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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T3186 | NU2058 | O6-(Cyclohexylmethyl)guanine,O(6)-Cyclohexylmethylguanine | Topoisomerase , CDK |
NU2058 (O(6)-Cyclohexylmethylguanine) is a guanine-based CDK inhibitor, also inhibits DNA topoisomerase II ATPase activity. | |||
T29689 | AFB1-N7-guanine | ||
In epidemiological studies, Aflatoxin B1-N7-guanine serum albumin adducts have been established as biomarkers of dietary aflatoxin exposure. | |||
TNU1326 | N-Trityl-morpholino guanine | ||
N-Trityl-morpholino guanine is a Nucleoside Derivative - Morpholino nucleoside. | |||
TNU0267 | 9-(b-D-Xylofuranosyl)guanine | ||
9-(b-D-Xylofuranosyl)guanine is a Nucleoside Derivative - Xylo-nucleoside. | |||
TNU1437 | (S)-9-(2,3-Dihydroxypropyl)-guanine | ||
(S)-9-(2,3-Dihydroxypropyl)-guanine is a Nucleoside Derivative - Acyclic nucleoside. | |||
TNU0794 | N2-acetyl-O6-(diphenylcarbamoyl)guanine | ||
N2-acetyl-O6-(diphenylcarbamoyl)guanine is a useful organic compound for research related to life sciences. The catalog number is TNU0794 and the CAS number is 112 233-74-6. | |||
TNU0891 | N2-Boc-guanine-9-acetic acid | ||
N2-Boc-guanine-9-acetic acid is a PNA-related Derivative; PNA monomer. | |||
TNU0384 | 8-Benzyloxy-9-(b-D-xylofuranosyl)guanine | ||
8-Benzyloxy-9-(b-D-xylofuranosyl)guanine is a Nucleoside Derivative - Xylo-nucleoside; 8-Modified purine nucleoside. | |||
TNU1438 | N2-Isobutyryl-(S)-9-(2,3-dihydroxypropyl)-guanine | ||
N2-Isobutyryl-(S)-9-(2,3-dihydroxypropyl)-guanine is a Nucleoside Derivative - Acyclic nucleoside. | |||
TNU1327 | 7’-t-Butyldimethylsilyloxy-N-trityl-morpholino guanine | ||
7'-t-Butyldimethylsilyloxy-N-trityl-morpholino guanine is a Nucleoside Derivative - Morpholino nucleoside. | |||
TNU0382 | 8-Bromo-9-(b-D-xylofuranosyl)guanine | ||
8-Bromo-9-(b-D-xylofuranosyl)guanine is a Nucleoside Derivative - Xylo-nucleoside; 8-Modified purine nucleoside. | |||
TNU1589 | N2-Isobutyryl-7’-OH-N-DMTr-morpholino guanine | ||
N2-Isobutyryl-7'-OH-N-DMTr-morpholino guanine is a Nucleoside Derivative - Morpholino nucleoside. | |||
TNU1328 | N2-Phenylacetyl-7’-OH-N-trityl-morpholino guanine | ||
N2-Phenylacetyl-7'-OH-N-trityl-morpholino guanine is a Nucleoside Derivative - Morpholino nucleoside; Protected nucleoside w/ NH2/OH open. | |||
TNU0385 | 1-Amino-8-benzyloxy-9-(b-D-xylofuranosyl)guanine | ||
1-Amino-8-benzyloxy-9-(b-D-xylofuranosyl)guanine is a Nucleoside Derivative - Xylo-nucleoside; 8-Modified purine nucleoside; Amino nucleoside. | |||
TNU1221 | N2-Isobutyryl-O6-cyanoethyl-7’-OH-N-trityl-morpholino guanine | ||
N2-Isobutyryl-O6-cyanoethyl-7'-OH-N-trityl-morpholino guanine is a Nucleoside Derivative - Morpholino nucleoside; Protected nucleoside w/ NH2/OH open. | |||
TNU0388 | 7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl) guanine | ||
Nucleoside Derivatives - Xylo-nucleosides; 8-Modified purine nucleosides; N-Methylated alkylated nucleosides | |||
TNU0386 | 1-Amino-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl) guanine | ||
1-Amino-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl) guanine is a Nucleoside Derivative - Xylo-nucleoside; 8-Modified purine nucleoside; Amino nucleoside. | |||
TNU0394 | 7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(b-D-ribofuranosyl)guanine | ||
7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(b-D-ribofuranosyl)guanine is a useful organic compound for research related to life sciences and the catalog number is TNU0394. | |||
TNU0383 | 7-Allyl-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl) guanine | ||
