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Search Results for " phagocytosis "

ターゲット

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天然化合物

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T39789	BMS-986235	BMS-986235,LAR-1219	Others
	BMS-986235 (LAR-1219) is a selective and orally active agonist of formyl peptide receptor 2 (FPR2) with EC50s of 0.41 nM and 3.4 nM for hFPR2 and mFPR2, respectively. BMS-986235 can be used in studies about the preventio...		Others
T4982	Benznidazol	Radanil,Benznidazole,Ro 71051,Ro 07-1051	Antibiotic , Parasite
	Benznidazol (Benznidazole)e has an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production and stimulating host phagocytosis.		Antibiotic , Parasite
T11069	DO-264		Others
	DO-264 is an inhibitor of autohydrolase structural domain 12 (ABHD12) (IC50: 11 nM) and an inhibitor of cellular LysoPS degradation that enhances LPS-induced phagocytosis.		Others
T68166L	Traxanox TFA	Traxanox TFA(58712-69-9 Free base)	Others
	Traxanox TFA is an orally available diuretic. Traxanox TFA enhances phagocytosis of yeast granules by mouse peritoneal macrophages or rat peritoneal polymorphonuclear leukocytes in vitro. Traxanox TFA restores inhibition...		Others
T39308	Boc-Asp(OMe)-fluoromethyl ketone	Boc-Asp(OMe)-fluoromethyl ketone,Boc-Asp(OMe)-FMK	Caspase
	Boc-Asp(OMe)-fluoromethyl ketone (Boc-Asp(OMe)-FMK) is a broad range caspase inhibitor. Boc-Asp(OME)-Fluoromethyl Ketone inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemot...		Caspase
T72024	ZIM
	ZIM, a norbornene derivative of 4-Aminoantipyrine, effectively induces DNA damage, leading to genomic and chromosomal alterations, cell death, and phagocytosis activation. Its properties highlight its potential as a chem...
T77362	Vorsetuzumab	SGN-70	Immunology/Inflammation related
	Vorsetuzumab (Anti-Human CD70 Recombinant Antibody) is a monoclonal antibody targeting the CD70 antibody. Vorsetuzumab has anticancer activity and can enhance the macrophage-associated phagocytosis of kidney cancer cells...		Immunology/Inflammation related
T68166	Traxanox		Others
	Traxanox is an orally available diuretic.Traxanox enhances phagocytosis of yeast granules by mouse peritoneal macrophages or rat peritoneal polymorphonuclear leukocytes in vitro.Restorative effect of Traxanox on inhibiti...		Others
T33613	NCGC00135472	NCGC 00135472,DRV1 (GPR32) agonist C2A,C2A,NCGC-00135472	Others
	NCGC00135472 (DRV1 (GPR32) agonist C2A) is a human Resolvin DI receptor DRV1 agonist with pro-catabolic properties that activates the human soluble protein D1 receptor DRV1/GPR32 receptor in beta-blocker and cAMP assays ...		Others
TP1042	Palmitoyl Tetrapeptide-3	Rigin	Others
	Palmitoyl Tetrapeptide-3 (Rigin) (Rigin) is a synthetic peptide, corrspending to 341-344 amino acid sequence of IgG human H-chain, with phagocytosis stimulating activity.Palmitoyl Tetrapeptide-3 stimulates expression of ...		Others
T34917	Traxanox sodium	Y 12141,Y12141,Y-12141	Others
