ホーム 計算ツール
代理店ログイン

検索結果

Search Results for " OSC "

24

阻害剤

32

天然化合物

10

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T20174 Tetrahexyldecyl ascorbate BV-OSC,Oristar THA,Nikkol BV-OSC
Tetrahexyldecyl ascorbate is one of vitamin C.
T4039 BIBB 515 Others
BIBB 515 is a selective and potent inhibitor of OSC in vivo with an ED50 value of 0.2-0.5 and 0.36-33.3 mg/kg in rats and mice, respectively. 2, 3-Oxidosqualene cyclase (OSC) is an important enzyme in the biosynthesis of...
T9422 Fosciclopirox CPX-POM Gamma-secretase
Fosciclopirox (CPX-POM), the phosphoryloxymethyl ester of CPX (Ciclopirox Prodrug, CPX-POM), selectively delivers the active metabolite, CPX, to the entire urinary tract following parenteral administration.
T1383 Bitoscanate p-Phenylene diisothiocyanate,Biscomate,PDITC,1,4-Diisothiocyanatobenzene Parasite
Bitoscanate (PDITC) is used in the treatment of hookworms.
T0220 Foscarnet sodium Phosphonoformate Virus Protease , Reverse Transcriptase , DNA/RNA Synthesis
Foscarnet sodium (Phosphonoformate) is an antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
T36141 Boscalid Mitochondrial Metabolism
Boscalid is a broad-spectrum carboxamide fungicide that inhibits fungal respiration by binding to the ubiquinone site of mitochondrial complex II/succinate dehydrogenase.1It suppresses mycelial growth ofS. minorby 87 to ...
T31858 Foscolic acid PDLA,Phoscolic acid
Foscolic acid is a bioactive chemical.
T124103 Helioscopinolide A
Helioscopinolide A is a useful organic compound for research related to life sciences. The catalog number is T124103 and the CAS number is 84744-64-9.
T126411 Glucoscillaren A
Glucoscillaren A is a useful organic compound for research related to life sciences. The catalog number is T126411 and the CAS number is 11003-96-6.
T15339 Foscarbidopa Carbidopa 4′-monophosphate Dopamine Receptor
Foscarbidopa is a prodrug of Carbidopa. It acts as a dopamine receptor agonist.
T33352 Methylepoxyproscillaridin
Methylepoxyproscillaridin is a semisynthetic cardiac glycoside.
T124151 Myoscorpine
Myoscorpine is a useful organic compound for research related to life sciences and the catalog number is T124151.
T33690 Nitroscanate Lopatol,CGA-23654GS,CGA 23654
Nitroscanate is an anthelmintic found to be effective in certain strains of parasites in canines.
T63721 Fosclevudine alafenamide
Fosclevudine alafenamide (Compound EIDD-02173) is an antiviral agent that acts against HBV (EC50: 1.71 μM).
T25505 Homomoschatoline Liridine,O-Methyl-moschatoline
Homomoschatoline is an antibacterial isolated from Artabotrys crassifolius.
T20392 Hyoscyamine hydrobromide l-Hyoscyamine hydrobromide
Hyoscyamine hydrobromide is an agent of anticholinergic.
T75597 Loxosceles Spiniceps Venom
Loxosceles Spiniceps Venom, derived from Loxosceles Spiniceps, is a complex venom composed of proteins, glycoproteins, and low molecular mass peptides. This venom contains various protein classes such as astacin-like met...
T75595 Loxosceles Bergeri Venom
Loxosceles Bergeri venom, derived from Loxosceles Bergeri, comprises a sophisticated blend of toxins featuring proteins, glycoproteins, and low molecular mass peptides. Identified protein classes within this venom includ...
T75596 Loxosceles Pilosa Venom
Loxosceles Pilosa Venom, derived from Loxosceles Pilosa, comprises a sophisticated blend of proteins, glycoproteins, and low molecular mass peptides. This venom contains various protein classes such as astacin-like metal...
T23731 Amoscanate GO 9333,CCRIS 4111,Ciba 9333 GO,C 9333 GO,CGP 4540
Amoscanate is an antiparasitic agent. It is highly effective in animals against the four major species of schistosomes which infect humans.
T70056 Moschamine
Moschamine is an inhibitor of mitochondrial superoxide overproduction.
T33291 Meproscillarin KY-18,Rambufaside,Clift,KY 18,KY18
Meproscillarin is a glycoside with high bioavailability (about 70%) and an elimination independent of renal function.
T32531 Lactoscatone Hydroxy-4,7,7-trimethyl-4-carboxylic acid-lactone,EINECS 244-310-6
Lactoscatone is a biochemical.
T1771 Ro 48-8071 fumarate Others
Ro 48-8071 fumarate is an inhibitor of OSC(Oxidosqualene cyclase; IC50=6.5 nM) that has low-density lipoprotein (LDL) cholesterol lowering activity.

