|
T1371 |
1H-1,2,4-Triazole-3-carboxylic acid
|
|
Others
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|
It has been granted to have property to inhibit protein isoprenyl transferases. |
|
T77765 |
FSEN1
|
3-(4-bromophenyl)-6-((4-(4-methoxyphenyl)piperazin-1-yl)methyl)thiazolo[2,3-c][1,2,4]triazole |
Ferroptosis
|
|
FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM. FSEN1 induces iron death in cancer cells by inhibiting FSP1. FSEN1 can be used to prevent and treat cancer. |
|
T41244 |
Triticonazole
|
|
Antifungal
|
|
Triticonazole is a triazole pesticide and fungicide. Triticonazole shows endocrine disrupting activities. |
|
T7867 |
Flutriafol
|
|
NMDAR
,
Antifungal
|
|
Flutriafol is a pesticide, demethylation inhibitor, and NMDA receptor agonist |
|
T17676 |
Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA
|
|
Others
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|
Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA is a double claevable 3-unit and 4-unit PEG linker for antibody-drug-conjugation (ADC). |
|
T67498 |
3-Amino-1,2,4-triazole
|
Amitrole,3-AT,1H-1,2,4-Triazol-5-amine,Trapidil impurity B |
Reactive Oxygen Species
|
|
3-Amino-1,2,4-triazole (Trapidil impurity B) is an inhibitor of catalase, capable of inducing the compensatory mechanism for hydrogen peroxide detoxification. This mechanism involves increasing the activities of glutathi... |
|
T12103 |
MR-L2
|
|
PDE
|
|
MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4). |
|
T9998 |
MIND4-19
|
|
Sirtuin
|
|
MIND4-19 is an inhibitor of SIRT2 with antitumor activity. |
|
T67137 |
1-Methyl-1,2,4-triazole
|
|
|
|
1-Methyl-1,2,4-triazole is a useful organic compound for research related to life sciences. The catalog number is T67137 and the CAS number is 6086-21-1. |
|
T0120 |
Voriconazole
|
UK-109496 |
Antifection
,
Antifungal
|
|
Voriconazole (UK-109496) is a triazole antifungal agent that specifically inhibits STEROL 14-ALPHA-DEMETHYLASE and CYTOCHROME P-450 CYP3A. |
|
T78235 |
4-Phenyl-1H-1,2,3-triazole
|
|
Indoleamine 2,3-Dioxygenase (IDO)
|
|
4-Phenyl-1H-1,2,3-triazole, an inhibitor of the enzyme IDO1 (IC50: 60 µM), is utilized in cancer research [1]. |
|
T67127 |
1H-1,2,4-Triazole-1-carboximidamide hydrochloride
|
|
|
|
1H-1,2,4-Triazole-1-carboximidamide hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T67127 and the CAS number is 19503-26-5. |
|
T2305 |
Isavuconazole
|
BAL-4815,RO-0094815 |
P450
,
Antibiotic
,
Antifungal
|
|
Isavuconazole (RO-0094815)(BAL-4815; RO-0094815) is the active component of the new azole antifungal agent BAL8557 with MIC(50)s/MIC(90)s ranged from 0.002/0.004 mg/liter for C. albicans to 0.25/0.5 mg/liter for C. glabr... |
|
T66475 |
Methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate
|
|
|
|
Methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T66475 and the CAS number is 217448-86-7. |
|
T67440 |
Ethyl 1-(4-bromophenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylate
|
|
|
|
Ethyl 1-(4-bromophenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T67440 and the CAS number is 361990-21-8. |
|
T67318 |
1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole methanesulfonate
|
|
|
|
1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole methanesulfonate is a useful organic compound for research related to life sciences. The catalog number is T67318 and the CAS number is 86386-77-8. |
|
TNU0339 |
Ribavirin carboxylic acid
|
|
|
|
Nucleoside Derivatives - Other modified nucleosides; Drugs and Inhibitors; Ribavirin related compound A; metabolite of Ribavirin |
