromazine Maleate is a Tricyclic antidepressant (TCA), acting as a serotonin–norepinephrine reuptake inhibitor (SNRI) and also having other activities including antihistamine, antiadrenergic, antiserotonergic, anti... | |||
T69579 | Dothiepin HCl | ||
Dothiepin HCl is a Tricyclic antidepressant (TCA), acting as a serotonin–norepinephrine reuptake inhibitor (SNRI) and also having other activities including antihistamine, antiadrenergic, antiserotonergic, anticholinergi... | |||
T31824 | Fluoroglutamine (2S,4R) | FDG | |
Fluoroglutamine (2S,4R) is a Glutamine analog, not metabolized in the TCA cycle, but it can be incorporated into proteins and peptides. Fluoroglutamine (2S,4R) can be used as assess transporter (ASCT2) activity or protei... | |||
T61376 | Opipramol | ||
Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA) that primarily acts as a sigma (σ) receptor agonist, exhibiting potent interaction with sigma recognition sites (K i value of 50 nM). It can be employed i... | |||
T73796 | Acetyl coenzyme A lithium | ||
Acetyl-coenzyme A (Acetyl-CoA) lithium, a membrane-impermeant central metabolic intermediate, is integral to the TCA cycle and oxidative phosphorylation. It regulates cellular mechanisms by serving as the sole donor of a... | |||
T61741 | Azaphen dihydrochloride monohydrate | ||
Pipofezine(Azafen or Azaphen) is a potent inhibitor of the reuptake of serotonin. IC50 Value: Target: SSRIs Pipofezine is a tricyclic antidepressant (TCA) approved in Russia for the treatment ofdepression. In addition to... | |||
T73805 | Acetyl coenzyme A | ||
Acetyl-coenzyme A (Acetyl-CoA), a membrane-impermeant central metabolic intermediate, plays a crucial role in the TCA cycle and oxidative phosphorylation metabolism. It also serves as the sole donor of acetyl groups for ... | |||
T76124 | Acyl coenzyme A synthetase | ||
Acyl coenzyme A synthetase (ACS), also known as acetyl coenzyme A synthetase, plays a pivotal role in biochemical research. This enzyme catalyzes the activation of fatty acids via coenzyme A through a two-step thioesteri... | |||
T77253 | β-Nicotinamide adenine dinucleotide reduced dipotassium | ||
β-Nicotinamide adenine dinucleotide reduced dipotassium is an orally active, reduced coenzyme that functions as a donor of ADP-ribose units in ADP-ribosylation reactions, and as a precursor of cyclic ADP-ribose. It also ... | |||
T75430 | Succinic acid tromethamine | ||
Succinic acid tromethamine, a powerful and orally active anxiolytic agent, serves as an intermediate in the tricarboxylic acid (TCA) cycle. This compound is also a precursor for various industrially significant chemicals... | |||
TMIH-0184 | Desipramine-d3 HCl | ||
Desipramine-d3 HCl is a deuterated compound of Desipramine HCl. Desipramine HCl has a CAS number of 58-28-6. Desipramine Hydrochloride a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of d... | |||
T36401 | DCVC | ||
DCVC inhibits pathogen-stimulated TNF-α in human extra placental membranes in vitro.Target: TNF-αin vitro: DCVC inhibits pathogen stimulated cytokine release from tissue punch cultures. DCVC (5-50 μM) significantly inhib... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T4862 | Oxaloacetic acid | Endogenous Metabolite | |
Oxaloacetic acid, also known as oxosuccinic acid or oxalacetic acid, is a four-carbon dicarboxylic acid appearing as an intermediate of the citric acid cycle. In vivo, oxaloacetate (the ionized form of oxaloacetic acid) ... | |||
T8073 | Disodium succinate | Sodium succinate | Others |
Disodium succinate (Sodium succinate) is the sodium salt form of succinate, which is an important metabolite at the cross-road of several metabolic pathways and involved in the formation and elimination of reactive oxyge... | |||
T5980 | 2-Ketoglutaric acid | Tyrosinase , Endogenous Metabolite | |
2-Ketoglutaric acid is a key molecule in the tricarboxylic acid cycle,is also connected to glutamic acid and glutamine metabolisms through the transamination reactions. | |||
T5283 | NADH disodium salt | Disodium NADH,NADH, disodium salt hydrate | Others , Endogenous Metabolite |
NADH disodium salt (Disodium NADH) hydrate is the reduced form of nicotinamide adenine dinucleotide (NAD) that can donate electrons as part of a reducing reaction. In that process, NADH disodium salt hydrate becomes oxid... | |||
T4920 | 2-Ketoglutaric acid Sodium | Oxoglutaric acid,AKG,2-oxoglutarate monobasic,α-Ketoglutaric acid sodium salt | Tyrosinase , Endogenous Metabolite |
