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ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T7144	BTS	N-Tosylbenzylamine,N-Benzyl-p-toluenesulfonamide	ATPase , Myosin
	BTS (N-Tosylbenzylamine) is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 : 5 μM) .		ATPase , Myosin
T23401	Strontium chloride		Others , CaSR
	Strontium chloride is an agonist of Calcium sensing receptor (CaSR) and directly affects C-type nerve fibers.		Others , CaSR
T0924	Benzocaine		Others , MRP , Sodium Channel
	Benzocaine is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.		Others , MRP , Sodium Channel
T7218	Endomorphin 2		Opioid Receptor
	Endomorphins-2 (EM-2) could decrease both the frequency and amplitude of the sEPSC of the motoneurons in lamina IX, which was reversed by the MOR antagonist CTOP. EM-2-IR fibers originated from primary afferent fibers f...		Opioid Receptor
TD0098	Direct Red 80	Sirius Red,Sirius Red F 3BA,C.I. direct red 80	Others
	Direct Red 80 (Sirius Red) is a tetra azo dye. It can be used to detect amyloid and can magnify the usual birefringence of collagen fibers in tissue sections.		Others
T30249	AZD 7009	AZD-7009,AZD7009	Sodium Channel
	AZD 7009 is a novel antiarrhythmic compound that inhibits the sodium current of hNav1.5 in CHO K1 cells with an IC50 of 11 uM. AZD 7009 inhibited late sodium current in isolated rabbit atrial and ventricular myocytes, an...		Sodium Channel
T0866	Propafenone	Rythmol,Propafenonum	Potassium Channel , MRP , Sodium Channel
	Propafenone (Propafenonum) is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity....		Potassium Channel , MRP , Sodium Channel
TP1325L	Gastrin-Releasing Peptide, human(TFA)		Others
	Gastrin-Releasing Peptide, human(TFA) is a regulatory human peptide that elicits gastrin release and regulates gastric acid secretion and enteric motor function. The post-ganglionic fibers of the vagus nerve that innerva...		Others
T71356	Lanperisone HCl
	Lanperisone, also known as NK433, is a muscle relaxant. NK433 inhibited the facilitation of the flexor reflex mediated by group II afferent fibers that was induced by intrathecal administration of noradrenaline-HCl. NK43...
T1046	Mexiletine hydrochloride	KOE-1173 (hydrochloride),Mexiletine HCl,KO1173	AhR , Sodium Channel
	Mexiletine hydrochloride (KOE-1173 hydrochloride) is a voltage-gated sodium channel blocker and a Class IB antiarrhythmic drug. Mexiletine hydrochloride exerts antiarrhythmic effects by inhibiting sodium current in myoca...		AhR , Sodium Channel
T0210L	Tamsulosin	LY253351 free base,HSDB7744,(R)-(-)-YM12617 free base,Harnal-D,Flowmax,HSDB 7744,HSDB-7744	Adrenergic Receptor
	Tamsulosin ((R)-(-)-YM12617 free base) is an alpha1A adrenergic receptor antagonist for the symptomatic treatment of benign prostatic hyperplasia (BPH). Tamsulosin is used to treat difficulty urinating, a common symptom ...		Adrenergic Receptor
T77577	SLU-PP-332		Estrogen/progestogen Receptor
	SLU-PP-332 is a pan-estrogen receptor-related receptor (ERR) agonist with high affinity for ERRα, ERRβ, and ERRγ with EC50 values of 98, 230, and 430 nM, respectively.SLUPP-332 enhances mitochondrial function and cellula...		Estrogen/progestogen Receptor
T20032	CI Direct Brown 2	Airedale Brown MD,Brown M,NSC 74701,Direct Brown 2,NSC-74701,NSC74701
	CI Direct Brown 2 is a direct dye. It is soluble in water and ionizable to form colored anions. It also can directly dye cellulose fibers or protein fibers.
