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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TP1200 | CGRP (83-119), rat TFA | Calcitonin Gene Related Peptide(83-119), rat TFA | Others |
CGRP (83-119), rat TFA (Calcitonin Gene Related Peptide(83-119), rat TFA) is a 37 amino acid calcitonin family of neuropeptide, acts through calcitonin receptor-like receptor. | |||
TP1202 | Calcitonin Gene Related Peptide (CGRP) II, rat | CGRP II, rat | |
Calcitonin Gene Related Peptide II is a potent, long-lasting vasodilator; activation of CGRP receptors on pancreatic β-cells increases plasma levels of pancreatic enzymes. | |||
T76032 | Calcitonin Gene Related Peptide (CGRP) II, rat TFA | ||
Calcitonin Gene-Related Peptide (CGRP) II, rat TFA, functions as a potent and enduring vasodilator by activating CGRP receptors. This compound is utilized in cardiovascular disease research [1]. | |||
T76363 | [Tyr22] Calcitonin Gene Related Peptide, (22-37), rat | ||
[Tyr22] Calcitonin Gene Related Peptide (22-37), rat, refers to a fragment (amino acids 22-37) of the rat calcitonin gene-related peptide (CGRP) that targets the CGRP receptor and adenylate cyclase. While calcitonin is p... | |||
TP2465 | PHYD protein, Arabidopsis | Phyd gene product,Phyd protein | |
PHYD protein, Arabidopsis belongs to the phytochrome apoprotein family in Arabidopsis. | |||
TP1203 | CGRP(83-119), rat | Calcitonin Gene Related Peptide (CGRP) (83-119), rat | |
Calcitonin Gene Related Peptide (CGRP) (83-119), rat is a 37 amino acid calcitonin family of neuropeptide, acts through calcitonin receptor-like receptor. | |||
T9266 | Fatostatin | Lipid , Fatty Acid Synthase | |
Fatostatin is a specific inhibitor of SREBP activation, it impairs the activation of SREBP-1 and SREBP-2. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. | |||
TP1201 | CGRP II, rat (TFA) (99889-63-1 free base) | Calcitonin Gene Related Peptide (CGRP) II, rat (TFA),CGRP II, rat (TFA) | |
Calcitonin Gene Related Peptide (CGRP) II, rat (TFA) is a neuropeptide with 37 amino acid. | |||
T17194 | Ubrogepant | MK-1602 | CGRP Receptor |
Ubrogepant (MK-1602) is an antagonist of calcitonin gene-related peptide receptor that can be used in the acute treatment of migraine studies. | |||
T16040 | Mepazine | Pecazine | Apoptosis , MALT |
Mepazine (Pecazine) is a potent and selective inhibitor of MALT1. Mepazine inhibits GSTMALT1 full length and GSTMALT1 325-760 with IC50s of 0.83 μM and 0.42 μM. Mepazine enhances apoptosis and affects the cell viability. | |||
T12293L | Olcegepant | BIBN-4096,BIBN 4096BS | CGRP Receptor |
Olcegepant (BIBN-4096) is an effective and selective non-peptide calcitonin gene-related peptide 1 (CGRP1) receptor antagonist (IC50 of 0.03 nM and Ki of 14.4 pM for human CGRP). | |||
T36670 | JNJ-67856633 | MALT | |
JNJ-67856633 is an orally active, first-in-class, potent, selective and allosteric inhibitor of MALT1 protease . JNJ-67856633 lead to tumor stasis in some cases. | |||
T9216 | MLT-943 | MLT943 | MALT |
MLT-943 is a potent, selective and orally active MALT1 protease inhibitor. [1]. | |||
TP1040 | Calcitonin (salmon) | Calcitonin salmon,Salmon calcitonin | CGRP Receptor |
Calcitonin (salmon), a calcium regulating hormone, is used to treat osteoporosis in women who are at least 5 years past menopause. | |||
T1724 | SCR7 pyrazine | SCR7 | Apoptosis , DNA/RNA Synthesis , CRISPR/Cas9 |
SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ). | |||
T8682 | Vazegepant hydrochloride | Vazegepant HCl | CGRP Receptor |
Vazegepant hydrochloride (Vazegepant HCl) is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study. | |||
T23383 | SR11237 | SR 11237 | Others , RAR/RXR |
SR11237 is a Pan retinoid X receptor (RXR) agonist. SR11237 causes RXR/RXR homodimers to form and transactivate a reporter gene containing a RXR-response element. | |||
T4610 | Rimegepant | BMS 927711,BMS-927711,BMS927711,BHV-3000 | CGRP Receptor |
Rimegepant (BMS 927711) is a highly potent, oral calcitonin gene-related peptide (CGRP) receptor antagonist with a Ki value of 0.027 nM. | |||
T4641 | Branaplam | LMI 070,NVS-SM1 | Others , Potassium Channel , DNA/RNA Synthesis |
Branaplam (LMI 070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator. | |||
T1676 | Rosuvastatin | ZD 4522 | Potassium Channel , HMG-CoA Reductase , Autophagy |
Rosuvastatin (ZD 4522) is an antilipemic agent that competitively inhibits hydroxymethyl-glutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting... | |||
T6832 | Fatostatin hydrobromide | Fatostatin HBr,Fatostatin A,Fatostatin A HBr,Fatostatin | NPC1L1 , Fatty Acid Synthase |
Fatostatin hydrobromide (Fatostatin A HBr) ia an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2. | |||
