| T3981 |
Acacetin
|
4'-Methoxyapigenin,5,7-Dihydroxy-4'-methoxyflavone,Linarigenin |
Apoptosis
,
IAP
,
COX
,
Autophagy
|
|
Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an O-methylated flavone found in various plants, shows antinociceptive, anti-inflammatory, and antioxidant activity in various research models. |
| T7060 |
Amantadine
|
1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine |
Others
|
|
Amantadine (1-Aminoadamantane) is an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake. |
| TN1600 |
Eclalbasaponin I
|
|
Others
|
|
Eclalbasaponin I has anti-oxidative, and antitumor activities, it reduces oxidative stress-induced neural cell death by autophagy activation, it can dose-dependently inhibit the proliferation of hepatoma cell smmc-7721 w... |
| T5826 |
Eupalinolide A
|
|
HSP
|
|
Eupalinolide B is a natural product ,and demonstrates potent cytotoxicity against A-549, BGC-823, SMMC-7721, and HL-60 tumour cell lines. |
| T5352 |
GLYCODEOXYCHOLIC ACID
|
|
Others
,
Endogenous Metabolite
|
|
Glycodeoxycholic Acid is a bile acid that induces severe pancreatitis in rats. It can induce the apoptosis of SMMC-7721 cells. |
| T5S0761 |
Nitidine chloride
|
|
Apoptosis
,
ERK
,
FAK
,
p38 MAPK
,
NF-κB
,
Topoisomerase
,
STAT
,
Parasite
|
|
1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and id... |
| TN5676 |
Musellarin B
|
|
|
|
Musellarin B is cytotoxic toward several of the human tumor cell lines (HL-60, SMMC-7721, A-549, MCF-7, and SW480). |
| TN3250 |
7-Prenyljacareubin
|
|
Others
|
|
7-Prenyljacareubin shows moderate cytotoxic activity against HL-60, SMMC-7721, A549, MCF-7, and SW480 cell lines. |
| TN1200 |
19-Oxocinobufotalin
|
|
Others
|
|
19-Oxocinobufotalin 3-adipoylarginine ester shows significant inhibition effect against human hepatocellular carcinoma cell line SMMC-7721 in vitro. |
| TN5574 |
Heudelotinone
|
|
|
|
Heudelotinone shows cytotoxicity against three cancer cell lines A549, Hela, and SMMC-7721( IC50 values of 16.04, 10.67 and 21.68 uM , respectively). |
| TN3740 |
Cyclocommunol
|
|
PAFR
|
|
Cyclocommunol exhibits cytotoxicity against hepatocellular carcinoma (SMMC-7721) and gastric carcinoma (BGC-823 and SGC-7901) cell lines. It also shows strong inhibition of arachidonic acid (AA)- and collagen-induced pla... |
| TN3371 |
Albatrelin G
|
|
Others
|
|
Albatrelin G shows weak cytotoxic activity to cell lines HL-60, SMMC-7721, A-549, and MCF-7, in vitro. |
| TN3825 |
Demethylmurrayanine
|
|
Others
|
|
O-Demethylmurrayanine and clausine D exhibit strong cytotoxicity against MCF-7 and SMMC-7721 with IC50 values in the range 2.63-7.59 ug/ml. |
| TN1865 |
Licoricesaponin A3
|
|
Others
|
|
Licoricesaponin A3 shows the cytotoxic activity against the human cancer cell lines MGC-803, SW620, and SMMC-7721 with IC50 > 100 μMol/L. |
| TN5204 |
Uralsaponin C
|
|
Others
|
|
Uralsaponin C shows the cytotoxic activity against the human cancer cell lines MGC-803, SW620, and SMMC-7721 with IC50 > 100 μmol/L. |
| TN2052 |
Periplocoside M
|
|
Others
|
|
Periplocoside M possesses observably antitumor activity against SMMC-7721( IC 50=12.9 ng/L),Hela( IC 50=8.63 ng/L) and MCF-7( IC 50=18.5 ng/L) cancer cell lines. |
| TN1498 |
Cimigenol
|
|
Others
|
|
Cimigenol is a potential antitumor compound, combination of it with an autophagy inhibitor may be a valuable strategy for the chemoprevention or treatment of colon cancer. It exerted potent cytotoxic activity against SMM... |
| T83461 |
11-Oxomogroside IV A
|
|
|
|
11-Oxomogroside IV A (compound 12), a cucurbitane triterpene glycoside extracted from the unripe fruits of Luo Han Guo, exhibits anti-tumor properties and demonstrates cytotoxicity towards SMMC-7721 tumor cells, with an ... |
| TN3925 |
Eichlerianic acid
|
|
HSV
|
|
Eichlerianic acid is a trypanocidal compound with an IC50 value of 10 mg/mL. Eichlerianic acid may have antiviral activity against Herpes simplex virus types I and II in vitro. Eichlerianic acid shows weak cytotoxicity (... |
| TN3616 |
Cedrelone
|
|
Apoptosis
,
MMP
,
Antifection
|
|
Cedrelone is a citrulline analog and a phenazine biosynthesis-like domain protein (PBLD) activator.Cedrelone induces apoptosis in cancer cells.Cedrelone is a very potent inducer of apoptosis, causing cell cycle arrest.Ce... |
| TN4624 |
Nantenine
|
|
Others
|
|
Nantenine is an acetylcholinesterase inhibitor, it functions as an effective antagonist against a wide range of MDMA-induced effects in mice. Nantenine has anticonvulsant effect, which seems attributable to its stimulati... |