T32724	LF 14	LF14,LF-14
	LF 14 affects mammalian non-myelinated nerve fibers.
T6782	Benzocaine hydrochloride	Benzocaine HCl,Ethyl p-aminobenzoate hydrochloride,Ethyl 4-aminobenzoate hydrochloride	Sodium Channel
	Benzocaine hydrochloride (Ethyl 4-aminobenzoate hydrochloride) is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.		Sodium Channel
T61215	Alinidine hydrobromide
	Alinidine hydrobromide, a specific bradycardic agent, diminishes the slope of the diastolic depolarization in sinoatrial tissue and Purkinje fibers [1].
T70282	Drofenine
	Drofenin is an anticonvulsant. It is an anticholinergic that acts both at the level of the nerves and the muscle fibers (neurotropic musculotropic effect). Drofenin also acts as FIASMA (functional inhibitor of acid sphin...
T71531	Metamizil hydrochloride
	Metamizil hydrochloride is a cholinolytic agent -- an agent that blocks the transmission of excitation from cholinergic nerve fibers -- and an antagonist of the mediator acetylcholine.
T26821	BIPM
	BIPM is a potent inhibitor of Rho-associated protein kinase 2 (ROCK2). Exposure of SH-SY5Y cells to BIPM led to significant changes in cell migration, actin stress fibers and neurite length. BIPM significantly inhibits p...
TP1668	CGGRGD TFA (1260223-44-6 free base)	CGGRGD TFA
	CGGRGD TFA is synthesized via solid-phase peptide synthesis technique and the surface of PCL fibers is aminolysised by amino 2-cyanobenzothiazole followed by the addition of 2-cyanobenzothiazole (CBT)[1].
TP1609	Angiotensin II (1-4), human
	Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure. Angiotensin also potentiates the release of norepinephrine by a direct action on po...
TP1325	Gastrin-Releasing Peptide, human
	Gastrin-Releasing Peptide, human is a regulatory human peptide that elicits gastrin release and regulates gastric acid secretion and enteric motor function. The post-ganglionic fibers of the vagus nerve that innervate th...
T35755	Avermectin B1a aglycone
	Avermectin B1a aglycone is an aglycone form of the anthelmintic and insecticide avermectin B1a . It hyperpolarizes P. crassipes muscle fibers with a minimum active concentration (MAC) value of 0.1 μM. Avermectin B1a agly...
T81787	MitTx-beta
	MitTx-beta, a peptide isolated from the venom of the Texas coral snake (Micrurus tener tener), forms a complex with MitTx-α to comprise MitTx, which exhibits ASIC1 channel activating activity on capsaicin-sensitive nerve...
T36561	(3S)-hydroxy Quinidine
	(3S)-hydroxy Quinidine is an active quinidine metabolite. Quinidine, an antiarrhythmic agent, undergoes rapid first-pass metabolism by the cytochrome P450 (CYP) isoforms CYP3A4, CYP2C9, CYP2E1, and CYP3A5, with CYP3A4 be...
T76135	Hemicellulase
	Hemicellulase, a member of the glycoside hydrolase enzyme family, plays a pivotal role in the degradation of plant biomass and carbon flow in nature. It facilitates the breakdown of glucose and polymer bonds within plant...
T61475	Ropivacaine mesylate
	Ropivacaine mesylate, a long-acting amide local anaesthetic, is used for spinal block and effectively mitigates neuropathic pain. It achieves analgesia by reversibly inhibiting sodium ion influx in nerve fibers, thus blo...
T71119	Netarsudil free base
	Netarsudil, also known as AR-11324, is a Rho-associated protein kinase inhibitor. Netarsudil is potential useful for treating glaucoma and/or reducing intraocular pressure. Netarsudil Increases Outflow Facility in Hum...