T1692 | 3-(3,4-Dimethoxyphenyl)propanoic acid | 3,4-Dimethoxyhydrocinnamic acid | Aromatase |
3-(3,4-Dimethoxyphenyl)propanoic acid (3,4-Dimethoxyhydrocinnamic acid) is an orally active short-chain fatty acid (SCFAs). It promotes γ-globin gene expression and erythropoiesis in vivo and can be used in beta hemoglob... | |||
T2350 | MALT1 inhibitor MI-2 | MALT1 inhibitor,MI 2,MI 2 (MALT1 inhibitor) | MALT |
MI-2 (MALT1 inhibitor) is an irreversible MALT1 inhibitor. | |||
T5045 | GSK4112 | 1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate,SR6452 | Autophagy |
GSK4112 (SR6452) is a Rev-erbα agonist with EC50 of 0.4 μM, also is a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα. | |||
T1826 | PI3K-IN-1 | Voxtalisib Analogue,Voxtalisib (SAR245409, XL765) Analogue,XL765,SAR245409 | DNA-PK , PI3K |
PI3K-IN-1 (Voxtalisib Analogue) is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits DNA-PK and mTOR. | |||
T1510 | Rosuvastatin calcium | ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium | Potassium Channel , HMG-CoA Reductase , Autophagy |
Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemic activity. | |||
T3340 | SCR7 | Apoptosis , DNA/RNA Synthesis , CRISPR/Cas9 | |
T6590 | MK-3207 Hydrochloride | MK-3207 HCl | CGRP Receptor |
MK-3207 Hydrochloride (MK-3207 HCl) is a potent CGRP receptor antagonist with IC50 and Kiof 0.12 nM and 0.022 nM, highly selective versus human AM1, AM2, CTR, and AMY3. Phase 2. | |||
T23535L | Xanthine amine congener trihydrochloride | Xanthine amine congener trihydrochloride (96865-92-8 Free base) | Adenosine Receptor |
Xanthine amine congener trihydrochloride is a potent adenosine antagonist that reverses the reduction in urine flow, sodium excretion and heart rate produced by the adenosine agonist, N6-cyclohexyladenosine. | |||
T7683 | Adenosine amine congener | ADAC | Adenosine Receptor |
Adenosine amine congener (ADAC) (ADAC) is an agonist of selective A1 adenosine receptor,. | |||
T77762 | ROS-generating agent 1 | Apoptosis , Ferroptosis , ROS Kinase | |
Ros-generating agent 1 has anticancer activity and generates ROS by covalently modifying Sec-498 residues of TrxR. ROS-generating agent 1 reduces intracellular TrxR protein levels and promotes ROs-dependent apoptosis and... | |||
T62963 | Xanthine amine congener hydrochloride | ||
Xanthine amine congener (XAC) hydrochloride is a non-selective adenosine receptor antagonist that induces convulsions in mice. | |||
T10122 | Anti-neurodegeneration agent 1 | Others | |
T23535 | Xanthine amine congener | Adenosine Receptor | |
Xanthine amine congener is an Adenosine receptor antagonist. | |||
T74627 | Angiogenesis inhibitor 3 | ||
Angiogenesis Inhibitor 3 (Compound 8) is a potent substance that effectively inhibits the growth of HUVEC and HCT-15 cells, demonstrating IC50 values of 1.00 and 0.71 μM, respectively. It not only induces apoptosis in th... | |||
T13486 | Neurodegenerative Disorder-Targeting Compound 1 | Others | |
Neurodegenerative Disorder-Targeting Compound 1 is an inhibitor of calpain [1]. | |||
T76164 | Lipoxygenase, general | ||
Lipoxygenase (LOX), a dioxygenase, plays a crucial role in biochemistry by catalyzing the transformation of polyunsaturated fatty acids, including linoleic and arachidonic acids, into their respective hydroperoxides [1]. | |||
T75270 | Genevant CL1 | ||
Genevant CL1 is a lipid that can be used for mRNA lipid nanoparticle (LNP) vaccine delivery [1] . | |||
T83527 | (Rac)-Neurodegenerative Disorder-Targeting Compound 1 | ||
(Rac)-Neurodegenerative Disorder-Targeting Compound 1 is a calpain inhibitor. | |||
T83116 | Angiogenesis inhibitor 4 | ||
Angiogenesis Inhibitor 4 is a potent agent for inhibiting angiogenesis, with potential applications in cancer research [1]. | |||
T82458 | Epigenetic factor-IN-1 | Sirtuin | |
Epigenetic factor-IN-1 (40569Z) is an epigenetic factor inhibitor that exhibits potent binding affinity for SIRT7. It is utilized in the study of liver cancer [1]. | |||
T74217 | Angiogenesis agent 1 | HIF/HIF Prolyl-Hydroxylase | |
Angiogenesis Agent 1 (Compound C-31), a glycoside analogue derived from salidroside, acts as an activator of the HIF-1α pathway and shows potential in diabetic hind limb ischemia research [1]. | |||
T39387 | Xanthine amine congener dihydrochloride | XAC dihydrochloride,Xanthine amine congener dihydrochloride | |
Xanthine amine congener dihydrochloride (XAC dihydrochloride), a potent antagonist for both Adenosine A1 and A2 receptors, exhibits IC50 values of 1.8 nM for A1 and 114 nM for A2 receptors. Additionally, it functions as ... | |||
T71722 | Angiogenesis inhibitor BT2 | ||
Angiogenesis inhibitor BT2 is a novel inhibitor of angiogenesis and vascular permeability, inhibiting ERK phosphorylation and the expression of FosB/ΔFosB, VCAM-1, and many genes involved in proliferation, migration, ang... | |||
