|
T5051 |
Isopropamide Iodide
|
|
AChR
|
|
Isopropamide iodide is a long-acting anticholinergic drug. It is used in the treatment of peptic ulcers and other gastrointestinal disorders. It also acts as a muscarinic receptor antagonist which can be applied to the t... |
|
T4981 |
Anisotropine Methylbromide
|
|
Prostaglandin Receptor
,
AChR
|
|
Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion. |
|
T1460 |
Dicyclomine hydrochloride
|
|
AChR
|
|
Dicyclomine hydrochloride is a muscarinic antagonist used as an antispasmodic and in urinary incontinence. |
|
T9353 |
OXOMEMAZINE
|
|
AChR
,
Histamine Receptor
|
|
Oxomemazine is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic activity. Oxomemazine is a selective antagonist of mycotoxins M1 receptors, showing high (Ki=84 nM, M1 receptors) and low ... |
|
T22380 |
Nor-benzetimide
|
|
Others
,
AChR
|
|
Norbenzetimide, an organic compound, is prepared from benzetimide by catalytic transfer hydrogenolysis. |
|
T5023 |
Propiverine hydrochloride
|
|
Others
,
Calcium Channel
,
AChR
|
|
Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB). |
|
T0023 |
Valethamate bromide
|
Ediposin,Epidozin,Epidosin,Resitan |
Others
|
|
Valethamate bromide (Resitan) is an anticholinergic agent that has antispasmodic effects and inhibits glandular secretion. |
|
T1472 |
Trospium chloride
|
Spasmex,Sanctura |
AChR
|
|
Trospium chloride (Spasmex) is an antispasmodic and anticholinergic agent used to treat urinary incontinence and overactive bladder syndrome. Trospium chloride has not been implicated in causing liver enzyme elevations o... |
|
T16472 |
Pericyazine
|
Propericiazine,RP 8909 |
Dopamine Receptor
|
|
Pericyazine (Propericiazine) is a selective D2-dopamine receptor antagonist. Pericyazine is a first-generation antipsychotic drug that is used as an adjunct to the short-term management of severe anxiety states and psych... |
|
T28827 |
Sofpironium bromide
|
BBI4000,BBI 4000,BBI-4000 |
Others
,
AChR
|
|
Sofpironium bromide (BBI4000) belongs to a class of drugs called anticholinergics, which exert their effect by blocking the action of acetylcholine. |
|
T1072 |
Loxeen
|
Pridinol methanesulfonate |
AChR
|
|
Loxeen (Pridinol methanesulfonate) is used as an anticholinergic and as an antiparkinsonian agent. |
|
T4979 |
Procyclidine hydrochloride
|
(±)-Procyclidine hydrochlorid |
NMDAR
,
iGluR
|
|
Procyclidine hydrochloride ((±)-Procyclidine hydrochlorid) is a potent anticholinergic agent and also have NMDA antagonist properties. |
|
T1336 |
Benztropine mesylate
|
Benzotropine mesylate,Benzatropine mesylate,Benztropine methanesulfonate |
Dopamine Receptor
,
AChR
,
Histamine Receptor
|
|
Benztropine mesylate (Benztropine methanesulfonate) is a centrally active muscarinic antagonist that has been used in the symptomatic treatment of PARKINSON DISEASE. Benztropine also inhibits the uptake of dopamine. |
|
T1567 |
Olanzapine
|
LY170053 |
Dopamine Receptor
,
5-HT Receptor
,
Adrenergic Receptor
,
AChR
|
|
Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness. |
|
T0205 |
Brompheniramine maleate
|
Dimotane,Rolabromophen,Brompheniramine hydrogen maleate,Dimetane |
5-HT Receptor
,
Histamine Receptor
|
|
Brompheniramine maleate (Dimotane) is an antagonist against histamine H1 receptors. |
|
T0218 |
Biperiden
|
Bipariden,Akineton,KL 373,Biperidine |
AChR
|
|
Biperiden (Bipariden) is a muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. ... |
|
T13118 |
Temiverine hydrochloride
|
|
Calcium Channel
|
|
Temiverine hydrochloride is a potential calcium channel antagonist with anticholinergic effects that inhibits some of the functions of atropine. |
|
T10732 |
Tematropium
|
CDDD3602,Tematropium metilsulfate,HGP6 |
AChR
|
|
Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies. |
|
T21014 |
Thonzylamine hydrochloride
|
Resistab,Thonzylamine HCl,Novohetramin,Neohetramine hydrochloride,Anahist |
AChR
,
Histamine Receptor
|
|
Thonzylamine hydrochloride (Resistab) is an anticholinergic and antihistamine used as an antipruritic. |
|
T7477 |
Antazoline
|
|
Others
|
|