	Traxanox sodium is an orally available diuretic. Traxanox sodium enhances phagocytosis of yeast granules by mouse peritoneal macrophages or rat peritoneal polymorphonuclear leukocytes in vitro. Traxanox sodium restores i...		Others
T77065	Ligufalimab
	Ligufalimab (AK 117), a humanized IgG4 monoclonal antibody targeting CD47, does not lead to red blood cell (RBC) hemagglutination but promotes phagocytosis and exhibits anti-tumor activity [1].
T37907	DL 175
	Potent and selective GPR84 biased agonist (EC50 = 33 nM). Exhibits no significant activity in a panel of 168 other GPCRs. Exhibits bias for G protein signaling pathways. Induces morphological changes in primary murine bo...
T76677	Dacetuzumab
	Dacetuzumab (SGN-40), a humanized IgG1 anti-CD40 monoclonal antibody, exhibits anti-lymphoma activity by inducing tumor cell death through immune effector functions (antibody-dependent cellular cytotoxicity and phagocyto...
T37259	14(S)-HDHA		Others
	Docosahexaenoic acid is a nutritionally-derived ω-3 fatty acid that is abundant in the brain and the retina and is thought to be important in early development and for therapeutic approaches to inflammatory disorders and...		Others
T78323	Letaplimab	IBI-188
	Letaplimab (IBI-188), a humanized IgG4 monoclonal antibody targeting CD47—which is often overexpressed in cancer cells and acts as a ligand for SIRPα—has been shown to promote phagocytosis of tumor cells [1].
T73564	DMUP
	DMUP, a potent inhibitor of the CD47-SIRPα axis, effectively induces apoptosis and enhances macrophage phagocytosis in A549 cells while reducing the expression of CD47 and SIRPα proteins, exhibiting significant antitumor...
T78277	ATG-031
	ATG-031 is a humanized monoclonal antibody targeting CD24 that promotes macrophage-mediated phagocytosis and induces cancer cell destruction by inhibiting the "don't eat me" signals associated with various cancer growths...
T78552	PB118		Others
	PB118 has the capacity to effectively clear Aβ deposits by augmenting phagocytosis, enhance the tubulin/microtubule network through increased acetyl α-tubulin levels, modulate various inflammation-associated cytokines an...		Others
T63139	Glutaminyl cyclases-IN-1		Others
	Glutaminyl cyclases-IN-1 (IsoQC-IN-1) is a potent inhibitor of Glutaminyl cyclases (QC), which acts on human QC (IC50: 12 nM) and isoQC (IC 50:73 nM). Glutaminyl cyclases-IN-1 inhibited isoQC and selectively blocked CD47...		Others
T35773	Gliotoxin-13C13	Gliotoxin-13C13
	Gliotoxin-13C13is intended for use as an internal standard for the quantification of gliotoxin by GC- or LC-MS. Gliotoxin is an immunosuppressive mycotoxin produced by pathogenic strains ofAspergillusand other fungi with...
T37503	Maresin 2	3R,14S-diHDHA	Others
	Docosahexaenoic acid is an ω-3 fatty acid that is abundant in the brain and the retina and is known to be important in early development.[1] [2] Maresin 2 (MaR2) is a 13R,14S-dihydroxy DHA formed by recombinant human mac...		Others
T80762	XmAb 5592
	XmAb 5592 is a humanized, Fc-engineered antibody targeting HM1.24 with improved affinity for both FcγRIIIa and FcγRIIa receptors. It enhances lysis of HM1.24-specific multiple myeloma (MM) cells through both antibody-dep...