Compounds

BTS

T7144

Synonym: N-Tosylbenzylamine,N-Benzyl-p-toluenesulfonamide

Target: ATPase, Myosin

Target: Others, MRP, Sodium Channel

Endomorphin 2

T7218

Synonym:

Target: Opioid Receptor

Direct Red 80

TD0098

Synonym: Sirius Red,Sirius Red F 3BA,C.I. direct red 80

Target: Others

AZD 7009

T30249

Synonym: AZD-7009,AZD7009

Target: Sodium Channel

Propafenone

T0866

Synonym: Rythmol,Propafenonum

Target: Potassium Channel, MRP, Sodium Channel

Gastrin-Releasing Peptide, human(TFA)

Mexiletine hydrochloride

T1046

Synonym: KOE-1173 (hydrochloride),Mexiletine HCl,KO1173

Target: AhR, Sodium Channel

Tamsulosin

T0210L

Synonym: LY253351 free base,HSDB7744,(R)-(-)-YM12617 free base,Harnal-D,Flowmax,HSDB 7744,HSDB-7744

Target: Adrenergic Receptor

SLU-PP-332

T77577

Synonym:

Target: Estrogen/progestogen Receptor

CI Direct Brown 2

T20032

Synonym: Airedale Brown MD,Brown M,NSC 74701,Direct Brown 2,NSC-74701,NSC74701

Benzocaine hydrochloride

T6782

Synonym: Benzocaine HCl,Ethyl p-aminobenzoate hydrochloride,Ethyl 4-aminobenzoate hydrochloride

Target: Sodium Channel

Alinidine hydrobromide

Metamizil hydrochloride

CGGRGD TFA (1260223-44-6 free base)

TP1668

Synonym: CGGRGD TFA

Target:

Angiotensin II (1-4), human

TP1609

Synonym:

Target:

Gastrin-Releasing Peptide, human

TP1325

Synonym:

Target:

Avermectin B1a aglycone

(3S)-hydroxy Quinidine

カタログ番号	製品名	別名	ターゲット
T20386	Caprolactam		Others
	Caprolactam is a natural product used in the manufacture of synthetic fibers of the polyamide type.		Others
T15716	Lasalocid sodium	Ionophore X-537A sodium,Antibiotic X-537A sodium,Lasalocid-A sodium	Antibacterial , Antibiotic , Autophagy
	Lasalocid sodium (Lasalocid-A sodium) is a cationic ionophore antibiotic obtained from Streptomyces lasaliensis that, among other effects, dissociates the calcium fluxes in muscle fibers. Lasalocid sodium is used as a co...		Antibacterial , Antibiotic , Autophagy
T8195	Lotusine		Others
	Lotusine is a pure alkaloid extracted from the Nelumbo nucifera Gaertn. It shows effects on the action potentials in the myocardium and slow inward current in cardiac Purkinje fibers.		Others
TN1216	2-O-Acetyl-20-hydroxyecdysone	20-Hydroxyeedysone 2-acetate	Beta Amyloid , Others
	2-O-Acetyl-20-hydroxyecdysone is an ecdysone present in insects and terrestrial plants. 2-O-Acetyl-20-hydroxyecdysone inhibits amyloid-β42-induced cytotoxicity and is able to reduce the formation of Aβ oligomers by promo...		Beta Amyloid , Others
T3229	Cytochalasin D		ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
	Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertilization processes such as sperm penetration or sperm head dec...		ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
T2163	Dihydrocapsaicin	CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide	Others , TRP/TRPV Channel
	Dihydrocapsaicin (CCRIS1589) is isolated from Capsicum fruit. Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Like capsaicin, dihydrocapsaicin is an...		Others , TRP/TRPV Channel
T20173	Noradrenaline tartrate	NSC 169106,NSC-169106,l-Noradrenaline d-bitartrate,NSC169106,Norepinephrine bitartrate
	Norepinephrine bitartrate is a precursor of epinephrine. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceru...
T3S0626	Denudatine		Others
	1. Denudatine has effects on action potential of ventricular fibers and has inhibition on arrhythmogenic action of aconitine.		Others
T78489	Lotusine hydroxide
	Lotusine (hydroxide), a pure alkaloid isolated from the green seed embryos of Nelumbo nucifera Gaertn, influences action potentials in myocardial tissue and the slow inward current in cardiac Purkinje fibers [1].