Antazoline has antihistamine and anticholinergic effects.It used to treat a variety of arrhythmias. |
|
T7564 |
Chlorphenoxamine
|
Contristamine |
Histamine Receptor
|
|
Chlorphenoxamine (Contristamine) is an antihistamine and anticholinergic used as an antipruritic and antiparkinsonian agent. |
|
T0147 |
Clemastine fumarate
|
HS-592 (fumarate),Meclastine fumarate,Meclastine (fumarate) |
Autophagy
,
Histamine Receptor
|
|
Clemastine fumarate (Meclastine (fumarate)) is a synthetic ethanolamine with anticholinergic, sedative, and histamine H1 antagonistic properties. |
|
T68082 |
Glycopyrronium tosylate
|
|
|
|
Glycopyrronium tosylate an anticholinergic compound used in the treatment of axillary hyperhidrosis for the study of a variety of cryptobacterial tumors. |
|
T35033 |
Vamicamide
|
FK 176,FK-176,FK176 |
AChE
|
|
Vamicamide (FK 176) is a novel anticholinergic compound. Vamicamide increases spontaneous locomotor activity in mice at 32 mg/kg (p.o.) or higher and inhibits cataleptic convulsions in mice at 100 mg/kg. |
|
T31488 |
Dimethindene
|
Dimetindeno,Z 2001,Dimetindene,Z-2001,Z2001 |
Potassium Channel
,
Endogenous Metabolite
,
AChR
,
Histamine Receptor
|
|
Dimethindene (Dimetindeno) is a selective antagonist of H1 receptor and blocks K+ current. Dimethindene exhibits antihistamine and anticholinergic effects. |
|
T1049L |
Oxybutynin
|
Oxytrol,Ditropan,Oxibutyninum |
Potassium Channel
,
AChR
|
|
Oxybutynin (Ditropan) is a synthetic anticholinergic agent that is used for treatment of urinary incontinence and overactive bladder syndrome. |
|
T33846 |
Oxyphenonium bromide
|
Spasmophen,Oxifenon,Oxyfenon,Atrenyl,Oxyphenon |
Others
|
|
Oxyphenonium bromide (Oxyfenon) shows anticholinergic activity and can be used for research on the treatment of gastric and duodenal ulcers and for the relief of visceral spasms. |
|
T0594 |
Diphenmanil methylsulfate
|
Diphemanil mesylate,Diphemanil Methylsulfate |
AChR
|
|
Diphenmanil methylsulfate (Diphemanil mesylate), a quaternary ammonium anticholinergic, binds muscarinic acetylcholine receptors and thus decreases secretory excretion of stomach acids, sweat, and saliva. |
|
T6547 |
Ipratropium Bromide
|
Sch 1000,Itrop,Atrovent |
AChR
|
|
Ipratropium Bromide (Sch 1000) is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis and emphysema. |
|
T1049 |
Oxybutynin chloride
|
Oxybutynin hydrochloride,Oxybutynin HCl |
Potassium Channel
,
AChR
|
|
Oxybutynin chloride (Oxybutynin HCl) is an anticholinergic medication used to relieve urinary and bladder difficulties. It competitively antagonizes the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor. |
|
T17210L1 |
(3R,6R)-Vaborbactam
|
(3R,6R)-RPX7009,(3R,6R)-Vaborbactam (Iso-1360457-46-0) |
Antibacterial
|
|
(3R,6R)-Vaborbactam ((3R,6R)-Vaborbactam (Iso-1360457-46-0)) is a cyclic boronic acid pharmacophore β-lactamase inhibitor with potential antimicrobial activity. (S)-Vamicamide ((S)-Vamicamide (Iso-132373-81-0)) is a nove... |
|
T61233 |
Penehyclidine hydrochloride
|
Penequinine hydrochloride |
NF-κB
,
AChR
|
|
Penehyclidine hydrochloride (Penequinine hydrochloride) is an M1 and M3 antagonist and activates NF-κB in lung tissue. Penehyclidine hydrochloride inhibits the release of inflammatory factors and shows anticholinergic pr... |
|
T21419 |
Diphenhydramine
|
Debendrin,PM 255,PM255,Dabylen,Syntedril,PM-255 |
Histamine Receptor
|
|
Diphenhydramine (Syntedril), a first-generation antihistamine possessing antiemetic, antitussive, anticholinergic, and sedative properties, is mainly used in the treatment of allergies. Diphenhydramine is also used in th... |
|
T0776 |
Phenothiazine
|
ENT 38 |
Dopamine Receptor
,
Antibacterial
,
Antibiotic
,
Antifungal
|
|
Phenothiazine (ENT 38) is a class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Phenothiazines antagonize the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ)... |
|
T0785 |
Dexchlorpheniramine Maleate
|
S-(+)-Chlorpheniramine maleate salt |
Dopamine Receptor
,
5-HT Receptor
,
Norepinephrine
,
Histamine Receptor
|
|
Dexchlorpheniramine Maleate (S-(+)-Chlorpheniramine maleate salt) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria. It is the pharmacologically active d... |
