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T22465 |
1,2-Distearoyl-sn-glycerol
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Others
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1,2-Distearoyl-sn-glycerol is an internal standard for the isolation and characterization of molecular species of 1,2-diacyl-sn-glycerol (DAG). |
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T41046 |
Biotin-azide
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N-(3-Azidopropyl)biotinamide,Biotin-azide |
Others
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Biotin-azide (N-(3-Azidopropyl)biotinamide) is a biotin that is used in the preparation of various biotin affixes and in the identification of proteins. |
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T124698 |
4-O-p-Coumaroylquinic acid
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4-o-Coumaroylquinic acid,4-O-pCoQA |
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4-O-p-Coumaroylquinic acid (4-O-pCoQA) is a hydroxycinnamic acid extracted from the skin and pulp of papaya, which can be used as a biomarker for the identification of biomarkers associated with rose apple aphid resistan... |
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T19084 |
1-Naphthyl acetate
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AChE
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1-Naphthyl acetate is usually used in a rapid staining method for identification of macrophages. 1-Naphthyl acetate is a potent chromogenic substrate for the detection of erythrocyte acetylcholinesterase (AChE) activity.... |
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T15598 |
Isosulfan blue
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Others
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Isosulfan blue is a blue dye for the identification of lymph vessels during lymphangiography. Isosulfan blue is used during sentinel lymph node biopsies in breast cancer. However, Isosulfan blue may be a cause of allergi... |
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T0312 |
Toluidine Blue
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Blutene chloride |
Others
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Toluidine Blue (Blutene chloride), a phenothiazine, is used as a biological stain, a hemostatic, and a dye for silk and wool. Blutene chloride is also used as a diagnostic aid for gastric neoplasms and oral, and used in ... |
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T38238 |
2'-Deoxy-2'-fluorocytidine
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Nucleoside Antimetabolite/Analog
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Influenza Virus
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2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine can act synergistically with T705 to increase the potency o... |
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T38361 |
GSK717
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IL Receptor
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NOD
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GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, with an IC50 of 400 nM for MDP-stimulated IL-8 secretio... |
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T30307 |
BCN-E-BCN
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BCN-e-BCN is a new cell permeability probe for protein sulfonic acid identification. |
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T71873 |
Temechine hydrobromide
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Temechine hydrobromide is used for the identification of new diterpenoidal alkaloid leads as tyrosinase inhibitors. |
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T10956 |
Dansyl glutathione
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DNS-glutathione |
Others
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Dansyl glutathione is a capture agent used for quantitative assessment and identification of reactive metabolites. |
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T36224 |
N-Hippuryl-His-Leu (hydrate)
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N-Hippuryl-His-Leu (hydrate) is a synthetic substrate for angiotensin-converting enzyme (ACE) that has been used in the in vitro identification of ACE inhibitors., |
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T40616 |
8-Azido-ATP
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8-Azidoadenosine 5'-triphosphate,8-N3-ATP,8-Azido-ATP |
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8-Azido-ATP is a nucleotide analog that demonstrates photo-reactivity properties. It offers utility in the precise labeling and identification of proteins, particularly those involved in DNA-dependent RNA polymerase acti... |
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T33568 |
N-Acetylanonaine
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VLT043 |
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N-Acetylanonaine may be used as a substrate for the identification, differentiation, and characterization of aminoacylase(s)/amidohydrolase(s). |
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T12562 |
Protein kinase affinity probe 1
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Others
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Protein kinase affinity probe 1 is a protein kinase affinity probe for the functional identification of protein kinases (PKs). |
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T68962 |
Declenperone
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Declenperon acts as a reagent for antimalarial drug lead identification. The are also used in the chemical development of selective and specific serotonin S2-antagonists. |
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T37424 |
CAY10781
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CAY10781 |
Others
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CAY10781 is an inhibitor of the protein-protein interaction between neuropilin-1 (NRP-1) and VEGF-A.1It inhibits the interaction by 43% when used at a concentration of 12.5 μM. CAY10781 also inhibits VEGF-A-induced phosp... |
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T81488 |
PHI-27 (rat)
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PHI-27 (rat) is a peptide composed of 27 amino acids utilized for the identification of peptide hormones and other bioactive peptides [1]. |
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TP1502 |
MAGE-A3 (195-203)
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MAGE-A3 195-203 |
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This peptide MAGE-3-encoded HLA-A24 epitope is a high MHC binder.The identification of this MAGE-3/HLA-A24 peptide may as a result effectiveially offer the opportunities to design peptide-based immunotherapeutic approach... |