T72013 | Epigenetic Multiple Ligand | ||
Epigenetic Multiple Ligand is a cell-permeable inhibitor of substrate processing by several chromatin-associated enzymes, including SIRT1/2, H3/SET7, H3/p300/CBP, H4/RmtA, PABP1/CARM1, and H4/PRMT1. It acts by inducing e... | |||
T31425 | Dibenz[a,h]anthracene | CCRIS 208,NSC 22433,AI3-18996,DB(a,h)A | DNA |
Dibenz[a,h]anthracene (CCRIS 208) has induced DNA damage and gene mutations in bacteria and gene mutations and transformation in several types of mammalian cell cultures. | |||
T6696 | Tazarotene | Tazorac,AGN 190168,Zorac | Retinoid Receptor , Autophagy |
Tazarotene (Zorac) is a synthetic, topical retinoid. Tazarotene induces the expression of tazarotene-induced gene 3 (TIG3), a tumor suppressor gene. In psoriasis, tazarotene normalizes abnormal keratinocyte differentiati... | |||
T67839 | HG106 | Others | |
HG106, which is anti-inflammatory and may be used to treat the growth of diseases such as malignant tumours caused by mutations in the RAS gene., which is anti-inflammatory and may be used to treat the growth of diseases... | |||
T60028 | MM41 | DNA/RNA Synthesis | |
MM41 is a human telomeric and gene promoter DNA quadruplex stabilizer with an IC50 of <10 nM against the MIA PaCa-2 pancreatic cancer cell line. | |||
T39965 | NF-κΒ activator 1 | NF-κB | |
NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns. NF-κΒ is widely used in eukaryotic cells as a gene regulating cell proliferation and cell survival. NF-κΒ activator 1 induces superoxide ... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T21205 | Ponasterone A | AI3-44686 | Others |
Ponasterone A (AI3-44686) is an analog of 20-hydroxy ecdysone. Ecdysone has been used to induce mammalian expression systems. | |||
T1426 | Pyrazinamide | Pyrazinoic acid amide,Pyrazinecarboxamide | Antibacterial , Antibiotic , Autophagy , Fatty Acid Synthase |
Pyrazinamide (Pyrazinecarboxamide), an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide derivative. | |||
TN1653 | Fustin | ERK , Beta Amyloid , AChR | |
Fustin is the phytogenic flavanol component of the plant Rhus verniciflua Stokes. Fustin shows protective effects on 6-hydroxydopamine-induced neuronal cell death. | |||
TJS0405 | Lucidin | NSC 30546,Henine | Others |
1. Lucidin (NSC-30546) and its derivatives are genotoxic, it is mutagenic at the hypoxanthine-guanine phosphoribosyl transferase gene locus. | |||
T3919 | Ginsenoside Rb2 | Ginsenoside C | GPR , Others , Influenza Virus , Endogenous Metabolite |
Ginsenoside Rb2 (Ginsenoside C) found in species of Panax, upregulating GPR120 gene expression. | |||
T24729 | Roseoflavin | Antibacterial | |
Roseoflavin, a chemical analog of FMN and riboflavin that has antimicrobial activity, can directly bind to FMN riboswitch aptamers and downregulate the expression of an FMN riboswitch-lacZ reporter gene in B. subtilis. | |||
T6S0214 | Dl-Maackiain | (+)-Maackiain,Demethylpterocarpin | Apoptosis , Parasite |
1. dl-Maackiain (Demethylpterocarpin) induces apoptosis and growth suppression 2. MAK1 is the second functional gene cloned from Maackiain detoxification. | |||
T4461 | 3,5-Diiodo-L-thyronine | Diiodothyronine | Thyroid hormone receptor(THR) , Endogenous Metabolite |
3,5-Diiodo-L-thyronine (Diiodothyronine) is an iodinated thyronine hormone that regulates gene activity affecting processes such as homeostasis, lipid metabolism and insulin resistance. | |||
T6S0325 | Glycitein | Glycetein | Apoptosis , Others |
1. Gycitein has weak estrogenic activity. 2. Glycitein (Glycetein) inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression. | |||
T3524 | Halofuginone hydrobromide | Tempostatin,RU-19110 (hydrobromide),Stenorol | Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad |
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce... | |||
T3406 | Kuromanin chloride | Glucocyanidin chloride,Chrysontemin,Chrysontemin chloride,Cyanidin 3-O-glucoside chloride | NF-κB |
Kuromanin chloride (Chrysontemin chloride) is potent antioxidants and free radical scavengers, may act as modulators of gene regulation and signal transduction pathways. | |||
T19237 | Cholesteryl oleate | Oleoylcholesterol,Cholesterol Oleate,Cholesteryl cis-9-octadecenoate | Endogenous Metabolite |
Cholesteryl oleate (Cholesteryl cis-9-octadecenoate) is a cholesteryl ester. Cholesteryl oleate can be used to synthesize solid lipid nanoparticles which is a nanoparticle-based gene therapy approach. | |||
T3384 | Wedelolactone | IKK Inhibitor II | Apoptosis , NF-κB , Lipoxygenase , Caspase |
Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα. | |||
T41031 | Protamine sulfate | Thrombin | |