2-Ketoglutaric acid Sodium (AKG) is a key molecule in the TCA cycle. It can be produced from glutamate by oxidative deamination via glutamate dehydrogenase and as a product of pyridoxal phosphate-dependent transamination... | |||
T68351 | Homodestcardin | ||
Homodestcardin is a cyclic depsipeptide fungal metabolite that has been found in T. roseum and has immunosuppressant activity. It inhibits concanavalin A-induced proliferation of isolated mouse T cells. | |||
T4921 | Oxoadipic acid | 2-Oxoadipic acid | Endogenous Metabolite |
Oxoadipic acid (2-Oxoadipic acid) is a key metabolite of the essential amino acids tryptophan and lysine.Important metabolite between the TCA cycle and lysine biosynthesis. Of interest for research on mitochondrial metab... | |||
T8096 | Diethyl succinate | Others | |
Diethyl succinate is the diethyl ester of succinate and acts as an irritant. | |||
T4838 | (S)-Malic acid | L-(-)-Malic acid,(S)-(-)-HYDROXYSUCCINIC ACID,(S)-2-Hydroxysuccinic acid | Others , Endogenous Metabolite |
(S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a tart-tasting organic dicarboxylic acid that plays a role in many sour or tart foods. Apples contain malic acid, which contributes to the sourness of a green apple. Malic a... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-02538 | I-309 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
I-309 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 36.2 kDa and the accession number is P10146-1. | |||
TMPY-00695 | I-309 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
I-309 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35 kDa and the accession number is P22362. | |||
TMPY-03071 | I-309 Protein, Human, Recombinant | Human | E. coli |
I-309 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.7 kDa and the accession number is P22362. | |||
TMPY-02244 | CCL21 Protein, Human, Recombinant | Human | Baculovirus Insect Cells |
CCL21 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 12.3 kDa and the accession number is O00585. | |||
TMPH-01817 | OTCase Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline. The urea cycle ensures the detoxification of ammonia by converting it to urea for excretion. OTC... | |||
TMPH-02817 | OTCase Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline. The urea cycle ensures the detoxification of ammonia by converting it to urea for excretion. | |||
TMPH-02150 | SUCLG2 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the T... | |||
TMPY-04764 | PCK2 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
PCK2 promotes tumor initiation by lowering acetyl-CoA level through reducing the mitochondrial tricarboxylic acid (TCA) cycle. The levels of phosphoenolpyruvate carboxykinase isoform 2 (PCK2) are critical for the metabol... | |||
TMPH-02218 | JUN Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signali... | |||
TMPH-02219 | JUN Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signali... | |||
TMPY-04445 | PDK4 Protein, Mouse, Recombinant (His & GST) | Mouse | Baculovirus Insect Cells |
Pyruvate dehydrogenase kinase 4 (PDK4) is a mitochondrial protein that regulates the TCA cycle.PDK4, a vital mitochondrial protein, controls the switch between glycolysis and oxidative phosphorylation based upon nutrient... | |||
TMPY-02288 | Glyoxalase II/HAGH Protein, Human, Recombinant (His) | Human | E. coli |
HAGH (Hydroxyacylglutathione Hydrolase) is a Protein Coding gene. 3 alternative splicing and alternative initiation of human isoforms have been reported. The enzyme encoded by this gene is classified as a thioesterase an... | |||
TMPY-02003 | FH/Fumarate Hydratase Protein, Human, Recombinant (His) | Human | E. coli |
Fumarate Hydratase (FH) is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extende... | |||
TMPJ-01459 | FGF-21 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Fibroblast Growth Factor 21 (FGF21) is a growth factor that belongs to the FGF family. FGF family proteins play a central role during prenatal development and postnatal growth and regeneration of mamy tissues, by promoti... |
カタログ番号 | 製品名 | ||
---|---|---|---|
L8710 | Cuproptosis Compound Library | 400 compounds | |
TargetMol’s Cuproptosis Compound Library is a collection of 400 compounds related to copper-dependent death that can be used to study its mechanism and related diseases. | |||
L2550 | Glutamine Metabolism Compound Library | 565 compounds | |
A unique collection of 565 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and ... |