|
T35033L |
(S)-Vamicamide
|
(S)-Vamicamide (Iso-132373-81-0) |
AChE
|
|
(S)-Vamicamide is a novel anticholinergic compound.Vamicamide increases spontaneous locomotor activity in mice at 32 mg/kg or higher (p.o.) and inhibits tonic convulsions in mice at 100 mg/kg.CAS 번호13483-86-1 |
|
T77678 |
TZ3O
|
|
AChR
|
|
TZ3O is an anticholinergic compound with neuroprotective activity.TZ3O ameliorates memory impairment and cognitive decay in Scopolamine-induced Alzheimer's type model in rats, and can be used in the study of Alzheimer's ... |
|
T4563 |
Thonzylamine
|
neohetramine |
Histamine Receptor
|
|
Thonzylamine (neohetramine) is an antihistamine and anticholinergic drug. It is available as combination products with Clofedanol or Phenylephrine for temporary relief of symptoms of common cold, hay fever (allergic rhin... |
|
T2555 |
Aclidinium bromide
|
LAS 34273,LAS-W 330 |
AChR
|
|
Aclidinium bromide (LAS-W 330) is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis or emphysema. Aclidinium has not been implicated in causing li... |
|
T15044 |
D609
|
|
Apoptosis
,
Antioxidant
|
|
D609 (Tricyclodecan-9-yl-Xanthogenate) has a wide range of biological activities including antioxidant, antiapoptotic, anticholinergic, antitumor, anti-inflammatory, antiviral, antiproliferative, and neuroprotective acti... |
|
T0059 |
Diphenylpyraline hydrochloride
|
4-Diphenylmethoxy-1-methylpiperidine hydrochloride |
Histamine Receptor
|
|
Diphenylpyraline hydrochloride (4-Diphenylmethoxy-1-methylpiperidine hydrochloride) is used in the treatment of Parkinsonism.It is a first-generation antihistamine with anticholinergic effects, functions as a dopamine re... |
|
T0204 |
Protriptyline hydrochloride
|
Protriptyline HCl |
5-HT Receptor
,
AChE
|
|
Protriptyline Hydrochloride is the hydrochloride salt form of protriptyline, a tricyclic secondary amine with an antidepressant property. Protriptyline hydrochloride (Protriptyline HCl) blocks the re-uptake of norepineph... |
|
T21673 |
N-Isopropylnoratropine
|
|
Others
|
|
N-Isopropylnoratropine is a noratropine derivative and an intermediate in the production of ipratropium, an atropine-like bronchodilator drug via an anticholinergic pathway. N-Isopropylnoratropine is used to examine the ... |
|
T1179 |
Tiotropium bromide
|
Tiopropium,BA679 BR |
AChR
|
|
Tiotropium bromide (BA679 BR) is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). Tiotropium is a muscarinic receptor antagonist, on topical a... |
|
T1540 |
Doxepin hydrochloride
|
Toruan,Doxepin HCl,Aponal,Novoxapin |
P450
,
Dopamine Receptor
,
5-HT Receptor
,
Adrenergic Receptor
,
AChR
,
Norepinephrine
,
Histamine Receptor
|
|
Doxepin hydrochloride (Aponal) is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it ap... |
|
TQ0304 |
Metixene hydrochloride hydrate
|
|
AChR
|
|
|
|
T0089 |
Cetirizine dihydrochloride
|
P071,UCB P071,Cetirizine DiHCl |
Histamine Receptor
|
|
Cetirizine dihydrochloride (UCB P071) is an effective second-generation histamine H1 antagonist that is potent in the therapy of allergic rhinitis, confirmed urticaria, and pollen-induced asthma. Unlike other conventiona... |
|
T1278 |
Astemizole
|
Laridal,Histaminos,Paralergin |
Potassium Channel
,
Histamine Receptor
|
|
Astemizole (Laridal) is a synthetic piperidinyl-benzimidazol derivative with antiallergic properties, acts as a reversible competitive inhibitor of histamine H1 receptors, with less anticholinergic effects compared to re... |
|
T0786 |
Clidinium bromide
|
Ro 2-3773 |
AChR
|
|
Clidinium bromide (Ro 2-3773) , a synthetic anticholinergic agent, has been shown in experimental and clinical researchers to have a pronounced antisecretory and antispasmodic effect on the gastrointestinal tract. It can... |
|
T1442 |
Pizotifen
|
Pizotyline,BC-105 |
5-HT Receptor
|
|
Pizotifen (Pizotyline) is a strong serotonin and tryptamine antagonist, with weak anticholinergic, anti-histaminic and anti-kinin effects. It also possesses sedative and appetite-stimulating properties. Pizotifen hydroch... |