Nucleoside Derivatives - Xylo nucleosides, 8-Modified purine nucleosides; N-Methylated alkylated nucleosides | |||
TNU0440 | 7-Propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine | ||
7-Propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine is a Nucleoside Derivative - Xylo-nucleoside, N-Methylated alkylated nucleoside; 8-Modified purine nucleoside. | |||
TNU0437 | 7-Ethyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine | ||
7-Ethyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine is a Nucleoside Derivative - Xylo-nucleoside, N-Methylated alkylated nucleoside; 8-Modified purine nucleoside. | |||
TNU0438 | 7-n-Propyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine | ||
7-n-Propyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine is a Nucleoside Derivative - Xylo-nucleoside, N-Methylated alkylated nucleoside; 8-Modified purine nucleoside. | |||
TNU0387 | 1-Amino-7-cyclopropylmethyl-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl)guanine | ||
Nucleoside Derivatives - Xylo-nucleosides; 8-Modified purine nucleosides; Amino nucleosides; N-Methylated alkylated nucleosides | |||
TNU0439 | 7-n-Butyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine | ||
7-n-Butyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine is a Nucleoside Derivative - Xylo-nucleoside, N-Methylated alkylated nucleoside; 8-Modified purine nucleoside. | |||
T75052 | 7-Cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-ribofuranosyl)guanine | ||
7-Cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-ribofuranosyl)guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms... | |||
TNU0441 | 7-(Butyn-2-yl)-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine | ||
7-(Butyn-2-yl)-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)guanine is a Nucleoside Derivative - Xylo-nucleoside, N-Methylated alkylated nucleoside; 8-Modified purine nucleoside. | |||
T7539 | O6-Benzylguanine | Apoptosis , DNA Alkylation , DNA/RNA Synthesis | |
O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator. | |||
TNU1604 | 2’-O-(2-Cyanoethoxy) (diisopropylamino)phosphino-3’-O-(4,4’-dimethoxy triphenyl)methyl-N2-isobutyryl-(R)-9-(2,3-dihydroxypropyl)-guanine | ||
2'-O-(2-Cyanoethoxy) (diisopropylamino)phosphino-3'-O-(4,4'-dimethoxy triphenyl)methyl-N2-isobutyryl-(R)-9-(2,3-dihydroxypropyl)-guanine is a Nucleoside Phosphoramidite. | |||
T1646 | Famciclovir | BRL 42810 | DNA/RNA Synthesis , HSV |
Famciclovir (BRL 42810) is a Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor. The mechanism of action of famciclovir is as a DNA Polymerase Inhibitor, and DNA Polymerase Inhibitor. | |||
TNU1309 | TLR7 agonist 10 | ||
TLR7 agonist 10 is a Nucleoside Derivative - Xylo-nucleoside, N-Methylated alkylated nucleoside; 8-Modified purine nucleoside. | |||
T3089 | 6-Thioguanine | 6-TG,2-Amino-6-purinethiol,2-Amino-6-mercaptopurine,Thioguanine | Apoptosis , DNA Methyltransferase , SARS-CoV , Endogenous Metabolite , DUB , Autophagy |
6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia. | |||
T36411 | 9-Ethylguanine | Others | |
9-Ethylguanine is a model nucleobase that is used to study DNA interactions with organometallic complexes, especially those designed to target tumors. | |||
T36697 | 8-Nitroguanine | ||
8-Nitroguanine is a product of DNA nitration damage caused by reactive nitrogen species and may be a potential biomarker for the progression of malignant fibrous histiocytoma. | |||
TNU1450 | N2-iso-Butyroyl-7'-O-DMT-morpholinoguanine | ||
Nucleoside Derivatives - Morpholino nucleosides | |||
T40911 | 9-Carboxymethoxymethylguanine | ||