T37505	MCTR1	MCTR1
	Maresin conjugates in tissue regeneration 1 (MCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages at the site of inflammation. DHA is oxidized to maresin 1 , which is ...
T82994	Anzurstobart	BMS-986351,CC-95251
	Anzurstobart (CC-95251; BMS-986351), a fully human monoclonal anti-SIRPα antibody with high affinity, inhibits CD47-SIRPα interaction. It potentiates macrophage-mediated phagocytosis of DLBCL cell lines in co-culture ass...
T37606	Resolvin D5	7(S),17(S)-diHDHA
	Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid . [1] In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory respons...
T81605	Ontorpacept	TTI-621
	Ontorpacept (TTI-621) is a soluble fusion protein comprising the N-terminal (1-118) of human SIRPα fused to the Fc region of human IgG1. This N-terminal (1-118) segment serves as the binding domain for CD47, an inhibitor...
T37506	MCTR2	MCTR2
	Maresin conjugates in tissue regeneration 2 (MCTR2) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages at the site of inflammation. DHA is oxidized to maresin 1 , which is ...
T78450	4-Di-1-ASP
	4-Di-1-ASP, a styryl dye, selectively stains glioma cells within live brain tissue, facilitating microscopic analysis of cell structure, viability, and processes including proliferation, endocytosis, cytokinesis, and pha...
T38042	Resolvin D4	Resolvin D4,RvD4
	Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid . [1] It has been detected in human milk, in the dorsal pouch of mice before and after infection with S. aureus, and in untreat...
T83661	17(R,S)-Benzo-Resolvin D1	17(R,S)-Benzo-RvD1,Benzo-RvD1
	Benzo-resolvin D1 (benzo-RvD1), a derivative of the specialized pro-resolving mediator (SPM) RvD1, effectively reduces PDGF-BB-induced cytoskeletal alterations and PDGF-triggered migration in isolated human vascular smoo...
T37507	MCTR3	MCTR3
	Maresin conjugates in tissue regeneration 3 (MCTR3) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages. DHA is oxidized to maresin 1 , which is converted to MCTR1 by glutat...
T85108	17(R)-Resolvin D3
	17(R)-Resolvin D3 (17(R)-RvD3) is an aspirin-triggered epimer of resolvin D3, produced from docosahexaenoic acid (DHA) through the action of COX-2 in the presence of aspirin, via a 17(R)-hydroperoxy DHA (17(R)-HDHA) inte...
T37166	RCTR1
	Resolvin conjugate in tissue regeneration 1 (RCTR1) is a specialized pro-resolving mediator (SPM) biosynthesized from docosahexaenoic acid by isolated human macrophages and apoptotic polymorphonuclear (PMN) neutrophils.1...
T83847	SP-A (196-215) (human) TFA	Surfactant Protein A,SPA4
	Surfactant protein A (SP-A) (196-215) is a synthetic peptide derived from the C-terminal carbohydrate recognition domain of human SP-A, specifically amino acids 196-215. This peptide suppresses LPS-induced TNF-α release ...
T36679	Rp-cAMPS sodium salt
	Rp-cAMPS sodium salt, a cAMP analog, is a potent, competitive cAMP-induced activation of cAMP-dependent PKA I and II (Kis of 12.5 μM and 4.5 μM, respectively) antagonist. Rp-cAMPS sodium salt is resistant to hydrolysis b...