Protamine sulfate is a polycationic peptide that serves as an antiheparin agent. This compound can neutralize the anticoagulant action of heparin and enhance lipid-mediated gene transfer. | |||
TN1334 | 7-Methoxyrosmanol | 7-O-Methylrosmanol | cAMP |
7-Methoxyrosmanol (7-O-Methylrosmanol) can effectively suppress FSK-induced luciferase expression under the control of the CRE, PEPCK-C and G6Pase gene promoters, it may contribute to its antihyperglycemic activity. | |||
TN7236 | Cephalandole B | IL Receptor | |
cephalandole B, an indole alkaloid isolated from cyanide, significantly inhibited IL-17A gene expression and suppressed IL-17A luciferase reporter in Jukat cells in a dose-dependent manner. | |||
TN6739 | Angoline | 6-Methoxyldihydrochelerythrine | IL Receptor , STAT |
Angoline (6-Methoxyldihydrochelerythrine) hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor(IC50 : 11.56 μM). It inhibits STAT3 phosphorylation and its target gene expression, and inhibits can... | |||
TMS2182 | Trans-Zeatinriboside | Ribosylzeatin,Zeatin Riboside,Trans-Zeatin Riboside | Others |
trans-Zeatinriboside (Ribosylzeatin) is the most active and ubiquitous form of the naturally occurring cytokinins that promote cell division, stimulate shoot proliferation, inhibit root formation, slow the aging process,... | |||
T19882 | Bryonolic acid | UNII-J7YR6A878I,20-epi-Bryonolic acid | Apoptosis , Antioxidant , Calcium Channel |
Bryonolic acid (20-epi-Bryonolic acid), a triterpenoid extracted from Sandoricum indicum, possesses immunomodulatory, anti-inflammatory, antioxidant and anticancer activities and protects PC12 cells from NMDA-induced apo... | |||
T1034 | Docetaxel | NSC 628503,RP-56976 | Apoptosis , Microtubule Associated , Endogenous Metabolite |
Docetaxel (RP-56976) is a semi-synthetic analog of paclitaxel, a microtubule depolymerization inhibitor (IC50=0.2 μM). Docetaxel attenuates the effects of bcl-2 and bcl-xL gene expression and exhibits apoptosis-inducing,... | |||
T8189 | Dihydroberberine | Potassium Channel , HSP , HER | |
Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities. It inhibits human ether-a-go-go-related gene (hERG) channels and remarkably reduces Hsp90 expression and its interacti... | |||
T7929 | L-Aspartic Acid 4-Benzyl Ester | Others | |
L-Aspartic Acid 4-Benzyl Ester is a chelating agent that forms stable complexes with metal ions. It has been used to study the effect of metal ions on enzyme activity and to investigate the role of metal ions in the regu... | |||
T0603 | Phthalic acid mono-2-ethylhexyl ester | Phthalic Acid Monooctyl Ester | P450 , Endogenous Metabolite |
Phthalic acid mono-2-ethylhexyl ester (Phthalic Acid Monooctyl Ester is a major bioactive metabolite of diethylhexyl phthalate (DEHP), which inhibits the 17, 20 lyase activity of CYP17. Cyp17a1 gene is a specific target ... | |||
T1339 | 5-Azacytidine | Azacitidine,NSC 102816,Mylosar,Ladakamycin,5-AzaC | Nucleoside Antimetabolite/Analog , DNA Methyltransferase , Antibacterial , Antibiotic , Autophagy |
5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity. 5-Azacytidine regulates gene expression by decreasing the level of DNA methylation. 5-Azacytidine induces autopha... | |||
Fr14115 | α-Terpineol | Terpineol | IL Receptor , Anti-infection , Antibacterial |
Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, ... | |||
T3829 | Ginsenoside F3 | Others , IFNAR , Interleukin | |
Ginsenoside-F3 has immunoenhancing activity by regulating production and gene expression of type 1, type 2 cytokines in murine spleen cells. Ginsenoside-F3 enhances the NF-kappaB DNA binding activity induced by ConA in m... | |||
TN2331 | Eleutheroside B1 | Influenza Virus | |
Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits l... | |||
T1429 | 17α-Hydroxyprogesterone | Hydroxyprogesterone,17-OHP,17-Hydroxyprogesterone | Estrogen/progestogen Receptor , Progesterone Receptor , Endogenous Metabolite |
17α-Hydroxyprogesterone (17-OHP) is a physiological progestin that is produced during glucocorticoid and steroid hormone synthesis and is increased during the third trimester of pregnancy. Hydroxyprogesterone binds to th... | |||
T2S2108 | Coixol | 6-methoxybenzoxazolone,6-MBOA,6-Methoxy-2-benzoxazolinone,MBOA | Others , Antibacterial |
1. Coixol (MBOA) acts as a central muscle relaxant with an anti-convulsant effect. 2. Coixol interacts with the pituitary to stimulate reproduction in voles. 3. Coixol has the ability to interact with FSH to stimulate fo... | |||
T0610 | Piceatannol | trans-Piceatannol,Astringenin | Apoptosis , Serine/threonin kinase , PKA , Syk , PKC , Autophagy |
Piceatannol (Astringenin) is an anti-inflammatory, immunomodulatory and antiproliferative agent. It inhibits p56lck and syk protein tyrosine kinases and inhibits NF-κB activation and gene expression of TNF-induced. It is... | |||
