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ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T15391	Glufosinate ammonium		Others
	Glufosinate ammonium is a phosphinic acid analog of glutamic acid and an herbicide with neurotoxic activity. It is converted by plant cells into PT (L-phosphinothricin).		Others
T15390	Glufosfamide	D 19575,Glucosylifosfamide mustard	Others
	Glufosfamide is a novel oxazolophosphamide compound with anticancer activity for the study of advanced non-small cell lung cancer.		Others
T20029	Buformin hydrochloride	NSC528218,NSC-528218,NSC 528218	AMPK
	Buformin hydrochloride (NSC-528218) is a potent AMPK activator,an oral antidiabetic drug of the biguanide class. Buformin delays the absorption of glucose from the gastrointestinal tract increases insulin sensitivity and...		AMPK
T9574	Lufotrelvir	PF-07304814	SARS-CoV
	Lufotrelvir (PF-07304814) is a small molecule inhibitor of the SARS CoV-2 3CL protease for the treatment of COVID-19 with broad-spectrum anti-SARS activity for the study of novel coronavirus infections.		SARS-CoV
T31224	Piflufolastat	DCFPYL	Epigenetic Reader Domain
	Piflufolastat (DCFPYL) is a PET imaging agent for prostate cancer PSMA. It is a fluorinated prostate-specific membrane antigen (PSMA) preparation. Piflufolastat can be used to prepare piflufolastat F 18 (DCFPyL F-18).		Epigenetic Reader Domain
T68146	Sufotidine	AH 25352X,AH25352X,AH-25352X	Histamine Receptor
	Sufotidine (AH 25352X) is a highly selective competitive H2 receptor antagonist.		Histamine Receptor
T131542	Arenobufagin (Arenobufogenin)
	Arenobufagin (Arenobufogenin) is a useful organic compound for research related to life sciences and the catalog number is T131542.
T20772	Crufomate	Ruelene,M 1261,M1261,Crufomatum,M-1261
	Crufomate, an insecticide, is used extensively for the control of hornflies, cattle grubs and cattle lice.
T75992	Buforin II
	Buforin II, a powerful antimicrobial peptide originating from Buforin I (a protein extracted from the Asian toad Bufo bufo gargarizans's stomach), exhibits broad-spectrum antimicrobial properties against both Gram-positi...
T15391L	Glufosinate		Others
	Glufosinate, a phosphinic acid analog of glutamic acid, is a herbicide that is converted by plant cells into PT (L-phosphinothricin). It has neurotoxic activity.		Others
T131543	Gamabufotalin (Gamabufagin; Gamabufogenin)
	Gamabufotalin (Gamabufagin; Gamabufogenin) is a useful organic compound for research related to life sciences and the catalog number is T131543.
T10116	3-O-Acetylbufotalin		Others
	3-O-Acetylbufotalin is a derivate of bufadienolide with anti-cancer activity.		Others
T30610	Bufotoxin	Vulgarobufotoxin
	Bufotoxin, a toxic steroid lactone, exists in the parotoid glands, skin, and poison of many toads and other amphibians, and in some plants and mushrooms.
T23837	Buformin	W37,W 37,H 224,W-37
	Buformin (1-butylbiguanide) is an oral antidiabetic drug of the biguanide class. It also inhibits the synthesis of glucose by the liver. Buformin delays absorption of glucose from the gastrointestinal tract increases ins...
T32590	Lauformine
	Lauformine is a isoquinoline alkaloid.
T61011	Izuforant
	Izuforant (JW1601) (Compound 24) has potent anti-inflammatory and anti-pruritic activities. Izuforant has a binding affinity for human serotonin 3 receptor (h5-HT3R) with an IC50 value of 9.1 μM. Izuforant is also an ora...
T124283	5beta-Hydroxybufotalin
	5beta-Hydroxybufotalin is a useful organic compound for research related to life sciences and the catalog number is T124283.
T125720	Ajuforrestin A
	Ajuforrestin A is a useful organic compound for research related to life sciences and the catalog number is T125720.
T27146	Denufosol tetrasodium	INS37217,INS 37217,INS-37217
	Denufosol is a P2Y2 agonist potentially for the treatment of cystic fibrosis.
T76864	Enapotamab		TAM Receptor
	Enapotamab is an AXL/UFO-related antibody that can be used to synthesize antibody-drug couplings (Enapotamab Vedotin).		TAM Receptor

Compounds

Synonym: D 19575,Glucosylifosfamide mustard

Target: Others

Buformin hydrochloride

T20029

Synonym: NSC528218,NSC-528218,NSC 528218

Target: Epigenetic Reader Domain

Sufotidine

T68146

Synonym: AH 25352X,AH25352X,AH-25352X

Target: Histamine Receptor

Arenobufagin (Arenobufogenin)

Synonym: Ruelene,M 1261,M1261,Crufomatum,M-1261

Gamabufotalin (Gamabufagin; Gamabufogenin)

Synonym: Vulgarobufotoxin

Target:

Buformin

T23837

Synonym: W37,W 37,H 224,W-37

5beta-Hydroxybufotalin

Denufosol tetrasodium

T27146

Synonym: INS37217,INS 37217,INS-37217

カタログ番号	製品名	別名	ターゲット
T4A2458	Resibufogenin	Bufogenin,Recibufogenin	Others
	1. Resibufogenin (Bufogenin) is a cytotoxic steroid isolated from the Chinese drug ChanSu. 2. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological eff...		Others
T4A2399	Cinobufotalin		IL Receptor , Akt , MRP , P-gp
	Cinobufotalin is a main cardiac toxin in toad, it is a novel anti-HCC agent, it induces growth inhibition and apoptosis in cultured HCC cells through ceramide production. Cinobufotalin is also an effective reversal agent...		IL Receptor , Akt , MRP , P-gp
T5A2461	Bufotalin	Bufotaline	Apoptosis , Others , Reactive Oxygen Species
	1. Bufotalin (Bufotaline)e is a kind of poisonous secretions of toads.		Apoptosis , Others , Reactive Oxygen Species
TN7062L	Bufotenidine hydrochloride(487-91-2 Free base)
	Bufotenidine hydrochloride(487-91-2 Free base) is a natural product for research related to life sciences. The catalog number is TN7062L and the CAS number is 40581-89-3.
T4A2456	Gamabufotalin	Gamabufagin	COX
	1. Gamabufotalin (Gamabufagin) , a major bufadienolide of Chansu, has been used for treatment of COX-2-mediated diseases and cancer therapy due to its desirable metabolic stability and less adverse effect.		COX
TN3035	4'-Hydroxy-2-O-methylanigorufone		Others
	9-(4'-Hydroxyphenyl)-2-methoxyphenalen-1-one(4'-Hydroxy-2-O-methylanigorufone) is a phytoalexin. It shows a strong α-glucosidase inhibitory effect.		Others
T82807	Bufospirostenin A
	Bufospirostenin A represents the inaugural (spirostanol) compound isolated from an animal source.
T5527	Anigorufone		Antifection
	Anigorufone is a phytoalexin, it shows striking antinematode activity. Anigorufone has shown inhibitory activity on the growth of the germinative tube of Fusarium oxysporum f. sp. cubense race 4.		Antifection
TN1912	Marinobufogenin	Marinobufagenin	ATPase , EGFR
	Marinobufagenin, a cardiotonic steroid, its increased concentrations are important in the cardiac disease and oxidant stress state seen with renal failure.		ATPase , EGFR
T31876	Frangufoline
	Frangufoline is a sedative 14-membered frangulanine-type cyclopeptide alkaloid.
T82808	Bufoserotonin C
	Bufoserotonin C, an indole alkaloid derived from the traditional Chinese medicine Chansu, exhibits antitumor activity and demonstrates an IC50 value of 34.3 μM in A549 cells [1] [2].
T83282	5β-Hydroxybufotalin
	5β-Hydroxybufotalin (compound 6), a natural anticancer agent derived from the traditional Chinese medicine Ch'an Su [1], exhibits potent inhibitory effects on cancer cell proliferation.
TN2877	3,4-Dihydroxy-2-O-methylanigorufone		Others
	3,4-Dihydroxy-2-O-methylanigorufone is a natural product for research related to life sciences. The catalog number is TN2877 and the CAS number is 1392307-42-4.		Others
TN1572	Desacetylcinobufotalin		Others
	Desacetylcinobufotalin has significant antitumor activity through induction apoptosis via mitochondria pathway, it also shows potent cytotoxic activities against HL-60 cell lines.		Others
TN1200	19-Oxocinobufotalin		Others
	19-Oxocinobufotalin 3-adipoylarginine ester shows significant inhibition effect against human hepatocellular carcinoma cell line SMMC-7721 in vitro.		Others
TN2787	2-O-Methylanigorufone		Others
	2-O-Methylanigorufone is a natural product from Monochoria vaginalis.		Others
TN4238	Hydroxyanigorufone		Others
	Hydroxyanigorufone is a natural product from Musa itinerans Cheesm.		Others

天然物製品

Resibufogenin

T4A2458

Synonym: Bufogenin,Recibufogenin

Target: IL Receptor, Akt, MRP, P-gp

Bufotalin

T5A2461

Synonym: Bufotaline

Target: Apoptosis, Others, Reactive Oxygen Species

Bufotenidine hydrochloride(487-91-2 Free base)

4'-Hydroxy-2-O-methylanigorufone

Synonym: Marinobufagenin

3,4-Dihydroxy-2-O-methylanigorufone

TN2877

Synonym:

Target: Others

Desacetylcinobufotalin

2-O-Methylanigorufone

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-01601	AXL Protein, Human, Recombinant (His)	Human	HEK293 Cells
	AXL Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.5 kDa and the accession number is AAB20305.1.
TMPJ-00449	AXL Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	AXL Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-115 KDa and the accession number is AAA61243.
TMPJ-00399	AXL Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	AXL Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession number is Q00993.
TMPY-01021	AXL Protein, Mouse, Recombinant (His & hFc)	Mouse	HEK293 Cells
	AXL Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 74.5 kDa and the accession number is Q00993.
TMPY-06478	AXL Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	AXL Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 72.11 kDa and the accession number is AAH32229.1.
TMPY-01364	AXL Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	AXL Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.8 kDa and the accession number is Q00993.
TMPK-00472	AXL Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpre...
TMPK-00407	AXL Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpre...
TMPK-00408	AXL Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpre...
TMPK-00410	AXL Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated	Human	HEK293 Cells
	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpre...
TMPJ-01081	Dtk Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse homologues of chicken cEyk)constitute a new receptor tyrosine kinase subfamily. The extracellular domain of these proteins contain two Ig-like motifs an...