Compounds

BMS-986235

T39789

Synonym: BMS-986235,LAR-1219

Target: Others

Benznidazol

T4982

Synonym: Radanil,Benznidazole,Ro 71051,Ro 07-1051

Target: Antibiotic, Parasite

Synonym: Traxanox TFA(58712-69-9 Free base)

Target: Others

Boc-Asp(OMe)-fluoromethyl ketone

T39308

Synonym: Boc-Asp(OMe)-fluoromethyl ketone,Boc-Asp(OMe)-FMK

Target: Immunology/Inflammation related

Synonym: NCGC 00135472,DRV1 (GPR32) agonist C2A,C2A,NCGC-00135472

Target: Others

Palmitoyl Tetrapeptide-3

Synonym: Y 12141,Y12141,Y-12141

Glutaminyl cyclases-IN-1

Synonym: Gliotoxin-13C13

Target:

Maresin 2

T37503

Synonym: 3R,14S-diHDHA

Synonym: BMS-986351,CC-95251

Target:

Resolvin D5

T37606

Synonym: 7(S),17(S)-diHDHA

Synonym: Resolvin D4,RvD4

Target:

17(R,S)-Benzo-Resolvin D1

T83661

Synonym: 17(R,S)-Benzo-RvD1,Benzo-RvD1

SP-A (196-215) (human) TFA

T83847

Synonym: Surfactant Protein A,SPA4

カタログ番号	製品名	別名	ターゲット
T13864	Resolvin D1	RvD1	Apoptosis
	Resolvin D1 (RvD1) is an endogenous pro-inflammatory mediator that blocks pro-inflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α-mediated inflammation in macrophages, and enhances macroph...		Apoptosis
T8276	Methyl palmitoleate		Others
	O-PHOSPHO-L-SERINE is an ester of serine and phosphate, which are normal metabolites in human biofluids.O-phospho-L-serine is a phagocytosis inhibitor that inhibits glial cell proliferation and cone cell regeneration aft...		Others
T5057	DL-O-Phosphoserine	DL-2-Amino-3-hydroxypropanoic acid 3-phosphate,O-PHOSPHO-L-SERINE,DL-SOP	Others , Endogenous Metabolite
	O-PHOSPHO-L-SERINE is an ester of serine and phosphate, which are normal metabolites in human biofluids.O-phospho-L-serine is a phagocytosis inhibitor that inhibits glial cell proliferation and cone cell regeneration aft...		Others , Endogenous Metabolite
T4706	Uridine-5'-diphosphate disodium salt	UDP disodium salt,Uridine 5'-diphosphate disodium salt hyd	DNA/RNA Synthesis , Endogenous Metabolite , P2Y Receptor
	Uridine-5'-diphosphate disodium salt (UDP disodium salt) is a specific agonist of the P2Y6 receptors (EC50 = 13 nM for human P2Y6), stimulating the production of inflammatory mediators, phagocytosis, and vasoconstriction...		DNA/RNA Synthesis , Endogenous Metabolite , P2Y Receptor
TL0007	Bisdemethoxycurcumin	Curcumin III,Didemethoxycurcumin	Epigenetic Reader Domain , Wnt/beta-catenin
	Bisdemethoxycurcumin (Curcumin III) is a natural demethoxy derivative of curcumin. It is a potent activator of macrophage phagocytosis, interacting with 1α, 25-dihydroxy vitamin D3 to stimulate amyloid-β clearance by mac...		Epigenetic Reader Domain , Wnt/beta-catenin
T65269	L-Aspartic acid potasium salt	Aspartic acid potasium salt,Potassium L-aspartate	Others
	L-aspartic acid potasium salt（VX-548） is an amino acid widely found in plants and animals.L-aspartic acid potasium salt drives the production of nitrogen oxides, which promotes phagocytosis and contributes to fish surviv...		Others
T3229	Cytochalasin D		ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
	Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertilization processes such as sperm penetration or sperm head dec...		ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
TN5880	Mesuol
	Mesuol has antioxidant activity, it shows very high scavenging activity against DPPH radical; it also has immunomodulatory activity, can potentiate percentage neutrophil adhesion in neutrophil adhesion test in rats and p...
TN3125	5-Methoxycanthin-6-one		Others
	5-Methoxycanthin-6-one displays moderate cytotoxic activity against the human prostate cancer cell PC-3 line, with IC50 values ranging from 13.5-15.4 uM versus doxorubicine with IC50 = 1.5 uM. It also exhibits a clear su...		Others

天然物製品

Synonym: DL-2-Amino-3-hydroxypropanoic acid 3-phosphate,O-PHOSPHO-L-SERINE,DL-SOP

Target: Others, Endogenous Metabolite

Uridine-5'-diphosphate disodium salt

T4706

Synonym: UDP disodium salt,Uridine 5'-diphosphate disodium salt hyd

Target: DNA/RNA Synthesis, Endogenous Metabolite, P2Y Receptor

Bisdemethoxycurcumin

TL0007

Synonym: Curcumin III,Didemethoxycurcumin

Target: Epigenetic Reader Domain, Wnt/beta-catenin

L-Aspartic acid potasium salt

T65269

Synonym: Aspartic acid potasium salt,Potassium L-aspartate

Target: ATPase, p38 MAPK, Calcium Channel, Akt, PI3K

5-Methoxycanthin-6-one

TN3125

Synonym:

Target: Others

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-01850	CEACAM3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66...
TMPH-03717	YopE Protein, Yersinia enterocolitica, Recombinant (His)	Yersinia enterocolitica	E. coli
	Essential virulence determinant; cytotoxic effector, involved in resistance to phagocytosis.
TMPY-00517	LSP1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	LSP1 (Lymphocyte Specific Protein 1) is a Protein Coding gene. This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regula...
TMPH-01047	CEACAM4 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Granulocyte orphan receptor that acts as an trigger efficient phagocytosis of attached particles. CEACAM4 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 14.7 k...
TMPK-00598	Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	The Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-depende...
TMPH-01046	CEACAM4 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Granulocyte orphan receptor that acts as an trigger efficient phagocytosis of attached particles. CEACAM4 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predict...
TMPH-03578	SCIN Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a ...
TMPH-03719	YopH Protein, Yersinia enterocolitica, Recombinant (His & Myc)	Yersinia enterocolitica	E. coli
	Essential virulence determinant. This protein is a protein tyrosine phosphatase. The essential function of YopH in Yersinia pathogenesis is host-protein dephosphorylation. It contributes to the ability of the bacteria to...
TMPK-00599	Fc gamma RIIIA/CD16a (V176) Domain 2 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent r...
TMPK-00597	Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent r...
TMPK-00546	TIM-1/KIM-1/HAVCR1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Kidney injury molecule 1 (KIM-1, also known as TIM-1) is markedly upregulated in the proximal tubule after injury and is maladaptive when chronically expressed. KIM-1-mediated epithelial cell phagocytosis of apoptotic ce...
TMPK-01022	MERTK/Mer Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mu...
TMPH-02441	IL-15 Protein, Rhesus macaque, Recombinant (His)	Rhesus	P. pastoris (Yeast)
	Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA. In neutrophils, stimula...
TMPK-00791	Fc gamma RIIIA/CD16a (F176) Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent r...
TMPK-00144	CEACAM3 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	The human granulocyte-specific receptor carcinoembryonic antigen-related cell adhesion molecule (CEACAM)3 is critically involved in the opsonin-independent recognition of several bacterial pathogens. CEACAM3-mediated pha...
TMPK-00759	IgG1 Fc Protein, Human, Recombinant	Human	HEK293 Cells
	IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR) on phagocytic cells with high affinity. Fc fragment is demonstrated to mediate phagocytosis, trigger inflam...
TMPK-00760	IgG1 Fc Protein, Mouse, Recombinant	Mouse	HEK293 Cells
	Recombinant murine Fc fragment contains the hinge region, CH2, and CH3 region of the mouse IgG1 isotype. IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR) on...
TMPH-03577	Staphopain B Protein, S. aureus, Recombinant (GST)	Staphylococcus aureus	E. coli
	Cysteine protease that plays an important role in the inhibition of host innate immune response. Degrades host elastin, fibrogen, fibronectin and kininogen. Blocks phagocytosis of opsonised S. aureus by neutrophils and m...
TMPK-00460	Fc gamma RIIIB/CD16b (NA2) Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Human Fc gamma RIIIB/CD16b Protein is a receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate a...
TMPK-00418	MERTK/Mer Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mu...
TMPK-00792	Fc gamma RIIIA/CD16a (F176) Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent r...
TMPH-03528	Chemotaxis inhibitory Protein, S. aureus (strain NCTC 8325/PS47), Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leu...
TMPK-01139	TIM-1/KIM-1/HAVCR1 Protein, Human, Recombinant (aa 21-295, His)	Human	HEK293 Cells
	Kidney injury molecule 1 (KIM-1, also known as TIM-1) is markedly upregulated in the proximal tubule after injury and is maladaptive when chronically expressed. KIM-1-mediated epithelial cell phagocytosis of apoptotic ce...
TMPK-00417	MERTK/Mer Protein, Human, Recombinant (His)	Human	HEK293 Cells
	MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mu...
TMPH-02658	FPR1 Protein, Mouse, Recombinant (GST & His & Myc)	Mouse	E. coli
	High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release...
