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カタログ番号 | 製品名 | 別名 | ターゲット |
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T5051 | Isopropamide Iodide | AChR | |
Isopropamide iodide is a long-acting anticholinergic drug. It is used in the treatment of peptic ulcers and other gastrointestinal disorders. It also acts as a muscarinic receptor antagonist which can be applied to the t... | |||
T4981 | Anisotropine Methylbromide | Prostaglandin Receptor , AChR | |
Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion. | |||
T1460 | Dicyclomine hydrochloride | AChR | |
Dicyclomine hydrochloride is a muscarinic antagonist used as an antispasmodic and in urinary incontinence. | |||
T9353 | OXOMEMAZINE | AChR , Histamine Receptor | |
Oxomemazine is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic activity. Oxomemazine is a selective antagonist of mycotoxins M1 receptors, showing high (Ki=84 nM, M1 receptors) and low ... | |||
T22380 | Nor-benzetimide | Others , AChR | |
Norbenzetimide, an organic compound, is prepared from benzetimide by catalytic transfer hydrogenolysis. | |||
T5023 | Propiverine hydrochloride | Others , Calcium Channel , AChR | |
Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB). | |||
T0023 | Valethamate bromide | Ediposin,Epidozin,Epidosin,Resitan | Others |
Valethamate bromide (Resitan) is an anticholinergic agent that has antispasmodic effects and inhibits glandular secretion. | |||
T16472 | Pericyazine | Propericiazine,RP 8909 | Dopamine Receptor |
Pericyazine (Propericiazine) is a selective D2-dopamine receptor antagonist. Pericyazine is a first-generation antipsychotic drug that is used as an adjunct to the short-term management of severe anxiety states and psych... | |||
T1472 | Trospium chloride | Spasmex,Sanctura | AChR |
Trospium chloride (Spasmex) is an antispasmodic and anticholinergic agent used to treat urinary incontinence and overactive bladder syndrome. Trospium chloride has not been implicated in causing liver enzyme elevations o... | |||
T28827 | Sofpironium bromide | BBI4000,BBI 4000,BBI-4000 | Others , AChR |
Sofpironium bromide (BBI4000) belongs to a class of drugs called anticholinergics, which exert their effect by blocking the action of acetylcholine. | |||
T1072 | Loxeen | Pridinol methanesulfonate | AChR |
Loxeen (Pridinol methanesulfonate) is used as an anticholinergic and as an antiparkinsonian agent. | |||
T4979 | Procyclidine hydrochloride | (±)-Procyclidine hydrochlorid | NMDAR , iGluR |
Procyclidine hydrochloride ((±)-Procyclidine hydrochlorid) is a potent anticholinergic agent and also have NMDA antagonist properties. | |||
T1336 | Benztropine mesylate | Benzotropine mesylate,Benzatropine mesylate,Benztropine methanesulfonate | Dopamine Receptor , AChR , Histamine Receptor |
Benztropine mesylate (Benztropine methanesulfonate) is a centrally active muscarinic antagonist that has been used in the symptomatic treatment of PARKINSON DISEASE. Benztropine also inhibits the uptake of dopamine. | |||
T1567 | Olanzapine | LY170053 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR |
Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness. | |||
T0205 | Brompheniramine maleate | Dimotane,Rolabromophen,Brompheniramine hydrogen maleate,Dimetane | 5-HT Receptor , Histamine Receptor |
Brompheniramine maleate (Dimotane) is an antagonist against histamine H1 receptors. | |||
T0218 | Biperiden | Bipariden,Akineton,KL 373,Biperidine | AChR |
Biperiden (Bipariden) is a muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. ... | |||
T13118 | Temiverine hydrochloride | Calcium Channel | |
