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T9353 |
OXOMEMAZINE
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AChR
,
Histamine Receptor
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Oxomemazine is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic activity. Oxomemazine is a selective antagonist of mycotoxins M1 receptors, showing high (Ki=84 nM, M1 receptors) and low ... |
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T9519 |
Eliapixant
|
BAY 1817080 |
P2X Receptor
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Eliapixant (BAY 1817080) (BAY 1817080) is a potent and selective P2X3 receptor antagonist, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough. |
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T0828 |
Bromhexine hydrochloride
|
Bromhexine HCl,Auxit,Bisolvon |
SARS-CoV
,
HIV Protease
,
Autophagy
|
|
Bromhexine hydrochloride (Bisolvon) is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus. |
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T5099 |
Gefapixant
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RO 4926219,AF219,MK-7264 |
P2X Receptor
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Gefapixant (AF219) is a P2X3 receptor (P2X3R) antagonist with IC50 of ~30 nM at recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. |
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T3267 |
Potassium guaiacolsulfonate hemihydrate
|
Potassium guaiacolsulfonate,Potassium 4-guaiacolsulfonate hemihydrate |
Antibacterial
,
Antibiotic
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Potassium guaiacolsulfonate hemihydrate (Potassium guaiacolsulfonate) is an aromatic sulfonic acid used in medicine as an expectorant. |
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T5007 |
Benproperine phosphate
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Blascorid,Pirexyl phosphate |
Others
,
Microtubule Associated
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Benproperine phosphate (Pirexyl phosphate) is a cough suppressant. |
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T0768 |
Oxolamine citrate
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AF-438 citrate,SKF-9976 citrate |
Others
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Oxolamine citrate (AF-438 citrate) is a cough suppressant that is able to be used as a generic drug in many jurisdictions. |
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T8333 |
Aurintricarboxylic acid
|
ATA,NSC-4056,NSC4056,NSC 4056 |
Apoptosis
,
P2X Receptor
,
Influenza Virus
,
Topoisomerase
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Aurintricarboxylic acid (NSC-4056) is a strong inhibitor of topoisomerases and other nucleases. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. |
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T0284 |
Sulfogaiacol
|
guaiacolsulfonate |
Others
,
Antibacterial
|
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Sulfogaiacol (guaiacolsulfonate) is an antitussive agent, used for acute respiratory tract infections and cough. |
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T12489L |
Pimethixene maleate
|
Pimetixene maleate |
Dopamine Receptor
,
5-HT Receptor
,
AChR
,
Histamine Receptor
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Pimethixene maleate (Pimetixene maleate) is a potent 5-HT2B receptor antagonist with sedative and antitussive activity.Pimethixene maleate inhibits 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as we... |
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T0452 |
Dropropizine
|
(±)-Dropropizine,UCB-196,UCB-1967 |
Others
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Dropropizine (UCB-1967), a racemic non-opiate antitussive agent, is served as a cough suppressant. |
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T0464 |
Carbetapentane citrate
|
Pentoxyverine citrate |
AChR
|
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Carbetapentane citrate (Pentoxyverine citrate) , an antitussive (cough suppressant), is frequently used for a cough related to illnesses like the common cold. |
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T0217L |
(+)-Dropropizine
|
(+)-Dropropizine |
Histamine Receptor
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(+)-Dropropizine can inhibit histamine receptor, anti-allergic, and reduce a cough by modulation of neuropeptides involved in the cough reflex and by interfering with stimulus activation of peripheral endings of sensory ... |
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T0576 |
Diethylaminoethoxyethanol
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Others
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|
Diethylaminoethoxyethanol is served in the production of cough medicine Toclase and so on. |
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T28728 |
SCH-486757
|
SCH 486757,SCH486757 |
Opioid Receptor
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SCH-486757 is an agonist of nociceptin-1 (NOP1) and orphanin FQ peptide receptors and is used in the study of cough. |
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T0056 |
Oxeladin citrate
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|
Others
|
|
Oxeladin citrate is a highly potent and effective cough suppressant, which can treat all types of cough of various etiologies. It is not related to opium or its derivatives, so treatment with oxeladin is no risk of add... |
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T6660 |
SB-705498
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TRP/TRPV Channel
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SB705498 is a TRPV1 antagonist for hTRPV1. SB-705498 has been investigated for the treatment of Rhinitis, Chronic Cough, and Non-allergic Rhinitis. |
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T1229 |
Erdosteine
|
RV 144,KW-9144 |
NF-κB
,
Antibacterial
,
Adenosine deaminase
|
|
Erdosteine (RV 144) is a homocysteine-derived thiol derivative with mucolytic and free radical scavenging properties. Erdosteine and its metabolites modulate mucus production and viscosity, by which facilitating mucocili... |
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T64394 |
GW 833972A
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Cannabinoid Receptor
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GW 833972A is a selective CB2 receptor agonist.GW 833972A has an inhibitory effect on induced neural depolarization and on citric acid-induced cough in an animal model. |
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T67885 |
Camlipixant
|
BLU-5937 |
P2X Receptor
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|
Camlipixant (BLU-5937) is an orally active purine P2X3 receptor antagonist that is potent, selective and competitive. camlipixant has an IC50 of 25 nM for the hP2X3 homotrimer. camlipixant can be used for the treatment o... |