TMPH-03529	Chemotaxis inhibitory Protein, S. aureus (strain MRSA252), Recombinant (His)	Staphylococcus aureus	P. pastoris (Yeast)
	Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leu...
TMPH-02500	AIF-1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage acti...
TMPK-00459	Fc gamma RIIIB/CD16b (NA2) Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Human Fc gamma RIIIB/CD16b Protein is a receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate a...
TMPH-01346	FPR1 Protein, Human, Recombinant (GST & His & Myc)	Human	E. coli
	High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release...
TMPJ-00766	ANXA1 Protein, Human, Recombinant	Human	E. coli
	Annexin A1 is the first characterized member of the annexin family of proteins and is able to bind to cellular membranes in a calcium-dependent manner, promoting membrane fusion and endocytosis. Annexin A1 has anti-infla...
TMPY-03337	Iba1 Protein, Human, Recombinant (His)	Human	E. coli
	AIF1, also known as IBA1, is an actin-binding protein. AIF1 is expressed selectively in human macrophage-like cell lines, and in a subset of CD68(+) macrophages in the interstitial and perivascular spaces of human hear...
TMPY-00176	FNDC4 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	FNDC4 acts as an anti-inflammatory factor on macrophages and improves mouse model of induced colitis. FNDC4 could suppress osteoclast formation via NF-kappaB pathway and downregulation of CXCL10. Analysis of binding of F...
TMPJ-00437	Fetuin A Protein, Macaca mulatta, Recombinant (His)	Macaca mulatta	HEK293 Cells
	Alpha-2-HS-glycoprotein (AHSG) is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the Cystatin family of proteases inhibitors. It is highly expressed in embryonic cells and adult hepatocyt...
TMPJ-00621	LILRB1/CD85j/ILT2 Protein, Rhesus macaque, Recombinant (aa 17-456, His)	Rhesus	HEK293 Cells
	LILRB1, also known as CD85j and ILT2, is a transmembrane glycoprotein in the LILR immunoregulatory protein family. LILRB1 is expressed on NK cells that have expanded in response to acute HCMV infection. LILRB1 exhibits c...
TMPJ-00306	SIRP alpha Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can expre...
TMPY-02439	Rac2 Protein, Human, Recombinant (His)	Human	E. coli
	Ras-related C3 botulinum toxin substrate 2 (Rac2) is a small G-protein belonging to the Ras subfamily of the GTPase family. Rac2 acts as an "on / off" switch for signal transduction cascades and motilities. When GDP is a...
TMPJ-01159	CD16/FCGR3 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Low affinity immunoglobulin gamma Fc region receptor III (Fc gamma RIII/CD16) is a member of the Ig superfamily. Based on close relationships in their extracellular domains, the Fc gamma Rs have been divided into three c...
TMPH-03267	CD300f/CD300LF Protein, Rat, Recombinant (His & Myc & SUMO)	Rat	E. coli
	Acts as an inhibitory receptor for myeloid cells and mast cells. Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition; recognizes and binds PS as a ligand which...
TMPJ-01182	SIRP alpha Protein, Mouse, Recombinant (MIgG2a)	Mouse	HEK293 Cells
	SIRPα is a type I transmembrane glycoprotein.It contains two Ig-like C1-type domains and one Ig-like V-type domain. Mouse SIRP alpha ECD shares 61%, 75%, 62%, 61%, and 59% aa sequence identity with human, rat, equine, bo...
TMPJ-00305	SIRP alpha Protein, Cynomolgus, Recombinant (aa 31-369, His)	Cynomolgus	HEK293 Cells
	Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can expre...
TMPJ-01143	MERTK/Mer Protein, Human, Recombinant (aa 1-323, His)	Human	HEK293 Cells
	Tyrosine-protein kinase Mer (MERTK) is a single-pass type I membrane protein which belongs to the MER/AXL/TYRO3 receptor kinase family. MERTK include two fibronectin type-III domains, two Ig-like C2-type domains, and one...
TMPJ-00534	HFcgR4 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Fcgr4, also known as CD16-2, is one of the receptors for Fc region of IgG which involve in immune responses. Fcgr4 mainly functions in cellular response to lipopolysaccharide, NK T cell proliferation, regulation of senso...
TMPJ-00751	IgG4 hFc Protein, Human, Recombinant (aa 99-326)	Human	HEK293 Cells
	As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma ...
TMPJ-00446	CD32A Protein, Human, Recombinant (R167, His)	Human	HEK293 Cells
	Receptors for the Fc region of IgG (FcγR) are members of the Ig superfamily that function in the activation or inhibition of immune responses. Human FcγRs are divided into three classes designated FcγRI (CD64), FcγRII (C...
TMPY-01187	Rac1 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	RAC1 is a GTPase that belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal re...

