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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T12546 | Prolyl Endopeptidase Inhibitor 1 | (Boc)-Prolyl-prolinal,BPP,Boc-Pro-prolinal | Others |
Prolyl Endopeptidase Inhibitor 1 is a potent inhibitor of prolyl endopeptidase (PEP; PE)(Ki : 15 nM) , has anti-amnesic effect. | |||
T8657 | KYP-2047 | Others | |
KYP-2047 is a very potent, selective Prolyl oligopeptidase (POP) inhibitor. | |||
T9855 | BR102910 | 4-Thiazolecarboxamide, N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-2-[(3,4-dichlorophenyl)methyl]- | Others |
BR102910 (4-Thiazolecarboxamide, N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-2-[(3,4-dichlorophenyl)methyl]-) is a selective inhibitor of fibroblast activated protein (FAP). | |||
T35233 | Y-29794 Tosylate | Y 29794,Y29794 tosylate,Y29794,Y-29794 | Prolyl Endopeptidase (PREP) |
Y-29794 Tosylate (Y-29794) is an orally active, effective, and specific non-peptide-prolyl endopeptidase (PPCE) inhibitor. | |||
T17279 | Z-321 | Others | |
Z-321 is an inhibitor of prolyl endopeptidase. | |||
T23541 | Y-29794 oxalate | Others | |
Inhibitor of prolyl endopeptidase | |||
T26659 | ARI-3531 | ARI 3531 | Others |
ARI-3531 is a selective prolyl endopeptidase inhibitor. | |||
T25973 | Poststatin | Others | |
Poststatin is a prolyl endopeptidase inhibitor produced by Streptomyces viridochromogenes MH534-30F3. | |||
T28246 | ONO-1603 | ONO1603 | Others |
ONO-1603, a prolyl endopeptidase inhibitor, is used potentially for the treatment of Alzheimer's disease. | |||
T25955 | Picromycin | Antibiotic B 62169A,Amaromycin,Albomycetin,Pikromycin | Others |
Picromycin is a 14-membered macrolide antibiotic and Prolyl endopeptidase (PREP) inhibitor. Pikromycin shows activity against gram-positive bacteria including mycobacteria. | |||
T74044 | Z-Pro-prolinal | Others | |
Z-Pro-prolinal (N-Benzyloxycarbonyl-L-prolyl-L-prolinal) serves as a specific and orally active inhibitor of prolyl endopeptidase (PREP), demonstrating an IC50 value of 0.4 nM against porcine PREP [1] [2] [3]. | |||
T61684 | S 17092 | Others | |
S 17092 (S 17092-1) is a highly effective inhibitor of cerebral prolyl-endopeptidase (PEP), displaying an IC50 value of 1.2 nM. It is utilized in research focused on understanding memory impairment and cognitive disorder... | |||
T74674 | Z-Thioprolyl-Thiazolidine | Others | |
Z-Thioprolyl-Thiazolidine is a potent, specific inhibitor of bovine brain prolyl endopeptidase, demonstrating an inhibition constant (K i value) of 0.36 nM [1]. | |||
T74673 | Z-Thioprolyl-Thioproline | Others | |
Z-Thioprolyl-Thioproline is a prolyl endopeptidase inhibitor derived from bovine brain, exhibiting inhibition constants of IC50 = 16 µM and Ki = 37 µM. This compound is utilized in the investigation of neurological disor... | |||
T80106 | Z-Pro-Pro-aldehyde-dimethyl acetal | Prolyl Endopeptidase (PREP) | |
Z-Pro-Pro-aldehyde-dimethyl acetal is a potent prolyl endopeptidase (PREP) inhibitor, effectively impeding the activity of this cytoplasmic serine endoprotease with an IC50 of 12 nM. Its significance is underscored by it... | |||
T70365 | JTP-4819 | Others | |
JTP-4819 is a potent and selective prolyl endopeptidase (PEP) inhibitor with potential for treating Alzheimer's disease. At nanomolar concentration, JTP-4819 inhibited the degradation of substance P, arginine-vasopressin... | |||
T83875 | HUP-55 | Others | |
HUP-55 is a prolyl endopeptidase inhibitor with an IC50 of 5 nM, shown to mitigate α-synuclein dimerization in Neuro2a cells, stimulate autophagy in HEK293 cells, and lower hydrogen peroxide-evoked reactive oxygen specie... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TN4442 | Linderene acetate | Prolyl Endopeptidase (PREP) | |
Linderene acetate is a competitive inhibitor against Prolyl endopeptidase. | |||
T2717 | Salidroside | Rhodioloside | Apoptosis , mTOR |
Salidroside (Rhodioloside) is a bioactive phenolic glycoside compound isolated from Rhodiola crenulata. It is a prolyl endopeptidase Inhibitor. | |||
T3891 | Oroxylin A-7-O-glucuronide | Oroxylin A Glucoronide,Oroxyloside,Oroxylin A 7-O-beta-D-glucuronide | Others |
Oroxylin A-7-O-glucuronide (Oroxylin A Glucoronide) and wogonoside should also be served as the chemical markers together with baicalin for the quality control of herbs and proprietary traditional Chinese medicine (PTCM)... | |||
T2S0618 | β-Elemonic Acid | 3-oxo Tirucallic Acid,Beta-Elemonic acid,3-Oxotirucallenoic Acid,Elemadienonic Acid | Apoptosis , Reactive Oxygen Species , COX |
β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects. Beta-Elemonic acid inhibits proliferation by inducing hypoploid cells and cell apoptosis, the anticancer effects of beta-Elemonic acid are rel... | |||
T2775 | Baicalin | Baicalein 7-O-β-D-glucuronide | NF-κB , HIV Protease , GABA Receptor , Autophagy |
Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV properties. | |||
T2858 | Baicalein | 5,6,7-Trihydroxyflavone | Ferroptosis , Influenza Virus , ROS , Xanthine Oxidase |
Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor. | |||
TN4917 | Rosenonolactone | Others | |
Rosenonolactone shows inhibitory activity against prolyl endopeptidase and thrombin. | |||
TN7543 | (S)-Laudanosine | NSC 35045,L-(+)-Laudanosine,(+)-Laudanosine,L-Laudanosine | Others |
(S)-Laudanosine, the (S) enantiomer of laudanosine, emerges as a metabolite from the neuromuscular blocking agents atracurium and cisatracurium. It functions by inhibiting prolyl endopeptidase and obstructing arachidonic... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-03269 | Prolyl Endopeptidase Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
Prolyl endopeptidase, also known as PREP, belongs to a distinct class of serine peptidases. It is a large cytosolic enzyme which was first described in the cytosol of rabbit brain as an oligopeptidase. Prolyl endopeptida... |