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Search Results for " pigmented "

4

阻害剤

4

天然化合物

カタログ番号	製品名	別名	ターゲット
T20150	C.I. 37505	3-Hydroxy-2-naphthanilide,2-Naphthanilide, 3-hydroxy- (8CI)
	C.I. 37505 is an azo dye coupling component.It implicated in occupational pigmented contact dermatitis.
T76868	Lacnotuzumab
	Lacnotuzumab (MCS110), a humanized IgG1/κ monoclonal antibody, neutralizes and inhibits the interaction between CSF-1 and its receptor, CSF-1R. It is utilized in researching pigmented villonodular synovitis [1] [2].
T62730	TDRL-X80
	TDRL-X80 is a potent inhibitor of the pigmented dry skin protein (XPA). TDRL-X80 inhibits the DNA binding activity of XPA. TDRL-X80 acts on single, double and cisplatin damaged DNA with IC50 values of 18, 20 and 29 μM in...
T38048	Globotetraosylceramides (porcine RBC)
	Globotetraosylceramides are bioactive neutral glycosphingolipids. They are the major glycolipids in human erythrocytes. They act as receptors for the Shiga toxins Stx1, Stx2, and Stx2e, the cytotoxic protein pierisin-1, ...

Compounds

Synonym: 3-Hydroxy-2-naphthanilide,2-Naphthanilide, 3-hydroxy- (8CI)

Globotetraosylceramides (porcine RBC)

カタログ番号	製品名	別名	ターゲット
T0070	Pentoxifylline	Oxpentifylline,PTX,BL-191	HIV Protease , PDE , Adenosine Receptor , Autophagy
	Pentoxifylline (PTX) modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodiesterase and affects blood rheology. It also inhibits platelet ...		HIV Protease , PDE , Adenosine Receptor , Autophagy
T0543	7-Methylxanthine	Heteroxanthine,Heteroxanthin	Nucleoside Antimetabolite/Analog , Endogenous Metabolite
	7-Methylxanthine (Heteroxanthine), a methyl derivative of xanthine, is one of the purine components in urinary calculi. 7-Methylxanthine appears to prevent FDM in pigmented rabbits by remodeling the posterior sclera.		Nucleoside Antimetabolite/Analog , Endogenous Metabolite
T2P2806	Hederacolchiside A1	Raddeanoside R13	Apoptosis , ERK , MEK , Akt , PI3K , Parasite , mTOR
	Hederacolchiside A1 (Raddeanoside R13) shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering membrane integrity and potential. Hederacol...		Apoptosis , ERK , MEK , Akt , PI3K , Parasite , mTOR
TN4179	Haginin A		ERK , Tyrosinase , Akt
	Haginin A is an effective inhibitor of hyperpigmentation caused by UV irradiation or by pigmented skin disorders through downregulation via ERK and Akt/PKB activation, MITF, and also by the subsequent downregulation of t...		ERK , Tyrosinase , Akt

天然物製品

Synonym: Oxpentifylline,PTX,BL-191

Target: HIV Protease, PDE, Adenosine Receptor, Autophagy

7-Methylxanthine

Synonym: Heteroxanthine,Heteroxanthin

Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite

Hederacolchiside A1

Synonym: Raddeanoside R13

Target: Apoptosis, ERK, MEK, Akt, PI3K, Parasite, mTOR

Target: ERK, Tyrosinase, Akt

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