CEACAM3 Protein, Human, Recombinant (His)

TMPY-01850

Species: Human

Expression System: HEK293 Cells

YopE Protein, Yersinia enterocolitica, Recombinant (His)

TMPH-03717

Species: Yersinia enterocolitica

Expression System: E. coli

LSP1 Protein, Human, Recombinant (His)

TMPY-00517

Species: Human

Expression System: HEK293 Cells

CEACAM4 Protein, Human, Recombinant (His)

TMPH-01047

Species: Human

Expression System: P. pastoris (Yeast)

Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00598

Species: Human

Expression System: HEK293 Cells

CEACAM4 Protein, Human, Recombinant (E. coli, His)

TMPH-01046

Species: Human

Expression System: E. coli

SCIN Protein, S. aureus, Recombinant (His & Myc)

TMPH-03578

Species: Staphylococcus aureus

Expression System: E. coli

YopH Protein, Yersinia enterocolitica, Recombinant (His & Myc)

TMPH-03719

Species: Yersinia enterocolitica

Expression System: E. coli

Fc gamma RIIIA/CD16a (V176) Domain 2 Protein, Human, Recombinant (mFc)

TMPK-00599

Species: Human

Expression System: HEK293 Cells

Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi)

TMPK-00597

Species: Human

Expression System: HEK293 Cells

TIM-1/KIM-1/HAVCR1 Protein, Cynomolgus, Recombinant (His)

TMPK-00546

Species: Cynomolgus

Expression System: HEK293 Cells

MERTK/Mer Protein, Mouse, Recombinant (His)

TMPK-01022

Species: Mouse

Expression System: HEK293 Cells

IL-15 Protein, Rhesus macaque, Recombinant (His)

TMPH-02441

Species: Rhesus

Expression System: P. pastoris (Yeast)

Fc gamma RIIIA/CD16a (F176) Protein, Human, Recombinant (His & Avi)

TMPK-00791

Species: Human

Expression System: HEK293 Cells

CEACAM3 Protein, Human, Recombinant (hFc)

TMPK-00144

Species: Human

Expression System: HEK293 Cells

IgG1 Fc Protein, Human, Recombinant

TMPK-00759

Species: Human

Expression System: HEK293 Cells

IgG1 Fc Protein, Mouse, Recombinant

TMPK-00760

Species: Mouse

Expression System: HEK293 Cells

Staphopain B Protein, S. aureus, Recombinant (GST)

TMPH-03577

Species: Staphylococcus aureus

Expression System: E. coli

Fc gamma RIIIB/CD16b (NA2) Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00460

Species: Human

Expression System: HEK293 Cells

MERTK/Mer Protein, Human, Recombinant (mFc)

TMPK-00418

Species: Human

Expression System: HEK293 Cells

Fc gamma RIIIA/CD16a (F176) Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00792

Species: Human

Expression System: HEK293 Cells

Chemotaxis inhibitory Protein, S. aureus (strain NCTC 8325/PS47), Recombinant (His & Myc)

