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ターゲット

Calcium Channel Sodium Channel Carbonic Anhydrase

263

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天然化合物

リコンビナントタンパク質

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カタログ番号	製品名	別名	ターゲット
T0267	Zonisamide	AD 810,CI 912	Calcium Channel , Sodium Channel , Carbonic Anhydrase
	Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydrase although this is not one of the main mechanisms...		Calcium Channel , Sodium Channel , Carbonic Anhydrase
T15052	Dapansutrile		NOD-like Receptor (NLR) , NOD
	Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.		NOD-like Receptor (NLR) , NOD
T23351	Shz 1		Others
	induces phenotypic differentiation		Others
T2052	KY02111		Wnt/beta-catenin
	KY02111 facilitates differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, maybe affect downstream of GSK3β and APC.		Wnt/beta-catenin
T9258	Aficamten		Others
	Aficamten is a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy.		Others
T22341	GSK-114		Others
	GSK-114, a selective inhibitor of TNNI3 Interacting Kinase (TNNI3K) with IC50 of 25 nM, shows significant bias for TNNI3K over B-Raf with IC50 of 1000 nM, exceptional broad spectrum kinase selectivity and adequate oral e...		Others
T8786	VUT-MK142		Others
	VUT-MK142 is a new cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes,which may be useful to differentiate stem cells into cardiomyocytes for cardiac repair.		Others
T1787	Levobupivacaine		Sodium Channel
	Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AstraZ...		Sodium Channel
T11807	L002		Others , Histone Acetyltransferase , STAT
	L002, a potent, cell-permeable, reversible, and specific acetyltransferase p300 (KAT3B) inhibitor with an IC50 of 1.98 μM, directly binds the acetyl-CoA pocket and competitively inhibits the FATp300 catalytic domain. By ...		Others , Histone Acetyltransferase , STAT
T8391	Cesium chloride	CsCl	Potassium Channel
	Cesium chloride (CsCl) is considered to be the most toxic of the alkali chlorides, inhibiting fungal growth.		Potassium Channel
T24109	GSK329	GSK 329,GSK-329	Others
	GSK329 is an effective and selective inhibitor of TNNI3 Interacting Kinase (TNNI3K). GSK329 exhibits positive cardioprotective outcomes in the model of ischemia/reperfusion cardiac injury.		Others
T16686	Pyr10		TRP/TRPV Channel
	Pyr10 is a pyrazole derivative and a selective TRP cation 3 inhibitor. Pyr10 has the ability to distinguish between receptor-operated TRPC3 and native stromal interaction molecule 1 (STIM1)/Orai1 channels. Pyr10 inhibits...		TRP/TRPV Channel
T3144	BML-284	Wnt agonist 1	Wnt/beta-catenin
	BML-284 (Wnt agonist 1) is a potent, selective and , cell-permeable Wnt signaling activator.		Wnt/beta-catenin
T9232	Mitochondrial fusion promoter M1		Mitochondrial Metabolism
	Mitochondrial fusion promoter M1, a modulator of mitochondrial dynamics, enhances mitochondrial function and cellular respiration, and has shown efficacy in reducing brain and cardiac damage in rats suffering from cardia...		Mitochondrial Metabolism
T6086	Clopamide	Brinaldix,Adurix,Aquex	Sodium Channel
	Clopamide (Brinaldix) is a piperidine and sulfamoylbenzamide-based diuretic with thiazide-like diuretic activity.		Sodium Channel
T1449	Hydrochlorothiazide	HCTZ	Potassium Channel , Carbonic Anhydrase , TGF-beta/Smad
	Hydrochlorothiazide (HCTZ) is a Thiazide Diuretic. The physiologic effect of hydrochlorothiazide is by means of Increased Diuresis.		Potassium Channel , Carbonic Anhydrase , TGF-beta/Smad
T15050	Danicamtiv	MYK-491,SAR 440181	Myosin
	Danicamtiv (MYK-491) is an inotropic agent and it also is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and preserves mechanical efficiency.		Myosin
T21454	Nicardipine	Cardene,Dagan,Antagonil,Flusemide	Calcium Channel
	Nicardipine (Cardene), a calcium channel blockers belonging to the dihydropyridine class, is a drug used to treat angina and high blood pressure.		Calcium Channel
T12478L	Pinacidil	S 1230,P 1134,S-1230,P-1134,P1134	Potassium Channel
	Pinacidil (P 1134) is a guanidine that opens potassium channels and directly dilates peripheral blood vessels in small arteries, lowering blood pressure and peripheral resistance and producing fluid retention.		Potassium Channel
T14782	Brilaroxazine	RP5063	Dopamine Receptor , 5-HT Receptor
	Brilaroxazine (RP5063) is a potent multimodal dopamine/5-HT modulator. Brilaroxazine is a partial agonist of dopamine D2, D3, and D4 receptors, 5-HT1A (Ki =1.5 nM) and 5-HT2A (Ki = 2.5 nM), and has antagonist activity 5-...		Dopamine Receptor , 5-HT Receptor
T20898	(R)-Propranolol hydrochloride	Dexpropranolol hydrochloride,(R)-(+)-Propranolol	Adrenergic Receptor
	(R)-Propranolol hydrochloride (Dexpropranolol hydrochloride) is the less active enantiomer of the anti-adrenoceptor (β-adrenoceptor) antagonist propranolol. Propranolol is a nonselective β-adrenergic receptor (βAR) antag...		Adrenergic Receptor
T15418	GS-6201	CVT-6883	Adenosine Receptor
	GS-6201 (CVT-6883) is a selective antagonist of adenosine A2B receptor. GS-6201 shows high affinity and selectivity for the human adenosine A2B receptors with a Ki of 22 nM.		Adenosine Receptor
T15207	Eleclazine hydrochloride	GS 6615 hydrochloride	Sodium Channel
	Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).		Sodium Channel
T2176	2,3-Butanedione 2-Monoxime	Diacetyl monoxime,2,3-Butanedione-2-monoxime	Akt
	2,3-Butanedione 2-Monoxime (Diacetyl monoxime) is an inhibitor of skeletal and cardiac muscle contraction.		Akt
T1056	Isoprenaline hydrochloride	NCI-c55630,Isoproterenol hydrochloride,Isoprenaline HCl	PI3K , Endogenous Metabolite , Adrenergic Receptor , PDE
	Isoprenaline hydrochloride (NCI-c55630) is a potent beta-adrenergic agonist with the peripheral vasodilator, bronchodilator, and cardiac stimulating properties.		PI3K , Endogenous Metabolite , Adrenergic Receptor , PDE
T1676	Rosuvastatin	ZD 4522	Potassium Channel , HMG-CoA Reductase , Autophagy
	Rosuvastatin (ZD 4522) is an antilipemic agent that competitively inhibits hydroxymethyl-glutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting...		Potassium Channel , HMG-CoA Reductase , Autophagy
T3096	Canrenoate potassium	Potassium aldadiene,Canrenoic acid potassium salt,Potassium canrenoate,Soldactone	Glucocorticoid Receptor
	Canrenoate potassium (Soldactone) is a synthetic pregnadiene derivative with anti-aldosterone activity.		Glucocorticoid Receptor
T9245	TRPM4-IN-1	CBA,4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid	TRP/TRPV Channel
	TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM.		TRP/TRPV Channel
T8820	BML-284 hydrochloride	BML-284 HCL,Wnt agonist 1 HCL	Wnt/beta-catenin
	BML-284 hydrochloride (Wnt agonist 1 HCL) is a potent, selective Wnt canonical signaling activator and tubulin polymerization inhibitor.		Wnt/beta-catenin
T6566	Levobupivacaine hydrochloride	Levobupivacaine HCl,(S)-(-)-Bupivacaine HCl,(S)-(-)-Bupivacaine monohydrochloride	Sodium Channel
	Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, which is the pure S(-)-enantiomer of bupivacaine. It was utilized as a long-acting local anesthetic...		Sodium Channel
T1215	Nicardipine hydrochloride	RS-69216,Nicardipine HCl,YC-93 Hydrochloride	Calcium Channel , Adrenergic Receptor , AChR , Autophagy
	Nicardipine hydrochloride (YC-93 Hydrochloride) is the hydrochloride salt form of nicardipine, a synthetic derivative of nitrophenyl-pyridine and potent calcium channel blocker, Nicardipine (Nifedipine Family) blocks cal...		Calcium Channel , Adrenergic Receptor , AChR , Autophagy
T9010	IMM-H007		Others , AMPK
	IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression		Others , AMPK
T1510	Rosuvastatin calcium	ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium	Potassium Channel , HMG-CoA Reductase , Autophagy
	Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemic activity.		Potassium Channel , HMG-CoA Reductase , Autophagy
T9026	MEISi-2	Benzoic acid, 4-hydroxy-, 2-[(Z)-(2-oxo-1(2H)-naphthalenylidene)methyl]hydrazide	Others
	MEISi-2 is a potent MEIS inhibitor (MEISi). MEISi-2 significantly inhibits MEIS-luciferase reporters in vitro.		Others
T7134	Mavacamten	MYK-461,SAR439152	Myosin
	Mavacamten (MYK-461) is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively)		Myosin
T25372	EMD57033	EMD-57033,(+)-EMD 57033,EMD 57033	Calcium Channel , Carbonic Anhydrase
	EMD57033 is a cardiac troponin C (cTnC) activator, a dominant Ca2+ sensitizer, which functions by binding to cardiac/slow skeletal troponin C heterodimers to promote cardiac contraction.		Calcium Channel , Carbonic Anhydrase
T10364	Arbutamine	GP 21213	Adrenergic Receptor
	Arbutamine (GP 21213) is a novel potent non-selective beta-adrenoceptor agonist with alpha-1-sympathomimetic activity.Arbutamine promotes cardiac stress and increases heart rate, cardiac contractility.Arbutamine can be u...		Adrenergic Receptor
T29050	UK 66914	UK66914,UK-66914	Potassium Channel
	UK 66914 is a K(+) channel blocker for the study of cardiac arrhythmias.		Potassium Channel
T24021	E 0747	E-0747,E0747
	E 0747 is an antiarrhythmic agent of class 1C type. E-0747 suppresses arrhythmia by inhibiting the Na channels of cardiac cells.
T11097	Drobuline hydrochloride		Others
	Drobuline hydrochloride is an anti-arrhythmic agent with cardiac depressant activity.		Others
T28686	SB-237376 HCl	SB-237376 hydrochloride	Calcium Channel , Sodium Channel
	SB-237376 HCl (SB-237376 hydrochloride) is a calcium and potassium channel antagonist used in the treatment of cardiac arrhythmias.		Calcium Channel , Sodium Channel
T12078	ML334	LH601A	Nrf2
			Nrf2
TP2058L	Catestatin acetate	Catestatin acetate(142211-96-9 free base)	Endogenous Metabolite , AChR
	Catestatin acetate is a non-competitive antagonist of nAChR and inhibits catecholamine release. Catestatin acetate regulates cardiac function and blood pressure.		Endogenous Metabolite , AChR
T28686L	SB-237376		Calcium Channel , Sodium Channel
	SB-237376 is a calcium and potassium channel antagonist used to treat cardiac arrhythmias.		Calcium Channel , Sodium Channel
T28895	T-0509	T 0509,T0509	Adrenergic Receptor
	T-0509 is a selective beta 1 receptor agonist that increases inotropy in canine ventricular muscle and selectively down-regulates rat cardiac beta 1-adrenoceptors.		Adrenergic Receptor
T31640	Enrasentan	SB-217242,SB 217242,SB217242	Endothelin Receptor
	Enrasentan (sb-217242) is a mixed antagonist of ET(A) and ET(B) receptors that reduces blood pressure, prevents cardiac hypertrophy, and protects myocardial function.		Endothelin Receptor
T12267	NSP-805		PDE
	NSP-805 is a potent and selective guinea pig cardiac phosphodiesterase 3 (PDE3) inhibitor.		PDE
T11239	Ethacizine hydrochloride	NIK-244,Ethacizin,NIK-244 hydrochloride	Sodium Channel
	Ethacizine hydrochloride (NIK-244) has antiarrhythmic activity, and its effects are related to cardiac activity and can be used to study arrhythmias and myocardial infarction.		Sodium Channel
T27630	Isbogrel	CV4151,CV-4151,CV 4151	Prostaglandin Receptor
	Isbogrel (CV4151) is a small molecule thromboxane A2 synthase (TXA2 synthase) inhibitor that can be used to study cardiac arrhythmias, transient ischemic attacks and thrombosis.		Prostaglandin Receptor
T7298	FT011		Others
	FT011, a direct anti-fibrotic agent,attenuates cardiac remodelling and dysfunction in experimental diabetic cardiomyopathy.		Others

