|
T8719 |
SC99
|
|
Apoptosis
,
JAK
,
STAT
|
|
SC99 is a selective inhibitor of JAK2-STAT3 activation. SC99 downregulates the expression of STAT3-modulated genes.SC99 inhibits platelet activation, aggregation and displays potent anti-myeloma, anti-thrombotic activiti... |
|
T25364L |
Efegatran sulfate
|
LY294468 sulfate,GYKI-14766 sulfate,LY 294468 sulfate,LY-294468 sulfate |
Thrombin
|
|
Efegatran sulfate (LY294468 sulfate) is a potent thrombin inhibitor used in the treatment of thrombotic disorders. |
|
T68092 |
Letaxaban
|
TAK-442 |
Factor Xa
|
|
Letaxaban (TAK-442) is a small molecule Xa factor inhibitor that can be used to study polar coronary syndromes and thrombotic blockages. |
|
T20765 |
Atorvastatin
|
|
HMG-CoA Reductase
,
Autophagy
|
|
Atorvastatin is an orally active HMG-CoA reductase inhibitor that has the ability to effectively lower blood lipids by activating liver cytochrome p450 to accelerate metabolism. Atorvastatin inhibited proliferation and i... |
|
T11659 |
Inogatran
|
H-314-27 |
Others
|
|
|
|
T40802 |
Poloxamer 188
|
|
|
|
Poloxamer 188, a nonionic linear copolymer possessing surfactant properties, demonstrates anti-thrombotic, anti-inflammatory, and cytoprotective activities across different tissue injury models. |
|
T70106 |
F-050
|
|
|
|
F-050 is a biochemical that has been shown to inhibit platelet aggregation induced by CaCl2, arachidonic acid, collagen, adenosine diphosphate (ADP) and thrombin in guinea pigs, rabbits and rats in vitro. F-050 may be us... |
|
T71429 |
O-Demethyl apixaban sulfate
|
|
|
|
O-Demethyl apixaban sulfate is a metabolite of Apixaban, a potent and highly selective factor Xa inhibitor. Apixaban is currently under development for treatment of arterial and venous thrombotic diseases. |
|
T62949 |
(1R,3S)-THCCA-Asn
|
|
|
|
(1R,3S)-THCCA-Asn (4j) is a selective inhibitor of thrombin (IC50: 0.07-0.14 μM) with anti-thrombotic effects. |
|
T71532 |
Fondaparinux free base
|
|
|
|
Fondaparinux Free Base is a synthetic pentasaccharide that mediates the interaction of HEPARIN with ANTITHROMBINS and inhibits FACTOR Xa; it is used for prevention of VENOUS THROMBOEMBOLISM after surgery. Fondaparinux is... |
|
T78666 |
Egaptivon pegol
|
ARC 1779 |
Integrin
|
|
Egaptivon pegol (ARC1779) is an aptamer that inhibits the interaction of von Willebrand Factor (VWF) with platelet GPIb receptors, exhibiting anti-thrombotic efficacy. |
|
T75689 |
Mumefural
|
|
|
|
Mumefural, a bioactive compound found in the processed fruit of Prunus mume Sieb., inhibits platelet aggregation, exhibits anti-thrombotic properties, and ameliorates cognitive impairment [1] [2]. |
|
T64257 |
FXIa-IN-8
|
|
|
|
FXIa-IN-8 is a potent and selective inhibitor of FXIa (IC50: 14.2 nM). FXIa-IN-8 exhibits anti-thrombotic effects and does not increase the risk of bleeding or significant toxicity sup>[1]. |
|
T75408 |
Batroxobin
|
|
|
|
Batroxobin (DF-521), a venom derived from the Bothrops atrox moojeni snake, facilitates thrombolysis, inhibits thrombus reformation, and offers neuroprotection. It holds research potential for treating cerebral venous th... |
|
T62507 |
Protease-Activated Receptor-1 antagonist 1
|
|
|
|
Protease-Activated Receptor-1 antagonist 1 (Compound 13) is a protease-activated receptor 1 (PAR-1) antagonist with an IC50 of 3 nM obtained by the FLIPR technique. antagonist 1 can be used to study thrombotic cardiovasc... |
|
T78283 |
Caplacizumab
|
ALX-0081,ALX-0681 |
|
|
Caplacizumab (ALX-0681), a humanized anti-von Willebrand factor (vWF) nanobody, serves to impede vWF-mediated platelet adhesion, thereby averting additional microthrombi formation. This compound is utilized in the study ... |