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T19644 |
Benzonatate
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Sodium Channel
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Benzonatate is an antagonist of sodium channel protein. |
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T34672 |
Sodium dibunate
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L1633,Dibunato di sodio,L 1633,Becantex,L-1633 |
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Sodium dibunate is a type of cough suppressant. |
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T34068 |
Pipazethate
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Pipazetatum,Lenopect,pipazethate monohydrochloride,Theratuss,Pipazetate |
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Pipipyrazine is a nonnarcotic oral cough suppressant, cough suppressant. |
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T32739 |
Libexin
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Lomapect,Toparten,HK 256,HK-256,Prenoxdiazine hydrochloride,HK256 |
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Libexin is a cough suppressant. |
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T20056 |
Oxolamine
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BRN 0527181,Bredon,AF-438,Ossolamina,AF 438 |
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|
Oxolamine is an agent of a cough suppressant. |
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T29880 |
Alloclamide hydrochloride
|
Alloclamide HCl,Hexacol |
|
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Alloclamide hydrochloride is a cough suppressant. |
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T3609 |
Dioxopromethazine
|
Prothanon,Dioxoprothazine |
Others
|
|
Dioxopromethazine (Dioxoprothazine) is a drug for the treatment of a cough and expectoration. It also can be used in local anesthesia. |
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T21372 |
Chlophedianol Hydrochloride
|
clofedanol hydrochloride,clofedanol,chlophedianol |
|
|
Chlophedianol hydrochloride, a centrally acting cough suppressant, is used in the treatment of dry cough. It has antihistamine and local anesthetic properties, and may have anticholinergic effects at high doses. |
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T81457 |
Piperidione
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|
|
|
Piperidione is a cough-suppressing agent [1]. |
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T16406 |
Orvepitant maleate
|
GW823296 maleate |
Neurokinin receptor
|
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Orvepitant maleate is an effective, selective, and well-tolerated neurokinin-1 receptor (NK-1) antagonist (pKi: 10.2 for human neurokinin-1 receptor). Orvepitant maleate has the potential for depressive disorder and chro... |
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T0768L |
Oxolamine hydrochloride
|
Oxolamine HCl,683 M hydrochloride,AF 438 hydrochloride |
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Oxolamine hydrochloride is a cough suppressant which may be useful in the treatment of pediatric asthma. |
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T26924 |
Butamirate
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Butamirate is a cough suppressant, it works by acting centrally through the receptors in the brainstem. |
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T25189 |
Butopiprine
|
Butopiprinum |
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Butopiprine is a cough suppressant with antispasmodic, local anesthetic and antitussive activity. |
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T68723 |
FPL-59257
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|
|
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FPL-59257 is a leukotriene antagonist that has been shown to abolish cough response & partly inhibit bronchoconstriction produced by leukotrienes C & D. |
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T25543 |
Isoaminile citrate
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|
|
Isoaminile citrate is a safe and effective central cough suppressant. In animal studies, it was as effective as codeine without any respiratory depression. |
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T60393 |
Clobutinol
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|
|
|
Clobutinol has anti-tussive effects. Clobutinol affects heart rate and blood pressure, it can be used for cough related research [1] [2] [3]. |
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T62422 |
Nav1.8-IN-2
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|
|
|
Nav1.8-IN-2 (compound 35A) is a potent inhibitor of Nav1.8 (IC50: 0.4 nM). Nav1.8-IN-2 can be used in studies of pain disorders, cough, acute and chronic pruritus. |
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T78523 |
Clobutinol hydrochloride
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|
Potassium Channel
|
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Clobutinol hydrochloride, an antitussive agent, influences heart rate and blood pressure, and is utilized in cough-related research [1] [2] [3]. |
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T60473 |
Nepinalone
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|
|
|
Nepinalone is an alchilaminate derivative of β-tetralone. Nepinalone is an orally active cough suppressant that possesses a non-opioid antitussive activity [1]. |
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T27158L |
DF-1012 FA
|
DF-1012 FA（163220-65-3 Free base） |
Neuropeptide Y Receptor
|
|
DF-1012 FA is a structural analog of DF-1012, a neuropeptide inhibitor used in the study of asthma and cough. |
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T68904 |
GW-833972A free base
|
|
|
|
GW833972 is a CB2 Agonist. GW 833972A inhibited capsaicin-induced depolarization of the human and guinea-pig and prostaglandin E(2) (PGE(2)) and hypertonic saline-induced depolarization of the guinea-pig isolated vagus n... |
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T63846 |
Gefapixant citrate
|
|
|
|
Gefapixant citrate is an orally active P2X3 receptor (P2X3R) antagonist that acts on human homologous recombinant hP2X3 (IC50: ~30 nM) and hP2X2/3 (IC50: 100-200 nM). gefapixant citrate can be used to study chronic cough... |
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T71141 |
Fenspiride-d5
|
|
|
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Fenspiride-d5 is intended for use as an internal standard for the quantification of fenspiride by GC- or LC-MS. Fenspiride is an antagonist of histamine H1 receptors and a non-steroidal anti-inflammatory drug (NSAID). It... |