Compounds

Tetrahexyldecyl ascorbate
T20174
Synonym: BV-OSC,Oristar THA,Nikkol BV-OSC
Target:
BIBB 515
T4039
Synonym:
Target: Others
Fosciclopirox
T9422
Synonym: CPX-POM
Target: Gamma-secretase
Bitoscanate
T1383
Synonym: p-Phenylene diisothiocyanate,Biscomate,PDITC,1,4-Diisothiocyanatobenzene
Target: Parasite
Foscarnet sodium
T0220
Synonym: Phosphonoformate
Target: Virus Protease, Reverse Transcriptase, DNA/RNA Synthesis
Boscalid
T36141
Synonym:
Target: Mitochondrial Metabolism
Foscolic acid
T31858
Synonym: PDLA,Phoscolic acid
Target:
Helioscopinolide A
T124103
Synonym:
Target:
Glucoscillaren A
T126411
Synonym:
Target:
Foscarbidopa
T15339
Synonym: Carbidopa 4′-monophosphate
Target: Dopamine Receptor
Methylepoxyproscillaridin
T33352
Synonym:
Target:
Myoscorpine
T124151
Synonym:
Target:
Nitroscanate
T33690
Synonym: Lopatol,CGA-23654GS,CGA 23654
Target:
Fosclevudine alafenamide
T63721
Synonym:
Target:
Homomoschatoline
T25505
Synonym: Liridine,O-Methyl-moschatoline
Target:
Hyoscyamine hydrobromide
T20392
Synonym: l-Hyoscyamine hydrobromide
Target:
Loxosceles Spiniceps Venom
T75597
Synonym:
Target:
Loxosceles Bergeri Venom
T75595
Synonym:
Target:
Loxosceles Pilosa Venom
T75596
Synonym:
Target:
Amoscanate
T23731
Synonym: GO 9333,CCRIS 4111,Ciba 9333 GO,C 9333 GO,CGP 4540
Target:
Moschamine
T70056
Synonym:
Target:
Meproscillarin
T33291
Synonym: KY-18,Rambufaside,Clift,KY 18,KY18
Target:
Lactoscatone
T32531
Synonym: Hydroxy-4,7,7-trimethyl-4-carboxylic acid-lactone,EINECS 244-310-6
Target:
Ro 48-8071 fumarate
T1771
Synonym:
Target: Others
カタログ番号 製品名 別名 ターゲット
T6473 Dioscin CCRIS 4123,Collettiside III,Saponin Apoptosis , Autophagy
Dioscin (Collettiside III) is a saponin with antitumor activities.
T3771 Methyl protodioscin Smilax saponin B,NSC-698790 Apoptosis
Methyl protodioscin (Smilax saponin B) potentially increase HDL cholesterol while reducing LDL cholesterol and triglycerides. Methyl protodioscin has antitumor property. Methyl protodioscin induced apoptotic process in h...
T4S1619 L-Hyoscyamine sulfate Hyoscyamine sulfate hydrate,Levsin Sulfate,Hyoscyamine Sulphate AChR
L-Hyoscyamine sulfate (Levsin Sulfate) is the sulfate salt of a belladonna alkaloid derivative and the levorotatory form of racemic atropine isolated from the plants Hyoscyamus niger or Atropa belladonna, which exhibits ...
TN1803 Isoscoparin Antioxidant , TNF , NO Synthase , Fatty Acid Synthase
Isoscoparin is derived from Gentiana algida Pall with antioxidant and anti-adipogenic activities. Isoscoparin can be used in stuides about the prevention and treatment of obesity.
TN2105 Proscillaridin A Topoisomerase
Proscillaridin A is a natural product.It is a potent poison of topoisomerase I/II activity with IC50 values of 30 nM and 100 nM, respectively.
T5S0246 Pseudoprotodioscin Others , Fatty Acid Synthase
1. Pseudoprotodioscin has moderate cytotoxicity.
T0962 L-Hyoscyamine Daturine,Hyoscyamine AChR
L-Hyoscyamine (Daturine) functions as a non-selective, competitive antagonist of muscarinic receptors, thereby inhibiting the parasympathetic activities of acetylcholine on the salivary, bronchial, and sweat glands, as w...
TN1032 Geissoschizine methyl ether 5-HT Receptor
Geissoschizine methyl ether, a major indole alkaloid found in Uncaria hook, is a major active component of Yokukansan with psychotropic effects. Geissoschizine methyl ether is a potent serotonin A receptor agonist and ca...
T3897 Isoschaftoside Anti-infection , Antifungal
Isoschaftoside is used as an intercrop due to its allelopathic inhibition of parasitism by Striga hermonthica, an obligate parasitic weed that can devastate the maize crop. Isoschaftoside has anti-tumor, antioxidant, and...
T2321 Protodioscin Furostanol I Androgen Receptor , Endogenous Metabolite
Protodioscin (Furostanol I) is a major steroidal saponin in dioscoreae rhizome, with anti-hyperlipidemia, anti-cancer properties.
