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T60917 |
Dopamine D4 receptor antagonist-1
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Dopamine D4 receptor antagonist-1 can be used in schizophrenia study. Dopamine D4 receptor antagonist-1 is a selective antagonist of Dopamine D4 receptor (DRD4). The Ki value of Dopamine D4 receptor antagonist-1 for Hd4.... |
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T22019 |
ABT 724 trihydrochloride
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Dopamine Receptor
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ABT 724 trihydrochloride is an effective and selective agonist of the D4 receptor (EC50 = 12.4 nM, 14.3 nM, and 23.2 nM for human, rat and ferret, respectively). ABT-724 trihydrochloride can be used in erectile dysfuncti... |
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T7834 |
ABT-724
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Dopamine Receptor
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ABT-724 is an agonist of dopamine D4 receptor(EC50: 12.4 nM) |
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T22904 |
L-745870 trihydrochloride
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L-745,870 trihydrochloride |
Dopamine Receptor
,
Sigma receptor
,
5-HT Receptor
,
Adrenergic Receptor
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L-745870 trihydrochloride is a highly potent and selective D4 dopamine receptor antagonist. |
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T12383 |
PD 168568 dihydrochloride
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PD 168568 (dihydrochloride) |
Dopamine Receptor
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PD 168568 dihydrochloride (PD 168568 (dihydrochloride)) is an orally active and selective antagonist of D4 dopamine receptor(Ki of 8.8 nM). |
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T12761 |
Ro 10-5824 dihydrochloride
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Dopamine Receptor
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Ro 10-5824 dihydrochloride is a selective agonist of dopamine D4 receptor partial, (Ki of 5.2 nM). |
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T15270 |
Fananserin
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RP 62203 |
Dopamine Receptor
,
5-HT Receptor
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Fananserin is an orally bioavailable and selective antagonist of the 5-HT2 receptor (Ki: 0.37 nM for the rat 5-HT2A receptor). It also is an antagonist of dopamine D4 receptor (Ki: 2.93 nM for the human dopamine D4 recep... |
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T10213 |
A-437203
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ABT-925,A37203,Lu201640 |
Dopamine Receptor
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A-437203 (Lu201640) is A kind of based on 1 h - pyrimidin - 2 - one sca ff old, selective, new powerful d3 receptor antagonist, on D2, d3, and D4 receptor, Ki value 71, respectively 1.6 and 6220 nM. |
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T27979 |
Masilukast
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ICI-D-3523,ZD-3523,ICI D-3523,MCC-847,SA-09012,D-3523 |
Leukotriene Receptor
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Masilukast(MCC-847) is an oral leukotriene D4 (LTD4) receptor antagonist for the study of diseases associated with inflammation. |
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T5047 |
PD-168077 maleate
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Dopamine Receptor
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PD-168077 maleate is a selective agonist of dopamine D4 receptor(Ki : 9 nM) |
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T11799 |
L-745870 hydrochloride
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Dopamine Receptor
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L-745870 hydrochloride has excellent brain penetration. L-745870 hydrochloride is a high-affinity, selective and orally active human dopamine D4 receptor antagonist with a Ki of 0.43 nM, and considerably weaker D2 recept... |
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T27060 |
CP-226269
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CP 226269,CP226269 |
Dopamine Receptor
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CP-226269 is a potent dopamine D4 receptor agonist that regulates calcium flux and has an EC50 value of 32.0 nM. CP 226269 can be used to study neurological disorders such as schizophrenia. |
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T23066 |
NGD 94-1
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Dopamine Receptor
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NGD 94-1 is a selective D4 receptor antagonist with an affinity of 3 nM for the D4 receptor and greater than 2 pM for the D1, D2, D3, and D5 receptors.NGD 94-1 can be used in the study of cognitive disorders and other ps... |
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T12480 |
Pipamperone
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Floropipamide,McN-JR 3345,R 3345 |
Others
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Dopamine Receptor
,
5-HT Receptor
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Pipamperone (McN-JR 3345) binds 5-HT2A closely as receptor. |
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T5397 |
A-381393
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Dopamine Receptor
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A-381393 is a selective and brain penetrate dopamine D4 receptor antagonist (Kis: 1.9/1.5/1.6 nM for human dopamine D4.2/D4.4/D4.7 receptor). |
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T24055 |
FAUC 213
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FAUC213,FAUC-213 |
Dopamine Receptor
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FAUC 213 is a selective full antagonist of the dopamine D4 receptor. |
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T2631 |
WAY-100635 Monomaleate
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Dopamine Receptor