天然物製品

Synonym: Ionophore X-537A sodium,Antibiotic X-537A sodium,Lasalocid-A sodium

Target: Antibacterial, Antibiotic, Autophagy

2-O-Acetyl-20-hydroxyecdysone

TN1216

Synonym: 20-Hydroxyeedysone 2-acetate

Target: Beta Amyloid, Others

Cytochalasin D

T3229

Synonym:

Target: ATPase, p38 MAPK, Calcium Channel, Akt, PI3K

Dihydrocapsaicin

T2163

Synonym: CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide

Target: Others, TRP/TRPV Channel

Noradrenaline tartrate

T20173

Synonym: NSC 169106,NSC-169106,l-Noradrenaline d-bitartrate,NSC169106,Norepinephrine bitartrate

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-00021	PADI4 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Protein-arginine deiminase type-4, also known as HL-6 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type I V and PADI4, is a cytoplasm and nucleus protein that belongs to the protein arginine deiminase f...
TMPH-00527	Fibritin Protein, Enterobacteria phage T4, Recombinant (His & SUMO)	Enterobacteria phage T4	E. coli
	Chaperone involved in tail fiber assembly and retraction. Acts as a chaperone helping to attach the long tail fibers to the virus during the assembly process. During phage assembly, twelve fibritin molecules attach to th...
TMPY-03809	COL5A2 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	COL5A2 is a component of type V collagen. It is known as the pro-alpha2(V) chain. COL5A2, together with two pro-alpha1(V) chains can form type V procollagen. These triple-stranded, rope-like procollagen molecules arrange...
TMPH-01477	HIST1H1D Protein, Human, Recombinant (His & MBP)	Human	E. coli
	Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structur...
TMPH-00175	YuaB Protein, Bacillus subtilis, Recombinant (His & SUMO)	Bacillus subtilis	E. coli
	Involved in biofilm formation. Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm. The layer is stable and capable of resistance to high mechanical force compression....
TMPY-04126	MUSTN1 Protein, Human, Recombinant (His)	Human	E. coli
	MUSTN1 (Musculoskeletal, Embryonic Nuclear Protein 1) is a Protein Coding gene. It may play an important role in regulating musculoskeletal development in mammals. It belongs to the MUSTANG family. The MUSTN1 protein is ...
TMPY-01958	RhoA Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Transforming protein RhoA, also known as Rho cDNA clone 12, Ras homolog gene family member A, RHOA and ARH12, is a cell membrane and cytoplasm protein that belongs to the small GTPase superfamily and Rho family. The Rho ...
TMPY-02223	GSTM2 Protein, Human, Recombinant (His)	Human	E. coli
	Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2, and GSTM2, is a cytoplasm protein that belongs to the GST superfamily and Mu family. GSTM2 / GST4 contains one GST C-terminal domain and one GST N-te...
TMPY-03060	Parvin alpha/PARVA Protein, Human, Recombinant (GST)	Human	E. coli
	Actopaxin, also known as alpha-parvin, belongs to the parvin family. It is widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. Actopaxin contains 2 CH (calponin-homology) domains and probab...
TMPJ-01415	ANGPTL4 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Angiopoietin-related protein 4（ANGPTL4）is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migratio...
TMPJ-00869	GLB1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	β Galactosidase is a lysosomal β Galactosidase that hydrolyzes the terminal β Galactose from Ganglioside and Keratan sulfate. In lysosome, the mature β Galactosidase protein associates with Cathepsin A and Neuraminidase ...
TMPH-01213	DNASE1L3 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends. Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA...
TMPY-03052	MFAP5 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	MFAP5 (Microfibril Associated Protein 5, also known as MAGP2) is a Protein Coding gene. MFAP5 is a component of the elastin-associated microfibrils. It belongs to the MFAP family. As a 25-kD microfibril-associated glycop...
TMPH-01214	DNASE1L3 Protein, Human, Recombinant	Human	E. coli
	Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends. Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA...
TMPH-01212	DNASE1L3 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends. Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA...
TMPY-01695	CASPR2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	CNTNAP2/CASPR2 is a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor re...
TMPH-01502	Humanin Protein, Human, Recombinant (GST)	Human	E. coli
	Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective e...
TMPJ-01188	CORO6 Protein, Human, Recombinant (His)	Human	E. coli
	Coronin 6, a newly identified member of the coronin family, is highly enriched at adult NMJs and regulates AChR clustering via modulating the interaction between receptors and the actin cytoskeletal network. Coronins are...
TMPH-01503	Humanin Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective e...
TMPH-02690	PLA2G10 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids with preference for phosphatid...