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Search Results for " factor-kB "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T39924	NF-κΒ activator 2		NF-κB
	NF-κΒ Activator 2 is a potent, orally active compound that efficiently activates NF-κB with an EC50 value of 1.58 μM. By enhancing NF-κB expression and activation, it induces SOD 2 synthesis, rendering it useful for amyo...		NF-κB
T0947	Dexamethasone acetate	Dexamethasone 21-acetate,Dexamethason acetate,NSC 39471	Glucocorticoid Receptor , Mitophagy , IL Receptor , Annexin A , NOS , Antibacterial , Autophagy
	Dexamethasone acetate (NSC 39471) is the acetate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexa...
T63107	Anti-inflammatory agent 6
	Anti-inflammatory agent 6 exhibits anti-inflammatory potential by blocking the phosphorylation of Iκb kinase α/β (IKKα/β), IκBα and nuclear factor kB p65 (NF-κb p65), which are key controllers of inflammation.

Compounds

Dexamethasone acetate

T0947

Synonym: Dexamethasone 21-acetate,Dexamethason acetate,NSC 39471

Target: Glucocorticoid Receptor, Mitophagy, IL Receptor, Annexin A, NOS, Antibacterial, Autophagy

Anti-inflammatory agent 6

T63107

Synonym:

Target:

カタログ番号	製品名	別名	ターゲット
T5660	Menthone		IL Receptor , TNF , NF-κB , Parasite
	Menthone has anti-inflammary activity,, it can suppress the lipopolysaccharide (LPS)-induced proinflammatory cytokines, interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha),as well as nuclear factor k...		IL Receptor , TNF , NF-κB , Parasite
T2745	18α-Glycyrrhetinic acid	Enoxolone,Glycyrrhetinic acid	Apoptosis , NF-κB , Proteasome
	18α-Glycyrrhetinic acid (Enoxolone) is an inhibitor of NF-kB and an activator of the proteasome, and functions as a longevity-promoting and anti-aggregation factor in multicellular organisms. It induces apoptosis.		Apoptosis , NF-κB , Proteasome
TN1874	Liriodendrin		ATPase , Potassium Channel , Prostaglandin Receptor
	Liriodendrin regulates lung inflammation, the phosphorylation of the NF-kB (p65) and expression of vascular endothelial growth factor (VEGF). Liriodendrin has anti-inflammatory, antinociceptive, hypoglycemic activities a...		ATPase , Potassium Channel , Prostaglandin Receptor
T37008	Reveromycin A
	Reveromycin A is the major component of a complex of spiroketal antibiotics isolated from Streptomyces sp. It inhibits the mitogenic activity of epidermal growth factor in Balb/MK cells (IC50 = 0.7 μg/ml), displays antip...

天然物製品

Menthone

T5660

Synonym:

Target: IL Receptor, TNF, NF-κB, Parasite

18α-Glycyrrhetinic acid

T2745

Synonym: Enoxolone,Glycyrrhetinic acid

Target: Apoptosis, NF-κB, Proteasome

Liriodendrin

TN1874

Synonym:

Target: ATPase, Potassium Channel, Prostaglandin Receptor

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-00674	RANK/TNFRSF11A Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Receptor activator of NF-κB(RANK,TNFRSF11A) belongs to one member of tumor necrosis factor receptor family.It is a receptor for TNFSF11/RANKL/TRANCE/OPGL. This gene encodes a type 1 membrane protein with a 30 amino acid...
TMPJ-00349	RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)	Human	HEK293 Cells
	Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANK...
TMPY-01710	IkB alpha/NFKBIA Protein, Human, Recombinant (His)	Human	E. coli
	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (IkB alpha, NFKBIA, or IKBA), is a member of the NF-kappa-B inhibitor family that function to inhibit the NF-kB transcription factor. NF...
TMPY-02757	TWEAKR/TNFRSF12A Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Fn14 (tumor necrosis factor receptor superfamily, member 12A), also known as TNFRSF12A, is the receptor for TNFSF12/TWEAK. Fn14 shares 82% amino acid identity with the mouse sequence. It contains a signal peptide, an ext...
TMPH-02173	TRBC2 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPH-02169	TRBC1 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPH-02168	TRAC Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Constant region of T cell receptor (TR) alpha chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize p...

RANK/TNFRSF11A Protein, Mouse, Recombinant (His)

TMPJ-00674

Species: Mouse

Expression System: HEK293 Cells

RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)

TMPJ-00349

Species: Human

Expression System: HEK293 Cells

IkB alpha/NFKBIA Protein, Human, Recombinant (His)

TMPY-01710

Species: Human

Expression System: E. coli

TWEAKR/TNFRSF12A Protein, Human, Recombinant (hFc)

TMPY-02757

Species: Human

Expression System: HEK293 Cells

TRBC2 Protein, Human, Recombinant (His & Myc)

TMPH-02173

Species: Human

Expression System: E. coli

TRBC1 Protein, Human, Recombinant (His)

TMPH-02169

Species: Human

Expression System: P. pastoris (Yeast)

TRAC Protein, Human, Recombinant (E. coli, His)

TMPH-02168

Species: Human

Expression System: E. coli

カタログ番号	製品名
L3800	NF-κB Signaling Compound Library		729 compounds
	A unique collection of 729 compounds targeting NF-κB signaling for high throughput screening and high content screening;

ライブラリー

NF-κB Signaling Compound Library

L3800

Compounds: 729