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Search Results for " prolyl endopeptidase "

ターゲット

17

阻害剤

8

天然化合物

1

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T12546 Prolyl Endopeptidase Inhibitor 1 (Boc)-Prolyl-prolinal,BPP,Boc-Pro-prolinal Others
Prolyl Endopeptidase Inhibitor 1 is a potent inhibitor of prolyl endopeptidase (PEP; PE)(Ki : 15 nM) , has anti-amnesic effect.
T8657 KYP-2047 Others
KYP-2047 is a very potent, selective Prolyl oligopeptidase (POP) inhibitor.
T9855 BR102910  4-Thiazolecarboxamide, N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-2-[(3,4-dichlorophenyl)methyl]- Others
BR102910 (4-Thiazolecarboxamide, N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-2-[(3,4-dichlorophenyl)methyl]-) is a selective inhibitor of fibroblast activated protein (FAP).
T35233 Y-29794 Tosylate Y 29794,Y29794 tosylate,Y29794,Y-29794 Prolyl Endopeptidase (PREP)
Y-29794 Tosylate (Y-29794) is an orally active, effective, and specific non-peptide-prolyl endopeptidase (PPCE) inhibitor.
T17279 Z-321 Others
Z-321 is an inhibitor of prolyl endopeptidase.
T23541 Y-29794 oxalate Others
Inhibitor of prolyl endopeptidase
T26659 ARI-3531 ARI 3531 Others
ARI-3531 is a selective prolyl endopeptidase inhibitor.
T25973 Poststatin Others
Poststatin is a prolyl endopeptidase inhibitor produced by Streptomyces viridochromogenes MH534-30F3.
T28246 ONO-1603 ONO1603 Others
ONO-1603, a prolyl endopeptidase inhibitor, is used potentially for the treatment of Alzheimer's disease.
T25955 Picromycin Antibiotic B 62169A,Amaromycin,Albomycetin,Pikromycin Others
Picromycin is a 14-membered macrolide antibiotic and Prolyl endopeptidase (PREP) inhibitor. Pikromycin shows activity against gram-positive bacteria including mycobacteria.
T74044 Z-Pro-prolinal Others
Z-Pro-prolinal (N-Benzyloxycarbonyl-L-prolyl-L-prolinal) serves as a specific and orally active inhibitor of prolyl endopeptidase (PREP), demonstrating an IC50 value of 0.4 nM against porcine PREP [1] [2] [3].
T61684 S 17092 Others
S 17092 (S 17092-1) is a highly effective inhibitor of cerebral prolyl-endopeptidase (PEP), displaying an IC50 value of 1.2 nM. It is utilized in research focused on understanding memory impairment and cognitive disorder...
T74674 Z-Thioprolyl-Thiazolidine Others
Z-Thioprolyl-Thiazolidine is a potent, specific inhibitor of bovine brain prolyl endopeptidase, demonstrating an inhibition constant (K i value) of 0.36 nM [1].
T74673 Z-Thioprolyl-Thioproline Others
Z-Thioprolyl-Thioproline is a prolyl endopeptidase inhibitor derived from bovine brain, exhibiting inhibition constants of IC50 = 16 µM and Ki = 37 µM. This compound is utilized in the investigation of neurological disor...
T80106 Z-Pro-Pro-aldehyde-dimethyl acetal Prolyl Endopeptidase (PREP)
Z-Pro-Pro-aldehyde-dimethyl acetal is a potent prolyl endopeptidase (PREP) inhibitor, effectively impeding the activity of this cytoplasmic serine endoprotease with an IC50 of 12 nM. Its significance is underscored by it...
T70365 JTP-4819 Others
JTP-4819 is a potent and selective prolyl endopeptidase (PEP) inhibitor with potential for treating Alzheimer's disease. At nanomolar concentration, JTP-4819 inhibited the degradation of substance P, arginine-vasopressin...
T83875 HUP-55 Others
HUP-55 is a prolyl endopeptidase inhibitor with an IC50 of 5 nM, shown to mitigate α-synuclein dimerization in Neuro2a cells, stimulate autophagy in HEK293 cells, and lower hydrogen peroxide-evoked reactive oxygen specie...
カタログ番号 製品名 別名 ターゲット
TN4442 Linderene acetate Prolyl Endopeptidase (PREP)
Linderene acetate is a competitive inhibitor against Prolyl endopeptidase.
T2717 Salidroside Rhodioloside Apoptosis , mTOR
Salidroside (Rhodioloside) is a bioactive phenolic glycoside compound isolated from Rhodiola crenulata. It is a prolyl endopeptidase Inhibitor.
T3891 Oroxylin A-7-O-glucuronide Oroxylin A Glucoronide,Oroxyloside,Oroxylin A 7-O-beta-D-glucuronide Others
Oroxylin A-7-O-glucuronide (Oroxylin A Glucoronide) and wogonoside should also be served as the chemical markers together with baicalin for the quality control of herbs and proprietary traditional Chinese medicine (PTCM)...
T2S0618 β-Elemonic Acid 3-oxo Tirucallic Acid,Beta-Elemonic acid,3-Oxotirucallenoic Acid,Elemadienonic Acid Apoptosis , Reactive Oxygen Species , COX
β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects. Beta-Elemonic acid inhibits proliferation by inducing hypoploid cells and cell apoptosis, the anticancer effects of beta-Elemonic acid are rel...
T2775 Baicalin Baicalein 7-O-β-D-glucuronide NF-κB , HIV Protease , GABA Receptor , Autophagy
Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV properties.
T2858 Baicalein 5,6,7-Trihydroxyflavone Ferroptosis , Influenza Virus , ROS , Xanthine Oxidase
Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor.
TN4917 Rosenonolactone Others
Rosenonolactone shows inhibitory activity against prolyl endopeptidase and thrombin.
TN7543 (S)-Laudanosine NSC 35045,L-(+)-Laudanosine,(+)-Laudanosine,L-Laudanosine Others
(S)-Laudanosine, the (S) enantiomer of laudanosine, emerges as a metabolite from the neuromuscular blocking agents atracurium and cisatracurium. It functions by inhibiting prolyl endopeptidase and obstructing arachidonic...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-03269 Prolyl Endopeptidase Protein, Mouse, Recombinant (His) Mouse Baculovirus Insect Cells
Prolyl endopeptidase, also known as PREP, belongs to a distinct class of serine peptidases. It is a large cytosolic enzyme which was first described in the cytosol of rabbit brain as an oligopeptidase. Prolyl endopeptida...