9-Carboxymethoxymethylguanine is the primary metabolite derived from Aciclovir, a guanosine analogue with potent antiviral properties. Aciclovir, also known as Acyclovir, acts as an orally active antiviral agent. | |||
T19148 | 5-Aza-7-deazaguanine | Others | |
5-Aza-7-deazaguanine is a substrate for E. coli purine nucleoside phosphorylase (wild-type/Ser90Ala mutant) in the synthesis of base-modified nucleosides. | |||
TNU1439 | (S)-9-[3-(4,4’-Dime thoxytrityloxy)-2-hydroxypropyl]-N2-isobutyrylguanine | ||
(S)-9-[3-(4,4'-Dime thoxytrityloxy)-2-hydroxypropyl]-N2-isobutyrylguanine is a Nucleoside Derivative - Acyclic nucleoside. | |||
T78379 | 9-Deazaguanine | Others | |
9-Deazaguanine is a nucleoside analog that exhibits potent inhibitory activity against purine nucleoside phosphorylase (PNP) [1]. | |||
T31406 | Dezaguanine | Dezaguanina,NSC 261726,CI-908,CI 908 | |
Dezaguanine is a novel antipurine antimetabolite with significant activity against transplantable rodent solid tumors, particularly breast adenocarcinoma. | |||
TNU0023 | 6-Chloroguanineriboside | ||
6-Chloroguanineriboside is a Halo nucleoside. | |||
T20102 | 8-Azahypoxanthine | NSC 22709,NSC-22709,NSC22709 | Nucleoside Antimetabolite/Analog |
8-Azahypoxanthine (NSC-22709) inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase and has antimalarial properties. | |||
T9517 | Arprinocide | Others | |
Arprinocid is an inhibitor of hypoxanthine-guanine transport | |||
T67813 | Tivicilovir | AM188 | HBV , Antifection |
Tivicilovir (AM188) is a hepatitis B virus inhibitor. tiviclovir is a guanine-related acyclic 2'-deoxyguanine analogue with anti-herpesvirus activity. | |||
T0189 | Pemetrexed | Pemetrexed acid,LY231514,LY-231514 Disodium Hydrate | DHFR , DNA/RNA Synthesis , Antifolate , Autophagy |
Pemetrexed (LY-231514 Disodium Hydrate), a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate synthase (TS). | |||
T16886 | Sinefungin | Adenosyl-Ornithine,A-9145,Antibiotic 32232RP | Others , Histone Methyltransferase , Antibiotic , Antifungal |
Sinefungin (Adenosyl-Ornithine) is an effective inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication. Sinefungin is a SET7/9 inhibitor and ameliorates r... | |||
T9985 | Methyl methanesulfonate | DNA Alkylation | |
Methyl methanesulfonate is a DNA alkylator that modifies adenine (3-methyladenine) and guanine (7-methyladenine) respectively, resulting in base mismatch and replication disorders. | |||
T2495 | Lomeguatrib | PaTrin-2 | DNA Methyltransferase , DNA Alkylation |
Lomeguatrib (PaTrin-2), a modified guanine base, inhibits the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) . | |||
TP2131L | Rac1 Inhibitor W56 acetate(1095179-01-3 free base) | Rho | |
Rac1 Inhibitor W56 acetate(1095179-01-3 free base) is a peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1. Rac1 Inhibitor W56 acetate(1095179-01-3 free ... | |||
T8930 | CID44216842 | KUC103479N-02 | CDK , Ras |
CID44216842 (KUC103479N-02) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT... | |||
T8527 | CPYPP | Others | |
CPYPP is an inhibitor of DOCK2-Rac1 interaction. CPYPP binds to DOCK2 DHR-2 domain and inhibits the guanine nucleotide exchange factor (GEF) activity of DOCK2DHR-2 for Rac1 in a dose-dependent manner(IC50 : 22.8 µM). CPY... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T2A2537 | Guanine | Pearl essence,Mearlmaid,2-Aminohypoxanthine | Others , DNA/RNA Synthesis , Endogenous Metabolite |
Guanine (2-Aminohypoxanthine) is a purine base that is a constituent of nucleotides occurring in nucleic acids. | |||
