|
T1491 |
Atovaquone
|
Atavaquone |
Others
,
P450
,
Dehydrogenase
,
Antibiotic
,
Parasite
|
|
Atovaquone (Atavaquone) is a hydroxynaphthoquinone that has antimicrobial activity and is being used in antimalarial protocols. |
|
T6231 |
Tebipenem Pivoxil
|
ME1211,Orapenem |
Antibacterial
,
Antibiotic
|
|
Tebipenem Pivoxil (Orapenem) , an orally activity carbapenem antibiotic, is utilized in treating otolaryngologic and respiratory infections. |
|
T23133 |
Pentamidine
|
|
Phosphatase
,
Antibacterial
,
Antibiotic
,
Parasite
,
Antifungal
|
|
Pentamidine is an antifungal and antiprotozoal agent, interacting directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor groove of DNA, thereby interfering with DNA replication. |
|
T4267 |
Tulathromycin A
|
CP 472295,Draxxin,Tulathromycin |
Antibacterial
,
Antibiotic
|
|
Tulathromycin A (CP 472295) is a macrolide antibiotic. |
|
T2691 |
Oritavancin diphosphate
|
LY333328 diphosphate |
Others
,
Antibacterial
,
Antibiotic
|
|
Oritavancin diphosphate (LY333328 diphosphate) is a novel semisynthetic glycopeptide antibiotic which is being developed for the treatment of serious Gram-positive bacterial infections. |
|
T5189 |
Omadacycline
|
PTK 0796,Amadacycline |
ribosome
,
Antibacterial
,
Antibiotic
|
|
Omadacycline (Amadacycline), a new tetracycline antibiotic, can inhibit the 30s subunit of bacterial ribosome. |
|
T1654 |
Pentamidine isethionate
|
Pentamidine isethionate salt,Pentamidine diisethionate |
Phosphatase
,
Antibacterial
,
Antibiotic
,
Parasite
,
Antifungal
|
|
Pentamidine isethionate (Pentamidine diisethionate) is a synthetic amidine derivative, Pentamidine Isethionate is an antiprotozoal and antifungal agent. |
|
T4201 |
Avibactam sodium
|
AVE-1330A,NXL-104 |
Antibacterial
,
Antibiotic
|
|
Avibactam sodium (NXL-104) is a reversible β-lactamase inhibitor (IC50: 8/80/38 nM, for TEM-1/P99/KPC-2 β-lactamases). |
|
T23132 |
Pentamidine dihydrochloride
|
MP-601205 dihydrochloride |
Phosphatase
,
Antibacterial
,
Antibiotic
,
Parasite
,
Antifungal
|
|
Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an aromatic diamidine agent with activity against a number of microorganisms including protozoa (Trypanosoma brucei, Leishmania spp., and Babesia spp.) and fungi... |
|
T7804 |
Garenoxacin mesylate hydrate
|
Garenoxacin mesylate [USAN],BMS284756 (Mesylate hydrate) |
Antibacterial
|
|
Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) with potent antimicrobial activity, against common respiratory pathogens, including resistant strains. |
|
T0331 |
Moxifloxacin hydrochloride
|
BAY-128039,Moxifloxacin HCl,BAY12-8039 HCl |
Topoisomerase
,
Antibacterial
,
Antibiotic
|
|
Moxifloxacin hydrochloride (BAY12-8039 HCl) is a fourth generation fluoroquinolone with expanded activity against gram-positive bacteria as well as atypical pathogens. Moxifloxacin has been linked to mild ALT elevations ... |
|
T7179 |
Garenoxacin
|
BMS284756 |
Antibacterial
|
|
Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections. |
|
T79088 |
Chlamydia pneumoniae-IN-1
|
|
|
|
Chlamydia pneumoniae-IN-1 (compound 55), a benzimidazole derivative, exhibits potent antibacterial activity, inhibiting 99% of C. pneumoniae growth at a concentration of 10 μM and maintaining 95% viability of the host ce... |
|
T22387 |
NSC 55655
|
5-[(2-nitrophenyl)methylidene]thiazolidine-2,4-dione |
Others
|
|
NSC 55655 (5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione) possesses antimicrobial and antioxidant activities and inhibits the proliferation of B. subtilis, S. aureus, K. pneumonia, E. coli, S. typhi , A. niger and C... |
|
T12242 |
Norvancomycin hydrochloride
|
Desmethyl-vancomycin hydrochloride |
Antibacterial
|
|
Norvancomycin hydrochloride (Desmethyl-vancomycin hydrochloride) is used as a treatment for endocarditis, osteomyelitis, pneumonia, sepsis, or soft tissue infections caused by Staphylococcus. |
|
T11785 |
KT203
|
|
MAGL
|
|
KT203 is a selective and potent structural domain 6 (ABHD6) inhibitor of alpha/beta hydrolytic enzymes with potential antiviral and anti-inflammatory activity for the study of pneumonia. |
|
T11815 |
Lanopepden
|
GSK 1322322,GSK-1322322B,GSK-1322322J |
