|
T3111 |
Abemaciclib methanesulfonate
|
abemaciclib mesylate,LY2835219,LY2835219 mesylate,LY2835219 (methanesulfonate) |
CDK
|
|
Abemaciclib methanesulfonate (LY2835219) is a specific and effective inhibitor of CDK4(IC50=2 nM) and CDK6(IC50=10 nM). |
|
T9985 |
Methyl methanesulfonate
|
|
DNA Alkylation
|
|
Methyl methanesulfonate is a DNA alkylator that modifies adenine (3-methyladenine) and guanine (7-methyladenine) respectively, resulting in base mismatch and replication disorders. |
|
T12425 |
PF-06424439 methanesulfonate
|
|
Acyltransferase
,
Transferase
|
|
PF-06424439 methanesulfonate, an orally administered, potent, and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM, demonstrates slow reversibility and time-dependent inh... |
|
T21483 |
Tricaine methanesulfonate
|
MS-222 |
Others
|
|
Tricaine methanesulfonate (MS-222) (TMS) is an anesthetic. Many hatcheries and research studies use TMS to immobilize fish for marking or transport and to suppress sensory systems during invasive procedures. |
|
T38979 |
CYH33 methanesulfonate
|
CYH33 methanesulfonate |
Others
|
|
CYH33 methanesulfonate is a highly selective and orally active inhibitor of PI3Kα, with IC50 values of 5.9 nM, 598 nM, 78.7 nM, and 225 nM against the α, β, δ, and γ isoforms, respectively. This compound effectively inhi... |
|
T13087 |
Tariquidar methanesulfonate, hydrate
|
XR9576 methanesulfonate, hydrate |
Others
|
|
Tariquidar methanesulfonate, hydrate is a potent and specific P-glycoprotein (P-gp) inhibitor(Kd of 5.1 nM). |
|
T1072 |
Loxeen
|
Pridinol methanesulfonate |
AChR
|
|
Loxeen (Pridinol methanesulfonate) is used as an anticholinergic and as an antiparkinsonian agent. |
|
T1275 |
Phentolamine mesylate
|
Phentolamine methanesulfonate,Phentolamine mesilate |
Adrenergic Receptor
|
|
Phentolamine mesylate (Phentolamine methanesulfonate) is a nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEAS... |
|
T25722 |
Lifarizine methanesulfonate
|
|
Others
|
|
Lifarizine methanesulfonate is a modulator of sodium-calcium channel that reduces ischemic brain damage. |
|
T68534 |
FK-448 methanesulfonate
|
|
Others
|
|
FK-448 methanesulfonate is a chymotrypsin inhibitor that has been shown to affect intestinal absorption of insulin in rats and dogs . |
|
T69185 |
INO-1001 methanesulfonate
|
|
Others
|
|
INO-1001 methanesulfonate is an isoindolinone derivative and potent inhibitor of the nuclear enzyme poly (ADP-ribose) polymerase (PARP) with chemosensitization and radiosensitization properties. |
|
T5133 |
Dabigatran Etexilate Mesylate
|
BIBR 1048MS,Dabigatran etexilate methanesulfonate |
Thrombin
|
|
Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI, Ki: 4.5 nM). |
|
T34224 |
Quinacrine methanesulfonate
|
Mepacrine dimethanesulfonate salt |
Others
|
|
Quinacrine methanesulfonate is a bioactive chemical. |
|
T12417 |
PF-04217903 methanesulfonate
|
|
c-Met/HGFR
|
|
PF-04217903 methanesulfonate is a potent ATP-competitive inhibitor of c-Met kinase (Ki of 4.8 nM for human c-Met). |
|
T23148 |
Phenamil methanesulfonate
|
Phenamil |
Others
|
|
TRPP3 channel inhibitor |
|
T2226 |
Pergolide mesylate
|
Pergolide mesylate salt,LY127809,Pergolide methanesulfonate |
Dopamine Receptor
,
5-HT Receptor
,
Adrenergic Receptor
|
|
Pergolide mesylate salt(LY127809) is a long-acting dopamine agonist which has been used to treat PARKINSON DISEASE and HYPERPROLACTINEMIA but withdrawn from some markets due to potential for HEART VALVE DISEASES. |
|
T13567 |
BCX 1470 methanesulfonate
|
|
Serine Protease
|
|
BCX 1470 methanesulfonate inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively. |
|
T71096 |
GCC-4401C methanesulfonate
|
|