T22218 | 2'-Deoxyguanosine | Deoxyguanosine,Guanine deoxyriboside | Endogenous Metabolite |
2'-Deoxyguanosine (Guanine deoxyriboside) is a purine nucleoside that is recognized by members of the 2'-dG-II family.2'-Deoxyguanosine has been associated with aging, mutation, and carcinogenesis, and is oxidized by mol... | |||
T1709 | 2'-Deoxyinosine | Guanine deoxyriboside,Deoxyinosine | Others , Endogenous Metabolite |
2'-Deoxyinosine (Guanine deoxyriboside) inhibits the growth of human colon-carcinoma cell lines and is associated with purine nucleoside phosphorylase (PNP) deficiency. | |||
T4715 | 2'-Deoxyguanosine monohydrate | Guanine-2'-deoxyriboside | Others , Endogenous Metabolite |
2'-Deoxyguanosine monohydrate (Guanine-2'-deoxyriboside) is a nucleoside consisting of the base guanine and the sugar deoxyribose. It is like guanosine, but with one oxygen atom removed. It is a nucleoside component of D... | |||
T19382 | Isoguanine | Nucleoside Antimetabolite/Analog | |
Isoguanine is a purine base that is an isomer of guanine. A building block in organic synthesis. | |||
T13791 | N2-methylguanine | DNA/RNA Synthesis , Endogenous Metabolite , Antibacterial | |
N2-methylguanine (N2-methylguanine) is an endogenous methylated nucleoside found in human fluids and a modified nucleoside. | |||
TN7185 | 7-Cyano-7-deazaguanine | 7-CN-7-deazaG | Others |
7-Cyano-7-deazaguanine (7-CN-7-deazaG) is a marine derived natural products found in Streptomyces qinglanensis. | |||
T2218 | 8-Azaguanine | Azaguanine-8,SK 1150,NSC-749,SF-337 | Nucleoside Antimetabolite/Analog , Others , Endogenous Metabolite |
8-Azaguanine (SK 1150) is a purine analogue with potential antineoplastic activity. | |||
T19165 | 8-Hydroxyguanine | 8 Hydroxyguanine,7,8-dihydro-8-oxoguanine,2-Amino-6,8-dihydroxypurine | Endogenous Metabolite |
8-Hydroxyguanine (8 Hydroxyguanine) is the major premutagenic damage produced by reactive oxygen species. It causes G-T and A-C substitutions.8-Hydroxyguanine is a biomarker for RNA oxidation and oxidative DNA damage.8-H... | |||
T10194 | 7-Methylguanine | Others | |
7-Methylguanine is a metabolite of DNA methylation. It can be generated by methylating agents and used as a probe of DNA–protein interactions and a key component of the DNA sequencing method. | |||
TJS0405 | Lucidin | NSC 30546,Henine | Others |
1. Lucidin (NSC-30546) and its derivatives are genotoxic, it is mutagenic at the hypoxanthine-guanine phosphoribosyl transferase gene locus. | |||
T0665 | Xanthine | 2,6-Dihydroxypurine,Isoxanthine | Endogenous Metabolite , Adenosine Receptor |
Xanthine (Isoxanthine) is a product on the pathway of purine degradation. Xanthine is subsequently converted to uric acid by the action of the Xanthine oxidase enzyme. Xanthine is found in most body tissues and fluids in... | |||
T6523 | Guanosine | DL-Guanosine,Vernine,Guanozin | Endogenous Metabolite , HSV |
Guanosine (DL-Guanosine) is a purine nucleoside formed from a beta-N9-glycosidic bond between guanine and a ribose ring and is essential for metabolism. | |||
T5084 | Xanthosine dihydrate | Others , Endogenous Metabolite | |
Xanthosine is produced by guanine-free mutants of bacteria e.g. Bacillus subtilis, Aerobacter aerogenes. Xanthosine monophosphate is an intermediate in purine metabolism, formed from IMP, and forming GMP. | |||
T4746 | Purine | 7H-Imidazo(4,5-d)pyrimidine | Others , Endogenous Metabolite |
Purine (7H-Imidazo(4,5-d)pyrimidine) is a heterocyclic aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring. Two of the bases in nucleic acids, adenine and guanine, are purines. Purines f... | |||
