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Search Results for " TCA "

ターゲット

22

阻害剤

9

天然化合物

14

リコンビナントタンパク質

2

ライブラリー

カタログ番号 製品名 別名 ターゲット
T5315 TCA1 TCA-1,TCA 1 Antibacterial , Antibiotic
TCA1 (TCA 1) is a small molecule with activity against drug-resistant and persistent tuberculosis.
T0653 Tris(2-chloroethyl) phosphate Disflamoll TCA,Fyrol CEF,Celluflex Others
Tris(2-chloroethyl) phosphate (Fyrol CEF) is served as flame retardants.
T23426 TC-A 2317 hydrochloride Others , Aurora Kinase
TC-A 2317 hydrochloride is an Aurora kinase A inhibitor (Ki = 1.2 nM compared to 101 nM for inhibition of Aurora kinase B). It's selective over 60 other kinases (IC50: > 1000 nM). TC-A 2317 hydrochloride is also shown go...
T38437 NMTCA N-Nitroso-2-methylthiazolidine4-carboxylicacid,NMTPRO,N-nitrosomethylthioproline
NMTCA (NMTPRO) is a sulfur-containing N-nitrosamino acid utilized as an endogenous nitrosation indicator in gas chromatography-thermal energy analysis.
T22240 Amitriptyline Sigma receptor , 5-HT Receptor , Norepinephrine , Histamine Receptor
Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties. Amitriptyline is widely used to treat depression and neuropathic pain.
T12232 Nitroxazepine CIBA 2330Go Serotonin Transporter
Nitroxazepine (CIBA 2330Go) is a serotonin-norepinephrine reuptake inhibitor, and treatment depression. Nitroxazepine is a tricyclic antidepressant (TCA) for the research of depression
T21013 Clomipramine Chlorimipramine,Anafranil,Clomicalm,Anafranil (free base),Clomipramina 5-HT Receptor
Clomipramine (Clomicalm) is a tricyclic antidepressant (TCA). It is used for the treatment of the panic disorder, obsessive-compulsive disorder, major depressive disorder, and chronic pain. It may decrease the risk of su...
T0991 Desipramine hydrochloride NSC-114901,Desmethylimipramine,JB-8181,EX-4355,Norimipramine,G-35020 Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Adrenergic Receptor
Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), Desipramine hydrochloride blocks the re-upt...
T0943 Carbamazepine NSC 169864 Mitophagy , Sodium Channel , Autophagy
Carbamazepine (NSC-169864) is a tricyclic compound chemically related to tricyclic antidepressants (TCA) with anticonvulsant and analgesic properties. Carbamazepine exerts its anticonvulsant activity by reducing polysyna...
T15132L Dimetacrine tartrate Linostil,Istonil,Istonyl,Miroistonil,MO 709
Dimetacrine tartrate is a tricyclic antidepressant (TCA) used for the therapy of depression in Europe and formerly in Japan.
T71773 Levomepromazine Maleate
Levomepromazine Maleate is a Tricyclic antidepressant (TCA), acting as a serotonin–norepinephrine reuptake inhibitor (SNRI) and also having other activities including antihistamine, antiadrenergic, antiserotonergic, anti...
T69579 Dothiepin HCl
Dothiepin HCl is a Tricyclic antidepressant (TCA), acting as a serotonin–norepinephrine reuptake inhibitor (SNRI) and also having other activities including antihistamine, antiadrenergic, antiserotonergic, anticholinergi...
T31824 Fluoroglutamine (2S,4R) FDG
Fluoroglutamine (2S,4R) is a Glutamine analog, not metabolized in the TCA cycle, but it can be incorporated into proteins and peptides. Fluoroglutamine (2S,4R) can be used as assess transporter (ASCT2) activity or protei...
T61376 Opipramol
Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA) that primarily acts as a sigma (σ) receptor agonist, exhibiting potent interaction with sigma recognition sites (K i value of 50 nM). It can be employed i...
T73796 Acetyl coenzyme A lithium
Acetyl-coenzyme A (Acetyl-CoA) lithium, a membrane-impermeant central metabolic intermediate, is integral to the TCA cycle and oxidative phosphorylation. It regulates cellular mechanisms by serving as the sole donor of a...
T61741 Azaphen dihydrochloride monohydrate
Pipofezine(Azafen or Azaphen) is a potent inhibitor of the reuptake of serotonin. IC50 Value: Target: SSRIs Pipofezine is a tricyclic antidepressant (TCA) approved in Russia for the treatment ofdepression. In addition to...
T73805 Acetyl coenzyme A
Acetyl-coenzyme A (Acetyl-CoA), a membrane-impermeant central metabolic intermediate, plays a crucial role in the TCA cycle and oxidative phosphorylation metabolism. It also serves as the sole donor of acetyl groups for ...
T76124 Acyl coenzyme A synthetase
Acyl coenzyme A synthetase (ACS), also known as acetyl coenzyme A synthetase, plays a pivotal role in biochemical research. This enzyme catalyzes the activation of fatty acids via coenzyme A through a two-step thioesteri...
T77253 β-Nicotinamide adenine dinucleotide reduced dipotassium
β-Nicotinamide adenine dinucleotide reduced dipotassium is an orally active, reduced coenzyme that functions as a donor of ADP-ribose units in ADP-ribosylation reactions, and as a precursor of cyclic ADP-ribose. It also ...
T75430 Succinic acid tromethamine
Succinic acid tromethamine, a powerful and orally active anxiolytic agent, serves as an intermediate in the tricarboxylic acid (TCA) cycle. This compound is also a precursor for various industrially significant chemicals...
TMIH-0184 Desipramine-d3 HCl
Desipramine-d3 HCl is a deuterated compound of Desipramine HCl. Desipramine HCl has a CAS number of 58-28-6. Desipramine Hydrochloride a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of d...
T36401 DCVC
DCVC inhibits pathogen-stimulated TNF-α in human extra placental membranes in vitro.Target: TNF-αin vitro: DCVC inhibits pathogen stimulated cytokine release from tissue punch cultures. DCVC (5-50 μM) significantly inhib...