|
T14871 |
Carboxyamidotriazole Orotate
|
L-651582 Orotate,CAI Orotate |
Calcium Channel
|
|
Carboxyamidotriazole Orotate (L-651582 Orotate) is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways. Carboxyamidotriazole Orotate (L-651582 Orotate) is the o... |
|
T5953 |
1-Aminobenzotriazole
|
3-Aminobenzotriazole,ABT |
P450
|
|
1-Aminobenzotriazole (ABT) (ABT) is a non-specific cytochrome P450 (CYP) inhibitor. |
|
T14872 |
Carboxyamidotriazole
|
CAI,L-651582 |
Calcium Channel
|
|
Carboxyamidotriazole is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways. It shows anti-inflammatory, anti-tumor, and antiangiogenic effects. |
|
T25403 |
Farnesylthiotriazole
|
|
|
|
Farnesylthiotriazole is a persistent PKC activator agent. |
|
T7152 |
Ravuconazole
|
BMS-207147,ER-30346 |
Antifungal
|
|
Ravuconazole (ER-30346) is a potent triazole antifungal that potently inhibits a wide range of fungi. |
|
T20058 |
Prothioconazole
|
HSDB7893,HSDB-7893,Proline 480 SC Fungicide,JAU 6476,HSDB 7893 |
Antifungal
|
|
Prothioconazole (Proline 480 SC Fungicide) is a chiral triazole fungicide in plant pathogen control. |
|
T26829 |
Bitertanol
|
KWG-0599,KWG0599,Baycor,Biloxazol,KWG 0599,Sibutol |
Antifungal
|
|
Bitertanol (KWG 0599) is a triazole fungicide. Bitertanol inhibits demethylation, disrupts membrane function, and prevents sterol synthesis. |
|
T11070 |
DO34 analog
|
|
Others
|
|
DO34 analog is a triazole DAGL(α) inhibitor. |
|
T2523 |
Rufinamide
|
CGP 33101,E 2080,RUF 331 |
Sodium Channel
|
|
Rufinamide (E 2080), a triazole derivative, is used as voltage-gated sodium channel blocker for the treatment of seizure disorders. |
|
T7866 |
Difenoconazole
|
|
Others
,
Antifungal
|
|
Difenoconazole is a broad-spectrum triazole fungicide that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol, which results in disruption of the fungal cell ... |
|
T2199 |
Myclobutanil
|
Systhane |
Antifungal
|
|
Myclobutanil (Systhane) is a triazole chemical used as a fungicide. It is a steroid demethylation inhibitor, specifically inhibiting ergosterol biosynthesis. Ergosterol is a critical component of fungal cell membranes. |
|
T15033 |
Cyproconazole
|
|
Antibacterial
|
|
Cyproconazole is a triazole fungicide. It is used agriculturally for protection of crops against a wide variety of fungal pathogens. |
|
T7086 |
Tris(benzyltriazolylmethyl)amine
|
TBTA |
Others
|
|
Tris(benzyltriazolylmethyl)amine (TBTA) is a tertiary amine with three 1, 2, 3-triazole groups. It complexes with, and stabilizes, copper(I) to accelerate azide-alkyne cycloadditions, as used in click chemistry. |
|
T67988 |
Embeconazole
|
R 120758,CS 758 |
Antifungal
|
|
Embeconazole (R 120758) is a triazole antifungal agent.Embeconazole has strong in vitro activity against clinically important fungi such as Candida, Aspergillus and Cryptococcus neoformans. |
|
T27617 |
Inz-1
|
|
P450
|
|
Inz-1 is an effective and fungal-selective inhibitor of mitochondrial cytochrome bc1 with IC50s of 8.092 and 45.320 μM for yeast and human. Inz-1 reverses Fluconazole or other triazole antifungals’ resistance in the path... |
|
T67766 |
HHS-0701
|
|
Others
|
|
HHS-0701 is a sulfur-triazole exchange (SuTEx) ligand. HHS-0701 is a potent inhibitor of tyrosine-reactive prostaglandin reductase 2 (PTGR2). HHS-0701 can block PTGR2 metabolism of the lipid substrate 15-Keto-PGE2. |
|
T2213 |
Terconazole
|
Gyno-Terazol,Terazol 3,Terazol 7,Triaconazole,R42470 |
Antifection
,
Antifungal
|
|