Compounds

Zonisamide

T0267

Synonym: AD 810,CI 912

Target: Calcium Channel, Sodium Channel, Carbonic Anhydrase

Dapansutrile

T15052

Synonym:

Target: NOD-like Receptor (NLR), NOD

Target: Wnt/beta-catenin

Target: Sodium Channel

L002

T11807

Synonym:

Target: Others, Histone Acetyltransferase, STAT

Cesium chloride

T8391

Synonym: CsCl

Target: Potassium Channel

GSK329

T24109

Synonym: GSK 329,GSK-329

Target: TRP/TRPV Channel

BML-284

T3144

Synonym: Wnt agonist 1

Target: Wnt/beta-catenin

Mitochondrial fusion promoter M1

T9232

Synonym:

Target: Mitochondrial Metabolism

Clopamide

T6086

Synonym: Brinaldix,Adurix,Aquex

Target: Sodium Channel

Hydrochlorothiazide

T1449

Synonym: HCTZ

Target: Potassium Channel, Carbonic Anhydrase, TGF-beta/Smad

Danicamtiv

T15050

Synonym: MYK-491,SAR 440181

Target: Myosin

Nicardipine

T21454

Synonym: Cardene,Dagan,Antagonil,Flusemide

Target: Calcium Channel

Pinacidil

T12478L

Synonym: S 1230,P 1134,S-1230,P-1134,P1134

Target: Potassium Channel

Brilaroxazine

T14782

Synonym: RP5063

Target: Dopamine Receptor, 5-HT Receptor

(R)-Propranolol hydrochloride

T20898

Synonym: Dexpropranolol hydrochloride,(R)-(+)-Propranolol

Target: Adrenergic Receptor

GS-6201

T15418

Synonym: CVT-6883

Target: Adenosine Receptor

Eleclazine hydrochloride

T15207

Synonym: GS 6615 hydrochloride

Target: Sodium Channel

2,3-Butanedione 2-Monoxime

T2176

Synonym: Diacetyl monoxime,2,3-Butanedione-2-monoxime

Target: Akt

Isoprenaline hydrochloride

T1056

Synonym: NCI-c55630,Isoproterenol hydrochloride,Isoprenaline HCl

Target: PI3K, Endogenous Metabolite, Adrenergic Receptor, PDE

Rosuvastatin

T1676

Synonym: ZD 4522

Target: Potassium Channel, HMG-CoA Reductase, Autophagy

Canrenoate potassium

T3096

Synonym: Potassium aldadiene,Canrenoic acid potassium salt,Potassium canrenoate,Soldactone

Target: Glucocorticoid Receptor

TRPM4-IN-1

T9245

Synonym: CBA,4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid

Target: TRP/TRPV Channel

BML-284 hydrochloride

T8820

Synonym: BML-284 HCL,Wnt agonist 1 HCL

Target: Wnt/beta-catenin

Levobupivacaine hydrochloride

T6566

Synonym: Levobupivacaine HCl,(S)-(-)-Bupivacaine HCl,(S)-(-)-Bupivacaine monohydrochloride

Target: Sodium Channel

Nicardipine hydrochloride

T1215

Synonym: RS-69216,Nicardipine HCl,YC-93 Hydrochloride

Target: Calcium Channel, Adrenergic Receptor, AChR, Autophagy

Synonym: ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium

Target: Potassium Channel, HMG-CoA Reductase, Autophagy

MEISi-2

T9026

Synonym: Benzoic acid, 4-hydroxy-, 2-[(Z)-(2-oxo-1(2H)-naphthalenylidene)methyl]hydrazide

Target: Others

Mavacamten

T7134

Synonym: MYK-461,SAR439152

Target: Myosin

EMD57033

T25372

Synonym: EMD-57033,(+)-EMD 57033,EMD 57033

Target: Calcium Channel, Carbonic Anhydrase

Arbutamine

T10364

Synonym: GP 21213

Target: Adrenergic Receptor

UK 66914

T29050

Synonym: UK66914,UK-66914

Target: Potassium Channel

E 0747

T24021

Synonym: E-0747,E0747

Target:

Drobuline hydrochloride

Synonym: SB-237376 hydrochloride

Target: Calcium Channel, Sodium Channel

Synonym: Catestatin acetate(142211-96-9 free base)

Target: Endogenous Metabolite, AChR

SB-237376

T28686L

Synonym:

Target: Calcium Channel, Sodium Channel

T-0509

T28895

Synonym: T 0509,T0509

Target: Adrenergic Receptor

Enrasentan

T31640

Synonym: SB-217242,SB 217242,SB217242

Target: Endothelin Receptor

Ethacizine hydrochloride

T11239

Synonym: NIK-244,Ethacizin,NIK-244 hydrochloride

Target: Sodium Channel

Isbogrel

T27630

Synonym: CV4151,CV-4151,CV 4151

Target: Prostaglandin Receptor

カタログ番号	製品名	別名	ターゲット
TN1754	Hypaconine		Others
	Hypaconine is a C19-diterpenoid alkaloid isolated from Aconitum and Delphinium spp. It exhibits strong cardiac activity.		Others
TN2054	Periplocymarin		Calcium Channel
	Periplocymarin is a cardiac glycoside with anticancer potential isolated from Periploca sepium and Periploca graeca.		Calcium Channel
TN1039	Tamarixetin	4'-O-Methyl Quercetin	Endogenous Metabolite , Immunology/Inflammation related
	Tamarixetin (4'-O-Methyl Quercetin) (4'-O-Methyl Quercetin) is a natural flavonoid derivative of quercetin, with anti-inflammatory and anti-oxidative effects. Tamarixetin protects against cardiac hypertrophy.		Endogenous Metabolite , Immunology/Inflammation related
T3S0081	Oxypeucedanin	(+-)-Oxypeucedanin,Oxypeucadanin	Potassium Channel
	1. Oxypeucedanin ((+-)-Oxypeucedanin) has novel anticancer effect, mediated via induction of G2-M cell cycle arrest and apoptosis in human prostate carcinoma DU145 cells. 2. Oxypeucedanin is a kind of open-channel blocke...		Potassium Channel
T3408	Syringin	Lilacin,Syringoside,eleutheroside-b,Methoxyconiferine	NOS , Autophagy
	Syringin (eleutheroside-b) is a compound with antitumor, antiproliferative, immunomodulatory and platelet aggregation inhibiting effects.		NOS , Autophagy
TN5073	Strophanthidin	Strophanthidine	ATPase , Calcium Channel
	Strophanthidin (Strophanthidine) can induce calcium overload in vivo.		ATPase , Calcium Channel
T8183	Deslanoside	Desacetyllanatoside C,Deacetyllanatoside C	ATPase , Drug Metabolite
	Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms. Deslanoside inhibits the Na-K-ATPase membrane p...		ATPase , Drug Metabolite
T5247	Trimethylamine N-oxide dihydrate	TMANO Dihydrate	Others , Endogenous Metabolite
	Trimethylamine N-oxide dihydrate (TMANO Dihydrate), a product of the oxidation of trimethylamine, is considered as a protein stabilizer that may serve to counteract urea, the major osmolyte of sharks, skates and rays.		Others , Endogenous Metabolite
T3212	Digoxigenin		Others
	Digoxigenin, a therapeutic drug belonging to the group of cardiac glycosides, is widely used in the management of congestive heart failure and other cardiac diseases		Others
T19466	N8-Acetylspermidine dihydrochloride		Endogenous Metabolite
	N8-Acetylspermidine dihydrochloride is a polyamine.		Endogenous Metabolite
T1670	Lanatoside C	Cedilanid,Ceglunate,Isolanid	ATPase , Virus Protease , Autophagy
	Lanatoside C (Ceglunate) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). Lanatoside C can be used orally or by the intrav...		ATPase , Virus Protease , Autophagy
TN2430	Glucodigifucoside
	Glucodigifucoside, a cardiac glycoside that can be isolated from digitalis seeds, is specifically cytotoxic to human renal adenocarcinoma cells.
T3S0208	Hederagenin 28-O-beta-D-glucopyranosyl ester	Hederagenin-28-beta-D-glucopyranoside	Others
	Hederagenin-28-beta-D-glucopyranoside, a triterpene saponin isolated from Ilex cornuta, protects cardiac myocytes against H2O2-induced damage.		Others
T5665	Geraniol		Others , Endogenous Metabolite , Antifungal
	geraniol provides a potent protective effect against cardiac dysfunction induced by diabetes. This ameliorative effect could be attributed to its suppression of oxidative stress.		Others , Endogenous Metabolite , Antifungal
TN1594	DL-Syringaresinol	(±)-Syringaresinol	Antioxidant , Antifungal
	DL-Syringaresinol ( (±)-Syringaresinol) is a lignan from ginseng berries with anti-inflammatory, antioxidant, analgesic and weak anti-mycobacterial activities.DL-Syringaresinol can delay oxidative stress-induced skin agi...		Antioxidant , Antifungal
T2750	Ginkgolide C	BN-52022	MMP , Sirtuin , Endogenous Metabolite , AMPK
	Ginkgolide C (BN-52022), a natural product, can enhance the cardiac function of rats in the body.		MMP , Sirtuin , Endogenous Metabolite , AMPK
T5940	Proxyphylline	7-(2-Hydroxypropyl)theophylline	PDE , Adenosine Receptor
	Proxyphylline (7-(2-Hydroxypropyl)theophylline) is a dual of adenosine A1/A2a receptor inhibitor and phosphodiesterase (PDE) inhibitor. Proxyphylline acts as a cardiac stimulant, vasodilator and bronchodilator.		PDE , Adenosine Receptor
TCO2745	Cyclic AMP	Adenosine 3',5'-cyclophosphate,cAMP,Cyclic 3',5'-monophosphate adenosine,3',5'-AMP,Adenosine Cyclophosphate	Others , Endogenous Metabolite
	Cyclic AMP (cAMP) (Adenosine 3',5'-cyclophosphate) combined with vitamin C treatment of children with viral myocarditis has exact curative effect, and it can improve cardiac function of patients and improve immune functi...		Others , Endogenous Metabolite
T8195	Lotusine		Others
	Lotusine is a pure alkaloid extracted from the Nelumbo nucifera Gaertn. It shows effects on the action potentials in the myocardium and slow inward current in cardiac Purkinje fibers.		Others
T5968	DL-Homocysteine thiolactone hydrochloride	DL-Homocysteinethiolactone hydrochloride	Endogenous Metabolite
	DL-Homocysteine thiolactone hydrochloride (DL-Homocysteinethiolactone hydrochloride) is a cysteine derivative that binds to and induces conformational changes in various plasma proteins, slowing coagulation and inducing ...		Endogenous Metabolite
TN1923	Mesaconine		IL Receptor , NF-κB
	Mesaconine is an ingredient from Aconitum carmichaelii Debx.. Mesaconine has a cardiac effect and anti-NF-κB activity. Mesaconine may be part of the material basis of Mahuang Fuzi Xixin decoction on anti-inflammation and...		IL Receptor , NF-κB
T5S1708	Dendrobine		Others , Influenza Virus
	1. Dendrobine has a slight but demonstrable analgesic and antipyretic action. 2. Dendrobine produces moderate hyperglycemia, diminishes cardiac activity in large doses, lowers the blood pressure. 3. Dendrobine on the ele...		Others , Influenza Virus
T4550	Ajmaline	Cardiorythmine,Raugalline,Tachmalin,(+)-Ajmaline	Sodium Channel
	Ajmaline (Cardiorythmine) is a class Ia anti-arrhythmic compound that is widely used for the diagnosis of Brugada syndrome and the acute treatment of atrial or ventricular tachycardia. Ajmaline inhibits cardiac Kv1.5 and...		Sodium Channel
T3921	Punicalagin		SARS-CoV , HBV
	Punicalagin is a major ellagitannin found in pomegranates that is reported to produce antioxidant, anti-inflammatory, and anticancer effects. It has been shown to prevent high-fat diet-induced obesity-associated accumula...		SARS-CoV , HBV