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T36128 |
Tolmetin β-D-Glucuronide
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Tolmetin β-D-Glucuronide has reactive properties with human serum albumin, allowing identification of the binding site and reaction mechanism by tandem mass spectrometry. |
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T81489 |
PHI-27 (porcine)
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PHI-27 (porcine) is a porcine-derived peptide consisting of 27 amino acids, utilized in the identification of peptide hormones and other bioactive peptides [1]. |
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T40837 |
7-Acetoxy-1-methylquinolinium iodide
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AMQI |
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7-Acetoxy-1-methylquinolinium iodide (AMQI) serves as a fluorogenic substrate for cholinesterase, with excitation (Ex) occurring at 320 nm and emission (Em) at 410 nm. In the fluorometric flow system, the hydrolysis of t... |
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T83753 |
RAD17-derived Peptide TFA
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RAD17-derived peptide, a substrate for the ataxia-telangiectasia and RAD3-related protein/kinase (ATR), facilitates the identification of ATR inhibitors. |
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T80657 |
SARS-CoV-2 3CLpro-IN-15
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Virus Protease
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SARS-CoV-2 3CLpro-IN-15 (compound a), a beta-nitrostyrene derivative, acts as an inhibitor of the SARS-CoV-2 3CL protease (3CLpro), effectively inhibiting viral replication and transcription. It is instrumental in the id... |
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T82006 |
JM3A
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JM3A, a highly specific peptoid reagent, selectively targets cell surface vimentin (CSV) on early lung cancer cells undergoing tumor transformation. By conjugating with fluorophores [1], JM3A detects and stains CSV, enab... |
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T78420 |
3-MeOARh-NTR
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3-MeOARh-NTR is an activatable imaging probe characterized by high selectivity and stability, offering a high signal-to-noise ratio specifically for nitroreductase (NTR) detection. It serves as an efficient molecular too... |
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T36031 |
Desmethyl Ofloxacin (hydrochloride)
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Desmethyl ofloxacin is a metabolite of the fluoroquinolone antibiotic ofloxacin .1
1.Sudo, K., Okazaki, O., Tsumura, M., et al.Isolation and identification of metabolites of ofloxacin in rats, dogs and monkeysXenobiotica... |
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T36743 |
CDK7/9 tide
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CDK7/9 tide is peptide substrate for CDK7 or CDK9[1].
[1]. Robert T, et, al. Development of a CDK10/CycM in vitro Kinase Screening Assay and Identification of First Small-Molecule Inhibitors. Front Chem. 2020 Feb 27; 8:1... |
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T70326 |
Mevidalen HBA
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Mevidalen, also known as LY3154207, is a novel, potent, and subtype selective human D1 positive allosteric modulator (PAM) with minimal allosteric agonist activity (EC50 = 3 nM). In contrast to orthosteric agonists, LY3... |
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T75377 |
Thymolphthalein monophosphate disodium hydrate
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Thymolphthalein monophosphate disodium hydrate serves as a chromogenic substrate for the detection of acid phosphatase and alkaline phosphatase. During the enzymatic reaction, thymolphthalein is liberated which elevates ... |
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T77767 |
GLF16
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GLF16 is a hydrophilic fluorescent SBB analog and robustly identifies senescence. It enables the use of flow cytometry and live cell sorting for rapid senescent cell detection. GLF16 is suitable for in vivo identificatio... |
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T81110 |
SQM-NBD
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SQM-NBD is a potent, selective AIE fluorescent probe with exceptional sensitivity to Cys and Hcy, exhibiting limits of detection (LOD) at 54 nM and 72 nM respectively. It demonstrates good cell permeability and low cytot... |
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T83813 |
8-Azidoadenosine-5'-O-diphosphate sodium
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8-azido-ADP,Click Tag™ 8-Azidoadenosine-5'-O-diphosphate |
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8-Azidoadenosine-5'-O-diphosphate (8-azido-ADP), a clickable variant of the ATP precursor and purinergic receptor ligand ADP, serves as a photoaffinity label for proteins including glutamate dehydrogenase (GDH) isoprotei... |
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T83671 |
CCP-biotin Peptide (non-cyclized)
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Citrullinated Filaggrin (Q447H, S449C, G459R, E460G, S462C) (R455) (447-467)-biotin Peptide (non-cyclized),Cyclic Citrullinated Peptide-biotin Peptide (non-cyclized) |
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CCP-biotin peptide (non-cyclized) is a linear, biotin-labeled derivative of the circular citrullinated peptide (CCP), mirroring the human filaggrin sequence from amino acids 447 to 467 with specific substitutions (Q447H,... |
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T36132 |
3β-OH-7-Oxocholenic Acid
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3β-OH-7-Oxocholenic acid is a bile acid.1 It is also a metabolite of 7β-hydroxy cholesterol in rats. Conjugated forms of 3β-OH-7-oxocholenic acid have been found in the urine of patients with Neimann-Pick disease type C.... |
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T41171 |
BODIPY FL VH032
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BODIPY FL VH032 is a high-affinity VHL fluorescent probe (Kd= 3.01 nM) with application in time-resolved fluorescence resonance energy-transfer (TR-FRET) assays for high-throughput identification and characterization of ... |
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T38382 |
8Br-HA
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8Br-HA is an inhibitor of fragile histidine triad diadenosine triphosphatase (FHIT; IC50= 0.12 μM).1It inhibits the growth of HCC827 and H460 lung cancer cells (GI50s = 0.87 and 5.9 μM, respectively).