Others
|
|
GCC-4401C methanesulfonate is a factor Xa inhibitor similar to rivaroxaban that is currently under development for venous thromboembolic disease (VTE). |
|
T1336 |
Benztropine mesylate
|
Benzotropine mesylate,Benzatropine mesylate,Benztropine methanesulfonate |
Dopamine Receptor
,
AChR
,
Histamine Receptor
|
|
Benztropine mesylate (Benztropine methanesulfonate) is a centrally active muscarinic antagonist that has been used in the symptomatic treatment of PARKINSON DISEASE. Benztropine also inhibits the uptake of dopamine. |
|
T1620 |
Pazufloxacin Mesylate
|
Pazucross,Pazufloxacin mesilate,T-3762,Pazufloxacin methanesulfonate |
Topoisomerase
,
Antibacterial
,
Antibiotic
|
|
Pazufloxacin Mesylate (T-3762) is a fluoroquinolone antibiotic. |
|
T19014 |
Hydroxystilbamidine bis(methanesulfonate)
|
|
Others
|
|
Hydroxystilbamidine bis(methanesulfonate) is a dye capable of binding to both DNA and RNA. It also is a potent inhibitor of cellular ribonucleases. |
|
T26260 |
Tetrabenazine methanesulfonate
|
NSC169886,NSC 169886,NSC-169886 |
Others
|
|
Tetrabenazine methanesulfonate is a medicine formerly utilized as an antipsychotic and therapy for various movement disorders. Tetrabenazine methanesulfonate blocks neurotransmitter uptake into adrenergic storage vesicle... |
|
T6643 |
Ro 31-8220 Mesylate
|
Ro 31-8220 methanesulfonate,Bisindolylmaleimide IX,Bisindolylmaleimide IX mesylate |
PKC
|
|
Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor for PKC-α/βI/βII/γ/ε (IC50: 5/24/14/27/24 nM), and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β. |
|
T30076 |
Aniline, p-(5-phenylpentyloxy)-, methanesulfonate
|
|
Others
|
|
Aniline, p-(5-phenylpentyloxy)-, methanesulfonate is a bioactive chemical. |
|
T33201 |
M-Anisidine, 4-(4-phenylbutoxy)-, methanesulfonate
|
|
Others
|
|
m-Anisidine, 4-(4-phenylbutoxy)-, methanesulfonate is a bioactive chemical. |
|
T34041 |
Phthalimide, N-(2-(p-aminophenoxy)ethyl)-, methanesulfonate
|
|
Others
|
|
Phthalimide, N-(2-(p-aminophenoxy)ethyl)-, methanesulfonate is a bioactive chemical. |
|
T33312 |
4-(Octyloxy)-m-toluidine methanesulfonate
|
Methanesulfonic acid, compd. with 4-(octyloxy)-m-toluidine (7CI) |
Others
|
|
Methanesulfonic acid, compd. with 4-(octyloxy)-m-toluidine (7CI) is a bioactive chemical. |
|
T33522 |
M-Toluidine, 4-(octyloxy)-alpha-(phenylthio)-, methanesulfonate
|
|
Others
|
|
m-Toluidine, 4-(octyloxy)-alpha-(phenylthio)-, methanesulfonate is a bioactive chemical. |
|
T6835 |
Fenoldopam mesylate
|
Fenoldopam methanesulfonate,SKF-82526 mesylate,Corlopam mesylate,mesylate,SKF 82526 |
Dopamine Receptor
|
|
Fenoldopam mesylate (Corlopam mesylate) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation. |
|
T72280 |
PBT434 methanesulfonate
|
|
Others
|
|
PBT434 methanesulfonate is an orally active, potent α-synuclein aggregation inhibitor with the ability to cross the blood-brain barrier. Acting as an iron chelator, it modulates transcellular iron trafficking, inhibits i... |
|
T65157 |
Ethyl methanesulfonate
|
|
Others
|
|
Ethyl methanesulfonate is a useful organic compound for research related to life sciences. The catalog number is T65157 and the CAS number is 62-50-0. |
|
T34042 |
Phthalimide, N-(3-(p-aminophenoxy)propyl)-, methanesulfonate
|
|
Others
|
|
Phthalimide, N-(3-(p-aminophenoxy)propyl)-, methanesulfonate is a bioactive chemical. |
|
T33181 |
M-Anisidine, 4-((5-(benzyloxy)pentyl)oxy)-, methanesulfonate
|
|
Others
|
|
m-Anisidine, 4-((5-(benzyloxy)pentyl)oxy)-, methanesulfonate is a bioactive chemical. |
|
T69008 |
Paroxol methanesulfonate
|
|
Others
|
|
Paroxol methanesulfonate is an intermediate in the synthesis of Paroxetine, a selective serotonin reuptake inhibitor. |