Compounds

TCA1
T5315
Synonym: TCA-1,TCA 1
Target: Antibacterial, Antibiotic
Tris(2-chloroethyl) phosphate
T0653
Synonym: Disflamoll TCA,Fyrol CEF,Celluflex
Target: Others
TC-A 2317 hydrochloride
T23426
Synonym:
Target: Others, Aurora Kinase
NMTCA
T38437
Synonym: N-Nitroso-2-methylthiazolidine4-carboxylicacid,NMTPRO,N-nitrosomethylthioproline
Target:
Amitriptyline
T22240
Synonym:
Target: Sigma receptor, 5-HT Receptor, Norepinephrine, Histamine Receptor
Nitroxazepine
T12232
Synonym: CIBA 2330Go
Target: Serotonin Transporter
Clomipramine
T21013
Synonym: Chlorimipramine,Anafranil,Clomicalm,Anafranil (free base),Clomipramina
Target: 5-HT Receptor
Desipramine hydrochloride
T0991
Synonym: NSC-114901,Desmethylimipramine,JB-8181,EX-4355,Norimipramine,G-35020
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Adrenergic Receptor
Carbamazepine
T0943
Synonym: NSC 169864
Target: Mitophagy, Sodium Channel, Autophagy
Dimetacrine tartrate
T15132L
Synonym: Linostil,Istonil,Istonyl,Miroistonil,MO 709
Target:
Levomepromazine Maleate
T71773
Synonym:
Target:
Dothiepin HCl
T69579
Synonym:
Target:
Fluoroglutamine (2S,4R)
T31824
Synonym: FDG
Target:
Opipramol
T61376
Synonym:
Target:
Acetyl coenzyme A lithium
T73796
Synonym:
Target:
Azaphen dihydrochloride monohydrate
T61741
Synonym:
Target:
Acetyl coenzyme A
T73805
Synonym:
Target:
Acyl coenzyme A synthetase
T76124
Synonym:
Target:
β-Nicotinamide adenine dinucleotide reduced dipotassium
T77253
Synonym:
Target:
Succinic acid tromethamine
T75430
Synonym:
Target:
Desipramine-d3 HCl
TMIH-0184
Synonym:
Target:
DCVC
T36401
Synonym:
Target:
カタログ番号 製品名 別名 ターゲット
T4862 Oxaloacetic acid Endogenous Metabolite
Oxaloacetic acid, also known as oxosuccinic acid or oxalacetic acid, is a four-carbon dicarboxylic acid appearing as an intermediate of the citric acid cycle. In vivo, oxaloacetate (the ionized form of oxaloacetic acid) ...
T8073 Disodium succinate Sodium succinate Others
Disodium succinate (Sodium succinate) is the sodium salt form of succinate, which is an important metabolite at the cross-road of several metabolic pathways and involved in the formation and elimination of reactive oxyge...
T5980 2-Ketoglutaric acid Tyrosinase , Endogenous Metabolite
2-Ketoglutaric acid is a key molecule in the tricarboxylic acid cycle,is also connected to glutamic acid and glutamine metabolisms through the transamination reactions.
T5283 NADH disodium salt Disodium NADH,NADH, disodium salt hydrate Others , Endogenous Metabolite
NADH disodium salt (Disodium NADH) hydrate is the reduced form of nicotinamide adenine dinucleotide (NAD) that can donate electrons as part of a reducing reaction. In that process, NADH disodium salt hydrate becomes oxid...
T4920 2-Ketoglutaric acid Sodium Oxoglutaric acid,AKG,2-oxoglutarate monobasic,α-Ketoglutaric acid sodium salt Tyrosinase , Endogenous Metabolite
2-Ketoglutaric acid Sodium (AKG) is a key molecule in the TCA cycle. It can be produced from glutamate by oxidative deamination via glutamate dehydrogenase and as a product of pyridoxal phosphate-dependent transamination...
T68351 Homodestcardin
Homodestcardin is a cyclic depsipeptide fungal metabolite that has been found in T. roseum and has immunosuppressant activity. It inhibits concanavalin A-induced proliferation of isolated mouse T cells.
T4921 Oxoadipic acid 2-Oxoadipic acid Endogenous Metabolite
Oxoadipic acid (2-Oxoadipic acid) is a key metabolite of the essential amino acids tryptophan and lysine.Important metabolite between the TCA cycle and lysine biosynthesis. Of interest for research on mitochondrial metab...
T8096 Diethyl succinate Others
