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T22554 |
Adenosine Kinase Inhibitor (hydrate)
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Others
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Adenosine kinase is the key metabolizing enzyme regulating cellular adenosine concentrations. Inhibition of adenosine kinase can selectively enhance the protective actions of adenosine during tissue trauma without produc... |
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T14944 |
CGS 15943
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PI3K
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Adenosine Receptor
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CGS 15943 is an orally bioavailable non-xanthine antagonist of Adenosine Receptor. In transfected CHO cells, its Ki for human A1, A2A, A2B, and A3 Adenosine Receptors are 3.5, 4.2, 16, and 50 nM , respectively. |
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T4668 |
ABT-702 dihydrochloride
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Adenosine Receptor
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ABT-702 dihydrochloride is a potent adenosine kinase (AK) inhibitor. |
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T6745 |
5-Iodotubercidin
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5-ITu,NSC 113939 |
Adenosine Receptor
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5-Iodotubercidin (NSC-113939) is a potent adenosine kinase inhibitor with IC50 of 26 nM. It inhibits nucleoside transporter, CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2 and PKC. |
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T21017 |
5'-Amino-5'-deoxyadenosine
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5' Amino 5' deoxyadenosine,5'Amino5'deoxyadenosine,Nsc 238990,NH2dAdo |
Apoptosis
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Adenosine Receptor
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5'-Amino-5'-deoxyadenosine (NH2dAdo) is an adenosine kinase inhibitor targeting malignant tumors of the inert lymphatic system with antitumor and anticancer effects.The anticancer mechanism of 5'-Amino-5'-deoxyadenosine ... |
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T2615 |
Flavopiridol hydrochloride
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Alvocidib Hydrochloride,NSC 649890,MDL 107826A,HL 275,FLAVOPIRIDOL HCL,NSC 649890 HCl |
HIV Protease
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CDK
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Autophagy
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Flavopiridol hydrochloride (MDL 107826A) is a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of ... |
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T1433 |
Ritodrine hydrochloride
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DU21220,Ritodrine HCl,NSC 291565 |
Adrenergic Receptor
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Ritodrine hydrochloride (NSC 291565) binds to and activates beta-2 adrenergic receptors of myometrial cells in the uterus, which decreases the intensity and frequency of uterine contractions. Ritodrine hydrochloride (NS... |
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T25145 |
Benzoadenosine
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NSC 287022,NSC287022,NSC-287022,Lin-benzoadenosine |
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Benzoadenosine suppresses kinase activity slightly less than does adenosine. |
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T21018 |
Anisodine hydrobromide
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Anisodine hydrobromide is an inhibitor of adenosine kinase. |
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T70617 |
GP-1-515
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GP-1-515 is an adenosine kinase inhibitor with anti-inflammatory effects. |
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T38346 |
ABT 702 hydrochloride
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Potent non-nucleoside adenosine kinase inhibitor (IC50 = 1.7 nM), selective over other sites of adenosine interaction (A1, A2A and A3 receptors, adenosine transporter and adenosine deaminase). Displays oral activity in a... |
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TP1314 |
AMARA peptide TFA (163560-19-8 free base)
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AMARA peptide TFA |
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AMARA peptide (TFA) is a substrate for salt-induced kinase (SIK) and adenosine activated protein kinase (AMPK). |
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T35574 |
Adenosine 5'-phosphosulfate (sodium salt)
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Adenosine 5'-phosphosulfate is an ATP and sulfate competitive inhibitor of ATP sulfurylase in humans, S. cerevisiae, and P. chrysogenum (Ki = 18, 2500, and 1500 nM, respectively). Adenosine 5'-phosphosulfate also inhibit... |
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T75984 |
AMARA peptide TFA
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AMARA peptide (TFA) serves as a substrate for both salt-inducible kinase (SIK) and adenosine monophosphate-activated protein kinase (AMPK). |
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T26475 |
A-286501
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A-286501 is an orally active adenosine kinase inhibitor (IC50=0.47 nM). A-286501 effectively attenuates nociception by a non-opioid, non-non-steroidal anti-inflammatory drug ADO, receptor mediated mechanism. |
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T62227 |
GP3269
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GP3269 is a selective, potent, orally active human adenosine kinase (AK) inhibitor (IC50: 11 nM) with anticonvulsant effects in rats. |
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T68267 |
RO5068760
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RO5068760 , a substituted hydantoin, is a potent, highly selective, non-adenosine triphosphate (ATP)-competitive MEK1/2 inhibitors. RO5068760 shows significant efficacy in a broad spectrum of tumors with aberrant mitogen... |
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T73525 |
ML202
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ML202 is a highly specific allosteric activator of human pyruvate kinase M2 (hPK-M2), enhancing the cooperativity of phosphoenolpyruvate (PEP) binding, with negligible effect on adenosine diphosphate (ADP) binding. |
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T74033 |
6-Me-ATP
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6-Me-ATP (N6-Methyl-ATP), a N6-modified adenosine triphosphate (ATP) derivative, exhibits strong binding affinity for glycogen synthase kinase 3 (GSK3) and acts as the phosphate group donor in GSK3β-catalyzed phosphoryla... |
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T83806 |
Sp-Adenosine-5'-O-(1-thiodiphosphate) sodium
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Sp-ADP-α-S |
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Sp-Adenosine-5’-O-(1-thiodiphosphate) (Sp-ADP-α-S), an isomer of the sulfur-containing nucleotide derivative ADP-α-S, functions as an inhibitor of phosphorylase kinase with an inhibition constant (Ki) of 0.53 µM. This co... |
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T83805 |
Rp-Adenosine-5'-O-(1-thiodiphosphate) sodium
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Rp-ADP-α-S |
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Rp-Adenosine-5'-O-(1-thiodiphosphate) (Rp-ADP-α-S), a sulfur-containing isomer of the nucleotide derivative ADP-α-S, acts as an inhibitor of phosphorylase kinase with an inhibition constant (Ki) of 0.53 µM. This compound... |
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T68581 |
AP23464
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AP23464 is a potent adenosine 5'-triphosphate (ATP)-based inhibitor of Src and Abl kinases, displays antiproliferative activity against a human CML cell line and Bcr-Abl-transduced Ba/F3 cells (IC(50) = 14 nM. AP23464 ab... |
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T36679 |
Rp-cAMPS sodium salt
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Rp-cAMPS sodium salt, a cAMP analog, is a potent, competitive cAMP-induced activation of cAMP-dependent PKA I and II (Kis of 12.5 μM and 4.5 μM, respectively) antagonist. Rp-cAMPS sodium salt is resistant to hydrolysis b... |