T3815 Isoscopoletin 7-Methoxyesculetin,6-Hydroxy-7-methoxycoumarin Others , HBV
Isoscopoletin (7-Methoxyesculetin) is a predicted metabolite generated by BioTransformer1 that is produced by the metabolism of 6, 7-dimethoxy-2h-chromen-2-one.
TN6569 Cis-Moschamine
cis-Moschamine exerts antitumour effects on HeLa, MCF7 and A431 cells.
TN6853 Isosclerone
Isosclerone is a natural product.
TN5364 Boscialin
Boscialin can inhibit signal transducer and activator of transcription 1 translocation at a concentration of 10 uM.
TN1954 Moscatin Others
Moscatin exhibits antiplatelet aggregation activity.
TN4431 Leucosceptoside A RAAS , PKC
Leucosceptoside A shows inhibitory activity against PKCalpha with the IC50 value of 19.0 microM; it also exhibits strong inhibitory capacity against α-glucosidase. Leucosceptoside A has antihypertensive effect, it shows ...
TN6567 Neoschaftoside
Neoschaftoside has antioxidant activity.
TN4517 Meloscandonine Others
Meloscandonine is a natural product for research related to life sciences. The catalog number is TN4517 and the CAS number is 28645-27-4.
T82026 Isoscutellarein 8-O-β-D-glucuronide
Isoscutellarein 8-O-β-D-glucuronide, a flavonoid antioxidant, can be isolated from the seeds of Theobroma grandiflorum [1] [2].
TN6262 Boschnaloside
Boschnaloside is a natural product for research related to life sciences. The catalog number is TN6262 and the CAS number is 72963-55-4.
TN5394 3-epi-Dihydroscandenolide 15,6-diolide,3β-Acetoxy-1,10-epoxy-4-germacrene-12,8;15,6-diolide,3β-Acetoxy-1,10-epoxy-4-germacrene-12,8
3-epi-Dihydroscandenolide is a natural product for research related to life sciences. The catalog number is TN5394 and the CAS number is 1137951-08-6.
TN2700 2,3-dihydrosciadopitysin Others
2,3-dihydrosciadopitysin is a natural product of Podocarpus, Podocarpaceae. The catalog number is TN2700 and the CAS number is 34421-19-7. 2,3-dihydrosciadopitysin can be used as a reference standard.
T72733 Geissoschizoline (+)-Geissoschizoline
Geissoschizoline ((+)-Geissoschizoline), with IC50 values of 20.40 µM for human AChE and 10.21 µM for BChE, functions as a potent inhibitor and emerges as a promising multi-target prototype for research into preventing n...
TN3434 Apohyoscine Others
Apohyoscine is a natural product of Datura, Solanaceae. The catalog number is TN3434 and the CAS number is 535-26-2. Apohyoscine can be used as a reference standard.
T83257 7(8)-Dehydroschisandrol A
7(8)-Dehydroschisandrol A (Compound 4a), a lignan extracted from Schizandra chinensis Baill, exhibits a mild inhibitory activity against stress-induced gastric ulcers [1].
T83258 7(18)-Dehydroschisandro A
7(18)-Dehydroschisandro A (Compound 2), a lignan isolated from Schizandra chinensis Baill, exhibits inhibitory effects on stress-induced gastric ulcers [1].
TN3724 Cryptomoscatone D2 p53
Cryptomoscatone D2 is a highly efficacious inhibitor of the G(2) checkpoint, and G(2) checkpoint inhibitors can force cells arrested in G(2) phase by DNA damage to enter mitosis.
TN5395 Anhydroscandenolide
Anhydroscandenolide is a natural product for research related to life sciences. The catalog number is TN5395 and the CAS number is 114742-71-1.
TN1135 Isoscabertopin Others
Isoscabertopin has anticancer activity.
T82427 Euphoscopin C
Euphoscopin C, a diterpenoid isolated from Euphorbia helioscopia, significantly enhances the cytotoxic activity of natural killer (NK) cells against H1299-luci and A549-luci cells [1].
TN1802 Isoscoparin-2′′O-glucoside Isoscoparin-2''-Beta-D-glucopyranoside Others
Isoscoparin-2''-Beta-D-glucopyranoside shows prominent free radical scavenging activity in DPPH assay.
TN5593 Euphohelioscopin A
Euphohelioscopin A, an activator of protein kinase C (PKC), it inhibits proliferation and induces differentiation of the myeloid leukemia cell lines THP-1 and HL-60. Euphohelioscopin A has anti-inflammary activity, it ex...