Temiverine hydrochloride is a potential calcium channel antagonist with anticholinergic effects that inhibits some of the functions of atropine. | |||
T10732 | Tematropium | CDDD3602,Tematropium metilsulfate,HGP6 | AChR |
Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies. | |||
T21014 | Thonzylamine hydrochloride | Resistab,Thonzylamine HCl,Novohetramin,Neohetramine hydrochloride,Anahist | AChR , Histamine Receptor |
Thonzylamine hydrochloride (Resistab) is an anticholinergic and antihistamine used as an antipruritic. | |||
T7477 | Antazoline | Others | |
Antazoline has antihistamine and anticholinergic effects.It used to treat a variety of arrhythmias. | |||
T7564 | Chlorphenoxamine | Contristamine | Histamine Receptor |
Chlorphenoxamine (Contristamine) is an antihistamine and anticholinergic used as an antipruritic and antiparkinsonian agent. | |||
T0147 | Clemastine fumarate | HS-592 (fumarate),Meclastine fumarate,Meclastine (fumarate) | Autophagy , Histamine Receptor |
Clemastine fumarate (Meclastine (fumarate)) is a synthetic ethanolamine with anticholinergic, sedative, and histamine H1 antagonistic properties. | |||
T68082 | Glycopyrronium tosylate | ||
Glycopyrronium tosylate an anticholinergic compound used in the treatment of axillary hyperhidrosis for the study of a variety of cryptobacterial tumors. | |||
T31488 | Dimethindene | Dimetindeno,Z 2001,Dimetindene,Z-2001,Z2001 | Potassium Channel , Endogenous Metabolite , AChR , Histamine Receptor |
Dimethindene (Dimetindeno) is a selective antagonist of H1 receptor and blocks K+ current. Dimethindene exhibits antihistamine and anticholinergic effects. | |||
T35033 | Vamicamide | FK 176,FK-176,FK176 | AChE |
Vamicamide (FK 176) is a novel anticholinergic compound. Vamicamide increases spontaneous locomotor activity in mice at 32 mg/kg (p.o.) or higher and inhibits cataleptic convulsions in mice at 100 mg/kg. | |||
T1049L | Oxybutynin | Oxytrol,Ditropan,Oxibutyninum | Potassium Channel , AChR |
Oxybutynin (Ditropan) is a synthetic anticholinergic agent that is used for treatment of urinary incontinence and overactive bladder syndrome. | |||
T33846 | Oxyphenonium bromide | Spasmophen,Oxifenon,Oxyfenon,Atrenyl,Oxyphenon | Others |
Oxyphenonium bromide (Oxyfenon) shows anticholinergic activity and can be used for research on the treatment of gastric and duodenal ulcers and for the relief of visceral spasms. | |||
T0594 | Diphenmanil methylsulfate | Diphemanil mesylate,Diphemanil Methylsulfate | AChR |
Diphenmanil methylsulfate (Diphemanil mesylate), a quaternary ammonium anticholinergic, binds muscarinic acetylcholine receptors and thus decreases secretory excretion of stomach acids, sweat, and saliva. | |||
T6547 | Ipratropium Bromide | Sch 1000,Itrop,Atrovent | AChR |
Ipratropium Bromide (Sch 1000) is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis and emphysema. | |||
T1049 | Oxybutynin chloride | Oxybutynin hydrochloride,Oxybutynin HCl | Potassium Channel , AChR |
Oxybutynin chloride (Oxybutynin HCl) is an anticholinergic medication used to relieve urinary and bladder difficulties. It competitively antagonizes the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor. | |||
T61233 | Penehyclidine hydrochloride | Penequinine hydrochloride | NF-κB , AChR |
Penehyclidine hydrochloride (Penequinine hydrochloride) is an M1 and M3 antagonist and activates NF-κB in lung tissue. Penehyclidine hydrochloride inhibits the release of inflammatory factors and shows anticholinergic pr... | |||
T21419 | Diphenhydramine | Debendrin,PM 255,PM255,Dabylen,Syntedril,PM-255 | Histamine Receptor |