|
T69165 |
Methiothepin methanesulfonate
|
|
Others
|
|
Methiothepin methanesulfonate is an inhibitor of HCV infection and cell-to-cell transmission that acts by targeting the HCV E2 glycoprotein. |
|
T65303 |
Phenyl methanesulfonate
|
|
Others
|
|
Phenyl methanesulfonate is a useful organic compound for research related to life sciences. The catalog number is T65303 and the CAS number is 16156-59-5. |
|
T13108L |
Pamufetinib mesylate
|
TAS-115 mesylate,TAS-115 methanesulfonate |
Others
|
|
TAS-115 mesylate is a potent inhibitor of VEGFR and hepatocyte growth factor receptor (c-Met/HGFR)-targeted kinase(IC50s of 30 and 32 nM for rVEGFR2 and rMET, respectively). |
|
T67318 |
1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole methanesulfonate
|
|
Others
|
|
1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole methanesulfonate is a useful organic compound for research related to life sciences. The catalog number is T67318 and the CAS number is 86386-77-8. |
|
T71094 |
CD4 (81-92)
|
|
Others
|
|
CD4 (81-92) is a peptide that was previously found to inhibit gp120 binding, HIV-1 infectivity, and syncytium formation. |
|
T67219 |
(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol methanesulfonate
|
|
Others
|
|
(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol methanesulfonate is a useful organic compound for research related to life sciences. The catalog number is T67219 and the CAS number is 1175536-50-1... |
|
T66687 |
[(2-Di-cyclohexylphosphino-3,6-dimethoxy-2′,4′,6′- triisopropyl-1,1′-biphenyl)-2-(2′-amino-1,1′ -biphenyl)]palladium(II) methanesulfonate
|
|
Others
|
|
[(2-Di-cyclohexylphosphino-3,6-dimethoxy-2′,4′,6′- triisopropyl-1,1′-biphenyl)-2-(2′-amino-1,1′ -biphenyl)]palladium(II) methanesulfonate is a useful organic compound for research related to life sciences. The catalog nu... |
|
T69989 |
(S)-Pomalidomide
|
|
Others
|
|
(S)-Pomalidomide is an inhibitor of angiogenesis and growth of B-cell neoplasias, which induces complete regressions of Burkitt's lymphoma cell tumors. |
|
T70460 |
HM5023507
|
|
Others
|
|
HM5023507, an orally active dual inhibitor of δγ isoforms in immune signaling. HM5023507 inhibited PI3Kδ and PI3Kγ isoforms with greater than 100-fold selectivity against PI3Kα and PI3Kβ in recombinant enzymatic assays a... |
|
T70995 |
GSK-256066
|
|
Others
|
|
GSK-256066 is a PDE4 inhibitor. |
|
T70357 |
CM-546
|
|
Others
|
|
CM-546 is the trans-isomer of CM-414, and a dual inhibitor of PDE5 and HDACs. |
|
T11381 |
Pictilisib dimethanesulfonate
|
GDC-0941 dimethanesulfonate,GDC-0941 2 MeSO3H salt |
Apoptosis
,
DNA-PK
,
PI3K
,
mTOR
,
Autophagy
|
|
Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold). |
|
T11553 |
Heptamidine dimethanesulfonate
|
SBi4211 dimethanesulfonate |
Others
|
|
Heptamidine dimethanesulfonate (SBi4211 dimethanesulfonate) serves as a potent inhibitor related to Pentamidine, targeting the calcium-binding protein S100B with a dissociation constant (Kd) of 6.9 µM. It demonstrates sp... |
|
T13689 |
Ethylene dimethanesulfonate
|
|
Apoptosis
|
|
Ethylene dimethanesulfonate has selective pro-apoptotic effects on LCs. Ethylene dimethanesulfonate is a mild alkylating, non-volatile methanesulfonic diester of ethylene glycol. |
|
T13817L |
Phen-DC3 Trifluoromethanesulfonate
|
Phen-DC3 Triflate |
Others
|
|
|
|
T83100 |
Antibacterial agent 161 trifluoromethanesulfonate
|
|
Others
|
|
Compound 6 (Antibacterial agent 161, trifluoromethanesulfonate) exhibits antibacterial properties and demonstrates significant antiproliferative effects against colon cancer and non-small cell lung cancer [1]. |