Terconazole (Terazol 7) is a synthetic triazole derivative structurally related to fluconazole, antifungal Terconazole seems to disrupt cell wall synthesis by inhibiting biosynthesis of ergosterol or other sterols, damag... |
|
T60929 |
Brassinazole
|
(2S,3R)-Brassinazole |
Others
|
|
Brassinazole is a selective inhibitor of triazole-type steroid (BR) biosynthesis.Brassinazole can be used to modulate the oleuropein steroid (BR) signaling pathway, which is used to regulate plant xylem growth and develo... |
|
T5966 |
Hexaconazole
|
(-)-Hexaconazol |
Reactive Oxygen Species
,
Antifungal
|
|
Hexaconazole ((-)-Hexaconazol) is a broad-spectrum triazole fungicide that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol, which results in disruption of ... |
|
T38273 |
Paclobutrazol
|
(2R,3R)-Paclobutrazol,(R,R)-paclobutrazol,2R,3R-Paclobutrazol |
Antifungal
|
|
Paclobutrazol ((R,R)-paclobutrazol) is a triazole-containing plant growth retardant that is known to inhibit the biosynthesis of gibberellins.1,2It also has antifungal activities.3PBZ, which is transported acropetally in... |
|
T17731L |
CL2A-SN-38 DCA 1279680-68-0(free base)
|
|
Others
|
|
CL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC).. CL2A-SN-38 is composed of a potent a DNA Topoisomerase I inhibito... |
|
T3934 |
Isavuconazonium sulfate
|
|
Antifungal
|
|
Isavuconazonium sulfate is hydrolyzed by plasma esterases to yield the active moiety isavuconazole. Isavuconazole binds to and inhibits the fungal cytochrome P450 family enzyme lanosterol 14-alpha-demethylase (CYP51), wh... |
|
T28717 |
Sch 39304
|
Sch-39304,Sch39304 |
|
|
Sch 39304 is an oral triazole antifungal. |
|
T37796 |
Voriconazole N-oxide
|
|
|
|
Voriconazole N-oxide is a major metabolite of the triazole antifungal voriconazole . It is formed via oxidation of voriconazole by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C19. |
|
T21276 |
Amisulbrom
|
|
|
|
Amisulbrom is classified under the triazole group of fungicides. |
|
T16714 |
Saperconazole
|
R66905 |
Others
|
|
Saperconazole is a broad-spectrum antifungal triazole (MIC90: 0.19 mg/L). |
|
T61960 |
Fluconazole mesylate
|
|
|
|
Fluconazole (mesylate) is a triazole antifungal drug. Fluconazole (mesylate) can used in the treatment and prevention of superficial and systemic fungal infections |
|
T12522 |
Posaconazole-D4
|
SCH 56592-D4 |
Others
|
|
Posaconazole-D4, a deuterium-labeled variant of Posaconazole, is a broad-spectrum, second-generation triazole with antifungal activity. |
|
T12523 |
Posaconazole-D5
|
SCH 56592-D5 |
Others
|
|
Posaconazole-D5, a deuterium-labeled variant of Posaconazole, is a second-generation, broad-spectrum triazole compound with antifungal activity. |
|
T30272 |
Azido-PEG12-t-butyl ester
|
|
|
|
Azido-PEG12-t-butyl ester is a PEG derivative containing an azide group and a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Ch... |
|
T23174 |
Posaconazole hydrate
|
|
Others
|
|
Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity. Posaconazole is a sterol C14ɑ demethylase inhibitor (IC50: 0.25 nM). Posaconazole strongly inhibits 14-alpha demethylase, a... |
|
T11679 |
Isavuconazole-d4
|
BAL-4815 D4,RO-0094815 D4,Isavuconazole D4 |
Others
|
|
Isavuconazole D4 is a deuterium labeled Isavuconazole. Isavuconazole is a triazole prodrug with antifungal activity against yeasts, molds, and dimorphic fungi. |
|
T11585 |
Hydroxy Itraconazole D8
|
R-63373 D8 |
Others
|
|
Hydroxy Itraconazole D8 is the deuterium-labeled Hydroxy Itraconazole. Hydroxy Itraconazole is an active metabolite of Itraconazole, which is a triazole antifungal agent. |