TMPH-03528

Species: Staphylococcus aureus

Expression System: E. coli

TIM-1/KIM-1/HAVCR1 Protein, Human, Recombinant (aa 21-295, His)

TMPK-01139

Species: Human

Expression System: HEK293 Cells

MERTK/Mer Protein, Human, Recombinant (His)

TMPK-00417

Species: Human

Expression System: HEK293 Cells

FPR1 Protein, Mouse, Recombinant (GST & His & Myc)

TMPH-02658

Species: Mouse

Expression System: E. coli

Chemotaxis inhibitory Protein, S. aureus (strain MRSA252), Recombinant (His)

TMPH-03529

Species: Staphylococcus aureus

Expression System: P. pastoris (Yeast)

AIF-1 Protein, Mouse, Recombinant (His)

TMPH-02500

Species: Mouse

Expression System: E. coli

Fc gamma RIIIB/CD16b (NA2) Protein, Human, Recombinant (His & Avi)

TMPK-00459

Species: Human

Expression System: HEK293 Cells

FPR1 Protein, Human, Recombinant (GST & His & Myc)

TMPH-01346

Species: Human

Expression System: E. coli

ANXA1 Protein, Human, Recombinant

TMPJ-00766

Species: Human

Expression System: E. coli

Iba1 Protein, Human, Recombinant (His)

TMPY-03337

Species: Human

Expression System: E. coli

FNDC4 Protein, Human, Recombinant (mFc)

TMPY-00176

Species: Human

Expression System: HEK293 Cells

Fetuin A Protein, Macaca mulatta, Recombinant (His)

TMPJ-00437

Species: Macaca mulatta

Expression System: HEK293 Cells

LILRB1/CD85j/ILT2 Protein, Rhesus macaque, Recombinant (aa 17-456, His)

TMPJ-00621

Species: Rhesus

Expression System: HEK293 Cells

SIRP alpha Protein, Human, Recombinant (His & Avi), Biotinylated

TMPJ-00306

Species: Human

Expression System: HEK293 Cells

Rac2 Protein, Human, Recombinant (His)

TMPY-02439

Species: Human

Expression System: E. coli

CD16/FCGR3 Protein, Mouse, Recombinant (His)

TMPJ-01159

Species: Mouse

Expression System: HEK293 Cells

CD300f/CD300LF Protein, Rat, Recombinant (His & Myc & SUMO)

TMPH-03267

Species: Rat

Expression System: E. coli

SIRP alpha Protein, Mouse, Recombinant (MIgG2a)

TMPJ-01182

Species: Mouse

Expression System: HEK293 Cells

SIRP alpha Protein, Cynomolgus, Recombinant (aa 31-369, His)

TMPJ-00305

Species: Cynomolgus

Expression System: HEK293 Cells

MERTK/Mer Protein, Human, Recombinant (aa 1-323, His)

TMPJ-01143

Species: Human

Expression System: HEK293 Cells

hFcgR4 Protein, Mouse, Recombinant (His)

TMPJ-00534

Species: Mouse

Expression System: HEK293 Cells

IgG4 hFc Protein, Human, Recombinant (aa 99-326)

TMPJ-00751

Species: Human

Expression System: HEK293 Cells

CD32A Protein, Human, Recombinant (R167, His)

TMPJ-00446

Species: Human

Expression System: HEK293 Cells

Rac1 Protein, Human, Recombinant (GST)

TMPY-01187

Species: Human

Expression System: Baculovirus Insect Cells

カタログ番号	製品名
L7500	Coagulation and Anticoagulation Compound Library	144 compounds
	A unique collection of 144 procoagulation and anticoagulation related compounds for high throughput screening (HTS) and high content screening (HCS);
L9000	Apoptosis Compound Library	1760 compounds
	A unique collection of 1760 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;

ライブラリー

Coagulation and Anticoagulation Compound Library

L7500

Compounds: 144

Apoptosis Compound Library

L9000

Compounds: 1760