T6S2246 | Alisol B 23-acetate | Alisol B Acetate,Alisol B monoacetate,23-O-Acetylalisol B,23-Acetylalismol B | Others |
1. Alisol B 23-acetate (Alisol B Acetate) produces protective effect against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes. 2. Alisol B 23-acetate produces promotiv... | |||
T3676 | Sesamol | 1,3-Benzodioxol-5-ol,3,4-Methylenedioxyphenol | Apoptosis , AMPK |
Sesamol (1,3-Benzodioxol-5-ol) could decrease lung inflammation and lipopolysaccharide (LPS)-induced lung injury in rats. Sesamol ameliorates inflammatory and oxidative damage by upregulating AMPK activation and Nrf2 sig... | |||
T64744 | Ovalbumins | Endogenous Metabolite | |
Ovalbumins is the main protein found in egg whites. Ovalbumins have various biological activities such as antibacterial, anticancer, antihypertensive, antioxidant and immunomodulatory activities. Ovalbumins are the most ... | |||
T6S0525 | Farrerol | ERK , p38 MAPK , Akt | |
1. Farrerol has antioxidative activity.2. Farrerol modulates TAP and BNBD5 gene expression in mammary gland, enhances bMEC defense against S. aureus infection and could be useful in protection against bovine mastitis. 3.... | |||
T3976 | Cytosporone B | Csn-B,Dothiorelone G | Others |
Cytosporone B (Dothiorelone G) is a naturally occurring agonist for the nuclear receptor Nur77 (IC50 = 0.278 nM). Activation of Nur77 with cytosporone B induces the expression of Nur77-dependent genes, including the gene... | |||
T5267 | N-Acetyl-L-glutamic acid | Ac-L-Glu-OH,N-Acetylglutamic acid | Others , Endogenous Metabolite |
N-Acetyl-L-glutamic acid (Ac-L-Glu-OH) (NAcGlu) is an acetylated amino acid. NAcGlu is biosynthesized from glutamic acid and acetyl-CoA by the enzyme N-acetyl glutamate synthase (NAGS). NAcGlu activates carbamoyl phospha... | |||
T4137 | 4,7-DIHYDROXYCOUMARIN | Others | |
4,7-DIHYDROXYCOUMARIN is a naturally occurring coumarin derivative found in a variety of plants, including parsley and chamomile. It has been found to inhibit the activity of several enzymes, including cytochrome P450, c... | |||
TL0008 | Gigantol | Wnt/beta-catenin , Glucosidase | |
Gigantol is a novel inhibitor of the Wnt/β-catenin pathway. It inhibits Wnt/β-catenin signaling through downregulation of phosphorylated LRP6 and cytosolic β-catenin in breast cancer cells. Gigantol may be developed as a... | |||
T4S0878 | Prunetin | Prunusetin | ERK , Dehydrogenase , NF-κB |
1. Prunetin (Prunusetin) significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. 2. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesit... | |||
T25664 | Lepidiline A | Macaline A | Others |
Lepidiline A (Macaline A) is a flavonoid lignin with anti-inflammatory activity. Lepidiline A showed cytotoxic activity against HL-60 cells with IC50 of 32.3 μM. It is the active ingredient of Lepidium meyenii Walpers, a... | |||
T38373 | 2-heptyl-3-hydroxy-4(1H)-Quinolone | 2-heptyl-3-hydroxy-4(1H)-Quinolone,PQS,Pseudomonas Quinolone Signal | Others |
2-heptyl-3-hydroxy-4(1H)-Quinolone (Pseudomonas Quinolone Signal) is a quorum-sensing signalling molecule produced by Pseudomonas aeruginosa in response to increased cell density. It increases the expression of the lasB ... | |||
T37753 | Aureusimine B | Cysteine Protease , Antibacterial | |
Aureusimine B, also known as phevalin, is a natural pyrazinone produced by certain fungi and by Staphylococcus spp., including S. aureus. Its synthesis appears to be initiated by a conserved nonribosomal peptide syntheta... | |||
T13577 | β-Zearalenol | Others | |
β-Zearalenol, a non-steroidal estrogenic mycotoxin synthesized by Fusarium species, potentially influences transcription and affects gene expression on the translational level. | |||
TMA0237 | Carlinoside | Nrf2 | |
Carlinoside could be a worthy choice to intervene hyperbilirubinemia due to liver dysfunction. Carlinoside upregulates Nrf2 gene expression, increases its nuclear translocation and stimulates UGT1A1 promoter activity. | |||
T4S1057 | Tripdiolide | IL Receptor , TNF | |
Tripdiolide has cytotoxic, and anti-rheumatic activities, it suppresses pro-inflammatory gene expression, may be effective therapy for lupus nephritis. | |||
T38561 | Chitopentaose pentahydrochloride | ||
Chitopentaose pentahydrochloride is an anti-inflammatory chitosan oligosaccharide that functions as a substrate for the gene encoding chitinase B (FjchiB). | |||
TN3937 | Ent-16alpha,17-Dihydroxyatisan-3-one | P-gp | |
ent-16alpha,17-Dihydroxyatisan-3-one and ent-16alpha,17-dihydroxykauran-3-one have apoptosis induction activities on L5178 human MDR1 gene-transfected mouse lymphoma cells. | |||
T17270 | Yatein | Others | |