T4839 | Ac-Ala-OH | N-Acetylalanine,N-Acetyl-L-alanine | Others , Endogenous Metabolite |
Ac-Ala-OH (N-Acetyl-L-alanine) is a substrate for Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Myelin basic protein, GTP-binding nuclear protein Ran, Tropomyosin alpha 4 chain, HIV-1 Rev binding pro... | |||
T38673 | Sibiromycin | ||
Sibiromycin, a glycosylated pyrrolobenzodiazepines (PBDs) compound, is a naturally occurring and potent antitumor antibiotic. It exerts its activity by covalently binding to DNA in the minor groove at the NH2 of guanine. |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPJ-01429 | SARS-CoV-2 Guanine-N7 methyltransferase Protein (His) | SARS-CoV-2 | E. coli |
The nonstructural protein (nsp) 14 of SARS-CoV 2 was identified as a cap (guanine-N7)-methyltransferase (N7-MTase). Nsp14 of coronaviruses two different activities: an exoribonuclease activity acting on both ssRNA and ds... | |||
TMPJ-00725 | HGPRT Protein, Human, Recombinant (His) | Human | E. coli |
Hypoxanthine-Guanine Phosphoribosyltransferase (HGPRT) has an important role in the generation of purine nucleotides through the purine salvage pathway. HPRT1 functions to salvage purines from degraded DNA to renewed pur... | |||
TMPH-00313 | TRNA (guanine-N(7)-)-methyltransferase Protein, Brugia malayi, Recombinant (His) | Brugia malayi | E. coli |
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. tRNA (guanine-N(7)-)-methyltransferase Protein, Brugia malayi, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. ... | |||
TMPK-01308 | TAG-72 Protein, Canine, Recombinant (His) | Canine | E. coli |
The guanine-N7 methyltransferase domain of vaccinia virus mRNA capping enzyme is a heterodimer composed of a catalytic subunit and a stimulatory subunit. Cap (guanine-N7) methylation is an essential step in eukaryal mRNA... | |||
TMPY-02805 | GNGT1 Protein, Human, Recombinant (His) | Human | E. coli |
GNGT1 is a subunit of transducin. Heterotrimeric G proteins consist of alpha, beta, and gamma subunits. They are membrane-bound GTPases that are linked to 7-TM receptors. They function as signal transducers for the 7-tra... | |||
TMPY-02802 | GNG13 Protein, Human, Recombinant (His) | Human | E. coli |
GNG13 is a subunit of heterotrimeric G proteins which consist of alpha, beta, and gamma subunits. Heterotrimeric G proteins are membrane-bound GTPases that are linked to 7-TM receptors. They function as signal transducer... | |||
TMPH-02041 | ARHGEF12 Protein, Human, Recombinant (His) | Human | E. coli |
ARHGEF12 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-02695 | GNAO1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Stimulated by RGS14. The G(o) protein function is not clear. | |||
TMPH-01423 | GNAZ Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. GNAZ Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression syst... | |||
TMPH-02694 | GNG12 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GD... | |||
TMPH-02693 | GNAI2 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhi... | |||
TMPH-02696 | GNAQ Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent a... | |||
TMPH-01663 | GRM5 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Sign... | |||
TMPH-02313 | RPGR Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. Plays an important role in photoreceptor integ... | |||
TMPH-00270 | GNAT2 Protein, Bovine, Recombinant (His) | Bovine | E. coli |
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that perfor... | |||
TMPH-02246 | TGS1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and... | |||
TMPH-00862 | HTR1F Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guan... | |||