Diphenhydramine (Syntedril), a first-generation antihistamine possessing antiemetic, antitussive, anticholinergic, and sedative properties, is mainly used in the treatment of allergies. Diphenhydramine is also used in th... | |||
T0785 | Dexchlorpheniramine Maleate | S-(+)-Chlorpheniramine maleate salt | Dopamine Receptor , 5-HT Receptor , Norepinephrine , Histamine Receptor |
Dexchlorpheniramine Maleate (S-(+)-Chlorpheniramine maleate salt) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria. It is the pharmacologically active d... | |||
T0776 | Phenothiazine | ENT 38 | Dopamine Receptor , Antibacterial , Antibiotic , Antifungal |
Phenothiazine (ENT 38) is a class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Phenothiazines antagonize the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ)... | |||
T17210L1 | (3R,6R)-Vaborbactam | (3R,6R)-RPX7009,(3R,6R)-Vaborbactam (Iso-1360457-46-0) | Antibacterial |
(3R,6R)-Vaborbactam ((3R,6R)-Vaborbactam (Iso-1360457-46-0)) is a cyclic boronic acid pharmacophore β-lactamase inhibitor with potential antimicrobial activity. (S)-Vamicamide ((S)-Vamicamide (Iso-132373-81-0)) is a nove... | |||
T35033L | (S)-Vamicamide | (S)-Vamicamide (Iso-132373-81-0) | AChE |
(S)-Vamicamide is a novel anticholinergic compound.Vamicamide increases spontaneous locomotor activity in mice at 32 mg/kg or higher (p.o.) and inhibits tonic convulsions in mice at 100 mg/kg.CAS 번호13483-86-1 | |||
T77678 | TZ3O | AChR | |
TZ3O is an anticholinergic compound with neuroprotective activity.TZ3O ameliorates memory impairment and cognitive decay in Scopolamine-induced Alzheimer's type model in rats, and can be used in the study of Alzheimer's ... | |||
T4563 | Thonzylamine | neohetramine | Histamine Receptor |
Thonzylamine (neohetramine) is an antihistamine and anticholinergic drug. It is available as combination products with Clofedanol or Phenylephrine for temporary relief of symptoms of common cold, hay fever (allergic rhin... | |||
T2555 | Aclidinium bromide | LAS 34273,LAS-W 330 | AChR |
Aclidinium bromide (LAS-W 330) is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis or emphysema. Aclidinium has not been implicated in causing li... | |||
T0059 | Diphenylpyraline hydrochloride | 4-Diphenylmethoxy-1-methylpiperidine hydrochloride | Histamine Receptor |
Diphenylpyraline hydrochloride (4-Diphenylmethoxy-1-methylpiperidine hydrochloride) is used in the treatment of Parkinsonism.It is a first-generation antihistamine with anticholinergic effects, functions as a dopamine re... | |||
T15044 | D609 | Apoptosis , Antioxidant | |
D609 (Tricyclodecan-9-yl-Xanthogenate) has a wide range of biological activities including antioxidant, antiapoptotic, anticholinergic, antitumor, anti-inflammatory, antiviral, antiproliferative, and neuroprotective acti... | |||
T21673 | N-Isopropylnoratropine | Others | |
N-Isopropylnoratropine is a noratropine derivative and an intermediate in the production of ipratropium, an atropine-like bronchodilator drug via an anticholinergic pathway. N-Isopropylnoratropine is used to examine the ... | |||
T1179 | Tiotropium bromide | Tiopropium,BA679 BR | AChR |
Tiotropium bromide (BA679 BR) is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). Tiotropium is a muscarinic receptor antagonist, on topical a... | |||
T0204 | Protriptyline hydrochloride | Protriptyline HCl | 5-HT Receptor , AChE |
Protriptyline Hydrochloride is the hydrochloride salt form of protriptyline, a tricyclic secondary amine with an antidepressant property. Protriptyline hydrochloride (Protriptyline HCl) blocks the re-uptake of norepineph... | |||
T1540 | Doxepin hydrochloride | Toruan,Doxepin HCl,Aponal,Novoxapin | P450 , Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR , Norepinephrine , Histamine Receptor |