T1083	Theophylline	Theo-24,1,3-Dimethylxanthine	Endogenous Metabolite , HDAC , PDE , Adenosine Receptor , Autophagy
	Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3...
T3S0629	Delsoline	Belsoline	Others
	1. Delsoline (Belsoline) has hypotensive effects.2. Delsoline is not only effective in preventing ventricular fibrillation and arrythmia, but can raise the intebsity of the threthold of electrical shocks to cause ventric...		Others
T0266	Quinidine hydrochloride monohydrate	Quinidine hydrochloride	Potassium Channel , Sodium Channel , Parasite
	Quinidine hydrochloride monohydrate is an optical isomer of quinine, extracted from the bark of the Cinchona tree and similar plant species. It prolongs cellular action potential and decreases automaticity. This alkaloid...		Potassium Channel , Sodium Channel , Parasite
T5S0890	Oleandrin	Neriostene,Folinerin,Foliandrin	Apoptosis , ATPase , Potassium Channel , Sodium Channel
	1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional levels. 2. Oleandrin are known to inhibit the Na, ...		Apoptosis , ATPase , Potassium Channel , Sodium Channel
T41245	Trimethylamine N-oxide		Reactive Oxygen Species , NOD-like Receptor (NLR) , TGF-beta/Smad
	Trimethylamine N-oxide (TMAO) is a colorless amine oxide produced from choline, betaine, and carnitine via intestinal microbial metabolism that accumulates in tissues of marine animals and prevents the protein-damaging e...
T2S1008	Oxysophoridine	Sophoridine N-oxide	Apoptosis , Antioxidant
	Oxysophoridine (Sophoridine N-oxide) has a protective effect on focal cerebral ischemic injury through antioxidant and anti-apoptotic mechanisms; it may be a potential neuroprotective agent for cerebral ischemia injury, ...		Apoptosis , Antioxidant
T4A2399	Cinobufotalin		IL Receptor , Akt , MRP , P-gp
	Cinobufotalin is a main cardiac toxin in toad, it is a novel anti-HCC agent, it induces growth inhibition and apoptosis in cultured HCC cells through ceramide production. Cinobufotalin is also an effective reversal agent...		IL Receptor , Akt , MRP , P-gp
T3893	Forsythoside B		TNF , NF-κB
	Forsythoside B binds to LPS and reduces the biological activity of serum LPS, and inhibits NF-κB activation. Forsythoside B inhibits the inflammatory response and has antioxidant properties. Potent neuroprotective effect...		TNF , NF-κB
T3753	Sinapinic Acid	Sinapic acid,Synapoic acid	Apoptosis , RAAS , Reactive Oxygen Species , HDAC
	Sinapinic Acid (Synapoic acid) protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cytokine expression. Sinap...		Apoptosis , RAAS , Reactive Oxygen Species , HDAC
T2S2215	Crebanine		Apoptosis , Others , Akt
	1. Crebanine iv 5mg/kg can eonvert BaCl_2-induced arrhythmia into sinus rhythm in rats, and can significantly increase the tolerant dose of aconitine to produce ventrieular fibrillation(VF) and cardiac arrest (CA) in rat...		Apoptosis , Others , Akt
TN5289	Thevebioside	Digitoxigenin glucosylthevetoside
	Thevebioside and digitoxin are cardiac glycosides, have cardiac action.
T16332	NKH477	Colforsin dapropate hydrochloride	NMDAR
	NKH477 is a novel water-soluble forskolin derivative that improves cardiac failure mainly through its beneficial effects on diastolic cardiac function. NKH477 shows an antiproliferative effect in vivo with an altered cyt...		NMDAR
TN4949	Sarmentocymarin		Others
	Sarmentocymarin is a cardiac glucoside.		Others
T10554	Bixin		Others
	Bixin is isolated from the seeds of Bixa orellana and possesses anti-tumor, anti-inflammatory, and antioxidant activities. Bixin treatment ameliorated cardiac dysfunction through inhibiting fibrosis, inflammation, and RO...		Others
TN1367	Alismol		Potassium Channel , Calcium Channel , PI3K
	Alismol has antihypertensive action, it decreases cardiac output, heart rate and left ventricular pressure, but it increases coronary flow, it has been used for the prevention of anginal attacks.		Potassium Channel , Calcium Channel , PI3K
T11513	Gum arabic	Arabic gum	Others
	Gum Arabic, a branched-chain, complex polysaccharide derived from A. Senegal, exhibits antioxidant properties and offers protection against experimental hepatic, renal, and cardiac toxicities. Additionally, it finds appl...		Others
TN1912	Marinobufogenin	Marinobufagenin	ATPase , EGFR
	Marinobufagenin, a cardiotonic steroid, its increased concentrations are important in the cardiac disease and oxidant stress state seen with renal failure.		ATPase , EGFR
TN1797	Isorhoifolin		Adrenergic Receptor
	Isorhoifolin and vicenin II are main compounds of ethyl acetate fraction (EAcF) obtained from Erythrina velutina leaves, EAcF increases the cardiac contractile force by increasing the l-type calcium current and activatin...		Adrenergic Receptor
TN5141	Thevetin B		ATPase , Potassium Channel , Sodium Channel
	Thevetin B is a cardiac glycoside and an inhibitor of Na+-, K+-dependent adenosinetriphosphatase (Na+,K+-ATPase) from Thevetia peruviana.		ATPase , Potassium Channel , Sodium Channel
T80702	α-Thevetin B
	α-Thevetin B (Compound 24), a cardiac glycoside extracted from Thevetia peruviana, has applications in research concerning lung, gastric, and pancreatic cancers [1].
T83454	13-Hydroxylupanine hydrochloride	Hydroxylupanine hydrochloride
	13-Hydroxylupanine, a characteristic alkaloid of sweet lupins, inhibits ganglionic transmission, reduces cardiac contractility, and induces contraction of uterine smooth muscle [1].
T79982	2'-epi-2'-O-Acetylthevetin B	GHSC-74	Apoptosis
	2'-Epi-2'-O-Acetylthevetin B (GHSC-74), a cardiac glycoside extractable from Cerbera manghas L. seeds, diminishes cell viability, triggers apoptosis, and disrupts mitochondrial membrane potential in HepG2 cells [1].		Apoptosis
T78489	Lotusine hydroxide
	Lotusine (hydroxide), a pure alkaloid isolated from the green seed embryos of Nelumbo nucifera Gaertn, influences action potentials in myocardial tissue and the slow inward current in cardiac Purkinje fibers [1].
T82782	Cannogenol 3-O-β-gentiobiosyl-(1→4)-α-L-thevetoside
	Cannogenol 3-O-β-gentiobiosyl-(1→4)-α-L-thevetoside (Compound 12), a cardiac glycoside extracted from Thevetia peruviana seeds, exhibits cytotoxic effects on SW1990 and MGC-803 cells with IC50 values of 9.52 and 7.70 μM,...
T83915	Norbixin hydrate
	Norbixin, a carotenoid found in B. orellana, exhibits various biological activities including binding to the peroxisome proliferator-activated receptor γ (PPARγ) with a Ki of 1.15 µM in a cell-free assay. At a dosage of ...