TMPJ-00872 | MGMT Protein, Human, Recombinant (His) | Human | E. coli |
MGMT belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. MGMT involved in the cellular defense against the biological effects of O6-methylguanine in DNA. Repairs al... | |||
TMPH-01209 | DENND1A Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulat... | |||
TMPH-02622 | DOCK8 Protein, Mouse, Recombinant (E. coli, His) | Mouse | E. coli |
Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally a... | |||
TMPH-01422 | GNAS Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting... | |||
TMPH-01207 | DOCK8 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally a... | |||
TMPH-02623 | DOCK8 Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally a... | |||
TMPH-02675 | GCGR Protein, Mouse, Recombinant (GST) | Mouse | E. coli |
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and g... | |||
TMPY-03796 | ARF3 Protein, Human, Recombinant (His) | Human | E. coli |
ARF3, also known as ADP-ribosylation factor 3, belongs to the RAS superfamily. Members of this family include ARF1, ARF2, ARF3, ARF4, ARF5 and ARF6. ARF3 gene is a member of the human ARF gene family. These genes encode ... | |||
TMPY-03122 | GBP2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
GBP-2 belongs to the guanylate-binding protein (GBP) family. GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). As GTPases induced by IFN-gamma (Interferon-inducible GTP... | |||
TMPH-02697 | GNA12 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF12/LARG). G... | |||
TMPY-01203 | RP2 Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
XRP2, also known as Protein XRP2 and RP2, is a member of the TBCC (tubulin cofactor C) family and contains one C-CAP/cofactor C-like domain. This protein is encoded by the RP2 gene in humans. XRP2 stimulates the GTPase a... | |||
TMPY-02977 | PDE1C Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
PDE1C belongs to the cyclic nucleotide phosphodiesterase family, PDE1 subfamily. Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3' cyclic phosphate bonds ... | |||
TMPY-01661 | METTL1 Protein, Human, Recombinant (His) | Human | E. coli |
tRNA (guanine-N(7)-)-methyltransferase, also known as Methyltransferase-like protein 1, tRNA (m7G46)-methyltransferase and METTL1, is a nucleus protein that belongs to the methyltransferase superfamily and TrmB family. M... | |||
TMPY-04443 | NEK3 Protein, Mouse, Recombinant (His & GST) | Mouse | Baculovirus Insect Cells |
NEK3 (NIMA (never in mitosis gene a)-related expressed kinase 3), contains 1 protein kinase domain and is a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. Members of the NEK family of... | |||
TMPY-02399 | TRF1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Telomeric repeat binding factor 1 (TRF1), also known as TERF1, the shelterin complex, which modulates the telomere structures. TRF1 protein structure contains a C-terminal Myb motif, a dimerization domain near its N-term... | |||
TMPY-01479 | SPG3A Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
Atlastin-1, also known as Spastic paraplegia 3 protein A, Guanine nucleotide-binding protein 3, GTP-binding protein 3, GBP3, ATL1 and SPG3A, is a multi-pass membrane protein which belongs to theGBP family and atlastin... | |||
TMPH-02521 | PYCARD Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Functions as key mediator in apoptosis and inflammation. Promotes caspase-mediated apoptosis involving predominantly caspase-8 and also caspase-9 in a probable cell type-specific manner. Involved in activation of the mit... |