Yatein inhibits herpes simplex virus type 1 replication by interruption the immediate-early gene expression. Yatein is a lignan isolated from A. chilensis. It also has antiproliferative activity. | |||
TN4115 | Gardenine | Others | |
Gardenin has regulatory effect on the gene expression in rats with focal cerebral ischemia. | |||
T68731 | Myxothiazol | ||
Myxothiazol is an inhibitor of mitochondrial respiratory chain complexes III. Myxothiazol induces transcription of the p53-responsive SESN2 gene that plays an important role in stress response and homeostatic regulation. | |||
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カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-05092 | LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His) | Cynomolgus | HEK293 Cells |
LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.4 kDa and the accession number is XP_005570011.1. | |||
TMPY-04730 | LAG-3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
LAG-3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.6 kDa and the accession number is P18627-1. | |||
TMPY-04939 | LAG-3 Protein, Human, Recombinant | Human | HEK293 Cells |
LAG-3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1. | |||
TMPY-03759 | LAG-3 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
LAG-3 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.1 kDa and the accession number is Q5BK54. | |||
TMPJ-00778 | HER2/ERBB2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
HER2/ERBB2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 90-120 KDa and the accession number is P04626. | |||
TMPY-02683 | CSAG1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
CSAG1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.2 kDa and the accession number is Q6PB30-1. | |||
TMPY-05130 | LAG-3 Protein, Human, Recombinant, Biotinylated | Human | HEK293 Cells |
LAG-3 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1. | |||
TMPH-01025 | CALCA Protein, Human, Recombinant (GST) | Human | E. coli |
CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevate... | |||
TMPH-01029 | CAPN1 Protein, Human, Recombinant (His) | Human | E. coli |
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-387' and 'His... | |||
TMPY-04528 | LAG-3 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
LAG-3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 72.9 kDa and the accession number is P18627-1. | |||
TMPY-00027 | GSTT2B Protein, Human, Recombinant (His) | Human | HEK293 Cells |
GSTT2B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29 kDa and the accession number is P0CG29. | |||
TMPY-04731 | LAG-3 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
LAG-3 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 72.6 kDa and the accession number is P18627-1. | |||
TMPY-06931 | LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 Cells |
LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 74.73 kDa and the accession number is NP_002277.4. | |||
TMPY-04611 | LAG-3 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
LAG-3 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 72.1 kDa and the accession number is Q61790. | |||
TMPY-05746 | LAG-3 Protein, Mouse, Recombinant | Mouse | HEK293 Cells |
LAG-3 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.25 kDa and the accession number is Q61790. | |||
TMPY-04612 | LAG-3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
LAG-3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.7 kDa and the accession number is Q61790. | |||
TMPY-01579 | GBA3 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Cytosolic beta-glucosidase, also known as Cytosolic beta-glucosidase-like protein 1, GBA3, CBG and CBGL1 is a cytoplasm protein which belongs to theglycosyl hydrolase 1 family and Klotho subfamily. GBA3 / CBGL1 is a glyc... | |||
TMPJ-01421 | LAG-3 Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 Cells |
LAG-3 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90 KDa and the accession number is XP_005570011.1. | |||
TMPJ-00321 | LAG-3 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
LAG-3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 60-70 KDa and the accession number is P18627. | |||
TMPH-00754 | Capsid decoration Protein, Escherichia phage lambda, Recombinant (GST) | Escherichia phage lambda | E. coli |
Stabilizes the expansion of the capsid head shell after genome packaging. The packaging of viral genome in the procapsid triggers a dramatic reconfiguration of the capsid shell, expanding from roughly 50nm to 60nm while ... | |||
TMPJ-00727 | PGK1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Phosphoglycerate kinase 1(PGK1) is an enzyme. It is mainly expressed in spermatogonia and Localized on the principle piece in the sperm. Its expression significantly decreased in the testis of elderly men. PGK1 involved ... | |||