天然物製品

Target: Calcium Channel

Tamarixetin

TN1039

Synonym: 4'-O-Methyl Quercetin

Target: Endogenous Metabolite, Immunology/Inflammation related

Oxypeucedanin

T3S0081

Synonym: (+-)-Oxypeucedanin,Oxypeucadanin

Target: Potassium Channel

Syringin

T3408

Synonym: Lilacin,Syringoside,eleutheroside-b,Methoxyconiferine

Target: NOS, Autophagy

Strophanthidin

TN5073

Synonym: Strophanthidine

Target: ATPase, Calcium Channel

Deslanoside

T8183

Synonym: Desacetyllanatoside C,Deacetyllanatoside C

Target: ATPase, Drug Metabolite

Trimethylamine N-oxide dihydrate

T5247

Synonym: TMANO Dihydrate

Target: Others, Endogenous Metabolite

N8-Acetylspermidine dihydrochloride

T19466

Synonym:

Target: Endogenous Metabolite

Lanatoside C

T1670

Synonym: Cedilanid,Ceglunate,Isolanid

Target: ATPase, Virus Protease, Autophagy

Hederagenin 28-O-beta-D-glucopyranosyl ester

T3S0208

Synonym: Hederagenin-28-beta-D-glucopyranoside

Target: Others, Endogenous Metabolite, Antifungal

DL-Syringaresinol

TN1594

Synonym: (±)-Syringaresinol

Target: Antioxidant, Antifungal

Ginkgolide C

T2750

Synonym: BN-52022

Target: MMP, Sirtuin, Endogenous Metabolite, AMPK

Proxyphylline

T5940

Synonym: 7-(2-Hydroxypropyl)theophylline

Target: PDE, Adenosine Receptor

Cyclic AMP

TCO2745

Synonym: Adenosine 3',5'-cyclophosphate,cAMP,Cyclic 3',5'-monophosphate adenosine,3',5'-AMP,Adenosine Cyclophosphate

Target: Others, Endogenous Metabolite

DL-Homocysteine thiolactone hydrochloride

T5968

Synonym: DL-Homocysteinethiolactone hydrochloride

Target: Endogenous Metabolite

Mesaconine

TN1923

Synonym:

Target: IL Receptor, NF-κB

Dendrobine

T5S1708

Synonym:

Target: Others, Influenza Virus

Ajmaline

T4550

Synonym: Cardiorythmine,Raugalline,Tachmalin,(+)-Ajmaline

Target: Sodium Channel

Punicalagin

T3921

Synonym:

Target: SARS-CoV, HBV

Theophylline

T1083

Synonym: Theo-24,1,3-Dimethylxanthine

Target: Endogenous Metabolite, HDAC, PDE, Adenosine Receptor, Autophagy

Quinidine hydrochloride monohydrate

T0266

Synonym: Quinidine hydrochloride

Target: Potassium Channel, Sodium Channel, Parasite

Oleandrin

T5S0890

Synonym: Neriostene,Folinerin,Foliandrin

Target: Apoptosis, ATPase, Potassium Channel, Sodium Channel

Trimethylamine N-oxide

T41245

Synonym:

Target: Reactive Oxygen Species, NOD-like Receptor (NLR), TGF-beta/Smad

Oxysophoridine

T2S1008

Synonym: Sophoridine N-oxide

Target: Apoptosis, Antioxidant

Cinobufotalin

T4A2399

Synonym:

Target: IL Receptor, Akt, MRP, P-gp

Synonym: Sinapic acid,Synapoic acid

Target: Apoptosis, RAAS, Reactive Oxygen Species, HDAC

Crebanine

T2S2215

Synonym:

Target: Apoptosis, Others, Akt

Thevebioside

TN5289

Synonym: Digitoxigenin glucosylthevetoside

Target:

NKH477

T16332

Synonym: Colforsin dapropate hydrochloride

Target: Potassium Channel, Calcium Channel, PI3K

Synonym: Marinobufagenin

Target: Adrenergic Receptor

Thevetin B

TN5141

Synonym:

Target: ATPase, Potassium Channel, Sodium Channel

13-Hydroxylupanine hydrochloride

T83454

Synonym: Hydroxylupanine hydrochloride

Target:

2'-epi-2'-O-Acetylthevetin B

Cannogenol 3-O-β-gentiobiosyl-(1→4)-α-L-thevetoside

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-01049	Cardiac phospholamban/PLN Protein, Human, Recombinant (GST)	Human	P. pastoris (Yeast)
	Cardiac phospholamban/PLN Protein, Human, Recombinant (GST) is expressed in yeast with N-GST tag. The predicted molecular weight is 33.1 kDa and the accession number is P26678.
TMPH-01176	CSRP3 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	CSRP3 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-00780	CACNA1C Protein, Guinea Pig, Recombinant (His)	Guinea pig	E. coli
	Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Mediates influx of calcium ions into the cytoplasm, and thereby triggers calcium release from the sarcoplasm...
TMPY-04552	AKT1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	v-akt murine thymoma viral oncogene homolog 1 (AKT1), or protein kinase B-alpha (PKB-ALPHA) is a serine-threonine protein kinase, belonging to the Protein Kinase Superfamily. AKT1 is a major mediator of the responses to ...
TMPJ-00261	TGF beta 2 Protein, Mouse/Rat, Recombinant	Mouse,Rat	HEK293 Cells
	Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofaci...
TMPY-00117	FGF-16 Protein, Human, Cynomolgus, Recombinant	Human,Cynomolgus	Baculovirus Insect Cells
	Fibroblast growth factor 16 (FGF16) is preferentially expressed in the heart after birth, suggesting its regulation is associated with tissue-specific chromatin remodeling and DNA-protein interactions. Mutation of the ME...
TMPY-05004	FGF-4 Protein, Human, Recombinant	Human	E. coli
	FGF (fibroblast growth factor) signalling is known to be required for many aspects of mesoderm formation and patterning during Xenopus development and has been implicated in regulating genes required for the specificati...
TMPY-00566	CCL18 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its...
TMPJ-00044	TNNC1 Protein, Human, Recombinant (His)	Human	E. coli
	Troponin I, also known as TNI, is a 24 kDa component of a protein complex on striated muscle thin filaments.Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I...
TMPK-01369	S100B Protein, Canine, Recombinant (hFc)	Canine	HEK293 Cells
	S100B, a calcium-binding protein of the EF-hand type exerts both intracellular and extracellular functions.The intracellular, and extracellular, roles of S100B are attractive therapeutic targets for the treatment of both...
TMPH-01231	DIP2A Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Catalyzes the de novo synthesis of acetyl-CoA in vitro. Promotes acetylation of CTTN, possibly by providing the acetyl donor, ensuring correct dendritic spine morphology and synaptic transmission. Binds to follistatin-re...
TMPH-01230	DIP2A Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Catalyzes the de novo synthesis of acetyl-CoA in vitro. Promotes acetylation of CTTN, possibly by providing the acetyl donor, ensuring correct dendritic spine morphology and synaptic transmission. Binds to follistatin-re...
TMPH-00286	Myotrophin Protein, Bovine, Recombinant (His)	Bovine	P. pastoris (Yeast)
	Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Plays a ro...
TMPJ-00785	FABP3 Protein, Human, Recombinant (His)	Human	E. coli
	Fatty Acid Binding Protein 3 (FABP3) is a small cytoplasmic protein (15 kDa) that is released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, FABP3 is in...
TMPJ-00875	NPPB Protein, Human, Recombinant (His)	Human	E. coli
	Human Natriuretic peptides B acts as a cardiac hormone; it is associated with many biological actions, such as diuresis, natriuresis, vasorelaxation, which inhibits the secretion of rennin and aldosterone. It acts as a p...
TMPK-01286	MMP-8 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Alteration of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) expression has been studied for various cardiac diseases, including dilated cardiomyopathy (DCM), with the significance o...
TMPH-02103	SRF Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Together with ...
TMPJ-00882	Desmin Protein, Human, Recombinant (His)	Human	E. coli
	Desmin is a cytoplasmic protein and belongs to the intermediate filament family. interacts with DST and MTM1. Desmin is only expressed in vertebrates, however homologous proteins are found in many organisms. Desmin is th...
TMPK-01048	Aggrecan Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Aggrecan is a large proteoglycan that forms giant hydrated aggregates with hyaluronan in the extracellular matrix (ECM). The extraordinary resistance of these aggregates to compression explains their abundance in articul...
TMPJ-00086	CT-1 Protein, Human, Recombinant (His)	Human	E. coli
	Cardiotrophin-1, also known as CT-1 and CTF1, is a member of the IL-6 superfamily. It is a sreted cytokine that is expressed in heart, skeletal muscle, prostate and ovary, and to lower levels in lung, kidney, pancreas, t...
TMPJ-00190	CD38 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicoti...
TMPJ-00931	Serpin A4 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serpin Peptidase Inhibitor, Clade A (α-1 Antiproteinase, Antitrypsin), Member 4 (Serpin A4) is a member of the Serpin family. Serpin A4 exists as a monomer and some homodimers. Serpin A4 is expressed by the liver and sec...
TMPH-02634	TRIM63 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein...
TMPJ-01364	LMCD1 Protein, Human, Recombinant (His)	Human	E. coli
	LMCD1 is transcriptional cofactor which contains a cysteine-rich domain in the N-terminal region and 2 LIM domains in the C-terminal region. It also has several potential phosphorylation and N-myristoylation sites and a ...
TMPH-01271	TRIM63 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein...
TMPY-03600	TPM4 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	TPM4, also known as tropomyosin 4, is a member of the tropomyosin family. Members of this family are actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-mu...
TMPH-03282	TRIM63 Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein...
TMPJ-00753	Myoglobin Protein, Human, Recombinant (His)	Human	E. coli
	Myoglobin(MB) is a cytoplasmic protein expressed in myocytes of the heart and skeletal muscle that reversibly binds oxygen. It belongs to the globin family. Functions of myoglobin include oxygen storage and transport, as...
TMPJ-01209	BTNL9 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Butyrophilin-Like Protein 9 (BTNL9) is single-pass type I membrane protein member of the BTN/MOG family that belongs to the immunoglobulin superfamily. BTNL9 consists of two domains: one B30.2/SPRY domain and one Ig-like...
TMPJ-01194	BTNL9 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Butyrophilin-Like Protein 9 (BTNL9) is single-pass type I membrane protein member of the BTN/MOG family that belongs to the immunoglobulin superfamily. BTNL9 consists of two domains: one B30.2/SPRY domain and one Ig-like...
TMPJ-01195	BTNL9 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Butyrophilin-Like Protein 9 (BTNL9) is single-pass type I membrane protein member of the BTN/MOG family that belongs to the immunoglobulin superfamily. BTNL9 consists of two domains: one B30.2/SPRY domain and one Ig-like...
TMPJ-01112	PRKG1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	cGMP-Dependent Protein Kinase 1 (PRKG1) belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family. PRKG1 contains one AGC-kinase C-terminal domain, two cyclic nucleotide-binding domains, and one pro...
TMPY-03456	SRFBP1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	SRFBP1 contains 7 WD repeats and belongs to the WD repeat STRAP family. SRFBP1 may play a role in the cellular distribution of the SMN complex. The SMN complex plays an essential role in spliceosomal snRNP assembly in th...
TMPJ-00553	Lp-PLA2/PLA2G7 Protein, Human, Recombinant (aa 22-441, His)	Human	HEK293 Cells
	Platelet-Activating Factor Acetylhydrolase (PAFAH) is a secreted enzyme which belongs to the AB hydrolase superfamily and Lipase family and catalyzes the degradation of platelet-activating factor to biologically inactive...
TMPJ-00402	CD117 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	C-Kit/SCF R is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to ...
TMPJ-01126	RheB Protein, Human, Recombinant (GST)	Human	E. coli
	GTP-Binding Protein Rheb (RHEB) is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. Highest levels of RHEB can be foun...
TMPJ-00790	GSN Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	Gelsolin is a calcium-activated actin filament severing and capping protein found in many cell types and as a secreted form in the plasma of vertebrates. Gelsolin is composed of six of these domains, termed G1-6. Some re...
TMPU-00002	SOS1-Cat Protein, Human, Recombinant (His)	Human	E. coli
	Defects in SOS1 are the cause of gingival fibromatosis 1 (GGF1) [MIM:135300]; also known as GINGF1. Gingival fibromatosis is a rare overgrowth condition. Defects in SOS1 are the cause of Noonan syndrome type 4 (NS4) [MIM...
TMPJ-00091	G-CSF Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Granulocyte colony-stimulating factor (G-CSF) is a growth factor and an essential cytokine which belongs to the IL-6 superfamily. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis ...
TMPH-02222	TEAD1 Protein, Human, Recombinant (His)	Human	E. coli
	Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is...
TMPH-01280	EGLN1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of th...
TMPY-02708	NRG4 Protein, Human, Recombinant	Human	E. coli
	NRG4 (neuregulin 4) is a member of the neuregulin protein family. The neuregulins consist of four structurally-related proteins that are part of the EGF family of proteins. It has been shown that these proteins have dive...
TMPJ-01286	ProHB-EGF Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Heparin-binding EGF-like growth factor (HB-EGF) is a 1216 kDa member of the epidermal growth factor (EGF) family. It possesses an EGFlike domain, and a heparin-binding motif. Mature HBEGF is a soluble peptide that ari...
TMPJ-01158	ALK-2/ACVR1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Activin RIA, also known as ALK-2, TSK-7L, SKR1, TSR-I, and ACTR-I, is a glycosylated 65 kDa type I receptor in the TGF-beta serine/threonine kinase receptor family. Binding of TGF-beta superfamily ligands induces formati...
TMPY-02648	PACAP receptor/ADCYAP1R1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Pituitary adenylate cyclase activating polypeptide (PACAP, Adcyap1) activation of PAC1 receptors ( Adcyap1r1) significantly increases excitability of guinea pig cardiac neurons. This modulation of excitability is mediate...
TMPY-02977	PDE1C Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	PDE1C belongs to the cyclic nucleotide phosphodiesterase family, PDE1 subfamily. Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3' cyclic phosphate bonds ...
TMPJ-00527	SP-D Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Surfactant Pulmonary-Associated Protein D (SP-D) is a 43 kDa member of the collectin family of innate immune modulators. Its principal components consist of a collagen-like region and a C-terminal carbohydrate recognitio...
TMPY-03438	Calsequestrin 1 Protein, Human, Recombinant	Human	E. coli
	Calsequestrin-1 is an isoform of calsequestrin. Calsequestrin is a calcium-binding protein of the sarcoplasmic reticulum. It helps hold calcium in the cisterna of the sarcoplasmic reticulum after a muscle contraction,...
TMPY-02081	PDE2A Protein, Human, Recombinant (aa 215-900, His)	Human	Baculovirus Insect Cells
	cGMP-dependent 3',5'-cyclic phosphodiesterase, also known as cyclic GMP-stimulated phosphodiesterase and PDE2A, is a peripheral membrane protein that belongs to the cyclic nucleotide phosphodiesterase family and PDE2 sub...
TMPY-02242	Serpin B6 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	SerpinB6, also known as Cytoplasmic antiproteinase, Peptidase inhibitor 6, Placental thrombin inhibitor, SERPINB6 and PI-6, is a cytoplasm protein that belongs to the serpin family and Ov-serpin subfamily. SerpinB6 / PI-...
------------------------ More ------------------------

Cardiac phospholamban/PLN Protein, Human, Recombinant (GST)

TMPH-01049

Species: Human

Expression System: P. pastoris (Yeast)

CSRP3 Protein, Human, Recombinant (His & SUMO)

TMPH-01176

Species: Human

Expression System: E. coli

CACNA1C Protein, Guinea Pig, Recombinant (His)

TMPH-00780

Species: Guinea pig

Expression System: E. coli

AKT1 Protein, Human, Recombinant (His)