Diethyl succinate is the diethyl ester of succinate and acts as an irritant.
T4838 (S)-Malic acid L-(-)-Malic acid,(S)-(-)-HYDROXYSUCCINIC ACID,(S)-2-Hydroxysuccinic acid Others , Endogenous Metabolite
(S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a tart-tasting organic dicarboxylic acid that plays a role in many sour or tart foods. Apples contain malic acid, which contributes to the sourness of a green apple. Malic a...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-02538 I-309 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
I-309 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 36.2 kDa and the accession number is P10146-1.
TMPY-00695 I-309 Protein, Human, Recombinant (hFc) Human HEK293 Cells
I-309 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35 kDa and the accession number is P22362.
TMPY-03071 I-309 Protein, Human, Recombinant Human E. coli
I-309 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.7 kDa and the accession number is P22362.
TMPY-02244 CCL21 Protein, Human, Recombinant Human Baculovirus Insect Cells
CCL21 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 12.3 kDa and the accession number is O00585.
TMPH-01817 OTCase Protein, Human, Recombinant (His & SUMO) Human E. coli
Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline. The urea cycle ensures the detoxification of ammonia by converting it to urea for excretion. OTC...
TMPH-02817 OTCase Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline. The urea cycle ensures the detoxification of ammonia by converting it to urea for excretion.
TMPH-02150 SUCLG2 Protein, Human, Recombinant (His & SUMO) Human E. coli
GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the T...
TMPY-04764 PCK2 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
PCK2 promotes tumor initiation by lowering acetyl-CoA level through reducing the mitochondrial tricarboxylic acid (TCA) cycle. The levels of phosphoenolpyruvate carboxykinase isoform 2 (PCK2) are critical for the metabol...
TMPH-02218 JUN Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signali...
TMPH-02219 JUN Protein, Human, Recombinant (His & Myc) Human E. coli
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signali...
TMPY-04445 PDK4 Protein, Mouse, Recombinant (His & GST) Mouse Baculovirus Insect Cells
Pyruvate dehydrogenase kinase 4 (PDK4) is a mitochondrial protein that regulates the TCA cycle.PDK4, a vital mitochondrial protein, controls the switch between glycolysis and oxidative phosphorylation based upon nutrient...
TMPY-02288 Glyoxalase II/HAGH Protein, Human, Recombinant (His) Human E. coli
HAGH (Hydroxyacylglutathione Hydrolase) is a Protein Coding gene. 3 alternative splicing and alternative initiation of human isoforms have been reported. The enzyme encoded by this gene is classified as a thioesterase an...
TMPY-02003 FH/Fumarate Hydratase Protein, Human, Recombinant (His) Human E. coli
Fumarate Hydratase (FH) is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extende...
TMPJ-01459 FGF-21 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Fibroblast Growth Factor 21 (FGF21) is a growth factor that belongs to the FGF family. FGF family proteins play a central role during prenatal development and postnatal growth and regeneration of mamy tissues, by promoti...
カタログ番号 製品名
L8710 Cuproptosis Compound Library

400 compounds
TargetMol’s Cuproptosis Compound Library is a collection of 400 compounds related to copper-dependent death that can be used to study its mechanism and related diseases.
L2550 Glutamine Metabolism Compound Library

565 compounds
A unique collection of 565 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and ...