TMPJ-01362 | UBAP1 Protein, Human, Recombinant (His) | Human | E. coli |
Ubiquitin-Associated Protein 1 (UBAP1) belongs to the UBA domain family. Members of this family are related to ubiquitin and the ubiquitination pathway. Because of their cytogenetic location, this UBA domain family membe... | |||
TMPJ-01177 | NOV/CCN3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
NOV, also called CCN3, is a secreted protein of CCN family members. CCN family members are highly conserved cysteine rich proteins sharing a common modular structure having 4 conserved domains, insulin-like growth factor... | |||
TMPJ-00761 | FTH Protein, Human, Recombinant (His) | Human | E. coli |
Ferritin heavy polypeptide 1(FTH1), is a ubiquitous intracellular protein which stores iron in a soluble, non-toxic, readily available form. FTH1 has ferroxidase activity and is important for iron homeostasis. Iron is ta... | |||
TMPH-01127 | COMMD5 Protein, Human, Recombinant (His) | Human | E. coli |
COMMD5 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-03269 | COMMD5 Protein, Rat, Recombinant (His & Myc) | Rat | E. coli |
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the ... | |||
TMPY-01710 | IkB alpha/NFKBIA Protein, Human, Recombinant (His) | Human | E. coli |
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (IkB alpha, NFKBIA, or IKBA), is a member of the NF-kappa-B inhibitor family that function to inhibit the NF-kB transcription factor. NF... | |||
TMPH-00949 | APOLD1 Protein, Human, Recombinant (His) | Human | E. coli |
May be involved in angiogenesis. May play a role in activity-dependent changes of brain vasculature. May affect blood-brain permeability. APOLD1 Protein, Human, Recombinant (His) is expressed in E. coli expression system... | |||
TMPH-00882 | ACTA2 Protein, Human, Recombinant (His) | Human | E. coli |
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. ACTA2 Protein, Human, Recombinant (His) is expressed in E. coli expression ... | |||
TMPH-01126 | COMMD5 Protein, Human, Recombinant (His & Myc) | Human | Baculovirus Insect Cells |
COMMD5 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus. | |||
TMPJ-00887 | NFKB1 Protein, Human, Recombinant (His) | Human | E. coli |
The 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radica... | |||
TMPJ-00706 | SNCG Protein, Human, Recombinant | Human | E. coli |
Gamma-Synuclein (SNCG) is a member of the Synuclein protein family. Gamma-Synuclein is mostly expressed in the peripheral nervous system and retina. Gamma-Synuclein plays a role in neurofilament network integrity and may... | |||
TMPJ-01292 | Chemerin/RARRES2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Retinoic acid receptor responder protein 2(RARRES2) is a secreted protein that in humans is encoded by the RARRES2 gene. It is highly expressed in skin, also found in pancreas, liver, spleen, prostate, ovary, small intes... | |||
TMPJ-00981 | PTX3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory... | |||
TMPJ-01404 | TMX2 Protein, Human, Recombinant (His) | Human | E. coli |
TMX2 is a single-pass type I membrane protein and contains 1 thioredoxin domain. Thioredoxin plays an important role in various cellular processes through redox regulation. The Molecular Cloning and characterization of ... | |||
TMPJ-00022 | LGALS7 Protein, Human, Recombinant | Human | E. coli |
The Galectin family of proteins, with specificity for Nacetyllactosamine containing glycoproteins, consists of beta-galactoside binding lectins containing homologous carbohydrate recognition domains (CRDs).They also poss... | |||
TMPJ-01032 | SPINK7 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Serine protease inhibitor Kazal-type 7(SPINK7) is a secreted protein, that in humans is encoded by the SPINK7 gene. SPINK7 contains 1 Kazal-like domain. SPINK7 is probably serine protease inhibitor. Recombinant human SPI... | |||
TMPJ-00111 | CD9 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
CD9, also known as Tspan29, 5H9 antigen, Leukocyte antigen MIC3 (MIC3), Motility-related protein, is a multi-pass membrane protein which belongs to the tetraspanin (TM4SF) family or the transmembrane 4 superfamily. CD9 i... | |||
TMPH-00963 | Ataxin-2 Protein, Human, Recombinant (His) | Human | E. coli |
Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane. Ataxin-2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. ... | |||
TMPH-01299 | EMC4 Protein, Human, Recombinant (His) | Human | E. coli |
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. Preferentially accommodates prot... | |||
TMPJ-01121 | MORF4L2 Protein, Human, Recombinant (His) | Human | E. coli |