TMPY-04552

Species: Human

Expression System: Baculovirus Insect Cells

TGF beta 2 Protein, Mouse/Rat, Recombinant

TMPJ-00261

Species: Mouse,Rat

Expression System: HEK293 Cells

FGF-16 Protein, Human, Cynomolgus, Recombinant

TMPY-00117

Species: Human,Cynomolgus

Expression System: Baculovirus Insect Cells

FGF-4 Protein, Human, Recombinant

TMPY-05004

Species: Human

Expression System: E. coli

CCL18 Protein, Human, Recombinant (His)

TMPY-00566

Species: Human

Expression System: P. pastoris (Yeast)

TNNC1 Protein, Human, Recombinant (His)

TMPJ-00044

Species: Human

Expression System: E. coli

S100B Protein, Canine, Recombinant (hFc)

TMPK-01369

Species: Canine

Expression System: HEK293 Cells

DIP2A Protein, Human, Recombinant (His)

TMPH-01231

Species: Human

Expression System: Baculovirus Insect Cells

DIP2A Protein, Human, Recombinant (hFc)

TMPH-01230

Species: Human

Expression System: HEK293 Cells

Myotrophin Protein, Bovine, Recombinant (His)

TMPH-00286

Species: Bovine

Expression System: P. pastoris (Yeast)

FABP3 Protein, Human, Recombinant (His)

TMPJ-00785

Species: Human

Expression System: E. coli

NPPB Protein, Human, Recombinant (His)

TMPJ-00875

Species: Human

Expression System: E. coli

MMP-8 Protein, Cynomolgus, Recombinant (His)

TMPK-01286

Species: Cynomolgus

Expression System: HEK293 Cells

SRF Protein, Human, Recombinant (His)

TMPH-02103

Species: Human

Expression System: P. pastoris (Yeast)

Desmin Protein, Human, Recombinant (His)

TMPJ-00882

Species: Human

Expression System: E. coli

Aggrecan Protein, Human, Recombinant (His)

TMPK-01048

Species: Human

Expression System: HEK293 Cells

CT-1 Protein, Human, Recombinant (His)

TMPJ-00086

Species: Human

Expression System: E. coli

CD38 Protein, Mouse, Recombinant (hFc)

TMPJ-00190

Species: Mouse

Expression System: HEK293 Cells

Serpin A4 Protein, Human, Recombinant (His)

TMPJ-00931

Species: Human

Expression System: HEK293 Cells

TRIM63 Protein, Mouse, Recombinant (His & Myc)

TMPH-02634

Species: Mouse

Expression System: E. coli

LMCD1 Protein, Human, Recombinant (His)

TMPJ-01364

Species: Human

Expression System: E. coli

TRIM63 Protein, Human, Recombinant (His & Myc)

TMPH-01271

Species: Human

Expression System: E. coli

TPM4 Protein, Human, Recombinant (His)

TMPY-03600

Species: Human

Expression System: HEK293 Cells

TRIM63 Protein, Rat, Recombinant (His & Myc)

TMPH-03282

Species: Rat

Expression System: E. coli

Myoglobin Protein, Human, Recombinant (His)

TMPJ-00753

Species: Human

Expression System: E. coli

BTNL9 Protein, Mouse, Recombinant (hFc)

TMPJ-01209

Species: Mouse

Expression System: HEK293 Cells

BTNL9 Protein, Human, Recombinant (hFc)

TMPJ-01194

Species: Human

Expression System: HEK293 Cells

BTNL9 Protein, Human, Recombinant (His)

TMPJ-01195

Species: Human

Expression System: HEK293 Cells

PRKG1 Protein, Human, Recombinant (His)

TMPJ-01112

Species: Human

Expression System: HEK293 Cells

SRFBP1 Protein, Human, Recombinant (His & GST)

TMPY-03456

Species: Human

Expression System: Baculovirus Insect Cells

Lp-PLA2/PLA2G7 Protein, Human, Recombinant (aa 22-441, His)

TMPJ-00553

Species: Human

Expression System: HEK293 Cells

CD117 Protein, Human, Recombinant (hFc)

TMPJ-00402

Species: Human

Expression System: HEK293 Cells

RheB Protein, Human, Recombinant (GST)

TMPJ-01126

Species: Human

Expression System: E. coli

GSN Protein, Human, Recombinant (mFc)

TMPJ-00790

Species: Human

Expression System: HEK293 Cells

SOS1-Cat Protein, Human, Recombinant (His)

TMPU-00002

Species: Human

Expression System: E. coli

G-CSF Protein, Mouse, Recombinant (His)

TMPJ-00091

Species: Mouse

Expression System: HEK293 Cells

TEAD1 Protein, Human, Recombinant (His)

TMPH-02222

Species: Human

Expression System: E. coli

EGLN1 Protein, Human, Recombinant (His & Myc)

TMPH-01280

Species: Human

Expression System: E. coli

NRG4 Protein, Human, Recombinant

TMPY-02708

Species: Human

Expression System: E. coli

proHB-EGF Protein, Human, Recombinant (His)

TMPJ-01286

Species: Human

Expression System: HEK293 Cells

ALK-2/ACVR1 Protein, Human, Recombinant (hFc)

TMPJ-01158

Species: Human

Expression System: HEK293 Cells

PACAP receptor/ADCYAP1R1 Protein, Human, Recombinant (hFc)

TMPY-02648

Species: Human

Expression System: HEK293 Cells

PDE1C Protein, Human, Recombinant (His & GST)

TMPY-02977

Species: Human

Expression System: Baculovirus Insect Cells

SP-D Protein, Human, Recombinant (His)

TMPJ-00527

Species: Human

Expression System: HEK293 Cells

Calsequestrin 1 Protein, Human, Recombinant

TMPY-03438

Species: Human

Expression System: E. coli

PDE2A Protein, Human, Recombinant (aa 215-900, His)

TMPY-02081

Species: Human

Expression System: Baculovirus Insect Cells

Serpin B6 Protein, Human, Recombinant (His)

TMPY-02242

Species: Human

Expression System: Baculovirus Insect Cells

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カタログ番号	製品名
L6140	Saccharide and Glycoside Natural Product Library	362 compounds
	A unique collection of 362 saccharides and glycosides compounds can be used for HTS and HCS；
L7300	Potassium Channel Blocker Library	152 compounds
	A unique collection of 152 potassium channel blockers and agonists for high throughput and high content screening;
L7200	Calcium Channel Compound Library	140 compounds
	A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;
L5510	Drug-induced Liver Injury (DILI) Compound Library	1001 compounds
	A unique collection of 1001 hepatotoxicity causing compounds, a powerful tool for drug toxicity study, can be used for HTS and HCS screening；
L7110	Anti-Hypertension Compound Library	678 compounds
	678 hypertension-related small molecules for high-throughput and high-content screening.

ライブラリー

Saccharide and Glycoside Natural Product Library

L6140

Compounds: 362

Potassium Channel Blocker Library

L7300

Compounds: 152

Calcium Channel Compound Library

L7200

Compounds: 140

Drug-induced Liver Injury (DILI) Compound Library

L5510

Compounds: 1001

Anti-Hypertension Compound Library

L7110

Compounds: 678