1.Kawaguchi, M., Se... |
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T83722 |
FALGPA TFA
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2-Furanacryloyl-L-leucylglycyl-L-prolyl-L-alanine,2-Furanacryloyl-Leu-Gly-Pro-Ala-OH |
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FALGPA, a colorimetric substrate for collagenase, exhibits selectivity over trypsin, thermolysin, and elastase. It uniquely interacts with collagenase, which binds to and cleaves the Leu-Gly (LG) peptide sequence, releas... |
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T37704 |
Olanzapine Lactam Impurity
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Olanzapine lactam impurity is a potential impurity found in commercial preparations of olanzapine.1It is a degradation product formed by exposure to thermal or oxidative stress.
1.Baertschi, S.W., Brunner, H., Bunnell, C... |
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T37628 |
Ibuprofen impurity 1
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Ibuprofen impurity 1 is an Ibuprofen impurity. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1].
[1]. Noreen Y, et al. Development of a radiochemical c... |
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T35534 |
7-Methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-amine
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7-Methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-amine is a building block.1It has been used in the synthesis of PI3K inhibitors.
1.Scott, W.J., Hentemann, M.F., Rowley, R.B., et al.Discovery a... |
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T37804 |
8MDP
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Potent equilibrative nucleoside transporter 1 (ENT1) inhibitor (IC50 = 0.43 nM). Inhibits hENT1 and hENT2 uptake of [H3]uridine in K562 cells and K15NTD cells respectively.
Lin et al (2011) Design, synthesis, and evaluat... |
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T37823 |
M 084 hydrochloride
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TRPC4/5 channel blocker (IC50 values are 3.7-10.3 and 8.2 μM, respectively). Also weakly blocks TRPC3 channels. Exhibits rapid antidepressant and anxiolytic effects in vivo.
Zhu et al (2015) Identification and optimizati... |
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T37779 |
2,3,4,5-Tetrachlorophenol
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2,3,4,5-Tetrachlorophenol is a metabolite of the insecticide γ-lindane.1It is toxic to fathead minnows and rainbow trout (LC50s = 0.496 and 0.304 mg/L, respectively, in tank water).2
1.Chadwick, R.W., and Freal, J.J.The ... |
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T37528 |
TBPC
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Positive allosteric modulator of neuropeptide Y receptor 4 (Y4R). Potentiates Y4R response to pancreatic polypeptide (PP), neuropeptide Y (NPY) and peptide YY (PYY) (EC50 values are 0.03, 0.4 and 0.5 nM respectively). Sh... |
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T37131 |
MS 15203
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Potent and selective GPR171 partial agonist (EC50 = 90 nM; 28% inhibition of forskolin activated adenylyl cyclase activity in rat hypothalamic memebranes). Exhibits minimal binding to a panel of ~70 GPCRs and 10 other re... |
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T37321 |
RN-9893 (hydrochloride)
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RN-9893 is an antagonist of transient receptor potential vanilloid 4 (TRPV4; IC50s = 0.42 and 0.66 μM, respectively, for the human and rat receptors).1 It is selective for TRPV4 over TRPV1, TRPV3, and TRPM8 (IC50s = 10, ... |
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T36608 |
(±)8-HEPE
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(±)8-HEPE is produced by non-enzymatic oxidation of EPA. It contains equal amounts of 8(S)-HEPE and 8(R)-HEPE. The ability of (±)8-HEPE to induce hatching of E. modestus and B. balanoides eggs is probably due to the pres... |
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T36035 |
CAY10784
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CAY10784 is a STAT3 inhibitor (IC50= 0.74 μM in a reporter assay) and a derivative of WP1066 .1It inhibits proliferation of HeLa, Caco-2, A549, A375, U87MG, and HL-60 cancer cells (IC50s = 1.8, 1.8, 3, 2.8, 2.3, and 1.2 ... |
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T35485 |
6-Prenylindole
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6-Prenylindole is a bacterial metabolite that has been found in Streptomyces and has antifungal and antimalarial properties.1 It is active against A. brassicicola strain TP-F0423 and F. oxysporum f. sp. tulipae TU-4-2 (1... |