Mortality Factor 4-Like Protein 2 (MORF4L2) is a member of the mortality factor (MORF) family. MORF4L2 localizes in the nucleus, possessing a protein kinase C phosphorylation site and a tyrosine phosphorylation site. MOR... | |||
TMPH-01098 | ACOD1 Protein, Human, Recombinant (His) | Human | E. coli |
ACOD1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 58.6 kDa and the accession number is A6NK06. | |||
TMPH-02585 | ACOD1 Protein, Mouse, Recombinant (His & Myc) | Mouse | Baculovirus Insect Cells |
Cis-aconitate decarboxylase that catalyzes production of itaconate and is involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory inna... | |||
TMPJ-00724 | LDHA Protein, Human, Recombinant (His) | Human | E. coli |
L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region,... | |||
TMPH-01901 | DDX53 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
N/A. DDX53 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 76.2 kDa and the accession number is Q86TM3. | |||
TMPJ-00777 | HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc) | Human | HEK293 Cells |
HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 120-145 KDa and the accession number is P04626. | |||
TMPJ-00776 | HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 Cells |
HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 120-140 KDa and the accession number is P04626. | |||
TMPJ-01319 | TINAGL1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
TINAGL1 is a secreted protein and contains one SMB (somatomedin-B) domain. TINAGL1 is expressed in aorta, lymph nodes, heart, bone marrow, placenta, lung, kidney, skeletal muscle, pancreas, thyroid, adrenal gland and so ... | |||
TMPH-02557 | CAPN1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-388' and 'His... | |||
TMPH-00350 | Adiponectin Protein, Feline, Recombinant | Feline | E. coli |
Adiponectin Protein, Feline, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 24.9 kDa and the accession number is A4PB30. | |||
------------------------ More ------------------------ |
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Well-chosen 953 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new drugs; | |||
L7700 | Neural Regeneration Compound Library | 524 compounds | |
A unique collection of 149 neuroregeneration related compounds for high throughput and high content screening; | |||
L7900 | Osteogenesis Compound Library | 317 compounds | |
A unique collection of 317 osteogenesis related compounds for high throughput and high content screening; | |||
L2620 | Anti-Neurodegenerative Disease Compound Library | 2154 compounds | |
A unique collection of 2154 compounds related to neurodegenerative diseases can be used for HTS or HCS; | |||
L4800 | Angiogenesis related Compound Library | 1353 compounds | |
A unique collection of 1353 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS); | |||
L3510 | Methylation Compound Library | 128 compounds | |
128 methylation-related compounds that can be used for high-throughput and high-content screening. | |||
L3800 | NF-κB Signaling Compound Library | 729 compounds | |
A unique collection of 729 compounds targeting NF-κB signaling for high throughput screening and high content screening; | |||
L3500 | Histone Modification Compound Library | 469 compounds | |
A unique collection of 469 histone modification related compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L6001 | Mini Fungal Metabolite Natural Product Screening Library | Inquiry | |
L3600 | Cytokine Inhibitor Library | 604 compounds | |
A unique collection of 604 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery; | |||
L5400 | Anti-Cardiovascular Disease Compound Library | 1408 compounds | |
A unique collection of 1408 cardiovascular diseases related compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L8200 | Anti-Aging Compound Library | 3279 compounds | |
A unique collection of 3279 anti-aging compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L8300 | Chromatin Modification Compound Library | 250 compounds | |
A unique collection of 250 compounds targeting chromatin remodeling pathway for high throughput screening (HTS) and high content screening (HCS); | |||
L2140 | Cancer Cell Differentiation Compound Library | 406 compounds | |
A unique collection of 406 cancer cell differentiation inducing compounds for high throughput and high content screening; | |||
L7200 | Calcium Channel Compound Library | 140 compounds | |
A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening; | |||
L9500 | Target-Focused Phenotypic Screening Library | 1796 compounds | |
A unique collection of 1796 annotated bioactive compounds with clear targets, suitable for phenotypic screening; | |||
L8500 | HIF-1 Signaling Pathway Compound Library | 1336 compounds | |
A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies; |