Antibiotic
|
|
Lanopepden (GSK 1322322) is a potent peptide deformylase inhibitor of Staphylococcus aureus, inhibiting ATCC 29213 and ATCC 25923 strains, and can be used in the study of pneumonia, dermatological and infectious diseases... |
|
T10987 |
Decarboxy Moxifloxacin
|
|
Others
|
|
Decarboxy Moxifloxacin is a decarboxylated compound of moxifloxacin. Moxifloxacin is an oral active 8-methoxyquinolone antibiotic used in acute bacterial sinusitis, chronic bronchitis, acute bacterial deterioration, and ... |
|
T4553 |
Procaine penicillin G
|
Duphapen,Hydracillin,Hostacillin |
Antibiotic
|
|
Procaine penicillin G (Duphapen) (procaine benzylpenicillin) is an antibiotic useful for the treatment of a number of bacterial infections. Specifically, it is used for syphilis, anthrax, mouth infections, pneumonia, dip... |
|
T39933 |
Bexotegrast
|
PLN-74809 |
Integrin
|
|
Bexotegrast (PLN-74809) is an orally active and potent inhibitor of αvβ6 and αvβ1 integrins with antifibrotic effects, inhibits αvβ6 and αvβ1-induced activation of TGF-β, and can be used for the study of idiopathic pulmo... |
|
T1492 |
Gemifloxacin mesylate
|
LB-20304a,SB-265805S,Gemifloxacin mesylate |
DNA gyrase
,
Topoisomerase
,
Antibacterial
|
|
Gemifloxacin mesylate (Gemifloxacin mesylate) inhibits activities of DNA gyrase and topoisomerase IV, thereby inhibiting DNA replication and eventually bacterial growth. Gemifloxacin Mesylate is the mesylate salt form of... |
|
T77125 |
Otilimab
|
GSK 3196165,MOR103 |
CSF-1R
|
|
Otilimab (GSK 3196165) is a humanized monoclonal antibody against granulocyt-macrophage colony-stimulating factor (GM-CSF). Otilimab has anti-inflammatory activity, regulates the biological function of GM-CSF by blocking... |
|
T11836 |
Lefamulin acetate
|
BC-3781 acetate |
ribosome
,
Antibacterial
,
Antibiotic
|
|
Lefamulin acetate (BC-3781 acetate) (formally BC-3781 acetate) is a novel pleuromutilin antibiotic and is the first to be used for the systemic treatment of bacterial infections in humans. Lefamulin acetate (BC-3781 acet... |
|
T1283 |
Clinafloxacin
|
PD 127391,CI-960,AM-1091 |
Antibacterial
,
Antibiotic
|
|
Clinafloxacin (CI-960)(PD-127391) is a fluoroquinolone antibiotic. |
|
T1293L |
Gatifloxacin sesquihydrate
|
Gatifloxacin |
|
|
Gatifloxacin sesquihydrate, a bacterial DNA gyrase inhibitor, is used to treat tuberculosis and pneumonia. |
|
T28997 |
TP-271
|
TP271 |
|
|
TP-271, a tetracyclines antibiotic, is used potentially for the treatment of community-acquired bacterial pneumonia (CABP). |
|
T16428 |
Pafuramidine
|
DB289 |
Others
|
|
Pafuramidine is an orally bioavailable prodrug of furamidine. It has activity against Pneumocystis pneumonia (IC50 value: 4.5 nM) |
|
T32891 |
L-Primaquine
|
BRN0019337,BRN-0019337,BRN 0019337 |
|
|
l-Primaquine is used to treat and prevent malaria and to treat Pneumocystis pneumonia. |
|
T23622 |
Acorafloxacin HCl
|
JNJ-32729463,JNJ-Q2 hydrochloride,Acorafloxacin hydrochloride,JNJ 32729463,JNJ-Q2 HCl |
|
|
Acorafloxacin is a broad-spectrum fluoroquinolone antibacterial drug being developed for the treatment of acute bacterial skin and skin structure infections and community-acquired pneumonia. |
|
T17210 |
Vaborbactam
|
RPX7009 |
Antibacterial
|
|
Vaborbactam (RPX7009) is a β-lactamase inhibitor that is often used in conjunction with meropenem to study pneumonia and CRE infections. |
|
T10420 |
Avarofloxacin
|
JNJ-Q2 |
Others
|
|
Avarofloxacin (JNJ-Q2) is a broad-spectrum fluoroquinolone antibacterial drug being developed for the treatment of acute bacterial skin and community-acquired pneumonia and skin structure infections. |
|
T61123 |
Antibacterial agent 111
|
|
|
|
Antibacterial agent 111 (Compound 3) exhibits potent antibacterial activity against B. cereus and K. pneumonia, with MIC values of 3.90 μg/mL and 0.49 μg/mL, respectively. It achieves this antibacterial effect by strongl... |
|
T38586 |
Grepafloxacin
|
dl-Grepafloxacin,OPC-17116 |
|
|
Grepafloxacin (OPC-17116) is a fluoroquinolone antibiotic that is administered orally. It possesses strong efficacy against community-acquired respiratory pathogens, notably Streptococcus pneumonia. Grepafloxacin exhibit... |