天然物製品

Dioscin
T6473
Synonym: CCRIS 4123,Collettiside III,Saponin
Target: Apoptosis, Autophagy
Methyl protodioscin
T3771
Synonym: Smilax saponin B,NSC-698790
Target: Apoptosis
L-Hyoscyamine sulfate
T4S1619
Synonym: Hyoscyamine sulfate hydrate,Levsin Sulfate,Hyoscyamine Sulphate
Target: AChR
Isoscoparin
TN1803
Synonym:
Target: Antioxidant, TNF, NO Synthase, Fatty Acid Synthase
Proscillaridin A
TN2105
Synonym:
Target: Topoisomerase
Pseudoprotodioscin
T5S0246
Synonym:
Target: Others, Fatty Acid Synthase
L-Hyoscyamine
T0962
Synonym: Daturine,Hyoscyamine
Target: AChR
Geissoschizine methyl ether
TN1032
Synonym:
Target: 5-HT Receptor
Isoschaftoside
T3897
Synonym:
Target: Anti-infection, Antifungal
Protodioscin
T2321
Synonym: Furostanol I
Target: Androgen Receptor, Endogenous Metabolite
Isoscopoletin
T3815
Synonym: 7-Methoxyesculetin,6-Hydroxy-7-methoxycoumarin
Target: Others, HBV
cis-Moschamine
TN6569
Synonym:
Target:
Isosclerone
TN6853
Synonym:
Target:
Boscialin
TN5364
Synonym:
Target:
Moscatin
TN1954
Synonym:
Target: Others
Leucosceptoside A
TN4431
Synonym:
Target: RAAS, PKC
Neoschaftoside
TN6567
Synonym:
Target:
Meloscandonine
TN4517
Synonym:
Target: Others
Isoscutellarein 8-O-β-D-glucuronide
T82026
Synonym:
Target:
Boschnaloside
TN6262
Synonym:
Target:
3-epi-Dihydroscandenolide
TN5394
Synonym: 15,6-diolide,3β-Acetoxy-1,10-epoxy-4-germacrene-12,8;15,6-diolide,3β-Acetoxy-1,10-epoxy-4-germacrene-12,8
Target:
2,3-dihydrosciadopitysin
TN2700
Synonym:
Target: Others
Geissoschizoline
T72733
Synonym: (+)-Geissoschizoline
Target:
Apohyoscine
TN3434
Synonym:
Target: Others
7(8)-Dehydroschisandrol A
T83257
Synonym:
Target:
7(18)-Dehydroschisandro A
T83258
Synonym:
Target:
Cryptomoscatone D2
TN3724
Synonym:
Target: p53
Anhydroscandenolide
TN5395
Synonym:
Target:
Isoscabertopin
TN1135
Synonym:
Target: Others
Euphoscopin C
T82427
Synonym:
Target:
Isoscoparin-2′′O-glucoside
TN1802
Synonym: Isoscoparin-2''-Beta-D-glucopyranoside
Target: Others
Euphohelioscopin A
TN5593
Synonym:
Target:

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPK-01117 OSCAR Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Osteoclast-associated receptor (OSCAR) is a co-stimulatory receptor in osteoclastogenesis. Synovial tissues from active rheumatoid arthritis (RA) patients express higher levels of OSCAR compared with osteoarthritic and n...
TMPK-01092 OSCAR Protein, Human, Recombinant (hFc) Human HEK293 Cells
Osteoclast-associated receptor (OSCAR) is a co-stimulatory receptor in osteoclastogenesis. Synovial tissues from active rheumatoid arthritis (RA) patients express higher levels of OSCAR compared with osteoarthritic and n...
TMPJ-00871 BAR Protein, S. hygroscopicus, Recombinant Streptomyces hygroscopicus E. coli
Phosphinothricin N-acetyltransferase (PAT) is an enzyme that acetylates the free NH2 group of L-phosphinothricin (L-PPT) in the presence of acetyl-CoA as a co-substrate. It is highly specific for L-PPT and does not acety...
TMPH-00818 Delta-theraphotoxin-Hm1a Protein, Heteroscodra maculata, Recombinant (His & Myc & SUMO) Heteroscodra maculata E. coli
Delta-theraphotoxin-Hm1a Protein, Heteroscodra maculata, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO and C-Myc tag. The predicted molecular weight is 21.5 kDa and the access...
TMPH-03604 Phosphinothricin N-acetyltransferase Protein, Streptomyces hygroscopicus, Recombinant (His) Streptomyces hygroscopicus E. coli
Inactivates phosphinothricin (PPT) by transfer of an acetyl group from acetyl CoA. Can also acetylate demethylphosphinothricin but not PTT or glutamate. This enzyme is an effector of phosphinothricin tripeptide (PTT or b...
TMPH-02034 Retinoschisin Protein, Human, Recombinant (His) Human E. coli
Retinoschisin Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-00346 Limulus clotting factor C Protein, Carcinoscorpius rotundicauda, Recombinant (His) Carcinoscorpius rotundicauda E. coli
This enzyme is closely associated with an endotoxin-sensitive hemolymph coagulation system which may play important roles in both hemostasis and host defense mechanisms. Its active form catalyzes the activation of factor...
TMPY-04306 Influenza A H3N2 (A/Moscow/10/1999) Hemagglutinin/HA1 Protein (His) H3N2 HEK293 Cells
Influenza A H3N2 (A/Moscow/10/1999) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is Q1NZ37.
TMPY-00024 Influenza A H3N2 (A/Moscow/10/1999) Hemagglutinin/HA Protein (His) H3N2 Baculovirus Insect Cells
Influenza A H3N2 (A/Moscow/10/1999) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.3 kDa and the accession number is Q1NZ37.
TMPY-05325 Exosome Component 9/EXOSC9 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Exosome Component 9/EXOSC9 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 51.3 kDa and the accession number is Q06265-1.