Doxepin hydrochloride (Aponal) is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it ap... | |||
TQ0304 | Metixene hydrochloride hydrate | AChR | |
T0089 | Cetirizine dihydrochloride | P071,UCB P071,Cetirizine DiHCl | Histamine Receptor |
Cetirizine dihydrochloride (UCB P071) is an effective second-generation histamine H1 antagonist that is potent in the therapy of allergic rhinitis, confirmed urticaria, and pollen-induced asthma. Unlike other conventiona... | |||
T0786 | Clidinium bromide | Ro 2-3773 | AChR |
Clidinium bromide (Ro 2-3773) , a synthetic anticholinergic agent, has been shown in experimental and clinical researchers to have a pronounced antisecretory and antispasmodic effect on the gastrointestinal tract. It can... | |||
T1278 | Astemizole | Laridal,Histaminos,Paralergin | Potassium Channel , Histamine Receptor |
Astemizole (Laridal) is a synthetic piperidinyl-benzimidazol derivative with antiallergic properties, acts as a reversible competitive inhibitor of histamine H1 receptors, with less anticholinergic effects compared to re... | |||
T1442 | Pizotifen | Pizotyline,BC-105 | 5-HT Receptor |
Pizotifen (Pizotyline) is a strong serotonin and tryptamine antagonist, with weak anticholinergic, anti-histaminic and anti-kinin effects. It also possesses sedative and appetite-stimulating properties. Pizotifen hydroch... |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T5595 | Tropine | 3alpha-Tropanol,Pseudotropine | Others |
Tropine is a naturally-occurring tropane alkaloid extracted primarily from plants of the Solanaceae family. It serves as an intermediate in the synthesis of a variety of bioactive alkaloids. | |||
T8304 | Anisodamine Hydrobromide | 6-Hydroxyhyoscyamine | Adrenergic Receptor , AChR |
Anisodamine Hydrobromide (6-Hydroxyhyoscyamine) is an anticholinergic and α1-adrenergic receptor antagonist used in the treatment of acute circulatory shock. | |||
T0970 | Racanisodamine | Anisodamine,7β-Hydroxyhyoscyamine,Raceanisodamine | Adrenergic Receptor , AChR |
Racanisodamine (7β-Hydroxyhyoscyamine) is an anticholinergic and α1-adrenergic receptor antagonist used in the treatment of acute circulatory shock. | |||
T3341 | Elemicin | Elemicine,3,4,5-trimethoxyallylbenzene | Influenza Virus , 5-HT Receptor , Stearoyl-CoA Desaturase (SCD) |
Elemicin (Elemicine) is a constituent of several plant species' essential oils with anticholinergic effects in human. | |||
TN4883 | Quinine sulfate dihydrate | Others | |
Quinine sulfate dihydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassiu... | |||
T4S1619 | L-Hyoscyamine sulfate | Hyoscyamine sulfate hydrate,Levsin Sulfate,Hyoscyamine Sulphate | AChR |
L-Hyoscyamine sulfate (Levsin Sulfate) is the sulfate salt of a belladonna alkaloid derivative and the levorotatory form of racemic atropine isolated from the plants Hyoscyamus niger or Atropa belladonna, which exhibits ... | |||
T0962 | L-Hyoscyamine | Daturine,Hyoscyamine | AChR |
L-Hyoscyamine (Daturine) functions as a non-selective, competitive antagonist of muscarinic receptors, thereby inhibiting the parasympathetic activities of acetylcholine on the salivary, bronchial, and sweat glands, as w... | |||
T13158 | Tigloidin | Tiglyssin,Tigloyl pseudotropine,Tiglylpseudotropine | Others |
Tigloidin is an atropine analog with anticholinergic activity. | |||
T75691 | Amaroswerin | ||
Amaroswerin, a bioactive secoiridoid glucoside derived from Swertia mussotii, exhibits anti-inflammatory, antidiabetic, antiviral, anticholinergic, and immunomodulatory properties. It notably inhibits nitric oxide (NO) r... |