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5-HT Receptor
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WAY-100635 maleate is a selective 5-hydroxytryptamine 1A receptor antagonist with an IC50 value of 0.91 nM and a Ki value of 0.39 nM. It is also a dopamine D4 receptor agonist with pIC50 values of 8.9 and 6.6 for 5-HT1A ... |
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T5158 |
N-Desmethylclozapine
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Desmethylclozapine,Normethylclozapine,Norclozapine |
Virus Protease
,
Dopamine Receptor
,
5-HT Receptor
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Opioid Receptor
,
AChR
,
Drug Metabolite
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N-Desmethylclozapine (Desmethylclozapine) is an antagonist of serotonin (5-HT) receptor subtype 5-HT2C (IC50: 7.1 nM). It also is an antagonist at dopamine D4 receptors, an agonist at δ-opioid receptors. |
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T30098 |
Aplindore Fumarate
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Aplindore,DAB-452 Fumarate,DAB-452 |
Dopamine Receptor
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5-HT Receptor
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Adrenergic Receptor
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Aplindore Fumarate (DAB-452) is a small molecule dopamine D2 receptor partial agonist.Aplindore Fumarate exhibits high affinity for dopamine D2 and D3 receptors, and low affinity for dopamine D4, 5-hydroxytryptophan (5-H... |
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T31602 |
Ecopipam
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Sch-39166,UNII-0X748O646K,Sch 39166 |
Dopamine Receptor
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Ecopipam (UNII-0X748O646K) is a potent, selective and orally active antagonist of dopamine D1/D5 receptor, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam shows more than 40-flod selectivity over D2, D4, 5-HT, and ... |
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T14767 |
BP 897 hydrochloride
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Dopamine Receptor
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BP 897 is a potent and selective agonist of dopamine D3 receptor and it is a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 and D2 receptors. Which shows low affinities at D1 and D4 receptors ... |
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T28167 |
NGB 2904
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NGB2904 HCl,NGB-2904,NGB2904 |
Others
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Dopamine Receptor
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5-HT Receptor
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NGB 2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively). NGB2904 potently antag... |
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T9100 |
BP 897
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2-Naphthalenecarboxamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]- |
Dopamine Receptor
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BP 897 (2-Naphthalenecarboxamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-) is a potent and selective dopamine D3 receptor agonist, and a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 ... |
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T6736 |
Zafirlukast
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Vanticon,ICI 204219,Accolate |
Leukotriene Receptor
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Zafirlukast (ICI 204219) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma. |
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T1476 |
Pramipexole
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SND 919 |
Dopamine Receptor
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Pramipexole (SND 919) is a selective dopamine receptor agonist used in the therapy of Parkinson disease. Pramipexole therapy is associated with a low rate of transient serum enzyme elevations during treatment but has not... |
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T11463 |
GR 103691
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Dopamine Receptor
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GR 103691 is a potent, selective dopamine D3 receptor antagonist (Ki: 0.4 nM). It shows more than 100-fold selectivity for human dopamine human (h)D3 over hD4 and hD1 sites. |
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T3148 |
MK-571 sodium
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L-660711 (sodium salt),L-660711 sodium salt,Verlukast sodium,L-660711,MK571,MK-571 sodium salt,Propanoic acid |
Leukotriene Receptor
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LTR
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MK-571 sodium (L-660711 sodium salt) is a selective, orally active antagonist of the CysLT1 receptor. MK-571 sodium is a multidrug resistance protein-2 (ABCC2, Mrp2) inhibitor used to demonstrate the role of Mrp2 in the ... |
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T1539 |
Iloperidone
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HP 873 |
Dopamine Receptor
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5-HT Receptor
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Adrenergic Receptor
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Iloperidone (HP 873) is an atypical antipsychotic agent that is used for treatment of schizophrenia. |
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T23380 |
Sonepiprazole
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Dopamine Receptor
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Sonepiprazole (PNU-101387G) is a chemical compound known for its selective antagonistic properties toward D4 dopamine receptors, exhibiting dissociation constants (Kis) of 3.6 nM and 10.1 nM for rat D4 (rD4) and human D4... |
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T7635L |
Raclopride tartrate
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FLA 870,FLA-870,FLA870 |