|
TP2139 |
AMY-101
|
Cp40 |
Others
|
|
AMY-101 is a peptidic inhibitor of the central complement component C3 (KD: 0.5 nM). AMY-101 shows a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation. |
|
T9931 |
Meplazumab
|
|
Others
|
|
meplazumab is a humanized anti-CD147 antibody, as add-on therapy in patients with COVID-19 pneumonia. |
|
T40971 |
Dehydroandrographolide succinate potassium sodium salt
|
|
|
|
Dehydroandrographolide succinate (potassium sodium salt), derived from the herbal medicine Andrographis paniculata (Burm f) Nees, is a versatile compound highly utilized for the treatment of viral pneumonia and viral upp... |
|
T36993 |
Moxifloxacin N-Sulfate (sodium salt)
|
|
|
|
Moxifloxacin N-sulfate is a metabolite of moxifloxacin . Moxifloxacin is a fluoroquinolone antibiotic. Formulations containing moxifloxacin have been used in the treatment of bacterial infections, including sinusitis, ch... |
|
TP2139L |
AMY-101 TFA
|
Cp40 TFA |
Others
|
|
AMY-101 TFA (Cp40 TFA) is a peptidic inhibitor of the central complement component C3 (KD: 0.5 nM). AMY-101 TFA shows a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper in... |
|
T19198 |
Atovaquone-d4
|
|
Others
|
|
Atovaquone D4 is the deuterium-labeled Atovaquone. Atovaquone is a medication used to treat or prevent pneumocystis babesia, malaria, toxoplasmosis, and pneumonia. |
|
T19678 |
Cefaloridine
|
Cephaloridine,Sch 11527 |
|
|
Cefaloridine is a first-generation semisynthetic derivative of cephalosporin C. It is unique among cephalosporins in that it exists as a zwitterion. Cephaloridine was very effective to cure pneumococcal pneumonia. It has... |
|
T39862 |
Trimethoprim lactate
|
|
|
|
Trimethoprim lactic is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim lactic is active against a wide range of Gram-positive and Gram-negative aerobic bacteria . Trimetho... |
|
T77174 |
Efmarodocokin alfa
|
|
|
|
Efmarodocokin alfa, a fusion protein combining human IL-22 with the IgG4 crystallizable fragment, activates IL-22 signaling. This compound has potential applications in the study of severe COVID-19 pneumonia [1]. |
|
T60569 |
Sulfametrole
|
|
|
|
Sulfametrole is an orally active and potent antibacterial that can be used in the research of infections, for example, HIV, severe pneumonia, and UTIs (urinary tract infections) [1] [2]. |
|
T60238 |
Acloproxalap
|
|
|
|
Acloproxalap is a quinoline-based aldehyde scavenger that can be used in studies of diseases with toxic aldehyde accumulation, such as inflammatory diseases of the eye and skin, respiratory diseases such as pneumonia, or... |
|
T74821 |
Nemonoxacin
|
|
|
|
Nemonoxacin (TG-873870), a potent, orally active broad-spectrum antibiotic, demonstrates strong inhibitory activity against various species of staphylococci, streptococci, and enterococci, as well as Neisseria gonorrhoea... |
|
T37283 |
1-Palmitoyl Lysophosphatidic Acid (sodium salt)
|
|
|
|
1-Palmitoyl lysophosphatidic acid (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of five different G protein-coupled receptors (GPCRs) to mediate a variety of biological... |
|
T70642 |
Lanopepden camsylate
|
|
|
|
Lanopepden, also known as GSK-1322322 or GSK-322, is a potent and selective peptide deformylase inhibitor with good in vitro activity against bacteria associated with community-acquired pneumonia and skin infections. GSK... |
|
T76320 |
FIZZ-1 (32-51) (mouse)
|
|
|
|
FIZZ-1 (32-51) (mouse), a cysteine-rich secretory protein, is predominantly expressed in macrophages, bronchial epithelial, and type II alveolar epithelial cells (AEC) during allergic airway inflammation. Additionally, i... |
|
T71266 |
Omadacycline HCl
|
|
|
|
Omadacycline, also known as PTK 0796 and Amadacyclin, is a novel first-in-class aminomethylcycline with potent activity against important skin and pneumonia pathogens, including community-acquired methicillin-resistant S... |
|
T76990 |
Suvratoxumab
|
|
|
|
Suvratoxumab (MEDI4893) is a high-affinity, long-acting humanized IgG1κ anti-α-toxin monoclonal antibody. It effectively neutralizes α-toxin, a principal virulence factor of S. aureus, enhancing survival and diminishing ... |
