Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Rosuvastatin (ZD 4522) is an antilipemic agent that competitively inhibits hydroxymethyl-glutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Rosuvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
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5 mg | 在庫あり | ¥ 10,500 | |||
10 mg | 在庫あり | ¥ 17,000 | |||
25 mg | 在庫あり | ¥ 29,000 | |||
50 mg | 在庫あり | ¥ 39,000 | |||
100 mg | 在庫あり | ¥ 64,000 | |||
200 mg | 在庫あり | ¥ 90,000 |
説明 | Rosuvastatin (ZD 4522) is an antilipemic agent that competitively inhibits hydroxymethyl-glutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Rosuvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. |
ターゲット&IC50 | HMG-CoA:11 nM |
別名 | ZD 4522 |
分子量 | 481.54 |
分子式 | C22H28FN3O6S |
CAS No. | 287714-41-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 199.4 mM
DMSO: 50 mg/mL (103.83 mM)
You can also refer to dose conversion for different animals. 詳細
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Rosuvastatin 287714-41-4 Autophagy Membrane transporter/Ion channel Metabolism Potassium Channel HMG-CoA Reductase Inhibitor HMG-CoA Reductase (HMGCR) repolarization KcsA cardiac durations triglycerides cholesterol action ZD 4522 low-density Hsp70 ZD4522 gene inhibit lipoprotein APDs hERG potential related QTc ZD-4522 inhibitor