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Raclopride is a selective antagonist on D2 dopamine receptor ( D2 Ki: 1.8 nm, D3 Ki: 3.5 nm, D4 Ki: 2400, D1 Ki: 18000 nM). |
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T12252 |
NRA-0160
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Dopamine Receptor
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NRA-0160 is a selective antagonist of dopamine D4 receptor(Ki of 0.48 nM) |
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T27777 |
L-750,667 TriHydrochloride
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L 750,667,L750,667,L-750,667 |
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L-750,667 TriHydrochloride is a selective antagonist of D4 dopamine receptor. |
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T27063 |
CP-293019
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CP293019 |
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CP-293019 is a potent, selective antagonist of dopamine D4 receptor. |
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T69466 |
FAUC-299
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FAUC-299 is a dopamine D4 receptor agonist. |
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T11799L |
L-745870
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Dopamine Receptor
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L-745870 is a high-affinity and selective human dopamine D4 receptor antagonist (Ki: 0.43 nM). L-745870 has excellent brain penetration. It considerably weaker D2 (Ki: 960 nM) and D3 (Ki: 2300 nM) receptors affinity. |
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T6951 |
Pramipexole dihydrochloride hydrate
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Pramipexole 2HCl Monohydrate,Mirapex |
Dopamine Receptor
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Pramipexole dihydrochloride hydrate (Mirapex) is the hydrochloride salt of pramipexole, a benzothiazole derivative. As a nonergot dopamine agonist, pramipexole binds to D2 and D3 dopamine receptors in the striatum and su... |
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T26360L |
Benperidol Hydrochloride
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Benperidol Hydrochloride is a potent D2/D4 dopamine receptor antagonist, used as antipsychotic and neuroleptic. |
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T10946 |
D4-abiraterone
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Abiraterone D4A metabolite,CB-7627,Δ4-Abiraterone |
Androgen Receptor
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D4-Abiraterone is an inhibitor of CYP17A1, 3b-hydroxysteroid dehydrogenase (3βHSD) and steroid 5a-reductase (SRD5A), the main metabolite of abiraterone. D4-Abiraterone is also an antagonist of androgen receptor. |
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T23170 |
PNU-96415E
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PNU 96415E |
Others
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dopamine D4 and serotonergic 5-HT2A receptor antagonist |
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T24304 |
L 648051
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4-Apsob,L48051,L-648051 |
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L 648051 is a leukotriene D4 receptor antagonist. |
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T19691 |
A412997
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A412997 is a selective agonist of dopamine D4 receptor. |
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T14088 |
ABT-670
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Dopamine Receptor
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T25407 |
FAUC-113
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FAUC113 |
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FAUC-113 is an antagonist of Dopamine D4 receptor. |
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T27893 |
LY 203647
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LY203647,LY-203647 |
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LY 203647 is a antagonist of leukotriene D4 and E4 receptor. |
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T22903 |
L-741,742 hydrochloride
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Others
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L-741,742 hydrochloride is a highly potent and selective D4 dopamine receptor antagonist. |
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T11197 |
Enclomiphene D4 hydrochloride
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(E)-Clomiphene D4 hydrochloride,Enclomifene D4 hydrochloride,trans-Clomiphene D4 hydrochloride |
Others
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Enclomiphene D4 hydrochloride ((E)-Clomiphene D4 hydrochloride; trans-Clomiphene D4 hydrochloride; Enclomifene D4 hydrochloride) is a potent and orally active oestrogen receptor antagonist, with antioestrogenic property... |
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T28505 |
RBI-257 Maleate
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RBI257 Maleate,p-Iodo-U-101958 Maleate,RBI 257 Maleate,p-Iodo U-101958 Maleate |
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RBI-257 Maleate is a highly potent selective ligand of dopamine D4 receptor. |
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T24056 |
FAUC-312
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FAUC 312 |
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FAUC-312 is a potent and selective agonist of the dopamine D4 receptor. |
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T24358 |
L 741742 (free base)
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L-741,742,L-741742,L 741742,L 741,742,L741742 |
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L 741742 is an effective and highly selective antagonist of the D4 dopamine receptor (Ki: 1700, 770, and 3.5 nM at cloned human D2, D3, and D4 receptors). |
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T69095 |
FAUC-179
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FAUC-179 is a selective dopamine D4 receptor partial agonist. |
